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Select item 109971031.

Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma

Ida Waern, Srinivas Akula, Venkata Sita Rama Raju Allam, Sowsan Taha, Thorsten B. Feyerabend, Magnus Åbrink, Sara Wernersson

PLoS One. 2024; 19(4): e0300668. Published online 2024 Apr 5. doi: 10.1371/journal.pone.0300668

PMCID:: PMC10997103

Abstract Article PDF–3.3M

Select item 75629012.

Duodenal acidification induces gastric relaxation and alters epithelial barrier function by a mast cell independent mechanism

Hanne Vanheel, Maria Vicario, Dorien Beeckmans, Silvia Cocca, Lucas Wauters, Alison Accarie, Joran Toth, Hans-Reimer Rodewald, Gert De Hertogh, Gianluca Matteoli, Guy Boeckxstaens, Jan Tack, Ricard Farre, Tim Vanuytsel

Sci Rep. 2020; 10: 17448. Published online 2020 Oct 15. doi: 10.1038/s41598-020-74491-1

PMCID:: PMC7562901

Abstract Article PDF–7.3M

Select item 53697613.

Defective bone repair in mast cell-deficient Cpa3^Cre/+ mice

Jose Luis Ramirez-GarciaLuna, Daniel Chan, Robert Samberg, Mira Abou-Rjeili, Timothy H. Wong, Ailian Li, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Janet E. Henderson, Paul A. Martineau

PLoS One. 2017; 12(3): e0174396. Published online 2017 Mar 28. doi: 10.1371/journal.pone.0174396

PMCID:: PMC5369761

Abstract Article PDF–4.1M

Select item 44000164.

Inhibition of Inflammatory Arthritis Using Fullerene Nanomaterials

Anthony L. Dellinger, Pierre Cunin, David Lee, Andrew L. Kung, D. Bradford Brooks, Zhiguo Zhou, Peter A. Nigrovic, Christopher L. Kepley

PLoS One. 2015; 10(4): e0126290. Published online 2015 Apr 16. doi: 10.1371/journal.pone.0126290

PMCID:: PMC4400016

Abstract Article PDF–964K

Select item 11688315.

Loss of Histochemical Identity in Mast Cells Lacking Carboxypeptidase A

Thorsten B. Feyerabend, Heinz Hausser, Annette Tietz, Carmen Blum, Lars Hellman, Anita H. Straus, Hélio K. Takahashi, Ellen S. Morgan, Ann M. Dvorak, Hans Jörg Fehling, Hans-Reimer Rodewald

Mol Cell Biol. 2005 Jul; 25(14): 6199–6210. doi: 10.1128/MCB.25.14.6199-6210.2005

PMCID:: PMC1168831

Abstract Article PDF–1.1M

Select item 106345386.

Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice

Chih-Chung Jerry Lin, Fanny Herisson, Hoang Le, Nader Jaafar, Kashish Chetal, Mary K. Oram, Kelly L. Flynn, Evan P. Gavrilles, Ruslan I. Sadreyev, Felipe L. Schiffino, Rudolph E. Tanzi

Cell Rep. Author manuscript; available in PMC 2023 Nov 9.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113141. Published online 2023 Sep 19. doi: 10.1016/j.celrep.2023.113141

PMCID:: PMC10634538

Abstract Article PDF–2.0M

Select item 53926837.

Experimental Arthritis Is Dependent on Mouse Mast Cell Protease-5

Richard L. Stevens, H. Patrick McNeil, Lislaine A. Wensing, Kichul Shin, G. William Wong, Philip M. Hansbro, Steven A. Krilis

J Biol Chem. 2017 Mar 31; 292(13): 5392–5404. Published online 2017 Feb 13. doi: 10.1074/jbc.M116.773416

PMCID:: PMC5392683

Abstract Article PDF–2.4M

Select item 49250268.

Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction

Anta Ngkelo, Adèle Richart, Jonathan A. Kirk, Philippe Bonnin, Jose Vilar, Mathilde Lemitre, Pauline Marck, Maxime Branchereau, Sylvain Le Gall, Nisa Renault, Coralie Guerin, Mark J. Ranek, Anaïs Kervadec, Luca Danelli, Gregory Gautier, Ulrich Blank, Pierre Launay, Eric Camerer, Patrick Bruneval, Philippe Menasche, Christophe Heymes, Elodie Luche, Louis Casteilla, Béatrice Cousin, Hans-Reimer Rodewald, David A. Kass, Jean-Sébastien Silvestre

J Exp Med. 2016 Jun 27; 213(7): 1353–1374. doi: 10.1084/jem.20160081

PMCID:: PMC4925026

Abstract Article PDF–3.4M

Select item 38870179.

Mast Cells Play No Role in the Pathogenesis of Postoperative Ileus Induced by Intestinal Manipulation

Pedro J. Gomez-Pinilla, Giovanna Farro, Martina Di Giovangiulio, Nathalie Stakenborg, Andrea Némethova, Annick de Vries, Adrian Liston, Thorsten B. Feyerabend, Hans-Reimwer Rodewald, Guy E. Boeckxstaens, Gianluca Matteoli

PLoS One. 2014; 9(1): e85304. Published online 2014 Jan 9. doi: 10.1371/journal.pone.0085304

Correction in:: PLoS One. 2014; 9(1): 10.1371/annotation/99de087d-c3fc-4e9d-9ee9-552b7524f9e1.

PMCID:: PMC3887017

Abstract Article PDF–2.8M

Select item 211848610.

Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin

Lars A. Schneider, Susan M. Schlenner, Thorsten B. Feyerabend, Markus Wunderlin, Hans-Reimer Rodewald

J Exp Med. 2007 Oct 29; 204(11): 2629–2639. doi: 10.1084/jem.20071262

PMCID:: PMC2118486

Abstract Article PDF–1.9M

Select item 29852011.

Cloning of cDNAs that encode human mast cell carboxypeptidase A, and comparison of the protein with mouse mast cell carboxypeptidase A and rat pancreatic carboxypeptidases.

D S Reynolds, D S Gurley, R L Stevens, D J Sugarbaker, K F Austen, W E Serafin

Proc Natl Acad Sci U S A. 1989 Dec; 86(23): 9480–9484. doi: 10.1073/pnas.86.23.9480

PMCID:: PMC298520

Summary Page Browse PDF–1.3M

Select item 761081012.

Local immune response to food antigens drives meal-induced abdominal pain

Javier Aguilera-Lizarraga, Morgane V. Florens, Maria Francesca Viola, Piyush Jain, Lisse Decraecker, Iris Appeltans, Maria Cuende-Estevez, Naomi Fabre, Kim Van Beek, Eluisa Perna, Dafne Balemans, Nathalie Stakenborg, Stavroula Theofanous, Goele Bosmans, Stéphanie U. Mondelaers, Gianluca Matteoli, Sales Ibiza Martinez, Cintya Lopez-Lopez, Josue Jaramillo-Polanco, Karel Talavera, Yeranddy A. Alpizar, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Ricard Farre, Frank A. Redegeld, Jiyeon Si, Jeroen Raes, Christine Breynaert, Rik Schrijvers, Cédric Bosteels, Bart N. Lambrecht, Scott D. Boyd, Ramona A. Hoh, Deirdre Cabooter, Maxim Nelis, Patrick Augustijns, Sven Hendrix, Jessica Strid, Raf Bisschops, David E. Reed, Stephen J. Vanner, Alexandre Denadai-Souza, Mira M. Wouters, Guy E. Boeckxstaens

Nature. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Nature. 2021 Feb 1; 590(7844): 151–156. Published online 2021 Jan 13. doi: 10.1038/s41586-020-03118-2

PMCID:: PMC7610810

Abstract Article PDF–4.4M

Select item 492131613.

Mast Cells Regulate Epidermal Barrier Function and the Development of Allergic Skin Inflammation

Sarita Sehra, Ana PM Serezani, Jesus A. Ocaña, Jeffrey B. Travers, Mark H. Kaplan

J Invest Dermatol. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Invest Dermatol. 2016 Jul; 136(7): 1429–1437. Published online 2016 Mar 25. doi: 10.1016/j.jid.2016.03.019

PMCID:: PMC4921316

Abstract Article PDF–789K

Select item 449775714.

Mast cells mediate malignant pleural effusion formation

Anastasios D. Giannou, Antonia Marazioti, Magda Spella, Nikolaos I. Kanellakis, Hara Apostolopoulou, Ioannis Psallidas, Zeljko M. Prijovich, Malamati Vreka, Dimitra E. Zazara, Ioannis Lilis, Vassilios Papaleonidopoulos, Chrysoula A. Kairi, Alexandra L. Patmanidi, Ioanna Giopanou, Nikolitsa Spiropoulou, Vaggelis Harokopos, Vassilis Aidinis, Dionisios Spyratos, Stamatia Teliousi, Helen Papadaki, Stavros Taraviras, Linda A. Snyder, Oliver Eickelberg, Dimitrios Kardamakis, Yoichiro Iwakura, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Ioannis Kalomenidis, Timothy S. Blackwell, Theodora Agalioti, Georgios T. Stathopoulos

J Clin Invest. 2015 Jun 1; 125(6): 2317–2334. Published online 2015 Apr 27. doi: 10.1172/JCI79840

PMCID:: PMC4497757

Abstract Article PDF–12M

Select item 324521315.

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1^fl/fl mice

Jennifer N. Lilla, Ching-Cheng Chen, Kaori Mukai, Maya J. BenBarak, Christopher B. Franco, Janet Kalesnikoff, Mang Yu, Mindy Tsai, Adrian M. Piliponsky, Stephen J. Galli

Blood. 2011 Dec 22; 118(26): 6930–6938. Prepublished online 2011 Oct 14. doi: 10.1182/blood-2011-03-343962

PMCID:: PMC3245213

Abstract Article

Select item 319546116.

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

Mitsuteru Akahoshi, Chang Ho Song, Adrian M. Piliponsky, Martin Metz, Andrew Guzzetta, Magnus Åbrink, Susan M. Schlenner, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Gunnar Pejler, Mindy Tsai, Stephen J. Galli

J Clin Invest. 2011 Oct 3; 121(10): 4180–4191. Published online 2011 Sep 19. doi: 10.1172/JCI46139

PMCID:: PMC3195461

Abstract Article PDF–1.3M

Select item 582024817.

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

Ian C. Scott, Jayesh B. Majithiya, Caroline Sanden, Peter Thornton, Philip N. Sanders, Tom Moore, Molly Guscott, Dominic J. Corkill, Jonas S. Erjefält, E. Suzanne Cohen

Sci Rep. 2018; 8: 3363. Published online 2018 Feb 20. doi: 10.1038/s41598-018-21589-2

PMCID:: PMC5820248

Abstract Article PDF–2.5M

Select item 566336518.

Mast cell hyperactivity underpins the development of oxygen-induced retinopathy

Kenshiro Matsuda, Noriko Okamoto, Masatoshi Kondo, Peter D. Arkwright, Kaoru Karasawa, Saori Ishizaka, Shinichi Yokota, Akira Matsuda, Kyungsook Jung, Kumiko Oida, Yosuke Amagai, Hyosun Jang, Eiichiro Noda, Ryota Kakinuma, Koujirou Yasui, Uiko Kaku, Yasuo Mori, Nobuyuki Onai, Toshiaki Ohteki, Akane Tanaka, Hiroshi Matsuda

J Clin Invest. 2017 Nov 1; 127(11): 3987–4000. Published online 2017 Oct 9. doi: 10.1172/JCI89893

PMCID:: PMC5663365

Abstract Article PDF–15M

Select item 695999519.

Inflammation-induced IgE promotes epithelial hyperplasia and tumour growth

Mark David Hayes, Sophie Ward, Greg Crawford, Rocio Castro Seoane, William David Jackson, David Kipling, David Voehringer, Deborah Dunn-Walters, Jessica Strid

eLife. 2020; 9: e51862. Published online 2020 Jan 14. doi: 10.7554/eLife.51862

PMCID:: PMC6959995

Abstract Article PDF–2.8M

Select item 427013320.

A next-generation dual-recombinase system for time and host specific targeting of pancreatic cancer

Nina Schönhuber, Barbara Seidler, Kathleen Schuck, Christian Veltkamp, Christina Schachtler, Magdalena Zukowska, Stefan Eser, Thorsten B. Feyerabend, Mariel C. Paul, Philipp Eser, Sabine Klein, Andrew M. Lowy, Ruby Banerjee, Fangtang Yang, Chang-Lung Lee, Everett J. Moding, David G. Kirsch, Angelika Scheideler, Dario R. Alessi, Ignacio Varela, Allan Bradley, Alexander Kind, Angelika E. Schnieke, Hans-Reimer Rodewald, Roland Rad, Roland M. Schmid, Günter Schneider, Dieter Saur

Nat Med. Author manuscript; available in PMC 2014 Dec 18.

Published in final edited form as: Nat Med. 2014 Nov; 20(11): 1340–1347. Published online 2014 Oct 19. doi: 10.1038/nm.3646

Correction in:: Nat Med. 2015 Apr; 21(4): 414.

PMCID:: PMC4270133

Abstract Article PDF–3.1M

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