PMC Links for Gene (Select 16337) - PMC

Links from Gene

Items: 1 to 20 of 366

<< First< Prev

Page of 19

Next >Last >>

Select item 108468711.

Differential roles of insulin receptor in adipocyte progenitor cells in mice

Yexian Yuan, Zuoxiao Shi, Shaolei Xiong, Ruoci Hu, Qing Song, Zhenyuan Song, Sang-Ging Ong, Yuwei Jiang

Mol Cell Endocrinol. Author manuscript; available in PMC 2024 Feb 6.

Published in final edited form as: Mol Cell Endocrinol. 2023 Aug 1; 573: 111968. Published online 2023 May 25. doi: 10.1016/j.mce.2023.111968

PMCID:: PMC10846871

Abstract Article PDF–4.1M

Select item 103620232.

Activation of brown adipose tissue by a low-protein diet ameliorates hyperglycemia in a diabetic lipodystrophy mouse model

Marcos David Munoz, Alexa Zamudio, Maximilian McCann, Victoria Gil, Pingwen Xu, Chong Wee Liew

Sci Rep. 2023; 13: 11808. Published online 2023 Jul 21. doi: 10.1038/s41598-023-37482-6

PMCID:: PMC10362023

Abstract Article PDF–5.1M

Select item 102141343.

Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model

Wenqiang Chen, Qian Huang, Ekaterina Katie Lazdon, Antonio Gomes, Marisa Wong, Emily Stephens, Tabitha Grace Royal, Dan Frenkel, Weikang Cai, C. Ronald Kahn

Proc Natl Acad Sci U S A. 2023 May 23; 120(21): e2220684120. Published online 2023 May 15. doi: 10.1073/pnas.2220684120

PMCID:: PMC10214134

Abstract Article PDF–2.0M

Select item 97147824.

Insulin increases sensory nerve density and reflex bronchoconstriction in obese mice

Gina N. Calco, Jessica N. Maung, David B. Jacoby, Allison D. Fryer, Zhenying Nie

JCI Insight. 2022 Oct 24; 7(20): e161898. Published online 2022 Oct 24. doi: 10.1172/jci.insight.161898

PMCID:: PMC9714782

Abstract Article PDF–6.1M

Select item 88546215.

Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists

Margaret Wu, Ester Carballo-Jane, Haihong Zhou, Peter Zafian, Ge Dai, Mindy Liu, Julie Lao, Terri Kelly, Dan Shao, Judith Gorski, Dmitri Pissarnitski, Ahmet Kekec, Ying Chen, Stephen F. Previs, Giovanna Scapin, Yacob Gomez-Llorente, Scott A. Hollingsworth, Lin Yan, Danqing Feng, Pei Huo, Geoffrey Walford, Mark D. Erion, David E. Kelley, Songnian Lin, James Mu

Nat Commun. 2022; 13: 942. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28561-9

Correction in:: Nat Commun. 2024; 15: 688.

PMCID:: PMC8854621

Abstract Article PDF–2.5M

Select item 88269296.

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

Søs Skovsø, Evgeniy Panzhinskiy, Jelena Kolic, Haoning Howard Cen, Derek A. Dionne, Xiao-Qing Dai, Rohit B. Sharma, Lynda Elghazi, Cara E. Ellis, Katharine Faulkner, Stephanie A. M. Marcil, Peter Overby, Nilou Noursadeghi, Daria Hutchinson, Xiaoke Hu, Hong Li, Honey Modi, Jennifer S. Wildi, J. Diego Botezelli, Hye Lim Noh, Sujin Suk, Brian Gablaski, Austin Bautista, Ryekjang Kim, Corentin Cras-Méneur, Stephane Flibotte, Sunita Sinha, Dan S. Luciani, Corey Nislow, Elizabeth J. Rideout, Eric N. Cytrynbaum, Jason K. Kim, Ernesto Bernal-Mizrachi, Laura C. Alonso, Patrick E. MacDonald, James D. Johnson

Nat Commun. 2022; 13: 735. Published online 2022 Feb 8. doi: 10.1038/s41467-022-28039-8

PMCID:: PMC8826929

Abstract Article PDF–7.4M

Select item 83923277.

Severe Hepatic Insulin Resistance Induces Vascular Dysfunction: Improvement by Liver-Specific Insulin Receptor Isoform A Gene Therapy in a Murine Diabetic Model

Almudena Gómez-Hernández, Natalia de las Heras, Andrea R. López-Pastor, Gema García-Gómez, Jorge Infante-Menéndez, Paula González-López, Tamara González-Illanes, Vicente Lahera, Manuel Benito, Óscar Escribano

Cells. 2021 Aug; 10(8): 2035. Published online 2021 Aug 9. doi: 10.3390/cells10082035

PMCID:: PMC8392327

Abstract Article PDF–2.5M

Select item 79348478.

Proximal tubular epithelial insulin receptor mediates high-fat diet–induced kidney injury

Hak Joo Lee, Meenalakshmi M. Mariappan, Luke Norton, Terry Bakewell, Denis Feliers, Sae Byeol Oh, Andrew Donati, Cherubina S. Rubannelsonkumar, Manjeri A. Venkatachalam, Stephen E. Harris, Isabelle Rubera, Michel Tauc, Goutam Ghosh Choudhury, C. Ronald Kahn, Kumar Sharma, Ralph A. DeFronzo, Balakuntalam S. Kasinath

JCI Insight. 2021 Feb 8; 6(3): e143619. Published online 2021 Feb 8. doi: 10.1172/jci.insight.143619

PMCID:: PMC7934847

Abstract Article PDF–3.2M

Select item 75765649.

Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy

Gemma V. Brierley, Hannah Webber, Eerika Rasijeff, Sarah Grocott, Kenneth Siddle, Robert K. Semple

Diabetes. 2020 Nov; 69(11): 2481–2489. Published online 2020 Aug 17. doi: 10.2337/db20-0345

PMCID:: PMC7576564

Abstract Article PDF–1.1M

Select item 726434710.

Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype

John L. Fowlkes, R. Clay Bunn, Evangelia Kalaitzoglou, Phil Ray, Iuliana Popescu, Kathryn M. Thrailkill

Sci Rep. 2020; 10: 8842. Published online 2020 Jun 1. doi: 10.1038/s41598-020-65717-3

PMCID:: PMC7264347

Abstract Article PDF–1.5M

Select item 710529211.

Insulin receptor plays a central role in skin carcinogenesis by regulating cytoskeleton assembly

Galina Weingarten, Aya Ben Yaakov, Erez Dror, Jenny Russ, Thomas M. Magin, C. Ronald Kahn, Efrat Wertheimer

FASEB J. 2019 Feb; 33(2): 2241–2251. Published online 2018 Oct 17. doi: 10.1096/fj.201800847R

PMCID:: PMC7105292

Abstract Article

Select item 708385712.

Insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine

Régine Cabrae, Céline Dubuquoy, Michèle Caüzac, Lucille Morzyglod, Sandra Guilmeau, Bénédicte Noblet, Bruno Fève, Catherine Postic, Anne-Françoise Burnol, Marthe Moldes

Sci Rep. 2020; 10: 5186. Published online 2020 Mar 20. doi: 10.1038/s41598-020-61869-4

PMCID:: PMC7083857

Abstract Article PDF–2.4M

Select item 638937813.

Endogenous insulin signaling in the RPE contributes to the maintenance of rod photoreceptor function in diabetes.

Matthew J. Tarchick, Alecia H. Cutler, Timothy D. Trobenter, Michael R. Kozlowski, Emily R. Makowski, Nicholas Holoman, Jianning Shao, Bailey Shen, Bela Anand-Apte, Ivy S. Samuels

Exp Eye Res. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Exp Eye Res. 2019 Mar; 180: 63–74. Published online 2018 Dec 10. doi: 10.1016/j.exer.2018.11.020

PMCID:: PMC6389378

Abstract Article PDF–2.9M

Select item 614116414.

Renal tubule insulin receptor modestly promotes elevated blood pressure and markedly stimulates glucose reabsorption

Jonathan M. Nizar, Blythe D. Shepard, Vianna T. Vo, Vivek Bhalla

JCI Insight. 2018 Aug 23; 3(16): e95107. Published online 2018 Aug 23. doi: 10.1172/jci.insight.95107

PMCID:: PMC6141164

Abstract Article PDF–1.7M

Select item 604741915.

Endothelial Insulin Receptor Restoration Rescues Vascular Function in Male Insulin Receptor Haploinsufficient Mice

Anshuman Sengupta, Peysh A Patel, Nadira Y Yuldasheva, Romana S Mughal, Stacey Galloway, Hema Viswambharan, Andrew M N Walker, Amir Aziz, Jessica Smith, Noman Ali, Ben N Mercer, Helen Imrie, Piruthivi Sukumar, Stephen B Wheatcroft, Mark T Kearney, Richard M Cubbon

Endocrinology. 2018 Aug; 159(8): 2917–2925. Published online 2018 May 15. doi: 10.1210/en.2018-00215

PMCID:: PMC6047419

Abstract Article

Select item 571580916.

Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

Masa Katic, Adam R. Kennedy, Igor Leykin, Andrew Norris, Aileen McGettrick, Stephane Gesta, Steven J. Russell, Matthias Bluher, Eleftheria Maratos-Flier, C. Ronald Kahn

Aging Cell. Author manuscript; available in PMC 2017 Dec 5.

Published in final edited form as: Aging Cell. 2007 Dec; 6(6): 827–839. doi: 10.1111/j.1474-9726.2007.00346.x

PMCID:: PMC5715809

Abstract Article PDF–1.4M

Select item 563590717.

Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice

Masahiro Konishi, Masaji Sakaguchi, Samuel M. Lockhart, Weikang Cai, Mengyao Ella Li, Erica P. Homan, Christian Rask-Madsen, C. Ronald Kahn

Proc Natl Acad Sci U S A. 2017 Oct 3; 114(40): E8478–E8487. Published online 2017 Sep 18. doi: 10.1073/pnas.1710625114

PMCID:: PMC5635907

Abstract Article PDF–1.8M

Select item 550899118.

GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice

Dan Kawamori, Jun Shirakawa, Chong Wee Liew, Jiang Hu, Tomoaki Morioka, Alokesh Duttaroy, Bryan Burkey, Rohit N. Kulkarni

Diabetologia. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Diabetologia. 2017 Aug; 60(8): 1442–1453. Published online 2017 May 20. doi: 10.1007/s00125-017-4303-6

PMCID:: PMC5508991

Abstract Article PDF–4.9M

Select item 544001919.

Insulin Receptor Signaling in POMC, but Not AgRP, Neurons Controls Adipose Tissue Insulin Action

Andrew C. Shin, Nika Filatova, Claudia Lindtner, Tiffany Chi, Seta Degann, Douglas Oberlin, Christoph Buettner

Diabetes. 2017 Jun; 66(6): 1560–1571. Published online 2017 Apr 6. doi: 10.2337/db16-1238

PMCID:: PMC5440019

Abstract Article PDF–1.5M

Select item 537899720.

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression

Weikang Cai, Masaji Sakaguchi, Andre Kleinridders, Gonzalo Gonzalez-Del Pino, Jonathan M. Dreyfuss, Brian T. O'Neill, Alfred K. Ramirez, Hui Pan, Jonathon N. Winnay, Jeremie Boucher, Michael J. Eck, C. Ronald Kahn

Nat Commun. 2017; 8: 14892. Published online 2017 Mar 27. doi: 10.1038/ncomms14892

PMCID:: PMC5378997

Abstract Article PDF–5.1M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 366

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity