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Select item 87427651.

A FZD7-specific Antibody–Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models

Myan Do, Christina C.N. Wu, Pooja R. Sonavane, Edwin F. Juarez, Stephen R. Adams, Jason Ross, Alessandra Rodriguez y Baena, Charmi Patel, Jill P. Mesirov, Dennis A. Carson, Sunil J. Advani, Karl Willert

Mol Cancer Ther. 2022 Jan 1; 21(1): 113–124. Published online 2021 Oct 19. doi: 10.1158/1535-7163.MCT-21-0548

PMCID:: PMC8742765

Abstract Article PDF–1.3M

Select item 59464582.

Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

Faye McLeod, Alessandro Bossio, Aude Marzo, Lorenza Ciani, Sara Sibilla, Saad Hannan, Gemma A. Wilson, Ernest Palomer, Trevor G. Smart, Alasdair Gibb, Patricia C. Salinas

Cell Rep. 2018 Apr 24; 23(4): 1060–1071. Published online 2018 Apr 25. doi: 10.1016/j.celrep.2018.03.119

PMCID:: PMC5946458

Abstract Article

Select item 101128973.

Frizzled 7 modulates goblet and Paneth cell fate, and maintains homeostasis in mouse intestine

Nai-Xin Gu, Yu-Ru Guo, Sey-En Lin, Yen-Hsin Wang, I.-Hsuan Lin, Yi-Fan Chen, Yun Yen

Development. 2023 Feb 15; 150(4): dev200932. Published online 2023 Feb 14. doi: 10.1242/dev.200932

PMCID:: PMC10112897

Abstract Article

Select item 64337214.

MicroRNA‐488 inhibits endometrial glandular epithelial cell proliferation, migration, and invasion in endometriosis mice via Wnt by inhibiting FZD7

Hui Zhu, Xi‐Xia Cao, Juan Liu, Hua Hua

J Cell Mol Med. 2019 Apr; 23(4): 2419–2430. Published online 2019 Feb 7. doi: 10.1111/jcmm.14078

PMCID:: PMC6433721

Abstract Article PDF–1.2M

Select item 75755935.

WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

Irene Rodriguez-Hernandez, Oscar Maiques, Leonie Kohlhammer, Gaia Cantelli, Anna Perdrix-Rosell, Joanne Monger, Bruce Fanshawe, Victoria L. Bridgeman, Sophia N. Karagiannis, Rosa M. Penin, Joaquim Marcolval, Rosa M. Marti, Xavier Matias-Guiu, Gilbert O. Fruhwirth, Jose L. Orgaz, Ilaria Malanchi, Victoria Sanz-Moreno

Nat Commun. 2020; 11: 5315. Published online 2020 Oct 20. doi: 10.1038/s41467-020-18951-2

PMCID:: PMC7575593

Abstract Article PDF–6.7M

Select item 55600646.

Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo

Dustin J. Flanagan, Nick Barker, Cameron Nowell, Hans Clevers, Matthias Ernst, Toby J. Phesse, Elizabeth Vincan

Dis Model Mech. 2017 Aug 1; 10(8): 971–980. doi: 10.1242/dmm.029876

PMCID:: PMC5560064

Abstract Article

Select item 44374837.

Frizzled7 Functions as a Wnt Receptor in Intestinal Epithelial Lgr5⁺ Stem Cells

Dustin J. Flanagan, Toby J. Phesse, Nick Barker, Renate H.M. Schwab, Nancy Amin, Jordane Malaterre, Daniel E. Stange, Cameron J. Nowell, Scott A. Currie, Jarel T.S. Saw, Eva Beuchert, Robert G. Ramsay, Owen J. Sansom, Matthias Ernst, Hans Clevers, Elizabeth Vincan

Stem Cell Reports. 2015 May 12; 4(5): 759–767. Published online 2015 Apr 16. doi: 10.1016/j.stemcr.2015.03.003

PMCID:: PMC4437483

Abstract Article PDF–2.7M

Select item 44068448.

MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization

Yusuke Takahashi, Qian Chen, Raju V. S. Rajala, Jian-xing Ma

FEBS Lett. Author manuscript; available in PMC 2016 Apr 28.

Published in final edited form as: FEBS Lett. 2015 Apr 28; 589(10): 1143–1149. Published online 2015 Mar 18. doi: 10.1016/j.febslet.2015.03.010

PMCID:: PMC4406844

Abstract Article PDF–711K

Select item 79116719.

Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs

Yongkyu Park, Midori Lofton, Diana Li, Mladen-Roko Rasin

Cells. 2021 Feb; 10(2): 253. Published online 2021 Jan 28. doi: 10.3390/cells10020253

PMCID:: PMC7911671

Abstract Article PDF–5.1M

Select item 327118110.

Wnt7a/Fzd7 Signalling Directly Activates the Akt/mTOR Anabolic Growth Pathway in Skeletal Muscle

Julia von Maltzahn, C. Florian Bentzinger, Michael A Rudnicki

Nat Cell Biol. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Nat Cell Biol. 2012 Feb; 14(2): 186–191. Published online 2011 Dec 18. doi: 10.1038/ncb2404

PMCID:: PMC3271181

Abstract Article PDF–1.1M

Select item 289755111.

Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization

Michiru Nishita, Sumiyo Itsukushima, Akira Nomachi, Mitsuharu Endo, ZhiChao Wang, Daisuke Inaba, Sen Qiao, Shinji Takada, Akira Kikuchi, Yasuhiro Minami

Mol Cell Biol. 2010 Jul; 30(14): 3610–3619. Published online 2010 May 10. doi: 10.1128/MCB.00177-10

PMCID:: PMC2897551

Abstract Article PDF–2.2M

Select item 398713412.

Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength

C. Florian Bentzinger, Julia von Maltzahn, Nicolas A. Dumont, Danny A. Stark, Yu Xin Wang, Kevin Nhan, Jérôme Frenette, DDW Cornelison, Michael A. Rudnicki

J Cell Biol. 2014 Apr 14; 205(1): 97–111. doi: 10.1083/jcb.201310035

PMCID:: PMC3987134

Abstract Article PDF–4.1M

Select item 1007300813.

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways

Xuming Zhu, Mingang Xu, N. Adrian Leu, Edward E. Morrisey, Sarah E. Millar

Dis Model Mech. 2023 Mar 1; 16(3): dmm049876. Published online 2023 Mar 24. doi: 10.1242/dmm.049876

PMCID:: PMC10073008

Abstract Article

Select item 350973214.

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes

Huimin Yu, Xin Ye, Nini Guo, Jeremy Nathans

Development. 2012 Dec 1; 139(23): 4383–4394. doi: 10.1242/dev.083352

PMCID:: PMC3509732

Abstract Article

Select item 646134915.

Molecular determinants of WNT9b responsiveness in nephron progenitor cells

Kyle K. Dickinson, Leah C. Hammond, Courtney M. Karner, Nicholas D. Hastie, Thomas J. Carroll, Paul Goodyer

PLoS One. 2019; 14(4): e0215139. Published online 2019 Apr 12. doi: 10.1371/journal.pone.0215139

PMCID:: PMC6461349

Abstract Article PDF–2.0M

Select item 202044716.

Essential Roles of Mesenchyme-Derived Beta-Catenin in Mouse Müllerian duct Morphogenesis

Erica Deutscher, Humphrey Hung-Chang Yao

Dev Biol. Author manuscript; available in PMC 2008 Jul 15.

Published in final edited form as: Dev Biol. 2007 Jul 15; 307(2): 227–236. Published online 2007 May 3. doi: 10.1016/j.ydbio.2007.04.036

PMCID:: PMC2020447

Abstract Article PDF–2.0M

Select item 114058517.

Wnt7b Activates Canonical Signaling in Epithelial and Vascular Smooth Muscle Cells through Interactions with Fzd1, Fzd10, and LRP5

Zhishan Wang, Weiguo Shu, Min Min Lu, Edward E. Morrisey

Mol Cell Biol. 2005 Jun; 25(12): 5022–5030. doi: 10.1128/MCB.25.12.5022-5030.2005

PMCID:: PMC1140585

Abstract Article PDF–1001K

Select item 402901618.

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells

Evelyn C. Avilés, Cristina Pinto, Patricia Hanna, Jorge Ojeda, Viviana Pérez, Giancarlo V. De Ferrari, Pedro Zamorano, Miguel Albistur, Daniel Sandoval, Juan P. Henríquez

Front Cell Neurosci. 2014; 8: 110. Published online 2014 Apr 17. doi: 10.3389/fncel.2014.00110

PMCID:: PMC4029016

Abstract Article PDF–2.4M

Select item 274338319.

Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

Fabien Le Grand, Andrew E. Jones, Vanessa Seale, Anthony Scimè, Michael A. Rudnicki

Cell Stem Cell. Author manuscript; available in PMC 2009 Dec 5.

Published in final edited form as: Cell Stem Cell. 2009 Jun 5; 4(6): 535–547. doi: 10.1016/j.stem.2009.03.013

PMCID:: PMC2743383

Abstract Article PDF–1.9M

Select item 628131920.

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

Lori L O'Brien, Alexander N Combes, Kieran M Short, Nils O Lindström, Peter H Whitney, Luise A Cullen-McEwen, Adler Ju, Ahmed Abdelhalim, Odyssé Michos, John F Bertram, Ian M Smyth, Melissa H Little, Andrew P McMahon

eLife. 2018; 7: e40392. Published online 2018 Dec 5. doi: 10.7554/eLife.40392