PMC Links for Gene (Select 1671) - PMC

Hiutung Chu, Marzena Pazgier, Grace Jung, Sean-Paul Nuccio, Patricia A. Castillo, Maarten F. de Jong, Maria G. Winter, Sebastian E. Winter, Jan Wehkamp, Bo Shen, Nita H. Salzman, Mark A. Underwood, Renee M. Tsolis, Glenn M. Young, Wuyuan Lu, Robert I. Lehrer, Andreas J. Bäumler, Charles L. Bevins

Science. Author manuscript; available in PMC 2015 Feb 18.

Published in final edited form as: Science. 2012 Jul 27; 337(6093): 477–481. Published online 2012 Jun 21. doi: 10.1126/science.1218831

PMCID:: PMC4332406

Abstract Article PDF–1.1M

Select item 41836314.

Molecular Basis for Self-Assembly of a Human Host-Defense Peptide That Entraps Bacterial Pathogens

Phoom Chairatana, Elizabeth M. Nolan

J Am Chem Soc. 2014 Sep 24; 136(38): 13267–13276. Published online 2014 Aug 26. doi: 10.1021/ja5057906

PMCID:: PMC4183631

Abstract Article PDF–3.5M

Select item 29844305.

Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients

Mariya Y Radeva, Franziska Jahns, Anne Wilhelm, Michael Glei, Utz Settmacher, Karl Otto Greulich, Henning Mothes

BMC Cancer. 2010; 10: 588. Published online 2010 Oct 27. doi: 10.1186/1471-2407-10-588

PMCID:: PMC2984430

Abstract Article PDF–658K

Select item 70250396.

Upregulated Expression of Intestinal Antimicrobial Peptide HD5 Associated with Renal Function in IgA Nephropathy

Shaozhen Feng, Zhong Zhong, Jinjin Fan, Xiaoyan Li, Dianchun Shi, Lanping Jiang

Dis Markers. 2020; 2020: 2078279. Published online 2020 Feb 5. doi: 10.1155/2020/2078279

Correction in:: Dis Markers. 2022; 2022: 9797825.

PMCID:: PMC7025039

Abstract Article PDF–806K

Select item 63975837.

Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments

D. Ehmann, J. Wendler, L. Koeninger, I. S. Larsen, T. Klag, J. Berger, A. Marette, M. Schaller, E. F. Stange, N. P. Malek, B. A. H. Jensen, J. Wehkamp

Proc Natl Acad Sci U S A. 2019 Feb 26; 116(9): 3746–3751. Published online 2019 Feb 11. doi: 10.1073/pnas.1817376116

PMCID:: PMC6397583

Abstract Article PDF–1.1M

Select item 44243888.

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide

B O Schroeder, D Ehmann, J C Precht, P A Castillo, R Küchler, J Berger, M Schaller, E F Stange, J Wehkamp

Mucosal Immunol. 2015 May; 8(3): 661–671. Published online 2014 Nov 5. doi: 10.1038/mi.2014.100

PMCID:: PMC4424388

Abstract Article PDF–2.8M

Select item 31463989.

Human defensins 5 and 6 enhance HIV-1 infectivity through promoting HIV attachment

Aprille Rapista, Jian Ding, Bernadette Benito, Yung-Tai Lo, Matthew B Neiditch, Wuyuan Lu, Theresa L Chang

Retrovirology. 2011; 8: 45. Published online 2011 Jun 14. doi: 10.1186/1742-4690-8-45

PMCID:: PMC3146398

Abstract Article PDF–1.3M

Select item 344865310.

Innate Immunity and Non-Hodgkin’s Lymphoma (NHL) Related Genes in a Nested Case-Control Study for Gastric Cancer Risk

Sue K. Park, Jae Jeong Yang, Sohee Oh, Lisa Y. Cho, Seung Hyun Ma, Aesun Shin, Kwang-Pil Ko, Taesung Park, Keun-Young Yoo, Daehee Kang

PLoS One. 2012; 7(9): e45274. Published online 2012 Sep 21. doi: 10.1371/journal.pone.0045274

PMCID:: PMC3448653

Abstract Article PDF–115K

Select item 53887711.

Antibacterial Activity and Specificity of the Six Human α-Defensins

Bryan Ericksen, Zhibin Wu, Wuyuan Lu, Robert I. Lehrer

Antimicrob Agents Chemother. 2005 Jan; 49(1): 269–275. doi: 10.1128/AAC.49.1.269-275.2005

PMCID:: PMC538877

Abstract Article PDF–158K

Select item 224243412.

Crystal structures of human α-defensins HNP4, HD5, and HD6

Agnieszka Szyk, Zhibin Wu, Kenneth Tucker, De Yang, Wuyuan Lu, Jacek Lubkowski

Protein Sci. 2006 Dec; 15(12): 2749–2760. doi: 10.1110/ps.062336606

PMCID:: PMC2242434

Abstract Article PDF–760K

Select item 408563613.

Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia

Jeannette Simino, Gang Shi, Joshua C. Bis, Daniel I. Chasman, Georg B. Ehret, Xiangjun Gu, Xiuqing Guo, Shih-Jen Hwang, Eric Sijbrands, Albert V. Smith, Germaine C. Verwoert, Jennifer L. Bragg-Gresham, Gemma Cadby, Peng Chen, Ching-Yu Cheng, Tanguy Corre, Rudolf A. de Boer, Anuj Goel, Toby Johnson, Chiea-Chuen Khor, LifeLines Cohort Study, Carla Lluís-Ganella, Jian’an Luan, Leo-Pekka Lyytikäinen, Ilja M. Nolte, Xueling Sim, Siim Sõber, Peter J. van der Most, Niek Verweij, Jing Hua Zhao, Najaf Amin, Eric Boerwinkle, Claude Bouchard, Abbas Dehghan, Gudny Eiriksdottir, Roberto Elosua, Oscar H. Franco, Christian Gieger, Tamara B. Harris, Serge Hercberg, Albert Hofman, Alan L. James, Andrew D. Johnson, Mika Kähönen, Kay-Tee Khaw, Zoltan Kutalik, Martin G. Larson, Lenore J. Launer, Guo Li, Jianjun Liu, Kiang Liu, Alanna C. Morrison, Gerjan Navis, Rick Twee-Hee Ong, George J. Papanicolau, Brenda W. Penninx, Bruce M. Psaty, Leslie J. Raffel, Olli T. Raitakari, Kenneth Rice, Fernando Rivadeneira, Lynda M. Rose, Serena Sanna, Robert A. Scott, David S. Siscovick, Ronald P. Stolk, Andre G. Uitterlinden, Dhananjay Vaidya, Melanie M. van der Klauw, Ramachandran S. Vasan, Eranga Nishanthie Vithana, Uwe Völker, Henry Völzke, Hugh Watkins, Terri L. Young, Tin Aung, Murielle Bochud, Martin Farrall, Catharina A. Hartman, Maris Laan, Edward G. Lakatta, Terho Lehtimäki, Ruth J.F. Loos, Gavin Lucas, Pierre Meneton, Lyle J. Palmer, Rainer Rettig, Harold Snieder, E. Shyong Tai, Yik-Ying Teo, Pim van der Harst, Nicholas J. Wareham, Cisca Wijmenga, Tien Yin Wong, Myriam Fornage, Vilmundur Gudnason, Daniel Levy, Walter Palmas, Paul M. Ridker, Jerome I. Rotter, Cornelia M. van Duijn, Jacqueline C.M. Witteman, Aravinda Chakravarti, Dabeeru C. Rao

Am J Hum Genet. 2014 Jul 3; 95(1): 24–38. doi: 10.1016/j.ajhg.2014.05.010

PMCID:: PMC4085636

Abstract Article PDF–1.2M

Select item 296777014.

Polymorphisms in innate immunity genes and risk of childhood leukemia

Sohee Han, Qing Lan, Ae Kyung Park, Kyoung-Mu Lee, Sue K. Park, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Stephen J. Chanock, Ho Kim, Nathaniel Rothman, Daehee Kang

Hum Immunol. Author manuscript; available in PMC 2010 Nov 2.

Published in final edited form as: Hum Immunol. 2010 Jul; 71(7): 727–730. Published online 2010 May 16. doi: 10.1016/j.humimm.2010.04.004

PMCID:: PMC2967770

Abstract Article PDF–306K

Select item 316916715.

Risk of Meningioma and Common Variation in Genes related to Innate Immunity

Preetha Rajaraman, Alina V. Brenner, Gila Neta, Ruth Pfeiffer, Sophia S. Wang, Meredith Yeager, Gilles Thomas, Howard A. Fine, Martha S. Linet, Nathaniel Rothman, Stephen J. Chanock, Peter D. Inskip

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Sep 7.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5): 1356–1361. Published online 2010 Apr 20. doi: 10.1158/1055-9965.EPI-09-1151

PMCID:: PMC3169167

Abstract Article PDF–61K

Select item 277172316.

Common Variation in Genes Related to Innate Immunity and Risk of Adult Glioma

Preetha Rajaraman, Alina V. Brenner, Mary Ann Butler, Sophia S. Wang, Ruth M. Pfeiffer, Avima M. Ruder, Martha S. Linet, Meredith Yeager, Zhaoming Wang, Nick Orr, Howard A. Fine, Deukwoo Kwon, Gilles Thomas, Nathaniel Rothman, Peter D. Inskip, Stephen J. Chanock

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5): 1651–1658. doi: 10.1158/1055-9965.EPI-08-1041

PMCID:: PMC2771723

Abstract Article PDF–392K

Select item 1003393717.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 1007290618.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 674264619.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 464794120.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

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