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Select item 72969361.

Altered staining patterns and expression level of Engrailed-2 in benign prostatic hyperplasia and prostate Cancer predict prostatic disease progression

Qi Li, Yibo Shi, Rigai Sa, Jun Hao, Jinhao Hu, Mulun Xiao, Chaoliang Wang, Liang Yan, Baoping Qiao, Guoxun Chen

BMC Cancer. 2020; 20: 555. Published online 2020 Jun 15. doi: 10.1186/s12885-020-07049-z

PMCID:: PMC7296936

Abstract Article PDF–14M

Select item 64357202.

Membrane insertion and secretion of the Engrailed-2 (EN2) transcription factor by prostate cancer cells may induce antiviral activity in the stroma

Natasha Punia, Monika Primon, Guy R. Simpson, Hardev S. Pandha, Richard Morgan

Sci Rep. 2019; 9: 5138. Published online 2019 Mar 26. doi: 10.1038/s41598-019-41678-0

PMCID:: PMC6435720

Abstract Article PDF–2.6M

Select item 61712363.

Engrailed-2 (EN2) – a novel biomarker in epithelial ovarian cancer

Sophie Elena McGrath, Nicola Annels, Thumuluru K. Madhuri, Anil Tailor, Simon A. Butler-Manuel, Richard Morgan, Hardev Pandha, Agnieszka Michael

BMC Cancer. 2018; 18: 943. Published online 2018 Oct 3. doi: 10.1186/s12885-018-4816-5

PMCID:: PMC6171236

Abstract Article PDF–3.3M

Select item 41117184.

Lineage-specific function of Engrailed-2 in the progression of chronic myelogenous leukemia to T-cell blast crisis

Fernando Abollo-Jiménez, Elena Campos-Sánchez, Amparo Toboso-Navasa, Carolina Vicente-Dueñas, Inés González-Herrero, Esther Alonso-Escudero, Marcos González, Víctor Segura, Óscar Blanco, José Ángel Martínez-Climent, Isidro Sánchez-García, César Cobaleda

Cell Cycle. 2014 Jun 1; 13(11): 1717–1726. Published online 2014 Mar 25. doi: 10.4161/cc.28629

PMCID:: PMC4111718

Abstract Article PDF–5.3M

Select item 36903895.

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men

Emma Killick, Richard Morgan, Francesca Launchbury, Elizabeth Bancroft, Elizabeth Page, Elena Castro, Zsofia Kote-Jarai, Armen Aprikian, Ignacio Blanco, Virginia Clowes, Susan Domchek, Fiona Douglas, Diana Eccles, D. Gareth Evans, Marion Harris, Judy Kirk, Jimmy Lam, Geoffrey Lindeman, Gillian Mitchell, Nicholas Pachter, Christina Selkirk, Kathy Tucker, Janaz Zgajnar, Rosalind Eeles, Hardev Pandha

Sci Rep. 2013; 3: 2059. Published online 2013 Jun 24. doi: 10.1038/srep02059

PMCID:: PMC3690389

Abstract Article PDF–282K

Select item 35909986.

Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum

S J James, Svitlana Shpyleva, Stepan Melnyk, Oleksandra Pavliv, I P Pogribny

Transl Psychiatry. 2013 Feb; 3(2): e232. Published online 2013 Feb 19. doi: 10.1038/tp.2013.8

PMCID:: PMC3590998

Abstract Article PDF–927K

Select item 27834167.

Autism Associated Haplotype Affects the Regulation of the Homeobox Gene, ENGRAILED 2

Rym Benayed, Jiyeon Choi, Paul G Matteson, Neda Gharani, Silky Kamdar, Linda M Brzustowicz, James H Millonig

Biol Psychiatry. Author manuscript; available in PMC 2010 Nov 15.

Published in final edited form as: Biol Psychiatry. 2009 Nov 15; 66(10): 911–917. Published online 2009 Jul 17. doi: 10.1016/j.biopsych.2009.05.027

PMCID:: PMC2783416

Abstract Article PDF–1.2M

Select item 17352568.

No association between the EN2 gene and autistic disorder

H Zhong, F Serajee, R Nabi, A Huq

J Med Genet. 2003 Jan; 40(1): e4. doi: 10.1136/jmg.40.1.e4

PMCID:: PMC1735256

Summary PDF–99K

Select item 13779489.

A genomic screen of autism: evidence for a multilocus etiology.

N Risch, D Spiker, L Lotspeich, N Nouri, D Hinds, J Hallmayer, L Kalaydjieva, P McCague, S Dimiceli, T Pitts, L Nguyen, J Yang, C Harper, D Thorpe, S Vermeer, H Young, J Hebert, A Lin, J Ferguson, C Chiotti, S Wiese-Slater, T Rogers, B Salmon, P Nicholas, P B Petersen, C Pingree, W McMahon, D L Wong, L L Cavalli-Sforza, H C Kraemer, R M Myers

Am J Hum Genet. 1999 Aug; 65(2): 493–507. doi: 10.1086/302497

PMCID:: PMC1377948

Summary PDF–326K

Select item 127139210.

Support for the Homeobox Transcription Factor Gene ENGRAILED 2 as an Autism Spectrum Disorder Susceptibility Locus

Rym Benayed, Neda Gharani, Ian Rossman, Vincent Mancuso, Gloria Lazar, Silky Kamdar, Shannon E. Bruse, Samuel Tischfield, Brett J. Smith, Raymond A. Zimmerman, Emanuel DiCicco-Bloom, Linda M. Brzustowicz, James H. Millonig

Am J Hum Genet. 2005 Nov; 77(5): 851–868. Published online 2005 Oct 5. doi: 10.1086/497705

PMCID:: PMC1271392

Abstract Article PDF–1.2M

Select item 880623311.

Circular RNA circ_0000467 regulates colorectal cancer development via miR-382-5p/EN2 axis

Lu Xie, Zhihong Pan

Bioengineered. 2021; 12(1): 886–897. Published online 2021 Mar 9. doi: 10.1080/21655979.2021.1889130

PMCID:: PMC8806233

Abstract Article PDF–2.2M

Select item 739350112.

EN2 as an oncogene promotes tumor progression via regulating CCL20 in colorectal cancer

Yimin Li, Jiaxin Liu, Qing Xiao, Ruotong Tian, Zhengwei Zhou, Yaqi Gan, Yuanyuan Li, Guang Shu, Gang Yin

Cell Death Dis. 2020 Jul; 11(7): 604. Published online 2020 Jul 30. doi: 10.1038/s41419-020-02804-3

PMCID:: PMC7393501

Abstract Article PDF–2.0M

Select item 554902613.

The biological functions and mechanism of miR-212 in prostate cancer proliferation, migration and invasion via targeting Engrailed-2

Yi Zhou, Zhigang Ji, Weigang Yan, Zhien Zhou, Hanzhong Li

Oncol Rep. 2017 Sep; 38(3): 1411–1419. Published online 2017 Jul 12. doi: 10.3892/or.2017.5805

PMCID:: PMC5549026

Abstract Article PDF–981K

Select item 547633514.

Hsa-miR-27b is up-regulated in cytomegalovirus-infected human glioma cells, targets engrailed-2 and inhibits its expression

Linqian Wang, Ming Yang, Shijing Liao, Wei Liu, Gan Dai, Guojun Wu, Liyu Chen

Exp Biol Med (Maywood) 2017 Jun; 242(12): 1227–1233. Published online 2017 Mar 26. doi: 10.1177/1535370217699535

PMCID:: PMC5476335

Abstract Article PDF–281K

Select item 435052215.

Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum

S J James, S Shpyleva, S Melnyk, O Pavliv, I P Pogribny

Transl Psychiatry. 2014 Oct; 4(10): e460. Published online 2014 Oct 7. doi: 10.1038/tp.2014.87

PMCID:: PMC4350522

Abstract Article PDF–1.1M

Select item 394371016.

EXOME SEQUENCING AND DIFFUSION TENSOR IMAGING IN DEVELOPMENTAL DISABILITIES

Senthil K Sundaram, AHM M Huq, Tammy Hsia, Harry T Chugani

Pediatr Res. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: Pediatr Res. 2014 Mar; 75(3): 443–447. Published online 2013 Dec 6. doi: 10.1038/pr.2013.234

PMCID:: PMC3943710

Abstract Article PDF–397K

Select item 391971917.

Autism Associated Gene, ENGRAILED2, and Flanking Gene Levels Are Altered in Post-Mortem Cerebellum

Jiyeon Choi, Myka R. Ababon, Mai Soliman, Yong Lin, Linda M. Brzustowicz, Paul G. Matteson, James H. Millonig

PLoS One. 2014; 9(2): e87208. Published online 2014 Feb 10. doi: 10.1371/journal.pone.0087208

PMCID:: PMC3919719

Abstract Article PDF–959K

Select item 4176618.

Deregulated expression of PAX5 in medulloblastoma.

Z Kozmik, U Sure, D Rüedi, M Busslinger, A Aguzzi

Proc Natl Acad Sci U S A. 1995 Jun 6; 92(12): 5709–5713. doi: 10.1073/pnas.92.12.5709

PMCID:: PMC41766

Summary Page Browse PDF–1.8M

Select item 889442519.

Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer

Yeongun Lee, So Hee Dho, Jiyeon Lee, Ji-Hyun Hwang, Minjung Kim, Won-Young Choi, Jin-Young Lee, Jongwon Lee, Woochul Chang, Min Young Lee, Jungmin Choi, Tae-You Kim, Lark Kyun Kim

Exp Mol Med. 2022 Feb; 54(2): 156–168. Published online 2022 Feb 15. doi: 10.1038/s12276-022-00731-1

PMCID:: PMC8894425

Abstract Article PDF–3.9M

Select item 667319520.

Progressive Loss of Dopaminergic Neurons in the Ventral Midbrain of Adult Mice Heterozygote for Engrailed1

Laure Sonnier, Gwenaëlle Le Pen, Andreas Hartmann, Jean-Charles Bizot, Fabrice Trovero, Marie-Odile Krebs, Alain Prochiantz

J Neurosci. 2007 Jan 31; 27(5): 1063–1071. doi: 10.1523/JNEUROSCI.4583-06.2007

PMCID:: PMC6673195

Abstract Article PDF–585K

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