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Select item 110041851.

DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells

Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A. Flavell, Zhanju Liu, Mingsong Li, Wen Pan, Shu Zhu

Nat Commun. 2024; 15: 3080. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47235-2

PMCID:: PMC11004185

Article PDF–11M

Select item 105678262.

DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages

Ning Huangfu, Hongchuang Ma, Mengyun Tian, Jie Zhang, Yong Wang, Zhenwei Li, Xiaomin Chen, Hanbin Cui

Inflammation. 2023; 46(5): 1725–1738. Published online 2023 Jun 16. doi: 10.1007/s10753-023-01836-z

PMCID:: PMC10567826

Article PDF–3.5M

Select item 104321483.

Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease

Daniel G. Calame, Tianyu Guo, Chen Wang, Lillian Garrett, Angad Jolly, Moez Dawood, Alina Kurolap, Noa Zunz Henig, Jawid M. Fatih, Isabella Herman, Haowei Du, Tadahiro Mitani, Lore Becker, Birgit Rathkolb, Raffaele Gerlini, Claudia Seisenberger, Susan Marschall, Jill V. Hunter, Amanda Gerard, Alexis Heidlebaugh, Thomas Challman, Rebecca C. Spillmann, Shalini N. Jhangiani, Zeynep Coban-Akdemir, Seema Lalani, Lingxiao Liu, Anya Revah-Politi, Alejandro Iglesias, Edwin Guzman, Evan Baugh, Nathalie Boddaert, Sophie Rondeau, Clothide Ormieres, Giulia Barcia, Queenie K.G. Tan, Isabelle Thiffault, Tomi Pastinen, Kazim Sheikh, Suur Biliciler, Davide Mei, Federico Melani, Vandana Shashi, Yuval Yaron, Mary Steele, Emma Wakeling, Elsebet Østergaard, Lusine Nazaryan-Petersen, Undiagnosed Diseases Network, Francisca Millan, Teresa Santiago-Sim, Julien Thevenon, Ange-Line Bruel, Christel Thauvin-Robinet, Denny Popp, Konrad Platzer, Pawel Gawlinski, Wojciech Wiszniewski, Dana Marafi, Davut Pehlivan, Jennifer E. Posey, Richard A. Gibbs, Valerie Gailus-Durner, Renzo Guerrini, Helmut Fuchs, Martin Hrabě de Angelis, Sabine M. Hölter, Hoi-Hung Cheung, Shen Gu, James R. Lupski

Am J Hum Genet. 2023 Aug 3; 110(8): 1394–1413. Published online 2023 Jul 18. doi: 10.1016/j.ajhg.2023.06.013

PMCID:: PMC10432148

Article PDF–4.2M

Select item 92038514.

Cytosolic Nuclear Sensor Dhx9 Controls Medullary Thymic Epithelial Cell Differentiation by p53-Mediated Pathways

Xue Dong, Jiayu Zhang, Qian Zhang, Zhanfeng Liang, Yanan Xu, Yong Zhao, Baojun Zhang

Front Immunol. 2022; 13: 896472. Published online 2022 Jun 3. doi: 10.3389/fimmu.2022.896472

PMCID:: PMC9203851

Article PDF–7.2M

Select item 88276545.

DExD/H-box helicase 9 intrinsically controls CD8⁺ T cell–mediated antiviral response through noncanonical mechanisms

Anjun Jiao, Chenming Sun, Xin Wang, Lei Lei, Haiyan Liu, Wenhui Li, Xiaofeng Yang, Huiqiang Zheng, Renyi Ding, Kun Zhu, Yanhong Su, Cangang Zhang, Lianjun Zhang, Baojun Zhang

Sci Adv. 2022 Feb; 8(6): eabk2691. Published online 2022 Feb 9. doi: 10.1126/sciadv.abk2691

PMCID:: PMC8827654

Article PDF–6.1M

Select item 50234536.

Tumor Cell Survival Dependence on the DHX9 DExH-Box Helicase

Teresa Lee, Marilène Paquet, Ola Larsson, Jerry Pelletier

Oncogene. Author manuscript; available in PMC 2016 Sep 30.

Published in final edited form as: Oncogene. 2016 Sep 29; 35(39): 5093–5105. Published online 2016 Mar 14. doi: 10.1038/onc.2016.52

PMCID:: PMC5023453

Article PDF–4.7M

Select item 34482907.

Generation of Dhx9 deficient clones in T cell development with a mitotic recombination technique

Yi Zhu, Shiwei Liu, Qili Yin, Tian Xu, Xiaohui Wu, Yuan Zhuang

Genesis. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Genesis. 2012 Jul; 50(7): 543–551. doi: 10.1002/dvg.22005

PMCID:: PMC3448290

Article PDF–1.2M

Select item 108145798.

PARP1, DIDO3, and DHX9 Proteins Mutually Interact in Mouse Fibroblasts, with Effects on DNA Replication Dynamics, Senescence, and Oncogenic Transformation

Agnes Fütterer, Sara Rodriguez-Acebes, Juan Méndez, Julio Gutiérrez, Carlos Martínez-A

Cells. 2024 Jan; 13(2): 159. Published online 2024 Jan 15. doi: 10.3390/cells13020159

PMCID:: PMC10814579

Article PDF–10M

Select item 61586229.

A DNA-sensing–independent role of a nuclear RNA helicase, DHX9, in stimulation of NF-κB–mediated innate immunity against DNA virus infection

Yee Ching Ng, Woo-Chang Chung, Hye-Ri Kang, Hye-Jeong Cho, Eun-Byeol Park, Suk-Jo Kang, Moon Jung Song

Nucleic Acids Res. 2018 Sep 28; 46(17): 9011–9026. Published online 2018 Aug 20. doi: 10.1093/nar/gky742

PMCID:: PMC6158622

Article PDF–5.7M

Select item 989767110.

Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes

Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Mingsong Li, Richard A. Flavell, Shu Zhu

Sci Adv. 2023 Feb; 9(5): eadd5005. Published online 2023 Feb 3. doi: 10.1126/sciadv.add5005

PMCID:: PMC9897671

Article PDF–1.8M

Select item 545817711.

Dependence of p53-deficient cells on the DHX9 DExH-box helicase

Teresa Lee, Jerry Pelletier

Oncotarget. 2017 May 9; 8(19): 30908–30921. Published online 2017 Mar 3. doi: 10.18632/oncotarget.15889

PMCID:: PMC5458177

Article PDF–7.6M

Select item 2488412.

RNA helicase A is essential for normal gastrulation

Chee-Gun Lee, Vera da Costa Soares, Carol Newberger, Katia Manova, Elizabeth Lacy, Jerard Hurwitz

Proc Natl Acad Sci U S A. 1998 Nov 10; 95(23): 13709–13713. doi: 10.1073/pnas.95.23.13709

PMCID:: PMC24884

Article PDF–434K

Select item 1067216613.

Mature mRNA processing that deletes 3′ end sequences directs translational activation and embryonic development

Yuki Takada, Ludivine Fierro, Keisuke Sato, Takahiro Sanada, Anna Ishii, Takehiro Yamamoto, Tomoya Kotani

Sci Adv. 2023 Nov 24; 9(47): eadg6532. Published online 2023 Nov 24. doi: 10.1126/sciadv.adg6532

PMCID:: PMC10672166

Article PDF–2.2M

Select item 358173414.

Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes

Jennifer T. Wolstenholme, Emilie F. Rissman, Stefan Bekiranov

Genes Brain Behav. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Genes Brain Behav. 2013 Mar; 12(2): 166–180. Published online 2013 Jan 10. doi: 10.1111/gbb.12010

PMCID:: PMC3581734

Article PDF–1.5M

Select item 578737515.

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

Shu Zhu, Siyuan Ding, Penghua Wang, Zheng Wei, Wen Pan, Noah W Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Yujiao Zhao, Kellie A. Jurado, Ningguo Feng, Liang Shan, Yuval Kluger, Jun Lu, Clara Abraham, Erol Fikrig, Harry B. Greenberg, Richard A. Flavell

Nature. Author manuscript; available in PMC 2018 Jan 28.

Published in final edited form as: Nature. 2017 Jun 29; 546(7660): 667–670. Published online 2017 Jun 21. doi: 10.1038/nature22967

PMCID:: PMC5787375

Article PDF–1.5M

Select item 350464916.

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs

Rebecca Mathew, Michael P. Seiler, Seth T. Scanlon, Aiping Mao, Michael G. Constantinides, Clara Bertozzi-Villa, Jeffrey D. Singer, Albert Bendelac

Nature. Author manuscript; available in PMC 2013 May 22.

Published in final edited form as: Nature. 2012 Nov 22; 491(7425): 618–621. Published online 2012 Oct 21. doi: 10.1038/nature11548

PMCID:: PMC3504649

Article PDF–1.3M

Select item 266206317.

Analysis of HSF4 Binding Regions Reveals Its Necessity for Gene Regulation during Development and Heat Shock Response in Mouse Lenses

Mitsuaki Fujimoto, Koji Oshima, Toyohide Shinkawa, Bei Bei Wang, Sachiye Inouye, Naoki Hayashida, Ryosuke Takii, Akira Nakai

J Biol Chem. 2008 Oct 31; 283(44): 29961–29970. doi: 10.1074/jbc.M804629200

PMCID:: PMC2662063

Article PDF–929K

Select item 492482618.

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Ronghui Li, Qiping Dong, Xinni Yuan, Xin Zeng, Yu Gao, Cassandra Chiao, Hongda Li, Xinyu Zhao, Sunduz Keles, Zefeng Wang, Qiang Chang

PLoS Genet. 2016 Jun; 12(6): e1006129. Published online 2016 Jun 28. doi: 10.1371/journal.pgen.1006129

PMCID:: PMC4924826

Article PDF–1.9M

Select item 467046019.

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network

Paul A Cassar, Richard L Carpenedo, Payman Samavarchi‐Tehrani, Jonathan B Olsen, Chang Jun Park, Wing Y Chang, Zhaoyi Chen, Chandarong Choey, Sean Delaney, Huishan Guo, Hongbo Guo, R Matthew Tanner, Theodore J Perkins, Scott A Tenenbaum, Andrew Emili, Jeffrey L Wrana, Derrick Gibbings, William L Stanford

EMBO Rep. 2015 Oct; 16(10): 1334–1357. Published online 2015 Aug 11. doi: 10.15252/embr.201540974

PMCID:: PMC4670460

Article PDF–1.9M

Select item 259337120.

Nucleophosmin Serves as a Rate-Limiting Nuclear Export Chaperone for the Mammalian Ribosome

Leonard B. Maggi, Jr., Michael Kuchenruether, David Y. A. Dadey, Rachel M. Schwope, Silvia Grisendi, R. Reid Townsend, Pier Paolo Pandolfi, Jason D. Weber

Mol Cell Biol. 2008 Dec; 28(23): 7050–7065. Published online 2008 Sep 22. doi: 10.1128/MCB.01548-07

PMCID:: PMC2593371

Article PDF–2.0M

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