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Select item 107222911.

The thyroid hormone enhances mouse embryonic fibroblasts reprogramming to pluripotent stem cells: role of the nuclear receptor corepressor 1

Constanza Contreras-Jurado, Ana Montero-Pedrazuela, Raúl F. Pérez, Susana Alemany, Mario F. Fraga, Ana Aranda

Front Endocrinol (Lausanne) 2023; 14: 1235614. Published online 2023 Dec 1. doi: 10.3389/fendo.2023.1235614

PMCID:: PMC10722291

Abstract Article PDF–7.6M

Select item 104481982.

Chaperone-mediated autophagy dysregulation during aging impairs hepatic fatty acid oxidation via accumulation of NCoR1

You-Jin Choi, Sung Ho Yun, Jihyeon Yu, Yewon Mun, Wonseok Lee, Cheon Jun Park, Byung Woo Han, Byung-Hoon Lee

Mol Metab. 2023 Oct; 76: 101784. Published online 2023 Jul 29. doi: 10.1016/j.molmet.2023.101784

PMCID:: PMC10448198

Abstract Article PDF–3.2M

Select item 77922663.

Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice

Lin‐Juan Du, Jian‐Yong Sun, Wu‐Chang Zhang, Yong‐Li Wang, Hong Zhu, Ting Liu, Ming‐Zhu Gao, Chen Zheng, Yu‐Yao Zhang, Yuan Liu, Yan Liu, Shuai Shao, Xue‐Qing Zhang, Qibin Leng, Johan Auwerx, Sheng‐Zhong Duan

J Am Heart Assoc. 2020 Aug 4; 9(15): e015862. Published online 2020 Jul 28. doi: 10.1161/JAHA.120.015862

PMCID:: PMC7792266

Abstract Article PDF–3.3M

Select item 75880694.

Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism

Michael L. Goodson, Trina A. Knotts, Elsie L. Campbell, Chelsea A. Snyder, Briana M. Young, Martin L. Privalsky

PLoS One. 2020; 15(10): e0241238. Published online 2020 Oct 26. doi: 10.1371/journal.pone.0241238

PMCID:: PMC7588069

Abstract Article PDF–3.3M

Select item 72294815.

NCoR1 Protects Mice From Dextran Sodium Sulfate–Induced Colitis by Guarding Colonic Crypt Cells From Luminal Insult

Elvira Mennillo, Xiaojing Yang, Miles Paszek, Johan Auwerx, Christopher Benner, Shujuan Chen

Cell Mol Gastroenterol Hepatol. 2020; 10(1): 133–147. Published online 2020 Feb 7. doi: 10.1016/j.jcmgh.2020.01.014

PMCID:: PMC7229481

Abstract Article PDF–3.5M

Select item 71475186.

NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4⁺ T Cells

Daniela Hainberger, Valentina Stolz, Ci Zhu, Michael Schuster, Lena Müller, Patricia Hamminger, Ramona Rica, Darina Waltenberger, Marlis Alteneder, Thomas Krausgruber, Anastasiya Hladik, Sylvia Knapp, Christoph Bock, Michael Trauner, Michael A. Farrar, Wilfried Ellmeier

Front Immunol. 2020; 11: 579. Published online 2020 Apr 3. doi: 10.3389/fimmu.2020.00579

PMCID:: PMC7147518

Abstract Article PDF–4.0M

Select item 68352027.

Nuclear receptor corepressor 1 represses cardiac hypertrophy

Chao Li, Xue‐Nan Sun, Bo‐Yan Chen, Meng‐Ru Zeng, Lin‐Juan Du, Ting Liu, Hui‐Hui Gu, Yuan Liu, Yu‐Lin Li, Lu‐Jun Zhou, Xiao‐Jun Zheng, Yu‐Yao Zhang, Wu‐Chang Zhang, Yan Liu, Chaoji Shi, Shuai Shao, Xue‐Rui Shi, Yi Yi, Xu Liu, Jun Wang, Johan Auwerx, Zhao V Wang, Feng Jia, Ruo‐Gu Li, Sheng‐Zhong Duan

EMBO Mol Med. 2019 Nov 7; 11(11): e9127. Published online 2019 Sep 18. doi: 10.15252/emmm.201809127

PMCID:: PMC6835202

Abstract Article PDF–3.7M

Select item 67443958.

NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance

Abdul Ahad, Mathias Stevanin, Shuchi Smita, Gyan Prakash Mishra, Dheerendra Gupta, Sebastian Waszak, Uday Aditya Sarkar, Soumen Basak, Bhawna Gupta, Hans Acha-Orbea, Sunil Kumar Raghav

iScience. 2019 Sep 27; 19: 996–1011. Published online 2019 Aug 17. doi: 10.1016/j.isci.2019.08.024

PMCID:: PMC6744395

Abstract Article PDF–16M

Select item 66611139.

Distinct Role of Nuclear Receptor Corepressor 1 Regulated De Novo Fatty Acids Synthesis in Liver Regeneration and Hepatocarcinogenesis in Mice

Qing Ou-Yang, Xi-Meng Lin, Yan-Jing Zhu, Bo Zheng, Liang Li, Ying-Cheng Yang, Guo-Jun Hou, Xin Chen, Gui-Juan Luo, Feng Huo, Qi-Bin Leng, Frank J. Gonzalez, Xiao-Qing Jiang, Hong-Yang Wang, Lei Chen

Hepatology. Author manuscript; available in PMC 2019 Jul 28.

Published in final edited form as: Hepatology. 2018 Mar; 67(3): 1071–1087. Published online 2018 Jan 26. doi: 10.1002/hep.29562

PMCID:: PMC6661113

Abstract Article PDF–3.0M

Select item 639166610.

The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo

Xiaoling Wan, Lulu Liu, Peipei Zhou, Xinhui Hui, Qiaomei He, Fangfang Yu, Wei Zhang, Xiaodan Ding, Xiujie Yuan, Na Zhang, Yingxi Zhao, Ruihong Zhu, Yuanhua Liu, Pei Hao, Johan Auwerx, Xianmin Song, Qibin Leng, Yan Zhang

Blood Adv. 2019 Feb 26; 3(4): 644–657. Published online 2019 Feb 25. doi: 10.1182/bloodadvances.2018022756

PMCID:: PMC6391666

Abstract Article PDF–2.2M

Select item 569829711.

The corepressor NCOR1 regulates the survival of single-positive thymocytes

Lena Müller, Daniela Hainberger, Valentina Stolz, Patricia Hamminger, Hammad Hassan, Teresa Preglej, Nicole Boucheron, Shinya Sakaguchi, G. Jan Wiegers, Andreas Villunger, Johan Auwerx, Wilfried Ellmeier

Sci Rep. 2017; 7: 15928. Published online 2017 Nov 21. doi: 10.1038/s41598-017-15918-0

PMCID:: PMC5698297

Abstract Article PDF–2.5M

Select item 424871912.

Alteration of NCoR Corepressor Splicing in Mice Causes Increased Body Weight and Hepatosteatosis without Glucose Intolerance

Michael L. Goodson, Briana M. Young, Chelsea A. Snyder, Amy C. Schroeder, Martin L. Privalsky

Mol Cell Biol. 2014 Nov; 34(22): 4104–4114. doi: 10.1128/MCB.00554-14

PMCID:: PMC4248719

Abstract Article PDF–3.3M

Select item 338654413.

The Nuclear Receptor Corepressor (NCoR) Controls Thyroid Hormone Sensitivity and the Set Point of the Hypothalamic-Pituitary-Thyroid Axis

Inna Astapova, Kristen R. Vella, Preeti Ramadoss, Kaila A. Holtz, Benjamin A. Rodwin, Xiao-Hui Liao, Roy E. Weiss, Michael A. Rosenberg, Anthony Rosenzweig, Anthony N. Hollenberg

Mol Endocrinol. 2011 Feb; 25(2): 212–224. Published online 2011 Jan 14. doi: 10.1210/me.2010-0462

PMCID:: PMC3386544

Abstract Article

Select item 122411914.

Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).

Cor A Berrevoets, Arzu Umar, Jan Trapman, Albert O Brinkmann

Biochem J. 2004 May 1; 379(Pt 3): 731–738. doi: 10.1042/BJ20031456

PMCID:: PMC1224119

Summary PDF–220K

Select item 1020374515.

Interaction between poly(A)–binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response

A.G. Oliveira, L.D. Oliveira, M.V. Cruz, D.S.P.S.F. Guimarães, T.I. Lima, B.C. Santos-Fávero, A.D. Luchessi, B.A. Pauletti, A.P. Leme, M.C. Bajgelman, J. Afonso, L.C.A. Regitano, H.F. Carvalho, E.M. Carneiro, J. Kobarg, V. Perissi, J. Auwerx, L.R. Silveira

J Biol Chem. 2023 Jun; 299(6): 104702. Published online 2023 Apr 12. doi: 10.1016/j.jbc.2023.104702

PMCID:: PMC10203745

Abstract Article PDF–2.9M

Select item 980425016.

NCoR1 controls immune tolerance in conventional dendritic cells by fine-tuning glycolysis and fatty acid oxidation

Kaushik Sen, Rashmirekha Pati, Atimukta Jha, Gyan Prakash Mishra, Subhasish Prusty, Shweta Chaudhary, Swati Swetalika, Sreeparna Podder, Aishwarya Sen, Mamuni Swain, Ranjan Kumar Nanda, Sunil K. Raghav

Redox Biol. 2023 Feb; 59: 102575. Published online 2022 Dec 16. doi: 10.1016/j.redox.2022.102575

PMCID:: PMC9804250

Abstract Article PDF–14M

Select item 577216917.

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

Zsolt Czimmerer, Bence Daniel, Attila Horvath, Dominik Rückerl, Gergely Nagy, Mate Kiss, Matthew Peloquin, Marietta M. Budai, Ixchelt Cuaranta-Monroy, Zoltan Simandi, Laszlo Steiner, Bela Nagy, Jr., Szilard Poliska, Csaba Banko, Zsolt Bacso, Ira G. Schulman, Sascha Sauer, Jean-Francois Deleuze, Judith E. Allen, Szilvia Benko, Laszlo Nagy

Immunity. 2018 Jan 16; 48(1): 75–90.e6. doi: 10.1016/j.immuni.2017.12.010

PMCID:: PMC5772169

Abstract Article

Select item 574176018.

NCOR1 modulates erythroid disorders caused by mutations of thyroid hormone receptor α1

Cho Rong Han, Sunmi Park, Sheue-yann Cheng

Sci Rep. 2017; 7: 18080. Published online 2017 Dec 22. doi: 10.1038/s41598-017-18409-4

PMCID:: PMC5741760

Abstract Article PDF–2.7M

Select item 530000519.

CREBBP inactivation promotes the development of HDAC3 dependent lymphomas

Yanwen Jiang, Ana Ortega-Molina, Huimin Geng, Hsia-Yuan Ying, Katerina Hatzi, Sara Parsa, Dylan McNally, Ling Wang, Ashley S. Doane, Xabier Agirre Ena, Matt Teater, Cem Meydan, Zhuoning Li, David Poloway, Shenqiu Wang, Daisuke Ennishi, David W. Scott, Kristy R. Stengel, Janice E. Kranz, Edward Holson, Sneh Sharma, James W. Young, Chi-Shuen Chu, Robert G. Roeder, Rita Shaknovich, Scott W. Hiebert, Randy D. Gascoyne, Wayne Tam, Olivier Elemento, Hans-Guido Wendel, Ari M. Melnick

Cancer Discov. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Cancer Discov. 2017 Jan; 7(1): 38–53. Published online 2016 Oct 12. doi: 10.1158/2159-8290.CD-16-0975

PMCID:: PMC5300005

Abstract Article PDF–3.4M

Select item 461825620.

Phosphorylation of the Nuclear Receptor Co-repressor 1 by Protein Kinase B (PKB/Akt) Switches its Co-repressor Targets in the Liver

Young Suk Jo, Dongryeol Ryu, Adriano Maida, Xu Wang, Ronald M. Evans, Kristina Schoonjans, Johan Auwerx

Hepatology. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Hepatology. 2015 Nov; 62(5): 1606–1618. Published online 2015 Jul 22. doi: 10.1002/hep.27907

PMCID:: PMC4618256

Abstract Article PDF–2.2M

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