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Select item 101609991.

Hypoxia induces downregulation of the tumor-suppressive sST2 in colorectal cancer cells via the HIF–nuclear IL-33–GATA3 pathway

Miho Akimoto, Takao Susa, Noriyuki Okudaira, Nobuko Koshikawa, Harumi Hisaki, Masayoshi Iizuka, Hiroko Okinaga, Keizo Takenaga, Tomoki Okazaki, Mimi Tamamori-Adachi

Proc Natl Acad Sci U S A. 2023 May 2; 120(18): e2218033120. Published online 2023 Apr 24. doi: 10.1073/pnas.2218033120

PMCID:: PMC10160999

Abstract Article PDF–7.2M

Select item 101046022.

ILC2 require cell-intrinsic ST2 signals to promote type 2 immune responses

Patrycja M. Topczewska, Zoe A. Rompe, Manuel O. Jakob, Anton Stamm, Pierre S. Leclère, Alexandra Preußer, Claudia U. Duerr, Linda Marie Laura Thole, Katja Kotsch, David Artis, Christoph S. N. Klose

Front Immunol. 2023; 14: 1130933. Published online 2023 Mar 31. doi: 10.3389/fimmu.2023.1130933

PMCID:: PMC10104602

Abstract Article PDF–4.3M

Select item 90069503.

IL-33/ST2 Axis Protects Against Traumatic Brain Injury Through Enhancing the Function of Regulatory T Cells

Di Xie, Wanying Miao, Fei Xu, Chunling Yuan, Sicheng Li, Chujun Wang, Aditi Junagade, Xiaoming Hu

Front Immunol. 2022; 13: 860772. Published online 2022 Mar 30. doi: 10.3389/fimmu.2022.860772

PMCID:: PMC9006950

Abstract Article PDF–14M

Select item 88394214.

IL‐33/ST2 receptor‐dependent signaling in the development of pulmonary hypertension in Sugen/hypoxia mice

Cynthia S. Indralingam, Alma K. Gutierrez‐Gonzalez, Scott C. Johns, Tzuhan Tsui, Daniel T. Cannon, Mark M. Fuster, Timothy D. Bigby, Patricia A. Jennings, Ellen C. Breen

Physiol Rep. 2022 Feb; 10(3): e15185. Published online 2022 Feb 12. doi: 10.14814/phy2.15185

PMCID:: PMC8839421

Abstract Article PDF–1.2M

Select item 84101195.

Deficiency in ST2 signaling ameliorates RSV-associated pulmonary hypertension

Luan D. Vu, Jordy Saravia, Sridhar Jaligama, Rajshri V. Baboeram Panday, Ryan D. Sullivan, Salvatore Mancarella, Stephania A. Cormier, Dai Kimura

Am J Physiol Heart Circ Physiol. 2021 Aug 1; 321(2): H309–H317. Published online 2021 Jun 25. doi: 10.1152/ajpheart.00018.2021

PMCID:: PMC8410119

Abstract Article

Select item 83004286.

ILC2s Improve Glucose Metabolism Through the Control of Saturated Fatty Acid Absorption Within Visceral Fat

Takuro Okamura, Yoshitaka Hashimoto, Jun Mori, Mihoko Yamaguchi, Saori Majima, Takafumi Senmaru, Emi Ushigome, Naoko Nakanishi, Mai Asano, Masahiro Yamazaki, Hiroshi Takakuwa, Takashi Satoh, Shizuo Akira, Masahide Hamaguchi, Michiaki Fukui

Front Immunol. 2021; 12: 669629. Published online 2021 Jul 9. doi: 10.3389/fimmu.2021.669629

PMCID:: PMC8300428

Abstract Article PDF–13M

Select item 80128117.

Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration

Zhenggang Zhang, Na Zhang, Junyu Shi, Chan Dai, Suo Wu, Mengya Jiao, Xuhuan Tang, Yunfei Liu, Xiaoxiao Li, Yong Xu, Zheng Tan, Feili Gong, Fang Zheng

Front Immunol. 2021; 12: 657803. Published online 2021 Mar 18. doi: 10.3389/fimmu.2021.657803

PMCID:: PMC8012811

Abstract Article PDF–7.4M

Select item 78872558.

The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI

Maria Carmen Asensio-Lopez, Yassine Sassi, Fernando Soler, Maria Josefa Fernandez del Palacio, Domingo Pascual-Figal, Antonio Lax

Sci Rep. 2021; 11: 3915. Published online 2021 Feb 16. doi: 10.1038/s41598-021-82745-9

PMCID:: PMC7887255

Abstract Article PDF–5.7M

Select item 77885149.

The IL-33 Receptor/ST2 acts as a positive regulator of functional mouse bone marrow hematopoietic stem and progenitor cells

Maegan L. Capitano, Brad Griesenauer, Bin Guo, Scott Cooper, Sophie Paczesny, Hal E. Broxmeyer

Blood Cells Mol Dis. 2020 Sep; 84: 102435. doi: 10.1016/j.bcmd.2020.102435

PMCID:: PMC7788514

Abstract Article

Select item 721657910.

Altered behavior in mice overexpressing soluble ST2

Motoshi Kikuchi, Kenkichi Takase, Morisada Hayakawa, Hiroko Hayakawa, Shin-ichi Tominaga, Tsukasa Ohmori

Mol Brain. 2020; 13: 74. Published online 2020 May 11. doi: 10.1186/s13041-020-00606-4

PMCID:: PMC7216579

Abstract Article PDF–1.3M

Select item 711820611.

Expression of IL-33 Receptor Is Significantly Up-Regulated in B Cells During Pregnancy and in the Acute Phase of Preterm Birth in Mice

Natalin Valeff, Lorena Juriol, Florencia Quadrana, Damián Oscar Muzzio, Marek Zygmunt, Maria Florencia Quiroga, María Silvia Ventimiglia, Federico Jensen

Front Immunol. 2020; 11: 446. Published online 2020 Mar 27. doi: 10.3389/fimmu.2020.00446

PMCID:: PMC7118206

Abstract Article PDF–1.3M

Select item 683010612.

Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation

Chia-Jung Kuo, Chun-Ya Chen, Horng-Ren Lo, Chun-Lung Feng, Hui-Yu Wu, Mei-Zi Huang, Tung-Nan Liao, Yu-An Chen, Chih-Ho Lai

Cells. 2019 Oct; 8(10): 1290. Published online 2019 Oct 21. doi: 10.3390/cells8101290

PMCID:: PMC6830106

Abstract Article PDF–2.7M

Select item 671274113.

The interleukin-33 receptor contributes to pulmonary responses to ozone in male mice: role of the microbiome

David I. Kasahara, Jeremy E. Wilkinson, Youngji Cho, Aline P. Cardoso, Curtis Huttenhower, Stephanie A. Shore

Respir Res. 2019; 20: 197. Published online 2019 Aug 27. doi: 10.1186/s12931-019-1168-x

PMCID:: PMC6712741

Abstract Article PDF–2.3M

Select item 648351814.

Rorc restrains the potency of ST2⁺ regulatory T cells in ameliorating intestinal graft-versus-host disease

Jinfeng Yang, Abdulraouf Ramadan, Dawn K. Reichenbach, Michael Loschi, Jilu Zhang, Brad Griesenauer, Hong Liu, Keli L. Hippen, Bruce R Blazar, Sophie Paczesny

JCI Insight. 2019 Mar 7; 4(5): e122014. Published online 2019 Mar 7. doi: 10.1172/jci.insight.122014

PMCID:: PMC6483518

Abstract Article PDF–2.3M

Select item 602679915.

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin

Manoussa Fanny, Mégane Nascimento, Ludivine Baron, Corinne Schricke, Isabelle Maillet, Myriam Akbal, Nicolas Riteau, Marc Le Bert, Valérie Quesniaux, Bernhard Ryffel, Aurélie Gombault, Sandra Même, William Même, Isabelle Couillin

Front Immunol. 2018; 9: 1476. Published online 2018 Jun 25. doi: 10.3389/fimmu.2018.01476

PMCID:: PMC6026799

Abstract Article PDF–5.2M

Select item 586254516.

Transcriptional heterogeneity of mast cells and basophils upon activation

Krishan D. Chhiba, Chia-Lin Hsu, Sergejs Berdnikovs, Paul J. Bryce

J Immunol. Author manuscript; available in PMC 2018 Jun 15.

Published in final edited form as: J Immunol. 2017 Jun 15; 198(12): 4868–4878. Published online 2017 May 5. doi: 10.4049/jimmunol.1601825

PMCID:: PMC5862545

Abstract Article PDF–3.3M

Select item 545748617.

Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity

Gillian Coakley, Jana L. McCaskill, Jessica G. Borger, Fabio Simbari, Elaine Robertson, Marissa Millar, Yvonne Harcus, Henry J. McSorley, Rick M. Maizels, Amy H. Buck

Cell Rep. 2017 May 23; 19(8): 1545–1557. Published online 2017 May 23. doi: 10.1016/j.celrep.2017.05.001

PMCID:: PMC5457486

Abstract Article PDF–3.0M

Select item 534150518.

Functional interleukin‐33 receptors are expressed in early progenitor stages of allergy‐related granulocytes

Hirofumi Tsuzuki, Yojiro Arinobu, Kohta Miyawaki, Ayako Takaki, Shun‐ichiro Ota, Yuri Ota, Hiroki Mitoma, Mitsuteru Akahoshi, Yasuo Mori, Hiromi Iwasaki, Hiroaki Niiro, Hiroshi Tsukamoto, Koichi Akashi

Immunology. 2017 Jan; 150(1): 64–73. Published online 2016 Sep 30. doi: 10.1111/imm.12667

PMCID:: PMC5341505

Abstract Article PDF–414K

Select item 476034319.

The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice

Kirsten D. Mertz, Lukas F. Mager, Marie-Hélène Wasmer, Thore Thiesler, Viktor H. Koelzer, Giulia Ruzzante, Stefanie Joller, Jenna R. Murdoch, Thomas Brümmendorf, Vera Genitsch, Alessandro Lugli, Gieri Cathomas, Holger Moch, Achim Weber, Inti Zlobec, Tobias Junt, Philippe Krebs

Oncoimmunology. 2016; 5(1): e1062966. Published online 2015 Jun 26. doi: 10.1080/2162402X.2015.1062966

PMCID:: PMC4760343

Abstract Article PDF–1.3M

Select item 444911520.

IL-33 attenuates the development of experimental autoimmune uveitis

Mark Barbour, Debbie Allan, Heping Xu, Cheng Pei, Mei Chen, Wanda Niedbala, Sandra Y Fukada, Anne-Galle Besnard, Jose C Alves-Filho, Xiaoguang Tong, John V Forrester, Foo Yew Liew, Hui-Rong Jiang

Eur J Immunol. 2014 Nov; 44(11): 3320–3329. Published online 2014 Oct 18. doi: 10.1002/eji.201444671