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Select item 105448281.

Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts

Sho Sendo, William B. Kiosses, Shen Yang, Dennis J. Wu, Daniel W. K. Lee, Lin Liu, Yael Aschner, Allison J. Vela, Gregory P. Downey, Eugenio Santelli, Nunzio Bottini

Sci Signal. Author manuscript; available in PMC 2024 Jul 4.

Published in final edited form as: Sci Signal. 2023 Jul 4; 16(792): eabn8668. Published online 2023 Jul 4. doi: 10.1126/scisignal.abn8668

PMCID:: PMC10544828

Abstract Article PDF–3.8M

Select item 92557112.

PTPα promotes fibroproliferative responses after acute lung injury

Yael Aschner, Kelly A. Correll, Keriann M. Beke, Daniel G. Foster, Helen M. Roybal, Meghan R. Nelson, Carly L. Meador, Matthew Strand, Kelsey C. Anderson, Camille M. Moore, Paul R. Reynolds, Katrina W. Kopf, Ellen L. Burnham, Gregory P. Downey

Am J Physiol Lung Cell Mol Physiol. 2022 Jul 1; 323(1): L69–L83. Published online 2022 Jun 7. doi: 10.1152/ajplung.00436.2021

PMCID:: PMC9255711

Abstract Article

Select item 48768643.

Extracellular domain dependence of PTPα transforming activity

Barbara Tremper-Wells, Ross J. Resnick, Xinmin Zheng, Leslie J. Holsinger, David Shalloway

Genes Cells. Author manuscript; available in PMC 2016 May 23.

Published in final edited form as: Genes Cells. 2010 Jun; 15(7): 711–724. Published online 2010 Jun 7. doi: 10.1111/j.1365-2443.2010.01410.x

PMCID:: PMC4876864

Abstract Article PDF–856K

Select item 47702594.

“Receptor protein tyrosine phosphatase alpha enhances rheumatoid synovial fibroblast signaling and promotes arthritis in mice”

Stephanie M. Stanford, Mattias N. D. Svensson, Cristiano Sacchetti, Caila A. Pilo, Dennis J. Wu, William B. Kiosses, Annelie Hellvard, Brith Bergum, German R. Aleman Muench, Christian Elly, Yun-Cai Liu, Jeroen den Hertog, Ari Elson, Jan Sap, Piotr Mydel, David L. Boyle, Maripat Corr, Gary S. Firestein, Nunzio Bottini

Arthritis Rheumatol. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Arthritis Rheumatol. 2016 Feb; 68(2): 359–369. doi: 10.1002/art.39442

PMCID:: PMC4770259

Abstract Article PDF–1.7M

Select item 37610475.

Protein Tyrosine Phosphatase α in the Dorsomedial Striatum Promotes Excessive Ethanol-Drinking Behaviors

Sami Ben Hamida, Emmanuel Darcq, Jun Wang, Su Wu, Khanhky Phamluong, Viktor Kharazia, Dorit Ron

J Neurosci. 2013 Sep 4; 33(36): 14369–14378. doi: 10.1523/JNEUROSCI.1954-13.2013

Correction in:: J Neurosci. 2015 Dec 9; 35(49): 16295–16296.

PMCID:: PMC3761047

Abstract Article PDF–2.1M

Select item 37398146.

Abnormal myelination in the spinal cord of PTPα-knockout mice

Quan-Hong Ma, Tao Xiang, Zara Zhuyun Yang, Xu Zhang, Jude Taylor, Zhi-Cheng Xiao

Cell Adh Migr. 2013 Jul 1; 7(4): 370–376. Published online 2013 Jul 17. doi: 10.4161/cam.25652

PMCID:: PMC3739814

Abstract Article PDF–1.9M

Select item 37342427.

Role of PTPα in the Destruction of Periodontal Connective Tissues

Dhaarmini Rajshankar, Corneliu Sima, Qin Wang, Stephanie R. Goldberg, Mwayi Kazembe, Yongqiang Wang, Michael Glogauer, Gregory P. Downey, Christopher A. McCulloch

PLoS One. 2013; 8(8): e70659. Published online 2013 Aug 5. doi: 10.1371/journal.pone.0070659

PMCID:: PMC3734242

Abstract Article PDF–11M

Select item 860698.

Receptor-Like Protein Tyrosine Phosphatase α Homodimerizes on the Cell Surface

Guoqiang Jiang, Jeroen den Hertog, Tony Hunter

Mol Cell Biol. 2000 Aug; 20(16): 5917–5929. doi: 10.1128/mcb.20.16.5917-5929.2000

PMCID:: PMC86069

Abstract Article PDF–1.9M

Select item 40385069.

Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

Eynat Finkelshtein, Sutada Lotinun, Einat Levy-Apter, Esther Arman, Jeroen den Hertog, Roland Baron, Ari Elson

Mol Biol Cell. 2014 Jun 1; 25(11): 1808–1818. doi: 10.1091/mbc.E14-03-0788

PMCID:: PMC4038506

Abstract Article PDF–1.9M

Select item 400598310.

Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness

Yael Aschner, Anthony P. Khalifah, Natalie Briones, Cory Yamashita, Lior Dolgonos, Scott K. Young, Megan N. Campbell, David W.H. Riches, Elizabeth F. Redente, William J. Janssen, Peter M. Henson, Jan Sap, Nathalie Vacaresse, Andras Kapus, Christopher A.G. McCulloch, Rachel L. Zemans, Gregory P. Downey

Am J Pathol. 2014 May; 184(5): 1489–1502. doi: 10.1016/j.ajpath.2014.01.016

PMCID:: PMC4005983

Abstract Article PDF–2.3M

Select item 332376111.

Nucleotides released from Aβ_1–42-treated microglial cells increase cell migration and Aβ_1–42 uptake through P2Y₂ receptor activation

Hye Jung Kim, Deepa Ajit, Troy S. Peterson, Yanfang Wang, Jean M. Camden, W. Gibson Wood, Grace Y. Sun, Laurie Erb, Michael Petris, Gary A. Weisman

J Neurochem. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: J Neurochem. 2012 Apr; 121(2): 228–238. Published online 2012 Mar 14. doi: 10.1111/j.1471-4159.2012.07700.x

PMCID:: PMC3323761

Abstract Article PDF–945K

Select item 163536412.

Tyrosine Phosphatases ε and α Perform Specific and Overlapping Functions in Regulation of Voltage-gated Potassium Channels in Schwann Cells

Zohar Tiran, Asher Peretz, Tal Sines, Vera Shinder, Jan Sap, Bernard Attali, Ari Elson

Mol Biol Cell. 2006 Oct; 17(10): 4330–4342. doi: 10.1091/mbc.E06-02-0151

PMCID:: PMC1635364

Abstract Article PDF–1.2M

Select item 747393313.

Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts

Yael Aschner, Meghan Nelson, Matthew Brenner, Helen Roybal, Keriann Beke, Carly Meador, Daniel Foster, Kelly A. Correll, Paul R. Reynolds, Kelsey Anderson, Elizabeth F. Redente, Jennifer Matsuda, David W. H. Riches, Steve D. Groshong, Ambra Pozzi, Jan Sap, Qin Wang, Dhaarmini Rajshankar, Christopher A. G. McCulloch, Rachel L. Zemans, Gregory P. Downey

Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1; 319(2): L294–L311. Published online 2020 Jun 3. doi: 10.1152/ajplung.00235.2019