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Items: 1 to 20 of 47

1.
Deoxycytidine kinase inactivation enhances gemcitabine resistance and sensitizes mitochondrial metabolism interference in pancreatic cancer
Suman Dash, Takeshi Ueda, Akiyoshi Komuro, Masahiko Honda, Ryoichi Sugisawa, Hitoshi Okada
Cell Death Dis. 2024 Feb; 15(2): 131. Published online 2024 Feb 12. doi: 10.1038/s41419-024-06531-x
Correction in:
Cell Death Dis. 2024 May; 15(5): 384.
PMCID:
PMC10861559
AbstractArticlePDF–1.7M
2.
DCK is an Unfavorable Prognostic Biomarker and Correlated With Immune Infiltrates in Liver Cancer
Shu Fang Hu, Xia Lin, Lv Ping Xu, Hong Gang Chen, Ju Feng Guo, Li Jin
Technol Cancer Res Treat. 2020; 19: 1533033820934133. Published online 2020 Jun 26. doi: 10.1177/1533033820934133
PMCID:
PMC7325533
AbstractArticlePDF–617K
3.
dCK Expression and Gene Polymorphism With Gemcitabine Chemosensitivity in Patients With Pancreatic Ductal Adenocarcinoma: A Strobe-Compliant Observational Study
Junjie Xiong, Kiran Altaf, Nengwen Ke, Yichao Wang, Jie Tang, Chunlu Tan, Ang Li, Hao Zhang, Du He, Xubao Liu
Medicine (Baltimore) 2016 Mar; 95(10): e2936. Published online 2016 Mar 11. doi: 10.1097/MD.0000000000002936
PMCID:
PMC4998873
AbstractArticlePDF–643K
4.
Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase
Safiatou T. Coulibaly, Paola Rossolillo, Flore Winter, Franziska K. Kretzschmar, Mélanie Brayé, Darren P. Martin, Daniela Lener, Matteo Negroni
PLoS One. 2015; 10(10): e0140741. Published online 2015 Oct 20. doi: 10.1371/journal.pone.0140741
PMCID:
PMC4618062
AbstractArticlePDF–1.5M
5.
Hypoxia-induced Deoxycytidine Kinase Contributes to Epithelial Proliferation in Pulmonary Fibrosis
Tingting Weng, Jens M. Poth, Harry Karmouty-Quintana, Luis J. Garcia-Morales, Ernestina Melicoff, Fayong Luo, Ning-yuan Chen, Christopher M. Evans, Raquel R. Bunge, Brian A. Bruckner, Matthias Loebe, Kelly A. Volcik, Holger K. Eltzschig, Michael R. Blackburn
Am J Respir Crit Care Med. 2014 Dec 15; 190(12): 1402–1412. Published online 2014 Dec 15. doi: 10.1164/rccm.201404-0744OC
PMCID:
PMC4299646
AbstractArticlePDF–2.1M
6.
Deoxycytidine kinase promotes the migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients
Wei Fan, Zhen-Yuan Zhou, Xin-Fang Huang, Chun-De Bao, Fang Du
Int J Clin Exp Pathol. 2013; 6(12): 2733–2744. Published online 2013 Nov 15.
PMCID:
PMC3843254
AbstractArticlePDF–1.2M
7.
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release
Saugata Hazra, Andrzej Szewczak, Stephan Ort, Manfred Konrad, Arnon Lavie
Biochemistry. Author manuscript; available in PMC 2012 Apr 12.
Published in final edited form as: Biochemistry. 2011 Apr 12; 50(14): 2870–2880. Published online 2011 Mar 16. doi: 10.1021/bi2001032
PMCID:
PMC3071448
AbstractArticlePDF–4.9M
8.
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogs
Saugata Hazra, Stephan Ort, Manfred Konrad, Arnon Lavie
Biochemistry. Author manuscript; available in PMC 2011 Aug 10.
Published in final edited form as: Biochemistry. 2010 Aug 10; 49(31): 6784–6790. doi: 10.1021/bi100839e
PMCID:
PMC2925221
AbstractArticlePDF–564K
9.
Systematic Exploration of Active Site Mutations on Human Deoxycytidine Kinase Substrate Specificity
Pinar Iyidogan, Stefan Lutz
Biochemistry. Author manuscript; available in PMC 2009 Sep 2.
Published in final edited form as: Biochemistry. 2008 Apr 22; 47(16): 4711–4720. Published online 2008 Mar 25. doi: 10.1021/bi800157e
PMCID:
PMC2736870
AbstractArticlePDF–329K
10.
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase
Saugata Hazra, Elisabetta Sabini, Stephan Ort, Manfred Konrad, Arnon Lavie
Biochemistry. Author manuscript; available in PMC 2010 Feb 17.
Published in final edited form as: Biochemistry. 2009 Feb 17; 48(6): 1256–1263. doi: 10.1021/bi802062w
PMCID:
PMC2701478
AbstractArticlePDF–1.6M
11.
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues
Theresa McSorley, Stephan Ort, Saugata Hazra, Arnon Lavie, Manfred Konrad
FEBS Lett. Author manuscript; available in PMC 2009 Mar 5.
Published in final edited form as: FEBS Lett. 2008 Mar 5; 582(5): 720–724. Published online 2008 Feb 5. doi: 10.1016/j.febslet.2008.01.048
PMCID:
PMC2636680
AbstractArticlePDF–430K
12.
Mechanisms of resistance to 5-aza-2′-deoxycytidine in human cancer cell lines
Taichun Qin, Jaroslav Jelinek, Jiali Si, Jingmin Shu, Jean-Pierre J. Issa
Blood. 2009 Jan 15; 113(3): 659–667. Prepublished online 2008 Oct 17. doi: 10.1182/blood-2008-02-140038
PMCID:
PMC2628372
AbstractArticle
13.
Cloning and expression of human deoxycytidine kinase cDNA.
E G Chottiner, D S Shewach, N S Datta, E Ashcraft, D Gribbin, D Ginsburg, I H Fox, B S Mitchell
Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4): 1531–1535. doi: 10.1073/pnas.88.4.1531
PMCID:
PMC51053
SummaryPage BrowsePDF–1.1M
14.
Genomic structure and chromosomal localization of the human deoxycytidine kinase gene.
J J Song, S Walker, E Chen, E E Johnson, 2nd, J Spychala, T Gribbin, B S Mitchell
Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2): 431–434. doi: 10.1073/pnas.90.2.431
PMCID:
PMC45676
SummaryPage BrowsePDF–1.0M
15.
Human deoxycytidine kinase is located in the cell nucleus
Magnus Johansson, Sophia Brismar, Anna Karlsson
Proc Natl Acad Sci U S A. 1997 Oct 28; 94(22): 11941–11945. doi: 10.1073/pnas.94.22.11941
PMCID:
PMC23663
AbstractArticlePDF–341K
16.
Semi-Automated High-Throughput Substrate Screening Assay for Nucleoside Kinases
Katja F. Hellendahl, Maryke Fehlau, Sebastian Hans, Peter Neubauer, Anke Kurreck
Int J Mol Sci. 2021 Nov; 22(21): 11558. Published online 2021 Oct 26. doi: 10.3390/ijms222111558
PMCID:
PMC8584170
AbstractArticlePDF–4.4M
17.
Human equilibrative nucleoside transporter‐1 and deoxycytidine kinase can predict gemcitabine effectiveness in Egyptian patients with Hepatocellular carcinoma
Fadia Attia, Sara Fathy, Maha Anani, Adel Hassan, Fawzy Attia, Gehan Ibrahim, Mona Elazab
J Clin Lab Anal. 2020 Nov; 34(11): e23457. Published online 2020 Jul 16. doi: 10.1002/jcla.23457
PMCID:
PMC7676182
AbstractArticlePDF–448K
18.
Role of Genetic Polymorphisms of Deoxycytidine Kinase and Cytidine Deaminase to Predict Risk of Death in Children with Acute Myeloid Leukemia
Aurora Medina-Sanson, Arturo Ramírez-Pacheco, Silvia Selene Moreno-Guerrero, Elisa María Dorantes-Acosta, Metzeri Sánchez-Preza, Alfonso Reyes-López
Biomed Res Int. 2015; 2015: 309491. Published online 2015 May 18. doi: 10.1155/2015/309491
PMCID:
PMC4450239
AbstractArticlePDF–798K
19.
dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: A dual-institutional follow-up with the RTOG 9704 trial
Florencia McAllister, Danielle M Pineda, Masaya Jimbo, Shruti Lal, Richard A Burkhart, Jennifer Moughan, Kathryn A Winter, Kotb Abdelmohsen, Myriam Gorospe, Ana de Jesus Acosta, Rachana H Lankapalli, Jordan M Winter, Charles J Yeo, Agnieska K Witkiewicz, Christine A Iacobuzio-Donahue, Daniel Laheru, Jonathan R Brody
Cancer Biol Ther. 2014 Jun 1; 15(6): 688–698. Published online 2014 Mar 11. doi: 10.4161/cbt.28413
PMCID:
PMC4049785
AbstractArticlePDF–1.6M
20.
Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity
Shinjiro Nagai, Kazumasa Takenaka, Deepa Nachagari, Charles Rose, Kali Domoney, Daxi Sun, Alex Sparreboom, John D. Schuetz
Cancer Res. Author manuscript; available in PMC 2012 Dec 27.
Published in final edited form as: Cancer Res. 2011 Mar 1; 71(5): 1781–1791. Published online 2011 Jan 18. doi: 10.1158/0008-5472.CAN-10-1919
PMCID:
PMC3531552
AbstractArticlePDF–2.2M

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