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Select item 99501921.

DNMT2/TRDMT1 gene knockout compromises doxorubicin-induced unfolded protein response and sensitizes cancer cells to ER stress-induced apoptosis

Jagoda Adamczyk-Grochala, Dominika Bloniarz, Klaudia Zielinska, Anna Lewinska, Maciej Wnuk

Apoptosis. 2023; 28(1-2): 166–185. Published online 2022 Oct 23. doi: 10.1007/s10495-022-01779-0

PMCID:: PMC9950192

Abstract Article PDF–8.1M

Select item 86827882.

Position 34 of tRNA is a discriminative element for m⁵C38 modification by human DNMT2

Zhi-Xuan Huang, Jing Li, Qing-Ping Xiong, Hao Li, En-Duo Wang, Ru-Juan Liu

Nucleic Acids Res. 2021 Dec 16; 49(22): 13045–13061. Published online 2021 Dec 6. doi: 10.1093/nar/gkab1148

PMCID:: PMC8682788

Abstract Article PDF–4.1M

Select item 82663553.

The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence

Dominika Bloniarz, Jagoda Adamczyk-Grochala, Anna Lewinska, Maciej Wnuk

Aging (Albany NY) 2021 Jun 30; 13(12): 15833–15874. Published online 2021 Jun 17. doi: 10.18632/aging.203203

PMCID:: PMC8266355

Abstract Article PDF–9.1M

Select item 82213454.

TRDMT1 participates in the DNA damage repair of granulosa cells in premature ovarian failure

Chunli Sha, Lu Chen, Li Lin, Taoqiong Li, Hong Wei, Meiling Yang, Wujiang Gao, Dan Zhao, Qi Chen, Yueqin Liu, Xiaofang Chen, Wenlin Xu, Yuefeng Li, Xiaolan Zhu

Aging (Albany NY) 2021 Jun 15; 13(11): 15193–15213. Published online 2021 Jun 8. doi: 10.18632/aging.203080

PMCID:: PMC8221345

Abstract Article PDF–3.3M

Select item 77271165.

Trdmt1 3'-untranslated region functions as a competing endogenous RNA in leukemia HL-60 cell differentiation

Sha Xu, Jun Xiong, Minjuan Wu, Yu Yang, Junfeng Jiang, Haitao Ni, Yunpeng Zhao, Yue Wang

Braz J Med Biol Res. 2021; 54(2): e9869. Published online 2020 Dec 9. doi: 10.1590/1414-431X20209869

PMCID:: PMC7727116

Abstract Article PDF–669K

Select item 1525726.

Endogenous Assays of DNA Methyltransferases: Evidence for Differential Activities of DNMT1, DNMT2, and DNMT3 in Mammalian Cells In Vivo

Kui Liu, Yun Fei Wang, Carmen Cantemir, Mark T. Muller

Mol Cell Biol. 2003 Apr; 23(8): 2709–2719. doi: 10.1128/MCB.23.8.2709-2719.2003

PMCID:: PMC152572

Abstract Article PDF–418K

Select item 80463017.

Decoding the Genetic Alterations in Genes of DNMT Family (DNA Methyl-Transferase) and their Association with Head and Neck Squamous Cell Carcinoma

Tahreem Fathima, Paramasivam Arumugam, Smiline Girija AS, J Vijayashree Priyadharsini

Asian Pac J Cancer Prev. 2020 Dec; 21(12): 3605–3612. doi: 10.31557/APJCP.2020.21.12.3605

PMCID:: PMC8046301

Abstract Article PDF–740K

Select item 24914818.

Human DNMT2 methylates tRNA^Asp molecules using a DNA methyltransferase-like catalytic mechanism

Tomasz P. Jurkowski, Madeleine Meusburger, Sameer Phalke, Mark Helm, Wolfgang Nellen, Gunter Reuter, Albert Jeltsch

RNA. 2008 Aug; 14(8): 1663–1670. doi: 10.1261/rna.970408

PMCID:: PMC2491481

Abstract Article PDF–783K

Select item 1475989.

Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells.

M Okano, S Xie, E Li

Nucleic Acids Res. 1998 Jun 1; 26(11): 2536–2540. doi: 10.1093/nar/26.11.2536

PMCID:: PMC147598

Summary PDF–244K

Select item 2966010.

Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA

Aiping Dong, Jeffrey A. Yoder, Xing Zhang, Lan Zhou, Timothy H. Bestor, Xiaodong Cheng

Nucleic Acids Res. 2001 Jan 15; 29(2): 439–448. doi: 10.1093/nar/29.2.439

PMCID:: PMC29660

Abstract Article PDF–916K

Select item 343023911.

Risk-Association of DNA Methyltransferases Polymorphisms with Gastric Cancer in the Southern Chinese Population

Xue-Xi Yang, Xuan-Qiu He, Fen-Xia Li, Ying-Song Wu, Yang Gao, Ming Li

Int J Mol Sci. 2012; 13(7): 8364–8378. Published online 2012 Jul 5. doi: 10.3390/ijms13078364

PMCID:: PMC3430239

Abstract Article PDF–148K

Select item 286377912.

Hepatitis B Virus Replication Induces Methylation of both Host and Viral DNA

Perumal Vivekanandan, Hubert Darius-J Daniel, Rajesh Kannangai, Francisco Martinez-Murillo, Michael Torbenson

J Virol. 2010 May; 84(9): 4321–4329. Published online 2010 Feb 10. doi: 10.1128/JVI.02280-09

PMCID:: PMC2863779

Abstract Article PDF–1.2M

Select item 653640913.

Suppression of long non‐coding RNA TNRC6C‐AS1 protects against thyroid carcinoma through DNA demethylation of STK4 via the Hippo signalling pathway

Liu‐Xue Yang, Ji Wu, Man‐Li Guo, Yong Zhang, Shao‐Gang Ma

Cell Prolif. 2019 May; 52(3): e12564. Published online 2019 Apr 1. doi: 10.1111/cpr.12564

PMCID:: PMC6536409

Abstract Article PDF–1.6M

Select item 236029714.

Prognostic significance of folate metabolism polymorphisms for lung cancer

A Matakidou, R el Galta, M F Rudd, E L Webb, H Bridle, T Eisen, R S Houlston, and the GELCAPS Consortium

Br J Cancer. 2007 Jul 16; 97(2): 247–252. Published online 2007 May 29. doi: 10.1038/sj.bjc.6603830

PMCID:: PMC2360297

Abstract Article PDF–123K

Select item 389456715.

Genome wide association and linkage analyses identified three loci—4q25, 17q23.2, and 10q11.21—associated with variation in leukocyte telomere length: the Long Life Family Study

Joseph H. Lee, Rong Cheng, Lawrence S. Honig, Mary Feitosa, Candace M. Kammerer, Min S. Kang, Nicole Schupf, Shiow J. Lin, Jason L. Sanders, Harold Bae, Todd Druley, Thomas Perls, Kaare Christensen, Michael Province, Richard Mayeux

Front Genet. 2013; 4: 310. Published online 2014 Jan 17. doi: 10.3389/fgene.2013.00310

PMCID:: PMC3894567

Abstract Article PDF–960K

Select item 432122716.

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

Joyce BJ van Meurs, Guillaume Pare, Stephen M Schwartz, Aditi Hazra, Toshiko Tanaka, Sita H Vermeulen, Ioana Cotlarciuc, Xin Yuan, Anders Mälarstig, Stefania Bandinelli, Joshua C Bis, Henk Blom, Morris J Brown, Constance Chen, Yii-Der Chen, Robert J Clarke, Abbas Dehghan, Jeanette Erdmann, Luigi Ferrucci, Anders Hamsten, Albert Hofman, David J Hunter, Anuj Goel, Andrew D Johnson, Sekar Kathiresan, Ellen Kampman, Douglas P Kiel, Lambertus ALM Kiemeney, John C Chambers, Peter Kraft, Jan Lindemans, Barbara McKnight, Christopher P Nelson, Christopher J O'Donnell, Bruce M Psaty, Paul M Ridker, Fernando Rivadeneira, Lynda M Rose, Udo Seedorf, David S Siscovick, Heribert Schunkert, Jacob Selhub, Per M Ueland, Peter Vollenweider, Gérard Waeber, Dawn M Waterworth, Hugh Watkins, Jacqueline CM Witteman, Martin den Heijer, Paul Jacques, Andre G Uitterlinden, Jaspal S Kooner, Dan J Rader, Muredach P Reilly, Vincent Mooser, Daniel I Chasman, Nilesh J Samani, Kourosh R Ahmadi

Am J Clin Nutr. 2013 Sep; 98(3): 668–676. Published online 2013 Jul 3. doi: 10.3945/ajcn.112.044545

PMCID:: PMC4321227

Abstract Article PDF–194K

Select item 272201717.

Genetic Variation in Healthy Oldest-Old

Julius Halaschek-Wiener, Mahsa Amirabbasi-Beik, Nasim Monfared, Markus Pieczyk, Christian Sailer, Anita Kollar, Ruth Thomas, Georgios Agalaridis, So Yamada, Lisa Oliveira, Jennifer A. Collins, Graydon Meneilly, Marco A. Marra, Kenneth M. Madden, Nhu D. Le, Joseph M. Connors, Angela R. Brooks-Wilson

PLoS One. 2009; 4(8): e6641. Published online 2009 Aug 14. doi: 10.1371/journal.pone.0006641

PMCID:: PMC2722017

Abstract Article PDF–160K

Select item 266429918.

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women

Rachel T. Palmieri, Melanie A. Wilson, Edwin S. Iversen, Merlise A. Clyde, Brian Calingaert, Patricia G. Moorman, Charles Poole, A. Rebecca Anderson, Stephanie Anderson, Hoda Anton-Culver, Australian Cancer Study (Ovarian Cancer Group), Australian Ovarian Cancer Study Group, Jonathan Beesley, Estrid Hogdall, Wendy Brewster, Michael E. Carney, Xiaoqing Chen, Georgia Chenevix-Trench, Jenny Chang-Claude, Julie M. Cunningham, Richard A. DiCioccio, Jennifer A. Doherty, Douglas F. Easton, Christopher K. Edlund, Simon A. Gayther, Aleksandra Gentry-Maharaj, Ellen L. Goode, Marc T. Goodman, Susanne Kruger Kjaer, Claus K Hogdall, Michael P. Hopkins, Eric L. Jenison, Jan Blaakaer, Galina Lurie, Valerie McGuire, Usha Menon, Kirsten B. Moysich, Roberta B. Ness, Celeste Leigh Pearce, Paul D.P. Pharoah, Malcolm C. Pike, Susan J. Ramus, Mary Anne Rossing, Honglin Song, Keith Y. Terada, David Van Den Berg, Robert A. Vierkant, Shan Wang-Gohrke, Penelope M. Webb, Alice S. Whittemore, Anna H. Wu, Argyrios Ziogas, Andrew Berchuck, Joellen M. Schildkraut

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Dec; 17(12): 3567–3572. doi: 10.1158/1055-9965.EPI-08-0548

PMCID:: PMC2664299

Abstract Article PDF–345K

Select item 553358519.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Abstract Article PDF–5.9M

Select item 905883620.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

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