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Select item 63738391.

Ifit1 Protects Against Lipopolysaccharide and D-galactosamine–Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway

Antao Chang, Yanan Chen, Wenzhi Shen, Ruifang Gao, Wei Zhou, Shuang Yang, Yanhua Liu, Yunping Luo, Tsung-Hsien Chuang, Peiqing Sun, Chenghu Liu, Rong Xiang

J Infect Dis. 2015 Nov; 212(9): 1509–1520. Published online 2015 Oct 9. doi: 10.1093/infdis/jiv221

PMCID:: PMC6373839

Abstract Article

Select item 53635232.

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study

Weiping Hu, Guodong Niu, Hongbo Li, Hanyuan Gao, Rudian Kang, Xiaoqing Chen, Ling Lin

Oncotarget. 2016 Nov 22; 7(47): 76464–76470. Published online 2016 Nov 3. doi: 10.18632/oncotarget.13045

PMCID:: PMC5363523

Abstract Article PDF–1.3M

Select item 44157763.

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

Josephine M. Reynaud, Dal Young Kim, Svetlana Atasheva, Aliaksandra Rasalouskaya, James P. White, Michael S. Diamond, Scott C. Weaver, Elena I. Frolova, Ilya Frolov

PLoS Pathog. 2015 Apr; 11(4): e1004863. Published online 2015 Apr 30. doi: 10.1371/journal.ppat.1004863

PMCID:: PMC4415776

Abstract Article PDF–4.0M

Select item 42098994.

A viral RNA structural element alters host recognition of non-self RNA

Jennifer L. Hyde, Christina L. Gardner, Taishi Kimura, James P. White, Gai Liu, Derek W. Trobaugh, Cheng Huang, Marco Tonelli, Slobodan Paessler, Kiyoshi Takeda, William B. Klimstra, Gaya K. Amarasinghe, Michael S. Diamond

Science. Author manuscript; available in PMC 2014 Oct 27.

Published in final edited form as: Science. 2014 Feb 14; 343(6172): 783–787. Published online 2014 Jan 30. doi: 10.1126/science.1248465

PMCID:: PMC4209899

Abstract Article PDF–1.1M

Select item 37540225.

Ifit1 Inhibits Japanese Encephalitis Virus Replication through Binding to 5′ Capped 2′-O Unmethylated RNA

Taishi Kimura, Hiroshi Katoh, Hisako Kayama, Hiroyuki Saiga, Megumi Okuyama, Toru Okamoto, Eiji Umemoto, Yoshiharu Matsuura, Masahiro Yamamoto, Kiyoshi Takeda

J Virol. 2013 Sep; 87(18): 9997–10003. doi: 10.1128/JVI.00883-13

PMCID:: PMC3754022

Abstract Article PDF–548K

Select item 33800006.

Identification and Validation of Ifit1 as an Important Innate Immune Bottleneck

Jason E. McDermott, Keri B. Vartanian, Hugh Mitchell, Susan L. Stevens, Antonio Sanfilippo, Mary P. Stenzel-Poore

PLoS One. 2012; 7(6): e36465. Published online 2012 Jun 20. doi: 10.1371/journal.pone.0036465

PMCID:: PMC3380000

Abstract Article PDF–1.2M

Select item 33497567.

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

Kristy J. Szretter, Brian P. Daniels, Hyelim Cho, Maria D. Gainey, Wayne M. Yokoyama, Michael Gale, Jr., Herbert W. Virgin, Robyn S. Klein, Ganes C. Sen, Michael S. Diamond

PLoS Pathog. 2012 May; 8(5): e1002698. Published online 2012 May 10. doi: 10.1371/journal.ppat.1002698

PMCID:: PMC3349756

Abstract Article PDF–903K

Select item 89735818.

Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) accelerates osteoclast formation by regulating signal transducer and activator of transcription 3 (STAT3) signalling

Yuanliang Xue, Chuanliang Zhao, Tao Liu

Bioengineered. 2022; 13(2): 2285–2295. Published online 2022 Jan 16. doi: 10.1080/21655979.2021.2024333

PMCID:: PMC8973581

Abstract Article PDF–2.3M

Select item 64929239.

IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages

Sinu P. John, Jing Sun, Rebecca J. Carlson, Binh Cao, Clinton J. Bradfield, Jian Song, Margery Smelkinson, Iain D.C. Fraser

Cell Rep. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Cell Rep. 2018 Oct 2; 25(1): 95–106.e6. doi: 10.1016/j.celrep.2018.09.002

PMCID:: PMC6492923

Abstract Article PDF–1.1M

Select item 614713410.

The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins

Christopher M. Weiss, Derek W. Trobaugh, Chengqun Sun, Tiffany M. Lucas, Michael S. Diamond, Kate D. Ryman, William B. Klimstra

mSphere. 2018 Sep-Oct; 3(5): e00209-18. Published online 2018 Sep 19. doi: 10.1128/mSphere.00209-18

PMCID:: PMC6147134

Abstract Article PDF–3.1M

Select item 488720811.

Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals

Matthew D Daugherty, Aaron M Schaller, Adam P Geballe, Harmit S Malik

eLife. 2016; 5: e14228. Published online 2016 May 31. doi: 10.7554/eLife.14228

PMCID:: PMC4887208

Abstract Article PDF–3.1M

Select item 454238212.

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families

Amelia K. Pinto, Graham D. Williams, Kristy J. Szretter, James P. White, José Luiz Proença-Módena, Gai Liu, Judith Olejnik, James D. Brien, Hideki Ebihara, Elke Mühlberger, Gaya Amarasinghe, Michael S. Diamond, Adrianus C. M. Boon

J Virol. 2015 Sep 15; 89(18): 9465–9476. Prepublished online 2015 Jul 8. Published online 2015 Aug 19. doi: 10.1128/JVI.00996-15

PMCID:: PMC4542382

Abstract Article PDF–3.2M

Select item 378975613.

Sequestration by IFIT1 Impairs Translation of 2′O-unmethylated Capped RNA

Matthias Habjan, Philipp Hubel, Livia Lacerda, Christian Benda, Cathleen Holze, Christian H. Eberl, Angelika Mann, Eveline Kindler, Cristina Gil-Cruz, John Ziebuhr, Volker Thiel, Andreas Pichlmair

PLoS Pathog. 2013 Oct; 9(10): e1003663. Published online 2013 Oct 3. doi: 10.1371/journal.ppat.1003663

PMCID:: PMC3789756

Abstract Article PDF–1.4M

Select item 257326614.

Novel Characteristics of the Function and Induction of Murine p56 Family Proteins

Volker Fensterl, Christine L. White, Michifumi Yamashita, Ganes C. Sen

J Virol. 2008 Nov; 82(22): 11045–11053. Published online 2008 Sep 3. doi: 10.1128/JVI.01593-08

PMCID:: PMC2573266

Abstract Article PDF–1.4M

Select item 776295615.

Mouse Ifit1b is a cap1-RNA–binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c

Harriet V. Mears, Trevor R. Sweeney

J Biol Chem. 2020 Dec 18; 295(51): 17781–17801. Published online 2020 Oct 19. doi: 10.1074/jbc.RA120.014695

PMCID:: PMC7762956

Abstract Article PDF–4.9M

Select item 424897916.

Sendai Virus Pathogenesis in Mice Is Prevented by Ifit2 and Exacerbated by Interferon

Jaime L. Wetzel, Volker Fensterl, Ganes C. Sen

J Virol. 2014 Dec; 88(23): 13593–13601. doi: 10.1128/JVI.02201-14

PMCID:: PMC4248979

Abstract Article PDF–1.2M

Select item 417889517.

Interferon-Induced Protein Ifit2 Protects Mice from Infection of the Peripheral Nervous System by Vesicular Stomatitis Virus

Volker Fensterl, Jaime L. Wetzel, Ganes C. Sen

J Virol. 2014 Sep; 88(18): 10303–10311. doi: 10.1128/JVI.01341-14

PMCID:: PMC4178895

Abstract Article PDF–2.7M

Select item 399373618.

Attenuation and Restoration of Severe Acute Respiratory Syndrome Coronavirus Mutant Lacking 2′-O-Methyltransferase Activity

Vineet D. Menachery, Boyd L. Yount, Jr., Laurence Josset, Lisa E. Gralinski, Trevor Scobey, Sudhakar Agnihothram, Michael G. Katze, Ralph S. Baric

J Virol. 2014 Apr; 88(8): 4251–4264. doi: 10.1128/JVI.03571-13

PMCID:: PMC3993736

Abstract Article PDF–5.3M

Select item 195137419.

Tissue-Specific and Inducer-Specific Differential Induction of ISG56 and ISG54 in Mice

Fulvia Terenzi, Christine White, Srabani Pal, Bryan R. G. Williams, Ganes C. Sen

J Virol. 2007 Aug; 81(16): 8656–8665. Published online 2007 Jun 6. doi: 10.1128/JVI.00322-07

PMCID:: PMC1951374

Abstract Article PDF–572K

Select item 179744820.

Coordinated Regulation and Widespread Cellular Expression of Interferon-Stimulated Genes (ISG) ISG-49, ISG-54, and ISG-56 in the Central Nervous System after Infection with Distinct Viruses

Christie Wacher, Marcus Müller, Markus J. Hofer, Daniel R. Getts, Regina Zabaras, Shalina S. Ousman, Fulvia Terenzi, Ganes C. Sen, Nicholas J. C. King, Iain L. Campbell

J Virol. 2007 Jan; 81(2): 860–871. Published online 2006 Nov 1. doi: 10.1128/JVI.01167-06