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Select item 103511371.

A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

Li Wang, Robert M. Rossi, Xiaoting Chen, Jing Chen, Jilian Runyon, Mehak Chawla, Daniel Miller, Carmy Forney, Arthur Lynch, Xuzhe Zhang, Fansheng Kong, Bo Jacobsson, Leah C. Kottyan, Matthew T. Weirauch, Ge Zhang, Louis J. Muglia

BMC Med. 2023; 21: 258. Published online 2023 Jul 17. doi: 10.1186/s12916-023-02973-w

PMCID:: PMC10351137

Abstract Article PDF–1.6M

Select item 95784712.

Angiotensin II type 2 receptor prevents extracellular matrix accumulation in human peritoneal mesothelial cell by ameliorating lipid disorder via LOX‐1 suppression

Jing Liu, Bo Jin, Jian Lu, Yuan Feng, Nan Li, Cheng Wan, Qing-Yan Zhang, Chun-Ming Jiang

Ren Fail. 2022; 44(1): 1687–1697. Published online 2022 Oct 13. doi: 10.1080/0886022X.2022.2133729

PMCID:: PMC9578471

Abstract Article PDF–1.5M

Select item 90537703.

AT2R activation increases in vitro angiogenesis in pregnant human uterine artery endothelial cells

Jay S. Mishra, Dong-Bao Chen, Sathish Kumar

PLoS One. 2022; 17(4): e0267826. Published online 2022 Apr 29. doi: 10.1371/journal.pone.0267826

PMCID:: PMC9053770

Abstract Article PDF–2.9M

Select item 82231274.

Variants in AGTR2 gene in Maya people with COVID-19

Armando Totomoch-Serra, Miriam Givisay Domínguez-Cruz, C. Manterola, Maria de Lourdes Muñoz

Gene. 2021 Aug 30; 795: 145794. Published online 2021 Jun 24. doi: 10.1016/j.gene.2021.145794

PMCID:: PMC8223127

Article PDF–368K

Select item 74104995.

A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm

Michael R Garvin, Christiane Alvarez, J Izaak Miller, Erica T Prates, Angelica M Walker, B Kirtley Amos, Alan E Mast, Amy Justice, Bruce Aronow, Daniel Jacobson

eLife. 2020; 9: e59177. Published online 2020 Jul 7. doi: 10.7554/eLife.59177

PMCID:: PMC7410499

Abstract Article PDF–2.2M

Select item 71982326.

Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients

Gian Paolo Rossi, Viola Sanga, Matthias Barton

eLife. 2020; 9: e57278. Published online 2020 Apr 6. doi: 10.7554/eLife.57278

PMCID:: PMC7198232

Abstract Article PDF–798K

Select item 71675887.

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

Paolo Verdecchia, Claudio Cavallini, Antonio Spanevello, Fabio Angeli

Eur J Intern Med. 2020 Jun; 76: 14–20. Published online 2020 Apr 20. doi: 10.1016/j.ejim.2020.04.037

PMCID:: PMC7167588

Abstract Article PDF–1.1M

Select item 56433918.

Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium

Riccardo Terenzi, Mirko Manetti, Irene Rosa, Eloisa Romano, Felice Galluccio, Serena Guiducci, Lidia Ibba-Manneschi, Marco Matucci-Cerinic

Sci Rep. 2017; 7: 13293. Published online 2017 Oct 16. doi: 10.1038/s41598-017-13746-w

PMCID:: PMC5643391

Abstract Article PDF–6.2M

Select item 55867069.

Association between Angiotensin II Type 2 Receptor Gene A/C3123 Polymorphism and High-Density Lipoprotein Cholesterol with Hypertension in Asymptomatic Women

Kazuhiko Kotani, Naoki Sakane, Nobuyuki Taniguchi

Med Princ Pract. 2012 Dec; 22(1): 65–69. Published online 2012 Aug 3. doi: 10.1159/000339892

PMCID:: PMC5586706

Abstract Article PDF–127K

Select item 552554510.

Structural Basis for Selectivity and Diversity in Angiotensin II Receptors

Haitao Zhang, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L. White, Nilkanth Patel, Anastasiia Sadybekov, Beata Zamlynny, Michael T. Rudd, Kaspar Hollenstein, Alexandra Tolstikova, Thomas A. White, Mark S. Hunter, Uwe Weierstall, Wei Liu, Kerim Babaoglu, Eric L. Moore, Ryan D. Katz, Jennifer M. Shipman, Margarita Garcia-Calvo, Sujata Sharma, Payal Sheth, Stephen M. Soisson, Raymond C. Stevens, Vsevolod Katritch, Vadim Cherezov

Nature. Author manuscript; available in PMC 2017 Oct 5.

Published in final edited form as: Nature. 2017 Apr 20; 544(7650): 327–332. Published online 2017 Apr 5. doi: 10.1038/nature22035

PMCID:: PMC5525545

Abstract Article PDF–4.2M

Select item 498156411.

Suppression of Resting Metabolism by the Angiotensin AT₂ Receptor

Nicole K. Littlejohn, Henry L. Keen, Benjamin J. Weidemann, Kristin E. Claflin, Kevin V. Tobin, Kathleen R. Markan, Sungmi Park, Meghan C. Naber, Francoise A. Gourronc, Nicole A. Pearson, Xuebo Liu, Donald A. Morgan, Aloysius J. Klingelhutz, Matthew J. Potthoff, Kamal Rahmouni, Curt D. Sigmund, Justin L. Grobe

Cell Rep. Author manuscript; available in PMC 2016 Aug 11.

Published in final edited form as: Cell Rep. 2016 Aug 9; 16(6): 1548–1560. Published online 2016 Jul 28. doi: 10.1016/j.celrep.2016.07.003

PMCID:: PMC4981564

Abstract Article PDF–3.0M

Select item 459140312.

Activation of angiotensin II type 2 receptor suppresses TNF-α-induced ICAM-1 via NF-кB: possible role of ACE2

Liping Zhu, Oscar A. Carretero, Jiang Xu, Pamela Harding, Nithya Ramadurai, Xiaosong Gu, Edward Peterson, Xiao-Ping Yang

Am J Physiol Heart Circ Physiol. 2015 Sep; 309(5): H827–H834. Published online 2015 Jul 10. doi: 10.1152/ajpheart.00814.2014

PMCID:: PMC4591403

Abstract Article

Select item 397417013.

The angiotensin II type 2 receptor and the kidney

Helmy M Siragy

J Renin Angiotensin Aldosterone Syst. Author manuscript; available in PMC 2014 Apr 3.

Published in final edited form as: J Renin Angiotensin Aldosterone Syst. 2010 Mar; 11(1): 33–36. Published online 2009 Oct 27. doi: 10.1177/1470320309347786

PMCID:: PMC3974170

Abstract Article PDF–74K

Select item 387708914.

Effects of Angiotensin II Type 2 Receptor Overexpression on the Growth of Hepatocellular Carcinoma Cells In Vitro and In Vivo

Hongyan Du, Zhibing Liang, Yanling Zhang, Feilong Jie, Jinlong Li, Yang Fei, Zhi Huang, Nana Pei, Suihai Wang, Andrew Li, Baihong Chen, Yi Zhang, Colin Sumners, Ming Li, Hongwei Li

PLoS One. 2013; 8(12): e83754. Published online 2013 Dec 31. doi: 10.1371/journal.pone.0083754

PMCID:: PMC3877089

Abstract Article PDF–6.1M

Select item 284688315.

Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice

Chiyo Doi, Noboru Egashira, Atsushi Kawabata, Dharmendra Kumar Maurya, Naomi Ohta, Deepthi Uppalapati, Rie Ayuzawa, Lara Pickel, Yuka Isayama, Deryl Troyer, Susumu Takekoshi, Masaaki Tamura

BMC Cancer. 2010; 10: 67. Published online 2010 Feb 24. doi: 10.1186/1471-2407-10-67