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Select item 97943841.

Comparative transcriptional analyses in the nucleus accumbens identifies RGS2 as a key mediator of depression-related behavior

Alexia V. Williams, Catherine J. Peña, Stephanie Ramos-Maciel, Abigail Laman-Maharg, Evelyn Ordonez-Sanchez, Monica Britton, Blythe Durbin-Johnson, Matt Settles, Rebecca Hao, Sae Yokoyama, Christine Xu, Pei X. Luo, Tjien Dwyer, Shanu Bhela, Alexis M. Black, Benoit Labonté, Randal Alex Serafini, Anne Ruiz, Rachael L. Neve, Venetia Zachariou, Eric J. Nestler, Brian C. Trainor

Biol Psychiatry. Author manuscript; available in PMC 2023 Dec 15.

Published in final edited form as: Biol Psychiatry. 2022 Dec 15; 92(12): 942–951. Published online 2022 Jul 5. doi: 10.1016/j.biopsych.2022.06.030

PMCID:: PMC9794384

Abstract Article PDF–1.7M

Select item 96388022.

Elucidating the role of Rgs2 expression in the PVN for metabolic homeostasis in mice

Yue Deng, Jacob E. Dickey, Kenji Saito, Guorui Deng, Uday Singh, Jingwei Jiang, Brandon A. Toth, Zhiyong Zhu, Leonid V. Zingman, Jon M. Resch, Justin L. Grobe, Huxing Cui

Mol Metab. 2022 Dec; 66: 101622. Published online 2022 Oct 25. doi: 10.1016/j.molmet.2022.101622

PMCID:: PMC9638802

Abstract Article PDF–6.8M

Select item 70279313.

Reduced mRNA expression of Regulator of G Protein Signaling-2 (RGS2) in the placenta is associated with human preeclampsia and sufficient to cause features of the disorder in mice

Katherine J. Perschbacher, Guorui Deng, Jeremy A. Sandgren, John W. Walsh, Phillip C. Witcher, Sarah A. Sapouckey, Caitlyn E. Owens, Shao Yang Zhang, Sabrina M. Scroggins, Nicole A. Pearson, Eric J. Devor, Julien A. Sebag, Gary L. Pierce, Rory A. Fisher, Anne E. Kwitek, Donna A. Santillan, Katherine N. Gibson-Corley, Curt D. Sigmund, Mark K. Santillan, Justin L. Grobe

Hypertension. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Hypertension. 2020 Feb; 75(2): 569–579. Published online 2019 Dec 23. doi: 10.1161/HYPERTENSIONAHA.119.14056

PMCID:: PMC7027931

Abstract Article PDF–2.6M

Select item 67890384.

RGS2 drives male aggression in mice via the serotonergic system

Melanie D. Mark, Patric Wollenweber, Annika Gesk, Katja Kösters, Katharina Batzke, Claudia Janoschka, Takashi Maejima, Jing Han, Evan S. Deneris, Stefan Herlitze

Commun Biol. 2019; 2: 373. Published online 2019 Oct 11. doi: 10.1038/s42003-019-0622-0

PMCID:: PMC6789038

Abstract Article PDF–3.4M

Select item 64803995.

Sympathetic nerve traffic and circulating norepinephrine levels in RGS2-deficient mice

Jens Tank, Michael Obst, Andrè Diedrich, Robert J. Brychta, Kendall J. Blumer, Karsten Heusser, Jens Jordan, Friedrich C. Luft, Volkmar Gross

Auton Neurosci. Author manuscript; available in PMC 2019 Apr 24.

Published in final edited form as: Auton Neurosci. 2007 Oct 30; 136(1-2): 52–57. Published online 2007 May 15. doi: 10.1016/j.autneu.2007.04.001

PMCID:: PMC6480399

Abstract Article PDF–292K

Select item 59793286.

Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies

Andrea Schramm, Philip Mueller-Thuemen, Timo Littmann, Manuela Harloff, Takeaki Ozawa, Jens Schlossmann

Int J Mol Sci. 2018 Apr; 19(4): 1180. Published online 2018 Apr 12. doi: 10.3390/ijms19041180

PMCID:: PMC5979328

Abstract Article PDF–26M

Select item 57766857.

RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells

Deborah J. Luessen, Tyler P. Hinshaw, Haigao Sun, Allyn C. Howlett, Glen Marrs, Brian A. McCool, Rong Chen

Neuropharmacology. Author manuscript; available in PMC 2018 Jan 22.

Published in final edited form as: Neuropharmacology. 2016 Nov; 110(Pt A): 297–307. Published online 2016 Aug 12. doi: 10.1016/j.neuropharm.2016.08.009

PMCID:: PMC5776685

Abstract Article PDF–1001K

Select item 55206798.

Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function

H Dong, Y Zhang, J Wang, D S Kim, H Wu, B Sjögren, W Gao, L Luttrell, H Wang

Cell Death Dis. 2017 May; 8(5): e2821. Published online 2017 May 25. doi: 10.1038/cddis.2016.216

PMCID:: PMC5520679

Abstract Article PDF–2.8M

Select item 52491699.

Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation

Tresa George, Matthew Bell, Mainak Chakraborty, David P. Siderovski, Mark A. Giembycz, Robert Newton

PLoS One. 2017; 12(1): e0170269. Published online 2017 Jan 20. doi: 10.1371/journal.pone.0170269

PMCID:: PMC5249169

Abstract Article PDF–2.3M

Select item 496312310.

Inhibition of the Binding between RGS2 and β-Tubulin Interferes with Spindle Formation and Chromosome Segregation during Mouse Oocyte Maturation In Vitro

Man-Xi Jiang, Yan Shi, Zhao-Gui Sun, Zhi Zhang, Yan Zhu

PLoS One. 2016; 11(7): e0159535. Published online 2016 Jul 27. doi: 10.1371/journal.pone.0159535

PMCID:: PMC4963123

Abstract Article PDF–6.3M

Select item 476038511.

RGS2 squelches vascular G_i/o and G_q signaling to modulate myogenic tone and promote uterine blood flow

Li Jie, Elizabeth A. Owens, Lauren A. Plante, Zhuyuan Fang, Derek T. Rensing, Kevin D. Moeller, Patrick Osei‐Owusu

Physiol Rep. 2016 Jan; 4(2): e12692. Published online 2016 Jan 26. doi: 10.14814/phy2.12692

PMCID:: PMC4760385

Abstract Article PDF–1.1M

Select item 450803812.

Regulation of Renal Hemodynamics and Function by RGS2

Patrick Osei-Owusu, Elizabeth A. Owens, Li Jie, Janaina S. Reis, Steven J. Forrester, Tatsuo Kawai, Satoru Eguchi, Harpreet Singh, Kendall J. Blumer

PLoS One. 2015; 10(7): e0132594. Published online 2015 Jul 20. doi: 10.1371/journal.pone.0132594

PMCID:: PMC4508038

Abstract Article PDF–5.2M

Select item 338898813.

Gq/11-Mediated Signaling and Hypertrophy in Mice with Cardiac-Specific Transgenic Expression of Regulator of G-Protein Signaling 2

Cindy Park-Windhol, Peng Zhang, Ming Zhu, Jialin Su, Leonard Chaves, Jr, Angel E. Maldonado, Michelle E. King, Lisa Rickey, Darragh Cullen, Ulrike Mende

PLoS One. 2012; 7(7): e40048. Published online 2012 Jul 3. doi: 10.1371/journal.pone.0040048

PMCID:: PMC3388988

Abstract Article PDF–2.5M

Select item 332100314.

Regulator of G Protein Signaling 2 Deficiency Causes Endothelial Dysfunction and Impaired Endothelium-derived Hyperpolarizing Factor-mediated Relaxation by Dysregulating G_i/o Signaling

Patrick Osei-Owusu, Rasna Sabharwal, Kevin M. Kaltenbronn, Man-Hee Rhee, Mark W. Chapleau, Hans H. Dietrich, Kendall J. Blumer

J Biol Chem. 2012 Apr 6; 287(15): 12541–12549. Published online 2012 Feb 21. doi: 10.1074/jbc.M111.332130

PMCID:: PMC3321003

Abstract Article PDF–2.5M

Select item 301399915.

Renal Actions of RGS2 Control Blood Pressure

Susan B. Gurley, Robert C. Griffiths, Michael E. Mendelsohn, Richard H. Karas, Thomas M. Coffman

J Am Soc Nephrol. 2010 Nov; 21(11): 1847–1851. doi: 10.1681/ASN.2009121306

PMCID:: PMC3013999

Abstract Article

Select item 277668516.

NO-dependent blood pressure regulation in RGS2-deficient mice

Michael Obst, Jens Tank, Ralph Plehm, Kendall J. Blumer, Andrè Diedrich, Jens Jordan, Friedrich C. Luft, Volkmar Gross

Am J Physiol Regul Integr Comp Physiol. Author manuscript; available in PMC 2009 Nov 12.

Published in final edited form as: Am J Physiol Regul Integr Comp Physiol. 2006 Apr; 290(4): R1012–R1019. Published online 2005 Nov 3. doi: 10.1152/ajpregu.00288.2005

PMCID:: PMC2776685

Abstract Article PDF–1.0M

Select item 274218517.

Translational control by RGS2

Chau H. Nguyen, Hong Ming, Peishen Zhao, Lynne Hugendubler, Robert Gros, Scot R. Kimball, Peter Chidiac

J Cell Biol. 2009 Sep 7; 186(5): 755–765. doi: 10.1083/jcb.200811058

PMCID:: PMC2742185

Abstract Article PDF–1.8M

Select item 265071918.

RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival

Miyuki Inoue-Mochita, Toshihiro Inoue, David L. Epstein, Kendall J. Blumer, Ponugoti V. Rao

Mol Vis. 2009; 15: 495–504. Published online 2009 Mar 6.

PMCID:: PMC2650719

Abstract Article PDF–3.1M

Select item 126642919.

Microarray Analyses of Gene Expression during Chondrocyte Differentiation Identifies Novel Regulators of Hypertrophy

Claudine G. James, C. Thomas G. Appleton, Veronica Ulici, T. Michael Underhill, Frank Beier

Mol Biol Cell. 2005 Nov; 16(11): 5316–5333. doi: 10.1091/mbc.E05-01-0084

PMCID:: PMC1266429

Abstract Article PDF–612K

Select item 15191820.

Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice

Scott P. Heximer, Russell H. Knutsen, Xiaoguang Sun, Kevin M. Kaltenbronn, Man-Hee Rhee, Ning Peng, Antonio Oliveira-dos-Santos, Josef M. Penninger, Anthony J. Muslin, Thomas H. Steinberg, J. Michael Wyss, Robert P. Mecham, Kendall J. Blumer

J Clin Invest. 2003 Feb 15; 111(4): 445–452. doi: 10.1172/JCI15598

PMCID:: PMC151918

Abstract Article PDF–1.0M

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