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Select item 91194741.

15-PGDH regulates hematopoietic and gastrointestinal fitness during aging

Won Jin Ho, Julianne N. P. Smith, Young Soo Park, Matthew Hadiono, Kelsey Christo, Alvin Jogasuria, Yongyou Zhang, Alyssia V. Broncano, Lakshmi Kasturi, Dawn M. Dawson, Stanton L. Gerson, Sanford D. Markowitz, Amar B. Desai

PLoS One. 2022; 17(5): e0268787. Published online 2022 May 19. doi: 10.1371/journal.pone.0268787

PMCID:: PMC9119474

Article PDF–1.7M

Select item 73715222.

Inhibition of 15-PGDH Protects Mice from Immune-mediated Bone Marrow Failure

Julianne N.P. Smith, Folashade Otegbeye, Alvin P. Jogasuria, Kelsey F. Christo, Stanton L. Gerson, Sanford Markowitz, Amar B. Desai

Biol Blood Marrow Transplant. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2020 Aug; 26(8): 1552–1556. Published online 2020 May 15. doi: 10.1016/j.bbmt.2020.04.010

PMCID:: PMC7371522

Article PDF–654K

Select item 55476303.

Prostaglandin dehydrogenase is a target for successful induction of cervical ripening

Annavarapu Hari Kishore, Hanquan Liang, Mohammed Kanchwala, Chao Xing, Thota Ganesh, Yucel Akgul, Bruce Posner, Joseph M. Ready, Sanford D. Markowitz, Ruth Ann Word

Proc Natl Acad Sci U S A. 2017 Aug 1; 114(31): E6427–E6436. Published online 2017 Jul 17. doi: 10.1073/pnas.1704945114

PMCID:: PMC5547630

Article PDF–1.9M

Select item 53970674.

15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury

Lu Yao, Weina Chen, Kyoungsub Song, Chang Han, Chandrashekhar R. Gandhi, Kyu Lim, Tong Wu

PLoS One. 2017; 12(4): e0176106. Published online 2017 Apr 19. doi: 10.1371/journal.pone.0176106

PMCID:: PMC5397067

Article PDF–2.6M

Select item 43221895.

Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs

Stephen P. Fink, Dawn M. Dawson, Yongyou Zhang, Adam Kresak, Earl G. Lawrence, Peiying Yang, Yanwen Chen, Jill S. Barnholtz-Sloan, Joseph E. Willis, Levy Kopelovich, Sanford D. Markowitz

Carcinogenesis. 2015 Feb; 36(2): 291–298. Published online 2014 Dec 10. doi: 10.1093/carcin/bgu241

PMCID:: PMC4322189

Article PDF–4.3M

Select item 26950506.

15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors

Min Yan, Seung-Jae Myung, Stephen P. Fink, Earl Lawrence, James Lutterbaugh, Peiying Yang, Xiaohua Zhou, Danielle Liu, Ronald M. Rerko, Joseph Willis, Dawn Dawson, Hsin-Hsiung Tai, Jill S. Barnholtz-Sloan, Robert A. Newman, Monica M. Bertagnolli, Sanford D. Markowitz

Proc Natl Acad Sci U S A. 2009 Jun 9; 106(23): 9409–9413. Published online 2009 May 22. doi: 10.1073/pnas.0902367106

PMCID:: PMC2695050

Article PDF–480K

Select item 44811267.

Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration

Yongyou Zhang, Amar Desai, Sung Yeun Yang, Ki Beom Bae, Monika I. Antczak, Stephen P. Fink, Shruti Tiwari, Joseph E. Willis, Noelle S. Williams, Dawn M. Dawson, David Wald, Wei-Dong Chen, Zhenghe Wang, Lakshmi Kasturi, Gretchen A. Larusch, Lucy He, Fabio Cominelli, Luca Di Martino, Zora Djuric, Ginger L. Milne, Mark Chance, Juan Sanabria, Chris Dealwis, Debra Mikkola, Jacinth Naidoo, Shuguang Wei, Hsin-Hsiung Tai, Stanton L. Gerson, Joseph M. Ready, Bruce Posner, James K. V. Willson, Sanford D. Markowitz

Science. Author manuscript; available in PMC 2015 Dec 12.

Published in final edited form as: Science. 2015 Jun 12; 348(6240): aaa2340. doi: 10.1126/science.aaa2340

PMCID:: PMC4481126

Article PDF–1.3M

Select item 21946298.

Preterm Birth without Progesterone Withdrawal in 15-Hydroxyprostaglandin Dehydrogenase Hypomorphic Mice

Jeffrey D. Roizen, Minoru Asada, Min Tong, Hsin-Hsiung Tai, Louis J. Muglia

Mol Endocrinol. 2008 Jan; 22(1): 105–112. Published online 2007 Sep 13. doi: 10.1210/me.2007-0178

PMCID:: PMC2194629

Article

Select item 94208419.

Smad4-deficient T cells promote colitis-associated colon cancer via an IFN-γ-dependent suppression of 15-hydroxyprostaglandin dehydrogenase

Sung Hee Choi, Alex Y. Huang, John J. Letterio, Byung-Gyu Kim

Front Immunol. 2022; 13: 932412. Published online 2022 Aug 15. doi: 10.3389/fimmu.2022.932412

PMCID:: PMC9420841

Article PDF–14M

Select item 687959710.

Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD^−/−) mice due to requirement for embryo 15-HPGD activity

Jeffrey D. Roizen, Minoru Asada, Min Tong, Hsin-Hsiung Tai, Louis J. Muglia

Sci Rep. 2019; 9: 17612. Published online 2019 Nov 26. doi: 10.1038/s41598-019-54064-7

PMCID:: PMC6879597

Article PDF–1.5M

Select item 373026511.

Preconception Omega-3 Fatty Acid Supplementation of Adult Male Mice with a History of Developmental TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) Exposure Prevents Preterm Birth in Unexposed Female Partners

Melinda E. McConaha, Tianbing Ding, John A. Lucas, Joe A. Arosh, Kevin G. Osteen, Kaylon L. Bruner-Tran

Reproduction. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Reproduction. 2011 Aug; 142(2): 235–241. Published online 2011 Jun 8. doi: 10.1530/REP-11-0070

PMCID:: PMC3730265

Article PDF–2.5M

Select item 290335112.

A Novel Transporter of SLC22 Family Specifically Transports Prostaglandins and Co-localizes with 15-Hydroxyprostaglandin Dehydrogenase in Renal Proximal Tubules

Katsuko Shiraya, Taku Hirata, Ryo Hatano, Shushi Nagamori, Pattama Wiriyasermkul, Promsuk Jutabha, Mitsunobu Matsubara, Shigeaki Muto, Hidekazu Tanaka, Shinji Asano, Naohiko Anzai, Hitoshi Endou, Akira Yamada, Hiroyuki Sakurai, Yoshikatsu Kanai

J Biol Chem. 2010 Jul 16; 285(29): 22141–22151. Published online 2010 May 6. doi: 10.1074/jbc.M109.084426

PMCID:: PMC2903351

Article PDF–1.6M

Select item 184763313.

15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Colorectal Cancer

Michael G. Backlund, Jason R. Mann, Vijaykumar R. Holla, F. Gregory Buchanan, Hsin-Hsiung Tai, Erik S. Musiek, Ginger L. Milne, Sharada Katkuri, Raymond N. DuBois

J Biol Chem. Author manuscript; available in PMC 2007 Apr 4.

Published in final edited form as: J Biol Chem. 2005 Feb 4; 280(5): 3217–3223. Published online 2004 Nov 12. doi: 10.1074/jbc.M411221200

PMCID:: PMC1847633

Article PDF–277K

Select item 156770314.

15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis

Seung-Jae Myung, Ronald M. Rerko, Min Yan, Petra Platzer, Kishore Guda, Angela Dotson, Earl Lawrence, Andrew J. Dannenberg, Alysia Kern Lovgren, Guangbin Luo, Theresa P. Pretlow, Robert A. Newman, Joseph Willis, Dawn Dawson, Sanford D. Markowitz

Proc Natl Acad Sci U S A. 2006 Aug 8; 103(32): 12098–12102. Published online 2006 Jul 31. doi: 10.1073/pnas.0603235103

PMCID:: PMC1567703

Article PDF–1.5M

Select item 722574215.

Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction

Mai Inagaki, Tomohiro Nishimura, Takeo Nakanishi, Hiroaki Shimada, Saki Noguchi, Shin-ichi Akanuma, Masanori Tachikawa, Ken-ichi Hosoya, Ikumi Tamai, Emi Nakashima, Masatoshi Tomi

iScience. 2020 May 22; 23(5): 101098. Published online 2020 Apr 27. doi: 10.1016/j.isci.2020.101098

PMCID:: PMC7225742

Article PDF–3.9M

Select item 836360416.

In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

Kyle D. Duncan, Xiaofei Sun, Erin S. Baker, Sudhansu K. Dey, Ingela Lanekoff

Commun Biol. 2021; 4: 966. Published online 2021 Aug 13. doi: 10.1038/s42003-021-02488-1

Correction in:: Commun Biol. 2021; 4: 1010.

PMCID:: PMC8363604

Article PDF–1.9M

Select item 948197517.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Article

Select item 347934318.

Placental PPARγ Regulates Spatiotemporally Diverse Genes And A Unique Metabolic Network

Tali Shalom-Barak, Xiaowen Zhang, Tianjiao Chu, W. Timothy Schaiff, Janardan K. Reddy, Jianming Xu, Yoel Sadovsky, Yaacov Barak

Dev Biol. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Dev Biol. 2012 Dec 1; 372(1): 143–155. Published online 2012 Aug 29. doi: 10.1016/j.ydbio.2012.08.021

PMCID:: PMC3479343

Article PDF–3.8M

Select item 304626019.

Identification of Anchor Genes during Kidney Development Defines Ontological Relationships, Molecular Subcompartments and Regulatory Pathways

Rathi D. Thiagarajan, Kylie M. Georgas, Bree A. Rumballe, Emmanuelle Lesieur, Han Sheng Chiu, Darrin Taylor, Dave T. P. Tang, Sean M. Grimmond, Melissa H. Little

PLoS One. 2011; 6(2): e17286. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0017286

PMCID:: PMC3046260

Article PDF–982K

Select item 901569920.

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery

Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane

Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054

PMCID:: PMC9015699

Article PDF–3.3M

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