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Select item 49902051.

Autophagy differentially regulates distinct breast cancer stem-like cells in murine models via EGFR/Stat3 and Tgfß/Smad signaling

Syn Kok Yeo, Jian Wen, Song Chen, Jun-Lin Guan

Cancer Res. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Cancer Res. 2016 Jun 1; 76(11): 3397–3410. Published online 2016 Apr 13. doi: 10.1158/0008-5472.CAN-15-2946

PMCID:: PMC4990205

Abstract Article PDF–1.2M

Select item 45028152.

Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium

Jingyu Yao, Lin Jia, Naheed Khan, Chengmao Lin, Sayak K Mitter, Michael E Boulton, Joshua L Dunaief, Daniel J Klionsky, Jun-Lin Guan, Debra A Thompson, David N Zacks

Autophagy. 2015 Jun; 11(6): 939–953. Published online 2015 Jun 15. doi: 10.1080/15548627.2015.1041699

PMCID:: PMC4502815

Abstract Article PDF–2.0M

Select item 38057193.

Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation

Fei Liu, Fang Fang, Hebao Yuan, Dongye Yang, Yongqiang Chen, Linford Williams, Steven A. Goldstein, Paul H. Krebsbach, Jun-Lin Guan

J Bone Miner Res. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: J Bone Miner Res. 2013 Nov; 28(11): 2414–2430. doi: 10.1002/jbmr.1971

PMCID:: PMC3805719

Abstract Article PDF–8.9M

Select item 31752754.

Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anti-cancer agents

Heekyong Bae, Jun-Lin Guan

Mol Cancer Res. Author manuscript; available in PMC 2012 Sep 1.

Published in final edited form as: Mol Cancer Res. 2011 Sep; 9(9): 1232–1241. Published online 2011 Aug 1. doi: 10.1158/1541-7786.MCR-11-0098

PMCID:: PMC3175275

Abstract Article PDF–1.8M

Select item 31439415.

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

Huijun Wei, Shuang Wei, Boyi Gan, Xu Peng, Weiping Zou, Jun-Lin Guan

Genes Dev. 2011 Jul 15; 25(14): 1510–1527. doi: 10.1101/gad.2051011

PMCID:: PMC3143941

Abstract Article PDF–2.0M

Select item 28234596.

Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration

Chun-Chi Liang, Chenran Wang, Xu Peng, Boyi Gan, Jun-Lin Guan

J Biol Chem. 2010 Jan 29; 285(5): 3499–3509. Published online 2009 Nov 24. doi: 10.1074/jbc.M109.072389

PMCID:: PMC2823459

Abstract Article PDF–4.7M

Select item 100926467.

CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy

Shunsuke Ishii, Haruka Chino, Koji L. Ode, Yoshitaka Kurikawa, Hiroki R. Ueda, Akira Matsuura, Noboru Mizushima, Eisuke Itakura

Mol Biol Cell. 2023 Apr 1; 34(4): ar29. Published online 2023 Mar 7. doi: 10.1091/mbc.E22-09-0432

PMCID:: PMC10092646

Abstract Article PDF–13M

Select item 99469358.

Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling

Fuchun Yang, Shiva Kalantari, Banzhan Ruan, Shaogang Sun, Zhaoqun Bian, Jun-Lin Guan

Nat Commun. 2023; 14: 978. Published online 2023 Feb 22. doi: 10.1038/s41467-023-36562-5

PMCID:: PMC9946935

Abstract Article PDF–3.7M

Select item 83223369.

FIP200 restricts RNA virus infection by facilitating RIG-I activation

Lingyan Wang, Kun Song, Wenzhuo Hao, Yakun Wu, Girish Patil, Fang Hua, Yiwen Sun, Chaoqun Huang, Jerry Ritchey, Clinton Jones, Lin Liu, Jun-Lin Guan, Shitao Li

Commun Biol. 2021; 4: 921. Published online 2021 Jul 29. doi: 10.1038/s42003-021-02450-1

PMCID:: PMC8322336

Abstract Article PDF–3.3M

Select item 731110410.

Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells

Chenran Wang, Michael A. Haas, Fuchun Yang, Syn Yeo, Takako Okamoto, Song Chen, Jian Wen, Pranjal Sarma, David R. Plas, Jun-Lin Guan

Nat Metab. Author manuscript; available in PMC 2020 Jun 23.

Published in final edited form as: Nat Metab. 2019 Nov; 1(11): 1127–1140. Published online 2019 Nov 11. doi: 10.1038/s42255-019-0137-5

PMCID:: PMC7311104

Abstract Article PDF–6.8M

Select item 712496711.

The autophagy protein, FIP200 (RB1CC1) mediates progesterone responses governing uterine receptivity and decidualization

Arin K Oestreich, Sangappa B Chadchan, Alexandra Medvedeva, John P Lydon, Emily S Jungheim, Kelle H Moley, Ramakrishna Kommagani

Biol Reprod. 2020 Apr; 102(4): 843–851. Published online 2020 Jan 4. doi: 10.1093/biolre/ioz234

PMCID:: PMC7124967

Abstract Article PDF–1.2M

Select item 680108512.

Autophagy regulates craniofacial bone acquisition

Neil Thomas, Han Kyoung Choi, Xiaoxi Wei, Li Wang, Yuji Mishina, Jun-Lin Guan, Fei Liu

Calcif Tissue Int. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Calcif Tissue Int. 2019 Nov; 105(5): 518–530. Published online 2019 Aug 1. doi: 10.1007/s00223-019-00593-2

PMCID:: PMC6801085

Abstract Article PDF–2.1M

Select item 482640013.

Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model

Song Chen, Chenran Wang, Syn Yeo, Chun-Chi Liang, Takako Okamoto, Shaogang Sun, Jian Wen, Jun-Lin Guan

Genes Dev. 2016 Apr 1; 30(7): 856–869. doi: 10.1101/gad.276428.115

PMCID:: PMC4826400

Abstract Article PDF–1.8M

Select item 439374114.

FIP200 is Involved in Murine Pseudomonas Infection by Regulating HMGB1 Intracellular Translocation

Yi Li, Chang-pei Gan, Shuang Zhang, Xi-kun Zhou, Xue-feng Li, Yu-quan Wei, Jin-liang Yang, Min Wu

Cell Physiol Biochem. Author manuscript; available in PMC 2015 May 20.

Published in final edited form as: Cell Physiol Biochem. 2014; 33(6): 1733–1744. Published online 2014 May 20. doi: 10.1159/000362954

Correction in:: Cell Physiol Biochem, volume 33 on page 2014

PMCID:: PMC4393741

Abstract Article PDF–906K

Select item 406138215.

Autophagy Deficiency by Hepatic FIP200 Deletion Uncouples Steatosis From Liver Injury in NAFLD

Di Ma, Matthew M. Molusky, Jianrui Song, Chun-Rui Hu, Fang Fang, Crystal Rui, Anna V. Mathew, Subramaniam Pennathur, Fei Liu, Ji-Xin Cheng, Jun-Lin Guan, Jiandie D. Lin

Mol Endocrinol. 2013 Oct; 27(10): 1643–1654. Published online 2013 Aug 19. doi: 10.1210/me.2013-1153