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Select item 108640241.

Slc12a2 loss in insulin-secreting β-cells links development of overweight and metabolic dysregulation to impaired satiation control of feeding

Yakshkumar Dilipbhai Rathod, Rana Abdelgawad, Christian A. Hübner, Mauricio Di Fulvio

Am J Physiol Endocrinol Metab. 2023 Nov 1; 325(5): E581–E594. Published online 2023 Oct 11. doi: 10.1152/ajpendo.00197.2023

PMCID:: PMC10864024

Abstract Article

Select item 90274962.

Beta-Amyloid (Aβ_1-42) Increases the Expression of NKCC1 in the Mouse Hippocampus

Patricia Lam, Chitra Vinnakota, Beatriz Calvo-Flores Guzmán, Julia Newland, Katie Peppercorn, Warren P. Tate, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky

Molecules. 2022 Apr; 27(8): 2440. Published online 2022 Apr 10. doi: 10.3390/molecules27082440

PMCID:: PMC9027496

Abstract Article PDF–6.5M

Select item 85311453.

Restoring neuronal chloride homeostasis with anti-NKCC1 gene therapy rescues cognitive deficits in a mouse model of Down syndrome

Martina Parrini, Shovan Naskar, Micol Alberti, Ilaria Colombi, Giovanni Morelli, Anna Rocchi, Marina Nanni, Federica Piccardi, Severine Charles, Giuseppe Ronzitti, Federico Mingozzi, Andrea Contestabile, Laura Cancedda

Mol Ther. 2021 Oct 6; 29(10): 3072–3092. Published online 2021 May 29. doi: 10.1016/j.ymthe.2021.05.023

PMCID:: PMC8531145

Abstract Article PDF–3.9M

Select item 85200194.

Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology

Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill

Nat Commun. 2021; 12: 6035. Published online 2021 Oct 15. doi: 10.1038/s41467-021-25942-4

Correction in:: Nat Commun. 2021; 12: 6988.

PMCID:: PMC8520019

Abstract Article PDF–2.6M

Select item 83907515.

Oligodendrocytic Na⁺-K⁺-Cl^– co-transporter 1 activity facilitates axonal conduction and restores plasticity in the adult mouse brain

Yoshihiko Yamazaki, Yoshifumi Abe, Satoshi Fujii, Kenji F. Tanaka

Nat Commun. 2021; 12: 5146. Published online 2021 Aug 26. doi: 10.1038/s41467-021-25488-5

PMCID:: PMC8390751

Abstract Article PDF–2.9M

Select item 67728716.

Abnormal GABA_A Receptor-Mediated Currents in Dorsal Root Ganglion Neurons Isolated from Na–K–2Cl Cotransporter Null Mice

Ki-Wug Sung, Michael Kirby, Michael P. McDonald, David M. Lovinger, Eric Delpire

J Neurosci. 2000 Oct 15; 20(20): 7531–7538. doi: 10.1523/JNEUROSCI.20-20-07531.2000

PMCID:: PMC6772871

Abstract Article PDF–226K

Select item 67301557.

Na-K-Cl Cotransporter-Mediated Intracellular Na⁺ Accumulation Affects Ca²⁺ Signaling in Astrocytes in an In Vitro Ischemic Model

Brett Lenart, Douglas B. Kintner, Gary E. Shull, Dandan Sun

J Neurosci. 2004 Oct 27; 24(43): 9585–9597. doi: 10.1523/JNEUROSCI.2569-04.2004

PMCID:: PMC6730155

Abstract Article PDF–885K

Select item 66727008.

NKCC1 Phosphorylation Stimulates Neurite Growth of Injured Adult Sensory Neurons

Simon Pieraut, Valérie Laurent-Matha, Chamroeun Sar, Thomas Hubert, Ilana Méchaly, Cécile Hilaire, Marcel Mersel, Eric Delpire, Jean Valmier, Frédérique Scamps

J Neurosci. 2007 Jun 20; 27(25): 6751–6759. doi: 10.1523/JNEUROSCI.1337-07.2007

PMCID:: PMC6672700

Abstract Article PDF–412K

Select item 66704489.

GABAergic Depolarization of the Axon Initial Segment in Cortical Principal Neurons Is Caused by the Na–K–2Cl Cotransporter NKCC1

Stanislav Khirug, Junko Yamada, Ramil Afzalov, Juha Voipio, Leonard Khiroug, Kai Kaila

J Neurosci. 2008 Apr 30; 28(18): 4635–4639. doi: 10.1523/JNEUROSCI.0908-08.2008

PMCID:: PMC6670448

Abstract Article PDF–288K

Select item 666560610.

Compensatory Enhancement of Intrinsic Spiking upon NKCC1 Disruption in Neonatal Hippocampus

Sampsa T. Sipilä, Kristiina Huttu, Junko Yamada, Ramil Afzalov, Juha Voipio, Peter Blaesse, Kai Kaila

J Neurosci. 2009 May 27; 29(21): 6982–6988. doi: 10.1523/JNEUROSCI.0443-09.2009

PMCID:: PMC6665606

Abstract Article PDF–377K

Select item 648267211.

A dileucine motif in the COOH-terminal domain of NKCC1 targets the cotransporter to the plasma membrane

Rainelli Koumangoye, Salma Omer, Eric Delpire

Am J Physiol Cell Physiol. 2019 Apr 1; 316(4): C545–C558. Published online 2019 Mar 13. doi: 10.1152/ajpcell.00023.2019

PMCID:: PMC6482672

Abstract Article

Select item 648267112.

Genetic and pharmacological inactivation of apical Na⁺-K⁺-2Cl⁻ cotransporter 1 in choroid plexus epithelial cells reveals the physiological function of the cotransporter

Jeannine M. C. Gregoriades, Aaron Madaris, Francisco J. Alvarez, Francisco J. Alvarez-Leefmans

Am J Physiol Cell Physiol. 2019 Apr 1; 316(4): C525–C544. Published online 2018 Dec 21. doi: 10.1152/ajpcell.00026.2018

PMCID:: PMC6482671

Abstract Article

Select item 613950513.

Mistargeting of a truncated Na-K-2Cl cotransporter in epithelial cells

Rainelli Koumangoye, Salma Omer, Eric Delpire

Am J Physiol Cell Physiol. 2018 Aug 1; 315(2): C258–C276. Published online 2018 May 2. doi: 10.1152/ajpcell.00130.2018

PMCID:: PMC6139505

Abstract Article

Select item 598689014.

Cotransporter-mediated water transport underlying cerebrospinal fluid formation

Annette B. Steffensen, Eva K. Oernbo, Anca Stoica, Niklas J. Gerkau, Dagne Barbuskaite, Katerina Tritsaris, Christine R. Rose, Nanna MacAulay

Nat Commun. 2018; 9: 2167. Published online 2018 Jun 4. doi: 10.1038/s41467-018-04677-9

PMCID:: PMC5986890

Abstract Article PDF–2.8M

Select item 570247815.

The Role of Na:K:2Cl Cotransporter 1 (NKCC1/SLC12A2) in Dental Epithelium during Enamel Formation in Mice

Rozita Jalali, Johannes C. Lodder, Behrouz Zandieh-Doulabi, Dimitra Micha, James E. Melvin, Marcelo A. Catalan, Huibert D. Mansvelder, Pamela DenBesten, Antonius Bronckers

Front Physiol. 2017; 8: 924. Published online 2017 Nov 21. doi: 10.3389/fphys.2017.00924

PMCID:: PMC5702478

Abstract Article PDF–5.2M

Select item 564888716.

Time-controllable Nkcc1 knockdown replicates reversible hearing loss in postnatal mice

Takahisa Watabe, Ming Xu, Miho Watanabe, Junichi Nabekura, Taiga Higuchi, Karin Hori, Mitsuo P. Sato, Fumiaki Nin, Hiroshi Hibino, Kaoru Ogawa, Masatsugu Masuda, Kenji F. Tanaka

Sci Rep. 2017; 7: 13605. Published online 2017 Oct 19. doi: 10.1038/s41598-017-13997-7

PMCID:: PMC5648887

Abstract Article PDF–2.0M

Select item 553159617.

Spatial and temporal distribution patterns of Na-K-2Cl cotransporter in adult and developing mouse retinas

BAOQIN LI, KELLI McKERNAN, WEN SHEN

Vis Neurosci. Author manuscript; available in PMC 2017 Jul 27.

Published in final edited form as: Vis Neurosci. 2008 Mar-Apr; 25(2): 109–123. doi: 10.1017/S0952523808080164

PMCID:: PMC5531596

Abstract Article PDF–3.4M

Select item 539446218.

Loop diuretics affect skeletal myoblast differentiation and exercise-induced muscle hypertrophy

Shintaro Mandai, Susumu Furukawa, Manami Kodaka, Yutaka Hata, Takayasu Mori, Naohiro Nomura, Fumiaki Ando, Yutaro Mori, Daiei Takahashi, Yuki Yoshizaki, Yuri Kasagi, Yohei Arai, Emi Sasaki, Sayaka Yoshida, Yasuro Furuichi, Nobuharu L. Fujii, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida

Sci Rep. 2017; 7: 46369. Published online 2017 Apr 18. doi: 10.1038/srep46369

PMCID:: PMC5394462

Abstract Article PDF–1.2M

Select item 536819119.

NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility

Fushun Wang, Xiaowei Wang, Lee A. Shapiro, Maria L. Cotrina, Weimin Liu, Ernest W. Wang, Simeng Gu, Wei Wang, Xiaosheng He, Maiken Nedergaard, Jason H. Huang

Brain Struct Funct. 2017; 222(3): 1543–1556. Published online 2016 Sep 1. doi: 10.1007/s00429-016-1292-z

PMCID:: PMC5368191

Abstract Article PDF–6.4M

Select item 475318020.

Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine

Emily M Bradford, Kanimozhi Vairamani, Gary E Shull

World J Gastrointest Pathophysiol. 2016 Feb 15; 7(1): 138–149. Published online 2016 Feb 15. doi: 10.4291/wjgp.v7.i1.138

PMCID:: PMC4753180

Abstract Article PDF–1.7M

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