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Select item 111940981.

The long non-coding RNA Meg3 mediates imprinted gene expression during stem cell differentiation

Sabina Farhadova, Amani Ghousein, François Charon, Caroline Surcis, Melisa Gomez-Velazques, Clara Roidor, Flavio Di Michele, Maud Borensztein, Albertina De Sario, Cyril Esnault, Daan Noordermeer, Benoit Moindrot, Robert Feil

Nucleic Acids Res. 2024 Jun 24; 52(11): 6183–6200. Published online 2024 Apr 13. doi: 10.1093/nar/gkae247

PMCID:: PMC11194098

Abstract Article PDF–2.5M

Select item 97186832.

Transcriptome and chromatin alterations in social fear indicate association of MEG3 with successful extinction of fear

Melanie Royer, Balagopal Pai, Rohit Menon, Anna Bludau, Katharina Gryksa, Rotem Ben-Tov Perry, Igor Ulitsky, Gunter Meister, Inga D. Neumann

Mol Psychiatry. 2022; 27(10): 4064–4076. Published online 2022 Mar 25. doi: 10.1038/s41380-022-01481-2

PMCID:: PMC9718683

Abstract Article PDF–3.8M

Select item 90579003.

Glucose-6-phosphate dehydrogenase and MEG3 controls hypoxia-induced expression of serum response factor (SRF) and SRF-dependent genes in pulmonary smooth muscle cell

Atsushi Kitagawa, Christina Jacob, Sachin A. Gupte

J Smooth Muscle Res. 2022; 58: 34–49. Published online 2022 Apr 29. doi: 10.1540/jsmr.58.34

PMCID:: PMC9057900

Abstract Article PDF–3.1M

Select item 88100164.

Mechanism of M2 macrophage-derived extracellular vesicles carrying lncRNA MEG3 in inflammatory responses in ulcerative colitis

Yu-Xuan Wang, Cheng Lin, Lu-Jia Cui, Tao-Zhi Deng, Qiu-Min Li, Feng-Ying Chen, Xin-Pu Miao

Bioengineered. 2021; 12(2): 12722–12739. Published online 2021 Dec 11. doi: 10.1080/21655979.2021.2010368

PMCID:: PMC8810016

Abstract Article PDF–4.4M

Select item 82124545.

Long non-coding RNA MEG3 mediates the miR-149-3p/FOXP3 axis by reducing p53 ubiquitination to exert a suppressive effect on regulatory T cell differentiation and immune escape in esophageal cancer

Qi-Rong Xu, Jian Tang, Hong-Ying Liao, Ben-Tong Yu, Xiang-Yuan He, Yu-Zhen Zheng, Sheng Liu

J Transl Med. 2021; 19: 264. Published online 2021 Jun 17. doi: 10.1186/s12967-021-02907-1

PMCID:: PMC8212454

Abstract Article PDF–1.4M

Select item 76869636.

Long non‐coding RNA MEG3 inhibits M2 macrophage polarization by activating TRAF6 via microRNA‐223 down‐regulation in viral myocarditis

Yu‐Long Xue, Sheng‐Xiao Zhang, Chao‐Feng Zheng, Yu‐Feng Li, Li‐Hui Zhang, Qin‐Yi Su, Yu‐Fei Hao, Shu Wang, Xue‐Wen Li

J Cell Mol Med. 2020 Nov; 24(21): 12341–12354. Published online 2020 Oct 13. doi: 10.1111/jcmm.15720

PMCID:: PMC7686963

Abstract Article PDF–1.4M

Select item 76551877.

Silencing of long non-coding RNA MEG3 alleviates lipopolysaccharide-induced acute lung injury by acting as a molecular sponge of microRNA-7b to modulate NLRP3

Handi Liao, Suning Zhang, Jianou Qiao

Aging (Albany NY) 2020 Oct 31; 12(20): 20198–20211. Published online 2020 Aug 27. doi: 10.18632/aging.103752

PMCID:: PMC7655187

Abstract Article PDF–2.0M

Select item 74696848.

Identification of differentially expressed mRNA and the Hub mRNAs modulated by lncRNA Meg3 as a competing endogenous RNA in brown adipose tissue of mice on a high-fat diet

Yemin Zhang, Yalin Fu, Yuyang Zheng, Zhongyuan Wen, Changhua Wang

Adipocyte. 2020; 9(1): 347–359. Published online 2020 Jul 2. doi: 10.1080/21623945.2020.1789283

PMCID:: PMC7469684

Abstract Article PDF–10M

Select item 65947929.

Long non-coding RNA MEG3 promotes fibrosis and inflammatory response in diabetic nephropathy via miR-181a/Egr-1/TLR4 axis

Fangfang Zha, Xiaolu Qu, Bo Tang, Ji Li, Yakun Wang, PengXi Zheng, Tingting Ji, Chun Zhu, Shoujun Bai

Aging (Albany NY) 2019 Jun 15; 11(11): 3716–3730. Published online 2019 Jun 13. doi: 10.18632/aging.102011

PMCID:: PMC6594792

Abstract Article PDF–2.2M

Select item 653348110.

Silencing long non‐coding RNA MEG3 accelerates tibia fraction healing by regulating the Wnt/β‐catenin signalling pathway

Yu‐Bao Liu, Lu‐Pan Lin, Rui Zou, Qing‐Hua Zhao, Fu‐Qing Lin

J Cell Mol Med. 2019 Jun; 23(6): 3855–3866. Published online 2019 Apr 6. doi: 10.1111/jcmm.14229

PMCID:: PMC6533481

Abstract Article PDF–1.4M

Select item 335948811.

Establishment of paternal allele-specific DNA methylation at the imprinted mouse Gtl2 locus

Kamila Nowak, Geneva Stein, Elizabeth Powell, Lu Mei He, Snehal Naik, Jane Morris, Sara Marlow, Tamara L Davis

Epigenetics. 2011 Aug; 6(8): 1012–1020. Published online 2011 Aug 1. doi: 10.4161/epi.6.8.16075

PMCID:: PMC3359488

Abstract Article PDF–1.8M

Select item 292401612.

Restoration of Dlk1 and Rtl1 Is Necessary but Insufficient to Rescue Lethality in Intergenic Differentially Methylated Region (IG-DMR)-deficient Mice

Nozomi Takahashi, Ryota Kobayashi, Tomohiro Kono

J Biol Chem. 2010 Aug 20; 285(34): 26121–26125. Published online 2010 May 28. doi: 10.1074/jbc.M109.075325

PMCID:: PMC2924016

Abstract Article PDF–1.4M

Select item 1124433813.

Transgenerational epigenetic self-memory of Dio3 dosage is associated with Meg3 methylation and altered growth trajectories and neonatal hormones

M. Elena Martinez, Aldona Karaczyn, Zhaofei Wu, Christian A. Bennett, Kassey L. Matoin, Heather M. Daigle, Arturo Hernandez

Epigenetics. 2024; 19(1): 2376948. Published online 2024 Jul 11. doi: 10.1080/15592294.2024.2376948

PMCID:: PMC11244338

Abstract Article PDF–7.0M

Select item 1053204814.

A Lipid Nanoparticle-Based Method for the Generation of Liver-Specific Knockout Mice

Sumiyo Morita, Takuro Horii, Mika Kimura, Ryosuke Kobayashi, Hiroki Tanaka, Hidetaka Akita, Izuho Hatada

Int J Mol Sci. 2023 Sep; 24(18): 14299. Published online 2023 Sep 19. doi: 10.3390/ijms241814299

PMCID:: PMC10532048

Abstract Article PDF–1.1M

Select item 1028667915.

Inhibition of MEG3 ameliorates cardiomyocyte apoptosis and autophagy by regulating the expression of miRNA-129-5p in a mouse model of heart failure

Shan Mi, Feng Huang, Mingli Jiao, Zhuang Qian, Mingming Han, Zheng Miao, Heqin Zhan

Redox Rep. 2023; 28(1): 2224607. Published online 2023 Jun 20. doi: 10.1080/13510002.2023.2224607

PMCID:: PMC10286679

Abstract Article PDF–4.1M

Select item 997769016.

The long noncoding RNA Meg3 mediates TLR4-induced inflammation in experimental obstructive nephropathy

Wai Han Yiu, Sarah W.Y. Lok, Rui Xue, Jiaoyi Chen, Kar Neng Lai, Hui Yao Lan, Sydney C.W. Tang

Clin Sci (Lond) 2023 Mar; 137(5): 317–331. Published online 2023 Mar 1. doi: 10.1042/CS20220537

PMCID:: PMC9977690

Abstract Article PDF–16M

Select item 916197717.

Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis

Jia Li, Junbo Bai, Nafeisha Tuerdi, Kaifang Liu

Bioengineered. 2022; 13(4): 8676–8688. Published online 2022 Mar 24. doi: 10.1080/21655979.2022.2054501

PMCID:: PMC9161977

Abstract Article PDF–2.4M

Select item 789254018.

c-MYC-induced long noncoding RNA MEG3 aggravates kidney ischemia–reperfusion injury through activating mitophagy by upregulation of RTKN to trigger the Wnt/β-catenin pathway

Dajun Liu, Ying Liu, Xiaotong Zheng, Naiquan Liu

Cell Death Dis. 2021 Feb; 12(2): 191. Published online 2021 Feb 18. doi: 10.1038/s41419-021-03466-5

PMCID:: PMC7892540

Abstract Article PDF–4.2M

Select item 784413119.

Long non-coding RNA Meg3 deficiency impairs glucose homeostasis and insulin signaling by inducing cellular senescence of hepatic endothelium in obesity

Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Matthew Moran, Martonio Ponte Viana, Sarah L. Schlichte, Matthew C. Zimmerman, Oleh Khalimonchuk, Mark W. Feinberg, Xinghui Sun

Redox Biol. 2021 Apr; 40: 101863. Published online 2021 Jan 19. doi: 10.1016/j.redox.2021.101863