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Select item 35699891.

RNF4 is required for DNA double-strand break repair in vivo

R Vyas, R Kumar, F Clermont, A Helfricht, P Kalev, P Sotiropoulou, I A Hendriks, E Radaelli, T Hochepied, C Blanpain, A Sablina, H van Attikum, J V Olsen, A G Jochemsen, A C O Vertegaal, J-C Marine

Cell Death Differ. 2013 Mar; 20(3): 490–502. Published online 2012 Nov 30. doi: 10.1038/cdd.2012.145

PMCID:: PMC3569989

Abstract Article PDF–4.4M

Select item 31040142.

RING DOMAIN DIMERIZATION IS ESSENTIAL FOR RNF4 FUNCTION

Chu Wai Liew, Huaiyu Sun, Tony Hunter, Catherine L. Day

Biochem J. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Biochem J. 2010 Oct 1; 431(1): 23–29. doi: 10.1042/BJ20100957

PMCID:: PMC3104014

Abstract Article PDF–1.5M

Select item 110936043.

RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication

Joonyoung Her, Haiyan Zheng, Samuel F. Bunting

J Clin Invest. 2024 May 15; 134(10): e167419. Published online 2024 Mar 26. doi: 10.1172/JCI167419

PMCID:: PMC11093604

Abstract Article PDF–5.2M

Select item 81993624.

The E3 Ubiquitin-Protein Ligase RNF4 Promotes TNF-α-Induced Cell Death Triggered by RIPK1

Tatsuya Shimada, Yuki Kudoh, Takuya Noguchi, Tomohiro Kagi, Midori Suzuki, Mei Tsuchida, Hiromu Komatsu, Miki Takahashi, Yusuke Hirata, Atsushi Matsuzawa

Int J Mol Sci. 2021 Jun; 22(11): 5796. Published online 2021 May 28. doi: 10.3390/ijms22115796

PMCID:: PMC8199362

Abstract Article PDF–4.7M

Select item 100918755.

CSF2RB overexpression promotes the protective effects of mesenchymal stromal cells against ischemic heart injury

Tingting Qi, Xiaoming Xu, Yongzhen Guo, Yunlong Xia, Lu Peng, Congye Li, Fengyue Ding, Chao Gao, Miaomiao Fan, Min Yu, Huishou Zhao, Yuan He, Wenli Li, Chunxu Hai, Erhe Gao, Xing Zhang, Feng Gao, Yanhong Fan, Wenjun Yan, Ling Tao

Theranostics. 2023; 13(6): 1759–1773. Published online 2023 Mar 13. doi: 10.7150/thno.81336

PMCID:: PMC10091875

Abstract Article PDF–7.4M

Select item 38146466.

RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells

Ryan L. Ragland, Sima Patel, Rebecca S. Rivard, Kevin Smith, Ashley A. Peters, Anja-Katrin Bielinsky, Eric J. Brown

Genes Dev. 2013 Oct 15; 27(20): 2259–2273. doi: 10.1101/gad.223180.113

PMCID:: PMC3814646

Abstract Article PDF–1.6M

Select item 53632177.

Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis

Yu Liu, Dan Zhao, Fang Qiu, Ling-Ling Zhang, Shang-Kun Liu, Yuan-Yuan Li, Mei-Tong Liu, Di Wu, Jia-Xin Wang, Xiao-Qing Ding, Yan-Xin Liu, Chang-Jiang Dong, Xiao-Qi Shao, Bao-Feng Yang, Wen-Feng Chu

Mol Ther. 2017 Mar 1; 25(3): 666–678. Published online 2017 Jan 28. doi: 10.1016/j.ymthe.2016.12.021

PMCID:: PMC5363217

Abstract Article PDF–4.5M

Select item 34456148.

Requirement of PML SUMO Interacting Motif for RNF4- or Arsenic Trioxide-Induced Degradation of Nuclear PML Isoforms

Mohamed Ali Maroui, Sabrina Kheddache-Atmane, Faten El Asmi, Laurent Dianoux, Muriel Aubry, Mounira K. Chelbi-Alix

PLoS One. 2012; 7(9): e44949. Published online 2012 Sep 18. doi: 10.1371/journal.pone.0044949

PMCID:: PMC3445614

Abstract Article PDF–3.9M

Select item 41355919.

Multiple Arkadia/RNF111 Structures Coordinate Its Polycomb Body Association and Transcriptional Control

Huaiyu Sun, Yijing Liu, Tony Hunter

Mol Cell Biol. 2014 Aug; 34(16): 2981–2995. doi: 10.1128/MCB.00036-14

PMCID:: PMC4135591

Abstract Article PDF–2.2M

Select item 293056010.

Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen

Xiaoyi V. Hu, Tânia M. A. Rodrigues, Haiyan Tao, Robert K. Baker, Loren Miraglia, Anthony P. Orth, Gary E. Lyons, Peter G. Schultz, Xu Wu

Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34): 15087–15092. Published online 2010 Aug 9. doi: 10.1073/pnas.1009025107

PMCID:: PMC2930560

Abstract Article PDF–1010K

Select item 223067411.

Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins

Huaiyu Sun, Joel D Leverson, Tony Hunter

EMBO J. 2007 Sep 19; 26(18): 4102–4112. Published online 2007 Aug 30. doi: 10.1038/sj.emboj.7601839

PMCID:: PMC2230674

Abstract Article PDF–412K

Select item 421008812.

RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response

Lynda M Groocock, Minghua Nie, John Prudden, Davide Moiani, Tao Wang, Anton Cheltsov, Robert P Rambo, Andrew S Arvai, Chiharu Hitomi, John A Tainer, Karolin Luger, J Jefferson P Perry, Eros Lazzerini-Denchi, Michael N Boddy

EMBO Rep. 2014 May; 15(5): 601–608. Published online 2014 Apr 8. doi: 10.1002/embr.201338369

PMCID:: PMC4210088

Abstract Article PDF–1.4M

Select item 408342913.

Structural insight into SUMO chain recognition and manipulation by the ubiquitin ligase RNF4

Yingqi Xu, Anna Plechanovová, Peter Simpson, Jan Marchant, Orsolya Leidecker, Sebastian Kraatz, Ronald T. Hay, Steve J. Matthews

Nat Commun. 2014 Jun 27; 5: 4217. Published online 2014 Jun 27. doi: 10.1038/ncomms5217

PMCID:: PMC4083429

Abstract Article PDF–2.2M

Select item 278209214.

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock

Nadine Martin, Klaus Schwamborn, Valérie Schreiber, Andreas Werner, Christelle Guillier, Xiang-Dong Zhang, Oliver Bischof, Jacob-S Seeler, Anne Dejean

EMBO J. 2009 Nov 18; 28(22): 3534–3548. Published online 2009 Sep 24. doi: 10.1038/emboj.2009.279

PMCID:: PMC2782092

Abstract Article PDF–2.3M

Select item 10909815.

Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription

Anu-Maarit Moilanen, Hetti Poukka, Ulla Karvonen, Marika Häkli, Olli A. Jänne, Jorma J. Palvimo

Mol Cell Biol. 1998 Sep; 18(9): 5128–5139. doi: 10.1128/mcb.18.9.5128

PMCID:: PMC109098

Abstract Article PDF–1.1M

Select item 444563416.

A cellular system that degrades misfolded proteins and protects against neurodegeneration

Lili Guo, Benoit I. Giasson, Alex Glavis-Bloom, Michael D. Brewer, James Shorter, Aaron D. Gitler, Xiaolu Yang

Mol Cell. Author manuscript; available in PMC 2015 Jul 3.

Published in final edited form as: Mol Cell. 2014 Jul 3; 55(1): 15–30. Published online 2014 May 29. doi: 10.1016/j.molcel.2014.04.030

PMCID:: PMC4445634

Abstract Article PDF–2.4M

Select item 399880517.

Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins

Umut Sahin, Omar Ferhi, Marion Jeanne, Shirine Benhenda, Caroline Berthier, Florence Jollivet, Michiko Niwa-Kawakita, Orestis Faklaris, Niclas Setterblad, Hugues de Thé, Valérie Lallemand-Breitenbach

J Cell Biol. 2014 Mar 17; 204(6): 931–945. doi: 10.1083/jcb.201305148

PMCID:: PMC3998805

Abstract Article PDF–3.5M

Select item 311015118.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 18788519.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Abstract Article PDF–287K

Select item 16551120.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Abstract Article PDF–217K

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