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Select item 65794721.

Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient Cyp27b1 pseudo-null mouse

Mark B. Meyer, Nancy A. Benkusky, Martin Kaufmann, Seong Min Lee, Robert R. Redfield, Glenville Jones, J. Wesley Pike

J Biol Chem. 2019 Jun 14; 294(24): 9518–9535. Published online 2019 May 3. doi: 10.1074/jbc.RA119.008760

PMCID:: PMC6579472

Abstract Article PDF–1.0M

Select item 65161722.

1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling

Lulu Chen, Renlei Yang, Wanxin Qiao, Wei Zhang, Jie Chen, Li Mao, David Goltzman, Dengshun Miao

Aging Cell. 2019 Jun; 18(3): e12951. Published online 2019 Mar 24. doi: 10.1111/acel.12951

PMCID:: PMC6516172

Abstract Article PDF–1.8M

Select item 52800153.

Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D

Loan Nguyen-Yamamoto, Andrew C. Karaplis, Rene St–Arnaud, David Goltzman

J Am Soc Nephrol. 2017 Feb; 28(2): 586–597. Published online 2016 Aug 17. doi: 10.1681/ASN.2016010066

PMCID:: PMC5280015

Abstract Article

Select item 52491634.

Effects of the Administration of 25(OH) Vitamin D3 in an Experimental Model of Chronic Kidney Disease in Animals Null for 1-Alpha-Hydroxylase

Noelia Torremadé, Milica Bozic, David Goltzman, Elvira Fernandez, José M. Valdivielso

PLoS One. 2017; 12(1): e0170654. Published online 2017 Jan 20. doi: 10.1371/journal.pone.0170654

PMCID:: PMC5249163

Abstract Article PDF–1.0M

Select item 47203935.

1,25(OH)₂D₃ Deficiency Induces Colon Inflammation via Secretion of Senescence-Associated Inflammatory Cytokines

Yun Liu, Lulu Chen, Chunchun Zhi, Ming Shen, Weiwei Sun, Dengshun Miao, Xiaoqin Yuan

PLoS One. 2016; 11(1): e0146426. Published online 2016 Jan 20. doi: 10.1371/journal.pone.0146426

PMCID:: PMC4720393

Abstract Article PDF–13M

Select item 41824506.

Abnormal Calcium Handling and Exaggerated Cardiac Dysfunction in Mice with Defective Vitamin D Signaling

Sangita Choudhury, Soochan Bae, Qingen Ke, Ji Yoo Lee, Sylvia S. Singh, René St-Arnaud, Federica del Monte, Peter M. Kang

PLoS One. 2014; 9(9): e108382. Published online 2014 Sep 30. doi: 10.1371/journal.pone.0108382

PMCID:: PMC4182450

Abstract Article PDF–944K

Select item 37259817.

PTH/PTHrP and Vitamin D Control Antimicrobial Peptide Expression and Susceptibility to Bacterial Skin Infection

Beda Muehleisen, Daniel D. Bikle, Carlos Aguilera, Douglas W. Burton, George L. Sen, Leonard J. Deftos, Richard L. Gallo

Sci Transl Med. Author manuscript; available in PMC 2013 Jul 29.

Published in final edited form as: Sci Transl Med. 2012 May 23; 4(135): 135ra66. doi: 10.1126/scitranslmed.3003759

PMCID:: PMC3725981

Abstract Article PDF–1.1M

Select item 34314298.

Peripubertal Vitamin D₃ Deficiency Delays Puberty and Disrupts the Estrous Cycle in Adult Female Mice

Cary L. Dicken, Davelene D. Israel, Joe B. Davis, Yan Sun, Jun Shu, John Hardin, Genevieve Neal-Perry

Biol Reprod. 2012 Aug; 87(2): 51. Published online 2012 May 9. doi: 10.1095/biolreprod.111.096511

PMCID:: PMC3431429

Abstract Article PDF–2.2M

Select item 30135369.

Comparison of Active Vitamin D Compounds and a Calcimimetic in Mineral Homeostasis

Loan Nguyen-Yamamoto, Isabel Bolivar, Stephen A. Strugnell, David Goltzman

J Am Soc Nephrol. 2010 Oct; 21(10): 1713–1723. doi: 10.1681/ASN.2009050531

PMCID:: PMC3013536

Abstract Article

Select item 258290910.

Altered Endocrine and Autocrine Metabolism of Vitamin D in a Mouse Model of Gastrointestinal Inflammation

Nancy Liu, Lisa Nguyen, Rene F. Chun, Venu Lagishetty, Songyang Ren, Shaoxing Wu, Bruce Hollis, Hector F. DeLuca, John S. Adams, Martin Hewison

Endocrinology. 2008 Oct; 149(10): 4799–4808. Published online 2008 Jun 5. doi: 10.1210/en.2008-0060

PMCID:: PMC2582909

Abstract Article

Select item 255388711.

High Dietary Vitamin D Prevents Hypocalcemia and Osteomalacia in CYP27B1 Knockout Mice

Matthew J. Rowling, Christy Gliniak, JoEllen Welsh, James C. Fleet

J Nutr. Author manuscript; available in PMC 2008 Sep 27.

Published in final edited form as: J Nutr. 2007 Dec; 137(12): 2608–2615. doi: 10.1093/jn/137.12.2608

PMCID:: PMC2553887

Abstract Article PDF–1.1M

Select item 178400312.

Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D–dependent mechanism

Jürgen Schauber, Robert A. Dorschner, Alvin B. Coda, Amanda S. Büchau, Philip T. Liu, David Kiken, Yolanda R. Helfrich, Sewon Kang, Hashem Z. Elalieh, Andreas Steinmeyer, Ulrich Zügel, Daniel D. Bikle, Robert L. Modlin, Richard L. Gallo

J Clin Invest. 2007 Mar 1; 117(3): 803–811. Published online 2007 Feb 8. doi: 10.1172/JCI30142

PMCID:: PMC1784003

Abstract Article PDF–657K

Select item 132500213.

CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D₃-1α-hydroxylase promoter activity in the skin

Janeen L. Vanhooke, Jean M. Prahl, Christine Kimmel-Jehan, Monica Mendelsohn, Eric W. Danielson, Kevin D. Healy, Hector F. DeLuca

Proc Natl Acad Sci U S A. 2006 Jan 3; 103(1): 75–80. Published online 2005 Dec 21. doi: 10.1073/pnas.0509734103

PMCID:: PMC1325002

Abstract Article PDF–464K

Select item 1901214.

Parathyroid hormone activation of the 25-hydroxyvitamin D₃-1α-hydroxylase gene promoter

Holly L. Brenza, Christine Kimmel-Jehan, Frederic Jehan, Toshimasa Shinki, Shu Wakino, Hideharu Anazawa, Tatsuo Suda, Hector F. DeLuca

Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4): 1387–1391. doi: 10.1073/pnas.95.4.1387

PMCID:: PMC19012

Abstract Article PDF–247K

Select item 1054420815.

1,25-Dihydroxyvitamin D₃ regulates furin-mediated FGF23 cleavage

Han Xie, Isinsu Bastepe, Wen Zhou, Birol Ay, Zara Ceraj, Ignacio A. Portales-Castillo, Eva S. Liu, Sherri-Ann M. Burnett-Bowie, Harald Jüppner, Eugene P. Rhee, Murat Bastepe, Petra Simic

JCI Insight. 2023 Sep 8; 8(17): e168957. Published online 2023 Sep 8. doi: 10.1172/jci.insight.168957