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Items: 1 to 20 of 40

1.
The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia
Lisa Rusyn, Sebastian Reinartz, Anastasia Nikiforov, Nelly Mikhael, Alexander vom Stein, Viktoria Kohlhas, Johannes Bloehdorn, Stephan Stilgenbauer, Philipp Lohneis, Reinhard Buettner, Sandra Robrecht, Kirsten Fischer, Christian Pallasch, Michael Hallek, Phuong-Hien Nguyen, Tamina Seeger-Nukpezah
Leukemia. 2022; 36(7): 1794–1805. Published online 2022 May 6. doi: 10.1038/s41375-022-01586-1
PMCID:
PMC9252910
AbstractArticlePDF–4.9M
2.
Tyrosine Y189 in the Substrate Domain of the Adhesion Docking Protein NEDD9 Is Conserved with p130Cas Y253 and Regulates NEDD9-Mediated Migration and Focal Adhesion Dynamics
Jaime B. Baquiran, Peta Bradbury, Geraldine M. O'Neill
PLoS One. 2013; 8(7): e69304. Published online 2013 Jul 9. doi: 10.1371/journal.pone.0069304
PMCID:
PMC3706375
AbstractArticlePDF–2.1M
3.
A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice
Joy L. Little, Victoria Serzhanova, Eugene Izumchenko, Brian L. Egleston, Erica Parise, Andres J. Klein-Szanto, Grace Loudon, Maria Shubina, Sachiko Seo, Mineo Kurokawa, Michael F. Ochs, Erica A. Golemis
Oncogene. Author manuscript; available in PMC 2014 Jul 23.
Published in final edited form as: Oncogene. 2014 Jan 23; 33(4): 411–420. Published online 2013 Jan 14. doi: 10.1038/onc.2012.607
PMCID:
PMC3628996
AbstractArticlePDF–3.0M
4.
NEDD9 Stabilizes Focal Adhesions, Increases Binding to the Extra-Cellular Matrix and Differentially Effects 2D versus 3D Cell Migration
Jessie Zhong, Jaime B. Baquiran, Navid Bonakdar, Justin Lees, Yu Wooi Ching, Elena Pugacheva, Ben Fabry, Geraldine M. O'Neill
PLoS One. 2012; 7(4): e35058. Published online 2012 Apr 11. doi: 10.1371/journal.pone.0035058
PMCID:
PMC3324407
AbstractArticlePDF–1.5M
5.
Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking Nedd9
Mahendra K. Singh, Eugene Izumchenko, Andres Klein-Szanto, Brian L. Egleston, Marina Wolfson, Erica A. Golemis
Cancer Res. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: Cancer Res. 2010 Nov 1; 70(21): 8907–8916. Published online 2010 Oct 12. doi: 10.1158/0008-5472.CAN-10-0353
PMCID:
PMC2970659
AbstractArticlePDF–1.4M
6.
NEDD9 promotes oncogenic signaling in mammary tumor development
Eugene Izumchenko, Mahendra K. Singh, Olga V. Plotnikova, Nadezhda Tikhmyanova, Joy L. Little, Ilya G. Serebriiskii, Sachiko Seo, Mineo Kurokawa, Brian L. Egleston, Andres Klein-Szanto, Elena N. Pugacheva, Richard R. Hardy, Marina Wolfson, Denise C. Connolly, Erica A. Golemis
Cancer Res. Author manuscript; available in PMC 2010 Sep 15.
Published in final edited form as: Cancer Res. 2009 Sep 15; 69(18): 7198–7206. Published online 2009 Sep 8. doi: 10.1158/0008-5472.CAN-09-0795
PMCID:
PMC2758619
AbstractArticlePDF–2.9M
7.
Actin polymerization‐dependent activation of Cas‐L promotes immunological synapse stability
Luís C Santos, David A Blair, Sudha Kumari, Michael Cammer, Thomas Iskratsch, Olivier Herbin, Konstantina Alexandropoulos, Michael L Dustin, Michael P Sheetz
Immunol Cell Biol. 2016 Nov-Dec; 94(10): 981–993. Published online 2016 Nov 1. doi: 10.1038/icb.2016.61
PMCID:
PMC5121033
AbstractArticlePDF–2.6M
8.
A complex RARE is required for the majority of Nedd9 embryonic expression
Danielle C. Knutson, Margaret Clagett-Dame
Transgenic Res. 2015; 24(1): 123–134. Published online 2014 Aug 14. doi: 10.1007/s11248-014-9825-9
PMCID:
PMC4274375
AbstractArticlePDF–2.5M
9.
Nedd9 restrains renal cystogenesis in Pkd1−/− mice
Anna S. Nikonova, Olga V. Plotnikova, Victoria Serzhanova, Andrey Efimov, Igor Bogush, Kathy Q. Cai, Harvey H. Hensley, Brian L. Egleston, Andres Klein-Szanto, Tamina Seeger-Nukpezah, Erica A. Golemis
Proc Natl Acad Sci U S A. 2014 Sep 2; 111(35): 12859–12864. Published online 2014 Aug 19. doi: 10.1073/pnas.1405362111
PMCID:
PMC4156736
AbstractArticlePDF–1.3M
10.
Myosin IIA Modulates T Cell Receptor Transport and CasL Phosphorylation during Early Immunological Synapse Formation
Yan Yu, Nicole C. Fay, Alexander A. Smoligovets, Hung-Jen Wu, Jay T. Groves
PLoS One. 2012; 7(2): e30704. Published online 2012 Feb 8. doi: 10.1371/journal.pone.0030704
PMCID:
PMC3275606
AbstractArticlePDF–1.8M
11.
Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer
Alexander Y. Deneka, Meghan C. Kopp, Anna S. Nikonova, Anna V. Gaponova, Anna A. Kiseleva, Harvey H. Hensley, Douglas B. Flieder, Ilya G. Serebriiskii, Erica A. Golemis
Cancer Res. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Cancer Res. 2021 Jul 1; 81(13): 3717–3726. Published online 2021 May 18. doi: 10.1158/0008-5472.CAN-20-3626
PMCID:
PMC8277748
AbstractArticlePDF–1.1M
12.
Src Kinase Determines the Dynamic Exchange of the Docking Protein NEDD9 (Neural Precursor Cell Expressed Developmentally Down-regulated Gene 9) at Focal Adhesions
Peta Bradbury, Cuc T. Bach, Andre Paul, Geraldine M. O'Neill
J Biol Chem. 2014 Sep 5; 289(36): 24792–24800. Published online 2014 Jul 24. doi: 10.1074/jbc.M113.544106
PMCID:
PMC4155648
AbstractArticlePDF–2.4M
13.
SHEP1 partners with CasL to promote marginal zone B-cell maturation
Cecille D. Browne, Melanie M. Hoefer, Suresh K. Chintalapati, Matthew H. Cato, Yann Wallez, Derek V. Ostertag, Elena B. Pasquale, Robert C. Rickert
Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44): 18944–18949. Published online 2010 Oct 18. doi: 10.1073/pnas.1007558107
PMCID:
PMC2973925
AbstractArticlePDF–871K
14.
The retinoic acid inducible Cas-family signaling protein Nedd9 regulates neural crest cell migration by modulating adhesion and actin dynamics
Jorge B. Aquino, François Lallemend, Frédéric Marmigère, Igor Adameyko, Erica A. Golemis, Patrik Ernfors
Neuroscience. Author manuscript; available in PMC 2010 Sep 15.
Published in final edited form as: Neuroscience. 2009 Sep 15; 162(4): 1106–1119. Published online 2009 May 21. doi: 10.1016/j.neuroscience.2009.05.035
PMCID:
PMC2797478
AbstractArticlePDF–2.3M
15.
NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension
Andriy O. Samokhin, Thomas Stephens, Bradley M. Wertheim, Rui-Sheng Wang, Sara O. Vargas, Lai-Ming Yung, Minwei Cao, Marcel Brown, Elena Arons, Paul B. Dieffenbach, Jason G. Fewell, Majed Matar, Frederick P. Bowman, Kathleen J. Haley, George A. Alba, Stefano M. Marino, Rahul Kumar, Ivan O. Rosas, Aaron B. Waxman, William M. Oldham, Dinesh Khanna, Brian B. Graham, Sachiko Seo, Vadim N. Gladyshev, Paul B. Yu, Laura E. Fredenburgh, Joseph Loscalzo, Jane A. Leopold, Bradley A. Maron
Sci Transl Med. Author manuscript; available in PMC 2018 Dec 13.
Published in final edited form as: Sci Transl Med. 2018 Jun 13; 10(445): eaap7294. doi: 10.1126/scitranslmed.aap7294
PMCID:
PMC6223025
AbstractArticlePDF–2.3M
16.
Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis
Yasunori Omata, Shinya Nakamura, Takuma Koyama, Tetsuro Yasui, Jun Hirose, Naohiro Izawa, Takumi Matsumoto, Yuuki Imai, Sachiko Seo, Mineo Kurokawa, Shuichi Tsutsumi, Yuho Kadono, Chikao Morimoto, Hiroyuki Aburatani, Takeshi Miyamoto, Sakae Tanaka
PLoS One. 2016; 11(6): e0157992. Published online 2016 Jun 23. doi: 10.1371/journal.pone.0157992
PMCID:
PMC4918979
AbstractArticlePDF–6.2M
17.
NEDD9 and BCAR1 Negatively Regulate E-Cadherin Membrane Localization, and Promote E-Cadherin Degradation
Nadezhda Tikhmyanova, Erica A. Golemis
PLoS One. 2011; 6(7): e22102. Published online 2011 Jul 12. doi: 10.1371/journal.pone.0022102
PMCID:
PMC3134485
AbstractArticlePDF–6.8M
18.
“NEDD9 Regulates Actin Dynamics through Cortactin Deacetylation in an AURKA/HDAC6-dependent Manner”
Varvara K. Kozyreva, Sarah L. McLaughlin, Ryan H. Livengood, Robin A. Calkins, Laura C. Kelley, Anuradha Rajulapati, Ryan J. Ice, Matthew B. Smolkin, Scott A. Weed, Elena N. Pugacheva
Mol Cancer Res. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: Mol Cancer Res. 2014 May; 12(5): 681–693. Published online 2014 Feb 26. doi: 10.1158/1541-7786.MCR-13-0654
PMCID:
PMC4020952
AbstractArticlePDF–666K
19.
Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1
S Kivimäe, P-M Martin, D Kapfhamer, Y Ruan, U Heberlein, J L R Rubenstein, B N R Cheyette
Transl Psychiatry. 2011 Sep; 1(9): e43. Published online 2011 Sep 27. doi: 10.1038/tp.2011.41
PMCID:
PMC3309484
AbstractArticlePDF–332K
20.
Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation
Tyler A. Vahedi-Hunter, Jason A. Estep, Kylee A. Rosette, Michael L. Rutlin, Kevin M. Wright, Martin M. Riccomagno
Sci Rep. 2018; 8: 5996. Published online 2018 Apr 16. doi: 10.1038/s41598-018-24261-x
PMCID:
PMC5902548
AbstractArticlePDF–4.6M

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