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Select item 80863811.

SLX4IP Promotes Telomere Maintenance in Androgen Receptor–Independent Castration-Resistant Prostate Cancer through ALT-like Telomeric PML Localization

Tawna L. Mangosh, Wisam N. Awadallah, Magdalena M. Grabowska, Derek J. Taylor

Mol Cancer Res. Author manuscript; available in PMC 2021 Apr 30.

Published in final edited form as: Mol Cancer Res. 2021 Feb; 19(2): 301–316. Published online 2020 Nov 13. doi: 10.1158/1541-7786.MCR-20-0314

PMCID:: PMC8086381

Abstract Article PDF–2.5M

Select item 70325702.

SLX4IP and telomere dynamics dictate breast cancer metastasis and therapeutic responsiveness

Nathaniel J Robinson, Chevaun D Morrison-Smith, Alex J Gooding, Barbara J Schiemann, Mark W Jackson, Derek J Taylor, William P Schiemann

Life Sci Alliance. 2020 Apr; 3(4): e201900427. Published online 2020 Feb 18. doi: 10.26508/lsa.201900427

PMCID:: PMC7032570

Abstract Article PDF–3.0M

Select item 68634663.

SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance

Stephanie Panier, Marija Maric, Graeme Hewitt, Emily Mason-Osann, Himabindu Gali, Anqi Dai, Adam Labadorf, Jean-Hugues Guervilly, Philip Ruis, Sandra Segura-Bayona, Ondrej Belan, Paulina Marzec, Pierre-Henri L. Gaillard, Rachel L. Flynn, Simon J. Boulton

Mol Cell. 2019 Oct 3; 76(1): 27–43.e11. doi: 10.1016/j.molcel.2019.07.010

PMCID:: PMC6863466

Abstract Article

Select item 42894294.

Non-covalent Interactions with SUMO and Ubiquitin Orchestrate Distinct Functions of the SLX4 Complex in Genome Maintenance

Jian Ouyang, Elizabeth Garner, Alexander Hallet, Hai Dang Nguyen, Kimberly A. Rickman, Grace Gill, Agata Smogorzewska, Lee Zou

Mol Cell. Author manuscript; available in PMC 2016 Jan 8.

Published in final edited form as: Mol Cell. 2015 Jan 8; 57(1): 108–122. Published online 2014 Dec 18. doi: 10.1016/j.molcel.2014.11.015

PMCID:: PMC4289429

Abstract Article PDF–1.7M

Select item 83538845.

SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling

Nathaniel J. Robinson, Masaru Miyagi, Jessica A. Scarborough, Jacob G. Scott, Derek J. Taylor, William P. Schiemann

Sci Signal. Author manuscript; available in PMC 2021 Dec 29.

Published in final edited form as: Sci Signal. 2021 Jun 29; 14(689): eabe9613. Published online 2021 Jun 29. doi: 10.1126/scisignal.abe9613

PMCID:: PMC8353884

Abstract Article PDF–2.9M

Select item 34645306.

Proliferating Cell Nuclear Antigen (PCNA)-binding Protein C1orf124 Is a Regulator of Translesion Synthesis

Gargi Ghosal, Justin Wai-Chung Leung, Binoj C. Nair, Ka-Wing Fong, Junjie Chen

J Biol Chem. 2012 Oct 5; 287(41): 34225–34233. Published online 2012 Aug 17. doi: 10.1074/jbc.M112.400135

PMCID:: PMC3464530

Abstract Article PDF–1.9M

Select item 68212777.

SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair

Huimin Zhang, Zhen Chen, Yin Ye, Zu Ye, Dan Cao, Yun Xiong, Mrinal Srivastava, Xu Feng, Mengfan Tang, Chao Wang, John A Tainer, Junjie Chen

Nucleic Acids Res. 2019 Nov 4; 47(19): 10181–10201. Published online 2019 Sep 9. doi: 10.1093/nar/gkz769

PMCID:: PMC6821277

Abstract Article PDF–3.8M

Select item 95275208.

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma

Jie Ding, Xiaolong Li, Sabbir Khan, Chen Zhang, Feng Gao, Shayak Sen, Amanda R Wasylishen, Yang Zhao, Guillermina Lozano, Dimpy Koul, W K Alfred Yung

Neuro Oncol. 2022 Oct; 24(10): 1712–1725. Published online 2022 Apr 26. doi: 10.1093/neuonc/noac105

PMCID:: PMC9527520

Abstract Article PDF–12M

Select item 31231159.

The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle

Hans-Jörg Warnatz, Dominic Schmidt, Thomas Manke, Ilaria Piccini, Marc Sultan, Tatiana Borodina, Daniela Balzereit, Wasco Wruck, Alexey Soldatov, Martin Vingron, Hans Lehrach, Marie-Laure Yaspo

J Biol Chem. 2011 Jul 1; 286(26): 23521–23532. Published online 2011 May 9. doi: 10.1074/jbc.M111.220178

PMCID:: PMC3123115

Abstract Article PDF–2.2M

Select item 272068610.

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Jennifer M. Svendsen, Agata Smogorzewska, Mathew E. Sowa, Brenda C. O’Connell, Steven P. Gygi, Stephen J. Elledge, J. Wade Harper

Cell. Author manuscript; available in PMC 2010 Jan 10.

Published in final edited form as: Cell. 2009 Jul 10; 138(1): 63–77. doi: 10.1016/j.cell.2009.06.030

PMCID:: PMC2720686

Abstract Article PDF–6.1M

Select item 272791711.

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex

Jian Ouyang, Yujiang Shi, Alvaro Valin, Yan Xuan, Grace Gill

Mol Cell. Author manuscript; available in PMC 2010 Apr 24.

Published in final edited form as: Mol Cell. 2009 Apr 24; 34(2): 145–154. doi: 10.1016/j.molcel.2009.03.013

PMCID:: PMC2727917

Abstract Article PDF–1.0M

Select item 828276412.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 1024311613.

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt

J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706

PMCID:: PMC10243116

Abstract Article PDF–13M

Select item 1000589814.

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay

J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027

PMCID:: PMC10005898

Abstract Article PDF–6.7M

Select item 860245115.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6

PMCID:: PMC8602451

Abstract Article PDF–11M

Select item 810809316.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary

Cell. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050

PMCID:: PMC8108093

Abstract Article PDF–3.5M

Select item 673589217.

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras

Nucleic Acids Res. 2019 Sep 5; 47(15): 8004–8018. Published online 2019 Jun 10. doi: 10.1093/nar/gkz510

Correction in:: Nucleic Acids Res. 2019 Sep 5; 47(15): 8332.

PMCID:: PMC6735892

Abstract Article PDF–5.4M

Select item 970808618.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 882889519.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 549522520.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114