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Select item 11570021.

Generation of rac3 Null Mutant Mice: Role of Rac3 in Bcr/Abl-Caused Lymphoblastic Leukemia

Young Jin Cho, Bin Zhang, Vesa Kaartinen, Leena Haataja, Ivan de Curtis, John Groffen, Nora Heisterkamp

Mol Cell Biol. 2005 Jul; 25(13): 5777–5785. doi: 10.1128/MCB.25.13.5777-5785.2005

PMCID:: PMC1157002

Abstract Article PDF–315K

Select item 103001652.

Dispensable role of Rac1 and Rac3 after cochlear hair cell specification

Takashi Nakamura, Hirofumi Sakaguchi, Hiroaki Mohri, Yuzuru Ninoyu, Akihiro Goto, Taro Yamaguchi, Yoshitaka Hishikawa, Michiyuki Matsuda, Naoaki Saito, Takehiko Ueyama

J Mol Med (Berl) 2023; 101(7): 843–854. Published online 2023 May 19. doi: 10.1007/s00109-023-02317-4

PMCID:: PMC10300165

Abstract Article PDF–2.1M

Select item 99577273.

RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells

Fuhui Chen, Sevim B. Gurler, David Novo, Cigdem Selli, Denis G. Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H. Sims, Neil E. Humphreys, Antony Adamson, Andrew Campbell, Owen J. Sansom, Cathy Tournier, Robert B. Clarke, Keith Brennan, Charles H. Streuli, Ahmet Ucar

Oncogene. 2023; 42(9): 679–692. Published online 2023 Jan 5. doi: 10.1038/s41388-022-02574-6

PMCID:: PMC9957727

Abstract Article PDF–2.9M

Select item 94369604.

Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer

Kei-ichi Katayama, Yi Zheng, Norimitsu Inoue

Sci Rep. 2022; 12: 14848. Published online 2022 Sep 1. doi: 10.1038/s41598-022-19252-y

PMCID:: PMC9436960

Abstract Article PDF–8.7M

Select item 84646035.

Negative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis

Victoria Gudiño, Patrizia Cammareri, Caroline V. Billard, Kevin B. Myant

Cell Death Dis. 2021 Oct; 12(10): 873. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04177-7

PMCID:: PMC8464603

Abstract Article PDF–8.7M

Select item 66750906.

Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons

Roberta Pennucci, Irene Gucciardi, Ivan de Curtis

PLoS One. 2019; 14(8): e0220496. Published online 2019 Aug 1. doi: 10.1371/journal.pone.0220496

PMCID:: PMC6675090

Abstract Article PDF–2.3M

Select item 51741317.

Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons

Sira A. Franchi, Veronica Astro, Romina Macco, Diletta Tonoli, Jean-Vianney Barnier, Martina Botta, Ivan de Curtis

Front Cell Neurosci. 2016; 10: 289. Published online 2016 Dec 21. doi: 10.3389/fncel.2016.00289

PMCID:: PMC5174131

Abstract Article PDF–4.0M

Select item 47128098.

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks

Roberta Pennucci, Francesca Talpo, Veronica Astro, Valentina Montinaro, Lorenzo Morè, Marco Cursi, Valerio Castoldi, Sara Chiaretti, Veronica Bianchi, Silvia Marenna, Marco Cambiaghi, Diletta Tonoli, Letizia Leocani, Gerardo Biella, Patrizia D'Adamo, Ivan de Curtis

Cereb Cortex. 2016 Feb; 26(2): 873–890. Published online 2015 Nov 17. doi: 10.1093/cercor/bhv274

PMCID:: PMC4712809

Abstract Article PDF–1.6M

Select item 44320049.

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo

Marioara F. Ciuculescu, Shin-Young Park, Kimberly Canty, Ronald Mathieu, Leslie E. Silberstein, David A. Williams

Blood. 2015 May 14; 125(20): 3105–3113. Prepublished online 2015 Mar 30. doi: 10.1182/blood-2014-10-604892

PMCID:: PMC4432004

Abstract Article

Select item 317678610.

Rac1 and Rac3 GTPases Regulate the Development of Hilar Mossy Cells by Affecting the Migration of Their Precursors to the Hilus

Roberta Pennucci, Stefania Tavano, Diletta Tonoli, Sara Gualdoni, Ivan de Curtis

PLoS One. 2011; 6(9): e24819. Published online 2011 Sep 20. doi: 10.1371/journal.pone.0024819

PMCID:: PMC3176786

Abstract Article PDF–4.4M

Select item 313258911.

Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development

Veronica Basso, Sara Corbetta, Sara Gualdoni, Diletta Tonoli, Pietro Luigi Poliani, Francesca Sanvito, Claudio Doglioni, Anna Mondino, Ivan de Curtis

Eur J Immunol. 2011 May; 41(5): 1410–1419. Published online 2011 Mar 7. doi: 10.1002/eji.201040892

PMCID:: PMC3132589

Abstract Article PDF–452K

Select item 288519412.

The 19-Amino Acid Insertion in the Tumor-associated Splice Isoform Rac1b Confers Specific Binding to p120 Catenin

Lidiya Orlichenko, Rory Geyer, Masahiro Yanagisawa, Davitte Khauv, Evette S. Radisky, Panos Z. Anastasiadis, Derek C. Radisky

J Biol Chem. 2010 Jun 18; 285(25): 19153–19161. Published online 2010 Apr 15. doi: 10.1074/jbc.M109.099382

PMCID:: PMC2885194

Abstract Article PDF–3.1M

Select item 805807113.

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V. Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E. Hall, Mark Agostino, John Cassidy, Colin Nixon, Alex von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen J. Sansom, Kevin B. Myant

Nat Commun. 2021; 12: 2335. Published online 2021 Apr 20. doi: 10.1038/s41467-021-22531-3

PMCID:: PMC8058071

Abstract Article PDF–12M

Select item 571628414.

Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation

Sara K. Donnelly, Ramon Cabrera, Serena P.H. Mao, John R. Christin, Bin Wu, Wenjun Guo, Jose Javier Bravo-Cordero, John S. Condeelis, Jeffrey E. Segall, Louis Hodgson

J Cell Biol. 2017 Dec 4; 216(12): 4331–4349. doi: 10.1083/jcb.201704048

PMCID:: PMC5716284

Abstract Article PDF–2.7M

Select item 338302015.

Signaling and cytoskeletal requirements in erythroblast enucleation

Diamantis G. Konstantinidis, Suvarnamala Pushkaran, James F. Johnson, Jose A. Cancelas, Stefanos Manganaris, Chad E. Harris, David A. Williams, Yi Zheng, Theodosia A. Kalfa

Blood. 2012 Jun 21; 119(25): 6118–6127. Prepublished online 2012 Mar 28. doi: 10.1182/blood-2011-09-379263

PMCID:: PMC3383020

Abstract Article

Select item 326519816.

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development

Steven W. Lane, Serena De Vita, Kylie A. Alexander, Ruchan Karaman, Michael D. Milsom, Adrienne M. Dorrance, Amy Purdon, Leeann Louis, Mary L. Bouxsein, David A. Williams

Blood. 2012 Jan 19; 119(3): 736–744. Prepublished online 2011 Nov 28. doi: 10.1182/blood-2011-07-368753

PMCID:: PMC3265198

Abstract Article

Select item 373350317.

Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer Progression

Melody L. Stallings-Mann, Jens Waldmann, Ying Zhang, Erin Miller, Mona L. Gauthier, Daniel W. Visscher, Gregory P. Downey, Evette S. Radisky, Alan P. Fields, Derek C. Radisky

Sci Transl Med. Author manuscript; available in PMC 2013 Aug 5.

Published in final edited form as: Sci Transl Med. 2012 Jul 11; 4(142): 142ra95. doi: 10.1126/scitranslmed.3004062