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Select item 20451301.

Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential

Piu Wong, Masayuki Iwasaki, Tim C.P. Somervaille, Chai Wai Eric So, Michael L. Cleary

Genes Dev. 2007 Nov 1; 21(21): 2762–2774. doi: 10.1101/gad.1602107

Correction in:: Genes Dev. 2007 Nov 15; 21(22): 3017.

PMCID:: PMC2045130

Abstract Article PDF–941K

Select item 35789572.

PBX3 is an important cofactor of HOXA9 in leukemogenesis

Zejuan Li, Zhiyu Zhang, Yuanyuan Li, Stephen Arnovitz, Ping Chen, Hao Huang, Xi Jiang, Gia-Ming Hong, Rejani B. Kunjamma, Haomin Ren, Chunjiang He, Chong-Zhi Wang, Abdel G. Elkahloun, Peter J. M. Valk, Konstanze Döhner, Mary Beth Neilly, Lars Bullinger, Ruud Delwel, Bob Löwenberg, Paul P. Liu, Richard Morgan, Janet D. Rowley, Chun-Su Yuan, Jianjun Chen

Blood. 2013 Feb 21; 121(8): 1422–1431. Prepublished online 2012 Dec 21. doi: 10.1182/blood-2012-07-442004

PMCID:: PMC3578957

Abstract Article

Select item 4198823.

The TALE Homeodomain Protein Pbx2 Is Not Essential for Development and Long-Term Survival

Licia Selleri, Jorge DiMartino, Jan van Deursen, Andrea Brendolan, Mrinmoy Sanyal, Elles Boon, Terence Capellini, Kevin S. Smith, Joon Rhee, Heike Pöpperl, Gerard Grosveld, Michael L. Cleary

Mol Cell Biol. 2004 Jun; 24(12): 5324–5331. doi: 10.1128/MCB.24.12.5324-5331.2004

PMCID:: PMC419882

Abstract Article PDF–628K

Select item 110567054.

Transcription factor PBX4 regulates limb development and haematopoiesis in mice

Yan Ning, Shuguang Duo, Xiwen Lin, Hongbo Zhang, Jifeng Fei, Bao Zhang, Yanyun Zeng, Dan Xie, Jian Chen, Xiaowei Liu, Chunsheng Han

Cell Prolif. 2024 May; 57(5): e13580. Published online 2024 Jan 17. doi: 10.1111/cpr.13580

PMCID:: PMC11056705

Abstract Article PDF–4.5M

Select item 44862255.

Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia

Maria-Paz Garcia-Cuellar, Julia Steger, Elisa Füller, Katrin Hetzner, Robert K. Slany

Haematologica. 2015 Jul; 100(7): 905–913. doi: 10.3324/haematol.2015.124032

PMCID:: PMC4486225

Abstract Article PDF–1.7M

Select item 26330526.

Pbx/Meis Deficiencies Demonstrate Multigenetic Origins of Congenital Heart Disease

Kryn Stankunas, Ching Shang, Karen Y. Twu, Shih-Chu Kao, Nancy A. Jenkins, Neal G. Copeland, Mrinmoy Sanyal, Licia Selleri, Michael L. Cleary, Ching-Pin Chang

Circ Res. Author manuscript; available in PMC 2009 Sep 26.

Published in final edited form as: Circ Res. 2008 Sep 26; 103(7): 702–709. Published online 2008 Aug 21. doi: 10.1161/CIRCRESAHA.108.175489

PMCID:: PMC2633052

Abstract Article PDF–3.3M

Select item 109646167.

Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax

Danyang Li, Yigang Yuan, Chen Meng, Zihan Lin, Min Zhao, Liuzhi Shi, Min Li, Daijiao Ye, Yue Cai, Xiaofei He, Haige Ye, Shujuan Zhou, Haixia Zhou, Shenmeng Gao

Clin Epigenetics. 2024; 16: 48. Published online 2024 Mar 26. doi: 10.1186/s13148-024-01658-2

PMCID:: PMC10964616

Abstract Article PDF–2.4M

Select item 33094848.

Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1

S Kivimäe, P-M Martin, D Kapfhamer, Y Ruan, U Heberlein, J L R Rubenstein, B N R Cheyette

Transl Psychiatry. 2011 Sep; 1(9): e43. Published online 2011 Sep 27. doi: 10.1038/tp.2011.41

PMCID:: PMC3309484

Abstract Article PDF–332K

Select item 3617929.

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

K Monica, N Galili, J Nourse, D Saltman, M L Cleary

Mol Cell Biol. 1991 Dec; 11(12): 6149–6157. doi: 10.1128/mcb.11.12.6149

PMCID:: PMC361792

Summary Page Browse PDF–1.8M

Select item 767350010.

In silico analysis identifies a putative cell-of-origin for BRAF fusion-positive cerebellar pilocytic astrocytoma

Subhi Talal Younes, Betty Herrington

PLoS One. 2020; 15(11): e0242521. Published online 2020 Nov 18. doi: 10.1371/journal.pone.0242521

PMCID:: PMC7673500

Abstract Article PDF–2.8M

Select item 161862011.

Pbx3 Deficiency Results in Central Hypoventilation

Joon Whan Rhee, Akiko Arata, Licia Selleri, Yakop Jacobs, Satoru Arata, Hiroshi Onimaru, Michael L. Cleary

Am J Pathol. 2004 Oct; 165(4): 1343–1350. doi: 10.1016/S0002-9440(10)63392-5

PMCID:: PMC1618620

Abstract Article PDF–2.0M

Select item 720685012.

Functional characterization of a novel PBX1 de novo missense variant identified in a patient with syndromic congenital heart disease

Dimuthu Alankarage, Justin O Szot, Nick Pachter, Anne Slavotinek, Licia Selleri, Joseph T Shieh, David Winlaw, Eleni Giannoulatou, Gavin Chapman, Sally L Dunwoodie

Hum Mol Genet. 2020 May 8; 29(7): 1068–1082. Published online 2019 Oct 18. doi: 10.1093/hmg/ddz231

PMCID:: PMC7206850

Abstract Article PDF–1.5M

Select item 555381213.

Pitx3 and En1 determine the size and molecular programming of the dopaminergic neuronal pool

Willemieke M. Kouwenhoven, Lars von Oerthel, Marten P. Smidt

PLoS One. 2017; 12(8): e0182421. Published online 2017 Aug 11. doi: 10.1371/journal.pone.0182421

PMCID:: PMC5553812

Abstract Article PDF–13M

Select item 495834314.

A unique stylopod patterning mechanism by Shox2-controlled osteogenesis

Wenduo Ye, Yingnan Song, Zhen Huang, Marco Osterwalder, Anja Ljubojevic, Jue Xu, Brent Bobick, Samuel Abassah-Oppong, Ningsheng Ruan, Ross Shamby, Diankun Yu, Lu Zhang, Chen-Leng Cai, Axel Visel, Yanding Zhang, John Cobb, YiPing Chen

Development. 2016 Jul 15; 143(14): 2548–2560. doi: 10.1242/dev.138750

PMCID:: PMC4958343

Abstract Article

Select item 365023015.

Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts

Allan M. Gurtan, Arvind Ravi, Peter B. Rahl, Andrew D. Bosson, Courtney K. JnBaptiste, Arjun Bhutkar, Charles A. Whittaker, Richard A. Young, Phillip A. Sharp

Genes Dev. 2013 Apr 15; 27(8): 941–954. doi: 10.1101/gad.215376.113

PMCID:: PMC3650230

Abstract Article PDF–1.9M

Select item 249274816.

A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle

Libera Berghella, Luciana De Angelis, Tristan De Buysscher, Ali Mortazavi, Stefano Biressi, Sonia V. Forcales, Dario Sirabella, Giulio Cossu, Barbara J. Wold

Genes Dev. 2008 Aug 1; 22(15): 2125–2138. doi: 10.1101/gad.468508

PMCID:: PMC2492748

Abstract Article PDF–967K

Select item 292769717.

Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium

Eric S. Tucker, Maria K. Lehtinen, Tom Maynard, Mariela Zirlinger, Catherine Dulac, Nancy Rawson, Larysa Pevny, Anthony-Samuel LaMantia

Development. 2010 Aug 1; 137(15): 2471–2481. doi: 10.1242/dev.049718

PMCID:: PMC2927697

Abstract Article

Select item 292767318.

Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1

Terence D. Capellini, Giulia Vaccari, Elisabetta Ferretti, Sebastian Fantini, Mu He, Massimo Pellegrini, Laura Quintana, Giuseppina Di Giacomo, James Sharpe, Licia Selleri, Vincenzo Zappavigna

Development. 2010 Aug 1; 137(15): 2559–2569. doi: 10.1242/dev.048819