PMC Links for Gene (Select 16653) - PMC

Links from Gene

Items: 1 to 20 of 1601

<< First< Prev

Page of 81

Select item 111597851.

K‐ras oncogene silencing strategy reduces tumor growth and enhances gemcitabine chemotherapy efficacy for pancreatic cancer treatment

Soukaina Réjiba, Séverine Wack, Marc Aprahamian, Amor Hajri

Cancer Sci. 2007 Jul; 98(7): 1128–1136. Published online 2007 May 8. doi: 10.1111/j.1349-7006.2007.00506.x

PMCID:: PMC11159785

Abstract Article PDF–371K

Select item 107622642.

KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo

Arafath K. Najumudeen, Sigrid K. Fey, Laura M. Millett, Catriona A. Ford, Kathryn Gilroy, Nuray Gunduz, Rachel A. Ridgway, Eve Anderson, Douglas Strathdee, William Clark, Colin Nixon, Jennifer P. Morton, Andrew D. Campbell, Owen J. Sansom

Nat Commun. 2024; 15: 100. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44342-4

PMCID:: PMC10762264

Abstract Article PDF–2.6M

Select item 105921433.

Allosteric regulation of switch-II domain controls KRAS oncogenicity

Moon Hee Yang, Timothy H. Tran, Bethany Hunt, Rebecca Agnor, Christian W. Johnson, Bing Shui, Timothy J. Waybright, Jonathan A. Nowak, Andrew G. Stephen, Dhirendra K. Simanshu, Kevin M. Haigis

Cancer Res. Author manuscript; available in PMC 2024 Apr 2.

Published in final edited form as: Cancer Res. 2023 Oct 2; 83(19): 3176–3183. doi: 10.1158/0008-5472.CAN-22-3210

PMCID:: PMC10592143

Abstract Article PDF–2.0M

Select item 105442244.

Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation

Pan-Yu Chen, Benjamin J. Huang, Max Harris, Christopher Boone, Weijie Wang, Heidi Carias, Brian Mesiona, Daniela Mavrici, Amanda C. Kohler, Gideon Bollag, Chao Zhang, Ying Zhang, Kevin Shannon

JCI Insight. 2023 Sep 8; 8(17): e168445. Published online 2023 Sep 8. doi: 10.1172/jci.insight.168445

PMCID:: PMC10544224

Abstract Article PDF–3.0M

Select item 103370995.

Chronic Jetlag Accelerates Pancreatic Neoplasia in Conditional Kras-Mutant Mice

Patrick B Schwartz, Morgan T Walcheck, Manabu Nukaya, Derek M Pavelec, Kristina A Matkowskyj, Sean M Ronnekleiv-Kelly

Chronobiol Int. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Chronobiol Int. 2023 Apr; 40(4): 417–437. Published online 2023 Mar 13. doi: 10.1080/07420528.2023.2186122

PMCID:: PMC10337099

Abstract Article PDF–2.9M

Select item 99927726.

Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein

Kobe Janssen, Filip Claes, Dido Van de Velde, Vanessa L. Wehbi, Bert Houben, Yulia Lampi, Mieke Nys, Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rob van der Kant, Joffre Verniers, Teresa Garcia, Meine Ramakers, Katerina Konstantoulea, Katerina Maragkou, Ramon Duran-Romaña, Mónica Musteanu, Mariano Barbacid, Bernard Scorneaux, Els Beirnaert, Joost Schymkowitz, Frederic Rousseau

Proc Natl Acad Sci U S A. 2023 Feb 28; 120(9): e2214921120. Published online 2023 Feb 22. doi: 10.1073/pnas.2214921120

PMCID:: PMC9992772

Abstract Article PDF–2.0M

Select item 97339467.

Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis

Edoardo Del Poggetto, I-Lin Ho, Chiara Balestrieri, Er-Yen Yen, Shaojun Zhang, Francesca Citron, Rutvi Shah, Denise Corti, Giuseppe R. Diaferia, Chieh-Yuan Li, Sara Loponte, Federica Carbone, Yoku Hayakawa, Giovanni Valenti, Shan Jiang, Luigi Sapio, Hong Jiang, Prasenjit Dey, Sisi Gao, Angela K. Deem, Stefan Rose-John, Wantong Yao, Haoqiang Ying, Andrew D. Rhim, Giannicola Genovese, Timothy P. Heffernan, Anirban Maitra, Timothy C. Wang, Linghua Wang, Giulio F. Draetta, Alessandro Carugo, Gioacchino Natoli, Andrea Viale

Science. Author manuscript; available in PMC 2022 Dec 9.

Published in final edited form as: Science. 2021 Sep 17; 373(6561): eabj0486. Published online 2021 Sep 17. doi: 10.1126/science.abj0486

PMCID:: PMC9733946

Abstract Article PDF–3.6M

Select item 95373688.

TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence

Lei Fang, Dongmei Li, JuanJuan Yin, Hong Pan, Huihui Ye, Joel Bowman, Brian Capaldo, Kathleen Kelly

Cancer Gene Ther. Author manuscript; available in PMC 2022 Oct 24.

Published in final edited form as: Cancer Gene Ther. 2022 Oct; 29(10): 1463–1476. Published online 2022 Apr 7. doi: 10.1038/s41417-022-00454-5

PMCID:: PMC9537368

Abstract Article PDF–1.3M

Select item 94374349.

Aberrant activation of KRAS in mouse theca-interstitial cells results in female infertility

Penghao Sun, Hongliang Wang, Lingyun Liu, Kaimin Guo, Xian Li, Yin Cao, Chemyong Ko, Zi-Jian Lan, Zhenmin Lei

Front Physiol. 2022; 13: 991719. Published online 2022 Aug 19. doi: 10.3389/fphys.2022.991719

PMCID:: PMC9437434

Abstract Article PDF–2.4M

Select item 899851110.

Treatment with Angiotensin-(1-7) Prevents Development of Oral Papilloma Induced in K-ras Transgenic Mice

Carolina Schere-Levy, Melisa Suberbordes, Darío M. Ferri, Marina Ayre, Albana Gattelli, Edith C. Kordon, Ana R. Raimondi, Thomas Walther

Int J Mol Sci. 2022 Apr; 23(7): 3642. Published online 2022 Mar 26. doi: 10.3390/ijms23073642

PMCID:: PMC8998511

Abstract Article PDF–2.8M

Select item 870784211.

KRAS Affects Adipogenic Differentiation by Regulating Autophagy and MAPK Activation in 3T3-L1 and C2C12 Cells

Wenjie Yu, Cheng-Zhen Chen, Yanxia Peng, Ze Li, Yan Gao, Shuang Liang, Bao Yuan, Nam-Hyung Kim, Hao Jiang, Jia-Bao Zhang

Int J Mol Sci. 2021 Dec; 22(24): 13630. Published online 2021 Dec 20. doi: 10.3390/ijms222413630

PMCID:: PMC8707842

Abstract Article PDF–4.1M

Select item 849153912.

Therapeutically reprogrammed nutrient signaling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer

Ran Li, Thomas S.C. Ng, Stephanie J. Wang, Mark Prytyskach, Christopher B. Rodell, Hannes Mikula, Rainer H. Kohler, Michelle A. Garlin, Douglas A. Lauffenburger, Sareh Parangi, Daniela M. Dinulescu, Nabeel Bardeesy, Ralph Weissleder, Miles A. Miller

Nat Nanotechnol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Nat Nanotechnol. 2021 Jul; 16(7): 830–839. Published online 2021 May 6. doi: 10.1038/s41565-021-00897-1

PMCID:: PMC8491539

Abstract Article PDF–3.3M

Select item 848657313.

Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP1

Palanivel Kandasamy, Inti Zlobec, Damian T. Nydegger, Jonai Pujol‐Giménez, Rajesh Bhardwaj, Senji Shirasawa, Toshiyuki Tsunoda, Matthias A. Hediger

Mol Oncol. 2021 Oct; 15(10): 2782–2800. Published online 2021 Jun 18. doi: 10.1002/1878-0261.12999

PMCID:: PMC8486573

Abstract Article PDF–5.0M

Select item 838940914.

Role of Ras in regulation of intestinal epithelial cell homeostasis and crosstalk with Wnt signaling

Takenori Kotani, Noriko Ihara, Saki Okamoto, Jajar Setiawan, Tasuku Konno, Yasuyuki Saito, Yoji Murata, Takashi Matozaki

PLoS One. 2021; 16(8): e0256774. Published online 2021 Aug 26. doi: 10.1371/journal.pone.0256774

PMCID:: PMC8389409

Abstract Article PDF–2.5M

Select item 808891315.

Oncogenic KRAS–expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice

Akiyoshi Kasuga, Takashi Semba, Ryo Sato, Hiroyuki Nobusue, Eiji Sugihara, Hiromasa Takaishi, Takanori Kanai, Hideyuki Saya, Yoshimi Arima

Cancer Sci. 2021 May; 112(5): 1822–1838. Published online 2021 Mar 8. doi: 10.1111/cas.14703

PMCID:: PMC8088913

Abstract Article PDF–4.4M

Select item 795589516.

Kras-deficient T cells attenuate graft-versus-host disease but retain graft-versus-leukemia activity

Lan Luo, Yuhong Chen, Xiao Chen, Yongwei Zheng, Vivian Zhou, Mei Yu, Robert Burns, Wen Zhu, Guoping Fu, Juan C. Felix, Christopher Hartley, Alisa Damnernsawad, Jing Zhang, Renren Wen, Williams R. Drobyski, Chunji Gao, Demin Wang

J Immunol. Author manuscript; available in PMC 2021 Mar 13.

Published in final edited form as: J Immunol. 2020 Dec 15; 205(12): 3480–3490. Published online 2020 Nov 6. doi: 10.4049/jimmunol.2000006

PMCID:: PMC7955895

Abstract Article PDF–1.7M

Select item 780666417.

Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models

Wade R. Gutierrez, Amanda Scherer, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Emily A. Laverty, Grace A. Roughton, Rebecca D. Dodd

Sci Rep. 2021; 11: 1098. Published online 2021 Jan 13. doi: 10.1038/s41598-020-80216-1

PMCID:: PMC7806664

Abstract Article PDF–1.3M

Select item 768355018.

The synergistic tumor growth-inhibitory effect of probiotic Lactobacillus on transgenic mouse model of pancreatic cancer treated with gemcitabine

Shan-Ming Chen, Wee-Wei Chieng, Szu-Wei Huang, Li-Jin Hsu, Ming-Shiou Jan

Sci Rep. 2020; 10: 20319. Published online 2020 Nov 23. doi: 10.1038/s41598-020-77322-5

PMCID:: PMC7683550

Abstract Article PDF–7.9M

Select item 764209719.

An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants

Maria Paz Zafra, Marie J Parsons, Jangkyung Kim, Direna Alonso-Curbelo, Sukanya Goswami, Emma M Schatoff, Teng Han, Alyna Katti, Maria Teresa Calvo Fernandez, John E Wilkinson, Elena Piskounova, Lukas E Dow

Cancer Discov. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Cancer Discov. 2020 Nov; 10(11): 1654–1671. Published online 2020 Aug 12. doi: 10.1158/2159-8290.CD-20-0442

PMCID:: PMC7642097

Abstract Article PDF–2.5M

Select item 759187420.

Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice

Marta Cáceres, Rita Quesada, Mar Iglesias, Francisco X. Real, Maria Villamonte, Jaime Martinez de Villarreal, Mónica Pérez, Ana Andaluz, Xavier Moll, Enrique Berjano, Dimitri Dorcaratto, Patricia Sánchez-Velázquez, Luís Grande, Fernando Burdío

Sci Rep. 2020; 10: 18344. Published online 2020 Oct 27. doi: 10.1038/s41598-020-74947-4

Correction in:: Sci Rep. 2021; 11: 5425.

PMCID:: PMC7591874

Abstract Article PDF–2.7M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 1601

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity