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Select item 97229021.

Particulate matter promotes cancer metastasis through increased HBEGF expression in macrophages

Seung-Ho Park, Sung-Jin Yoon, Song Choi, Jaeeun Jung, Jun-Young Park, Young-Ho Park, Jinho Seo, Jungwoon Lee, Moo-Seung Lee, Seon-Jin Lee, Mi-Young Son, Young-Lai Cho, Jang-Seong Kim, Hyo Jin Lee, Jinyoung Jeong, Dae-Soo Kim, Young-Jun Park

Exp Mol Med. 2022 Nov; 54(11): 1901–1912. Published online 2022 Nov 9. doi: 10.1038/s12276-022-00886-x

PMCID:: PMC9722902

Abstract Article PDF–5.6M

Select item 69150152.

HB-EGF Ameliorates Oxidative Stress-Mediated Uterine Decidualization Damage

Hai-Fan Yu, Cui-Cui Duan, Zhan-Qing Yang, Yu-Si Wang, Zhan-Peng Yue, Bin Guo

Oxid Med Cell Longev. 2019; 2019: 6170936. Published online 2019 Dec 2. doi: 10.1155/2019/6170936

PMCID:: PMC6915015

Abstract Article PDF–2.2M

Select item 54444913.

Functional Outcomes of Heparin-Binding Epidermal Growth Factor-Like Growth Factor for Regeneration of Chronic Tympanic Membrane Perforations in Mice

Peter Luke Santa Maria, Peter Gottlieb, Chloe Santa Maria, Sungwoo Kim, Sunil Puria, Yunzhi Peter Yang

Tissue Eng Part A. 2017 May 1; 23(9-10): 436–444. Published online 2017 May 1. doi: 10.1089/ten.tea.2016.0395

PMCID:: PMC5444491

Abstract Article PDF–492K

Select item 51422384.

Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion

Fenghua Zeng, Lance A. Kloepfer, Charlene Finney, André Diedrich, Raymond C. Harris

Am J Physiol Renal Physiol. 2016 Oct 1; 311(4): F695–F707. Published online 2016 May 25. doi: 10.1152/ajprenal.00377.2015

PMCID:: PMC5142238

Abstract Article

Select item 44725275.

Heparin-Binding EGF-like Growth Factor and Enteric Neural Stem Cell Transplantation in the Prevention of Experimental Necrotizing Enterocolitis

Jia Wei, Yu Zhou, Gail E. Besner

Pediatr Res. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Pediatr Res. 2015 Jul; 78(1): 29–37. Published online 2015 Mar 25. doi: 10.1038/pr.2015.63

PMCID:: PMC4472527

Abstract Article PDF–1.4M

Select item 35738836.

Heparin-binding epidermal growth factor-like growth factor improves intestinal barrier function and reduces mortality in a murine model of peritonitis

Jixin Yang, Andrei Radulescu, Chun-Liang Chen, Hong-Yi Zhang, Iyore O. James, Gail E. Besner

Surgery. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Surgery. 2013 Jan; 153(1): 52–62. Published online 2012 Jun 15. doi: 10.1016/j.surg.2012.04.002

PMCID:: PMC3573883

Abstract Article PDF–4.2M

Select item 33388737.

Heparin-binding epidermal growth factor-like growth factor suppresses experimental liver fibrosis in mice

Guangcun Huang, Gail E. Besner, David R. Brigstock

Lab Invest. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: Lab Invest. 2012 May; 92(5): 703–712. Published online 2012 Feb 13. doi: 10.1038/labinvest.2012.3

PMCID:: PMC3338873

Abstract Article PDF–2.2M

Select item 30220828.

Mice Overexpressing the Gene for Heparin-Binding EGF-Like Growth Factor (HB-EGF) Have Increased Resistance to Hemorrhagic Shock and Resuscitation

Hong-yi Zhang, Andrei Radulescu, Chun-liang Chen, Jacob K. Olson, Amanda K. Darbyshire, Gail E. Besner

Surgery. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: Surgery. 2011 Feb; 149(2): 276–283. Published online 2010 Oct 20. doi: 10.1016/j.surg.2010.08.003

PMCID:: PMC3022082

Abstract Article PDF–920K

Select item 30082099.

HEPARIN-BINDING EGF-LIKE GROWTH FACTOR PROMOTES INTESTINAL ANASTOMOTIC HEALING

Andrei Radulescu, Hong-Yi Zhang, Chun-Liang Chen, Yan Chen, Yu Zhou, Xiaoyi Yu, Iyore Otabor, Jacob K. Olson, Gail E. Besner

J Surg Res. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: J Surg Res. 2011 Dec; 171(2): 540–550. Published online 2010 Sep 8. doi: 10.1016/j.jss.2010.06.036

PMCID:: PMC3008209

Abstract Article PDF–2.4M

Select item 288674610.

The heparin-binding domain of HB-EGF mediates localization to sites of cell-cell contact and prevents HB-EGF proteolytic release

Robin N. Prince, Eric R. Schreiter, Peng Zou, H. Steven Wiley, Alice Y. Ting, Richard T. Lee, Douglas A. Lauffenburger

J Cell Sci. 2010 Jul 1; 123(13): 2308–2318. Published online 2010 Jun 8. doi: 10.1242/jcs.058321

PMCID:: PMC2886746

Abstract Article

Select item 287254211.

The Expression of Heparin-Binding Epidermal Growth Factor-Like Growth Factor by Regulatory Macrophages

Justin P. Edwards, Xia Zhang, David M. Mosser

J Immunol. Author manuscript; available in PMC 2010 May 18.

Published in final edited form as: J Immunol. 2009 Feb 15; 182(4): 1929–1939. doi: 10.4049/jimmunol.0802703

PMCID:: PMC2872542

Abstract Article PDF–1.0M

Select item 275929012.

Generation and Characterization of Conditional Heparin-Binding EGF-Like Growth Factor Knockout Mice

Atsushi Oyagi, Yasuhisa Oida, Kenichi Kakefuda, Masamitsu Shimazawa, Norifumi Shioda, Shigeki Moriguchi, Kiyoyuki Kitaichi, Daisuke Nanba, Kazumasa Yamaguchi, Yasuhide Furuta, Kohji Fukunaga, Shigeki Higashiyama, Hideaki Hara

PLoS One. 2009; 4(10): e7461. Published online 2009 Oct 14. doi: 10.1371/journal.pone.0007461

PMCID:: PMC2759290

Abstract Article PDF–635K

Select item 249508413.

HB-EGF gene disruption is associated with delayed intestinal restitution, impaired angiogenesis and poor survival after intestinal ischemia in mice

Osama N. El-Assal, Heather Paddock, Alejandro Marquez, Gail E. Besner

J Pediatr Surg. Author manuscript; available in PMC 2009 Jun 1.

Published in final edited form as: J Pediatr Surg. 2008 Jun; 43(6): 1182–1190. doi: 10.1016/j.jpedsurg.2008.02.053

PMCID:: PMC2495084

Abstract Article PDF–682K

Select item 217363714.

Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities

Satoru Yamazaki, Ryo Iwamoto, Kazuko Saeki, Masanori Asakura, Seiji Takashima, Ayano Yamazaki, Rina Kimura, Hiroto Mizushima, Hiroki Moribe, Shigeki Higashiyama, Masayuki Endoh, Yasufumi Kaneda, Satoshi Takagi, Satoshi Itami, Naoki Takeda, Gen Yamada, Eisuke Mekada

J Cell Biol. 2003 Nov 10; 163(3): 469–475. doi: 10.1083/jcb.200307035

PMCID:: PMC2173637

Abstract Article PDF–718K

Select item 1090730015.

The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology

Mathias Linnerbauer, Lena Lößlein, Oliver Vandrey, Anne Peter, Yanan Han, Thanos Tsaktanis, Emile Wogram, Maria Needhamsen, Lara Kular, Lisa Nagel, Julia Zissler, Marie Andert, Lisa Meszaros, Jannis Hanspach, Finnja Zuber, Ulrike J. Naumann, Martin Diebold, Michael A. Wheeler, Tobias Beyer, Lucy Nirschl, Ana Cirac, Frederik B. Laun, Claudia Günther, Jürgen Winkler, Tobias Bäuerle, Maja Jagodic, Bernhard Hemmer, Marco Prinz, Francisco J. Quintana, Veit Rothhammer

Nat Immunol. 2024; 25(3): 432–447. Published online 2024 Feb 26. doi: 10.1038/s41590-024-01756-6

PMCID:: PMC10907300

Abstract Article PDF–22M

Select item 1019397916.

An unanticipated discourse of HB-EGF with VANGL2 signaling during embryo implantation

Yeon Sun Kim, Jia Yuan, Amanda Dewar, Jean-Paul Borg, David W. Threadgill, Xiaofei Sun, Sudhansu K. Dey

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2302937120. Published online 2023 May 8. doi: 10.1073/pnas.2302937120

PMCID:: PMC10193979

Abstract Article PDF–3.3M

Select item 890490217.

HB-EGF Plays a Pivotal Role in Mucosal Hyperplasia During Otitis Media Induced by a Viral Analog

Takashi Sakamoto, Kwang Pak, Eduardo Chavez, Allen F. Ryan, Arwa Kurabi

Front Cell Infect Microbiol. 2022; 12: 823714. Published online 2022 Feb 23. doi: 10.3389/fcimb.2022.823714

PMCID:: PMC8904902

Abstract Article PDF–3.4M

Select item 884285018.

Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation

Lei Zhou, Wenqing Zhou, Ann M. Joseph, Coco Chu, Gregory G. Putzel, Beibei Fang, Fei Teng, Mengze Lv, Hiroshi Yano, Katrin I. Andreasson, Eisuke Mekada, Gerard Eberl, Gregory F. Sonnenberg

Nat Immunol. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Nat Immunol. 2022 Feb; 23(2): 251–261. Published online 2022 Jan 31. doi: 10.1038/s41590-021-01110-0

PMCID:: PMC8842850

Abstract Article PDF–5.4M

Select item 649623119.

Amino‐terminal deletion of heparin‐binding epidermal growth factor‐like growth factor₄₋₁₂₇ stimulates cell proliferation but lacks insulin‐like activity

Z. Zhou, P. A. Harding

Cell Prolif. 2007 Apr; 40(2): 213–230. Published online 2007 Mar 9. doi: 10.1111/j.1365-2184.2007.00425.x

PMCID:: PMC6496231

Abstract Article PDF–494K

Select item 511774420.

Heparin-binding epidermal growth factor-like growth factor and hepatocyte growth factor inhibit cholestatic liver injury in mice through different mechanisms

Kouichi Sakamoto, Ngin Cin Khai, Yuqing Wang, Rie Irie, Hideo Takamatsu, Hiroshi Matsufuji, Ken-Ichiro Kosai

Int J Mol Med. 2016 Dec; 38(6): 1673–1682. Published online 2016 Oct 20. doi: 10.3892/ijmm.2016.2784

PMCID:: PMC5117744

Abstract Article PDF–913K

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