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Items: 1 to 20 of 221

1.
Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8+ T cell memory development
Stefania D’Aria, Céline Maquet, Shuang Li, Suveera Dhup, Anouk Lepez, Arnaud Kohler, Vincent F. Van Hée, Rajesh K. Dadhich, Marine Frenière, Fabienne Andris, Ivan Nemazanyy, Pierre Sonveaux, Bénédicte Machiels, Laurent Gillet, Michel Y. Braun
Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13): e2306763121. Published online 2024 Mar 18. doi: 10.1073/pnas.2306763121
PMCID:
PMC10990098
AbstractArticlePDF–4.6M
2.
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Maria Rodriguez-Zabala, Ramprasad Ramakrishnan, Katrin Reinbach, Somadri Ghosh, Leal Oburoglu, Antoni Falqués-Costa, Kishan Bellamkonda, Mats Ehinger, Pablo Peña-Martínez, Noelia Puente-Moncada, Henrik Lilljebjörn, Jörg Cammenga, Cornelis Jan Pronk, Vladimir Lazarevic, Thoas Fioretos, Anna K. Hagström-Andersson, Niels-Bjarne Woods, Marcus Järås
Blood Adv. 2023 Sep 26; 7(18): 5382–5395. Published online 2023 Jul 30. doi: 10.1182/bloodadvances.2023009967
PMCID:
PMC10509671
AbstractArticlePDF–1.4M
3.
Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome
Naeimeh Tayebi, Brian Leon‐Ricardo, Kevin McCall, Elvisa Mehinovic, Kristin Engelstad, Vincent Huynh, Tychele N. Turner, Judy Weisenberg, Liu L. Thio, Paul Hruz, Robin S. B. Williams, Darryl C. De Vivo, Vincent Petit, Gabe Haller, Christina A. Gurnett
Ann Clin Transl Neurol. 2023 May; 10(5): 787–801. Published online 2023 Mar 31. doi: 10.1002/acn3.51767
PMCID:
PMC10187726
AbstractArticlePDF–1.1M
4.
Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake
Shawna L. McMillin, Parker L. Evans, William M. Taylor, Luke A. Weyrauch, Tyler J. Sermersheim, Steven S. Welc, Monique R. Heitmeier, Richard C. Hresko, Paul W. Hruz, Francoise Koumanov, Geoffrey D. Holman, E. Dale Abel, Carol A. Witczak
Biomolecules. 2022 Dec; 12(12): 1734. Published online 2022 Nov 23. doi: 10.3390/biom12121734
PMCID:
PMC9776291
AbstractArticlePDF–1.1M
5.
A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism
Andrea Aparicio, Erika T. Camacho, Nancy J. Philp, Stephen A. Wirkus
Sci Rep. 2022; 12: 10645. Published online 2022 Jun 23. doi: 10.1038/s41598-022-13950-3
PMCID:
PMC9226191
AbstractArticlePDF–2.2M
6.
Reduction of Glut1 in the Neural Retina But Not the RPE Alleviates Polyol Accumulation and Normalizes Early Characteristics of Diabetic Retinopathy
Nicholas C. Holoman, Jacob J. Aiello, Timothy D. Trobenter, Matthew J. Tarchick, Michael R. Kozlowski, Emily R. Makowski, Darryl C. De Vivo, Charandeep Singh, Jonathan E. Sears, Ivy S. Samuels
J Neurosci. 2021 Apr 7; 41(14): 3275–3299. doi: 10.1523/JNEUROSCI.2010-20.2021
PMCID:
PMC8026348
AbstractArticlePDF–5.2M
7.
Diabetes fuels periodontal lesions via GLUT1-driven macrophage inflammaging
Qian Wang, Lulingxiao Nie, Pengfei Zhao, Xinyi Zhou, Yi Ding, Qianming Chen, Qi Wang
Int J Oral Sci. 2021; 13: 11. Published online 2021 Mar 24. doi: 10.1038/s41368-021-00116-6
PMCID:
PMC7990943
AbstractArticlePDF–2.8M
8.
An early endothelial cell–specific requirement for Glut1 is revealed in Glut1 deficiency syndrome model mice
Maoxue Tang, Sarah H. Park, Sabrina Petri, Hang Yu, Carlos B. Rueda, E. Dale Abel, Carla Y. Kim, Elizabeth M.C. Hillman, Fanghua Li, Yeojin Lee, Lei Ding, Smitha Jagadish, Wayne N. Frankel, Darryl C. De Vivo, Umrao R. Monani
JCI Insight. 2021 Feb 8; 6(3): e145789. Published online 2021 Feb 8. doi: 10.1172/jci.insight.145789
PMCID:
PMC7934852
AbstractArticlePDF–17M
9.
Alzheimer amyloid-β- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood
Rachel D. Hendrix, Yang Ou, Jakeira E. Davis, Angela K. Odle, Thomas R. Groves, Antiño R. Allen, Gwen V. Childs, Steven W. Barger
Neurobiol Aging. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: Neurobiol Aging. 2021 Jan; 97: 73–88. Published online 2020 Oct 10. doi: 10.1016/j.neurobiolaging.2020.10.001
PMCID:
PMC7736209
AbstractArticlePDF–1.8M
10.
GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes
Dequina A. Nicholas, Vashti S. Knight, Karen J. Tonsfeldt, Tomohiro Terasaka, Olivia Molinar-Inglis, Shannon B. Z. Stephens, JoAnn Trejo, Alexander S. Kauffman, Pamela L. Mellon, Mark A. Lawson
Sci Rep. 2020; 10: 13063. Published online 2020 Aug 3. doi: 10.1038/s41598-020-69913-z
PMCID:
PMC7400764
AbstractArticlePDF–2.9M
11.
GLUT1-dependent glycolysis regulates exacerbation of fibrosis via AIM2 inflammasome activation
Soo Jung Cho, Jong-Seok Moon, Kiichi Nikahira, Ha Seon Yun, Rebecca Harris, Kyung Sook Hong, Huarong Huang, Augustine M K Choi, Heather Stout-Delgado
Thorax. 2020 Mar; 75(3): 227–236. Published online 2019 Dec 10. doi: 10.1136/thoraxjnl-2019-213571
PMCID:
PMC7063401
AbstractArticlePDF–3.5M
12.
A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain
Tamio Furuse, Hiroshi Mizuma, Yuuki Hirose, Tomoko Kushida, Ikuko Yamada, Ikuo Miura, Hiroshi Masuya, Hiromasa Funato, Masashi Yanagisawa, Hirotaka Onoe, Shigeharu Wakana
Dis Model Mech. 2019 Sep 1; 12(9): dmm038828. Published online 2019 Sep 12. doi: 10.1242/dmm.038828
PMCID:
PMC6765196
AbstractArticle
13.
Modulating GLUT1 expression in retinal pigment epithelium decreases glucose levels in the retina: impact on photoreceptors and Müller glial cells
Aditi Swarup, Ivy S. Samuels, Brent A. Bell, John Y. S. Han, Jianhai Du, Erik Massenzio, E. Dale Abel, Kathleen Boesze-Battaglia, Neal S. Peachey, Nancy J. Philp
Am J Physiol Cell Physiol. 2019 Jan 1; 316(1): C121–C133. Published online 2018 Nov 21. doi: 10.1152/ajpcell.00410.2018
PMCID:
PMC6383144
AbstractArticle
14.
Differential Glucose Requirement in Skin Homeostasis and Injury Identifies a Therapeutic Target for Psoriasis
Zhuzhen Zhang, Zhenzhen Zi, Eunice E. Lee, Jiawei Zhao, Diana C. Contreras, Andrew P. South, E. Dale Abel, Benjamin F. Chong, Travis Vandergriff, Gregory A. Hosler, Philipp E. Scherer, Marcel Mettlen, Jeffrey C. Rathmell, Ralph J. DeBerardinis, Richard C. Wang
Nat Med. Author manuscript; available in PMC 2018 Oct 16.
Published in final edited form as: Nat Med. 2018 May; 24(5): 617–627. Published online 2018 Apr 16. doi: 10.1038/s41591-018-0003-0
PMCID:
PMC6095711
AbstractArticlePDF–3.7M
15.
Glucose Transporter 1–Dependent Glycolysis Is Increased during Aging-Related Lung Fibrosis, and Phloretin Inhibits Lung Fibrosis
Soo Jung Cho, Jong-Seok Moon, Chang-Min Lee, Augustine M. K. Choi, Heather W. Stout-Delgado
Am J Respir Cell Mol Biol. 2017 Apr; 56(4): 521–531. doi: 10.1165/rcmb.2016-0225OC
PMCID:
PMC5449513
AbstractArticlePDF–1.5M
16.
Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein
Maoxue Tang, Guangping Gao, Carlos B. Rueda, Hang Yu, David N. Thibodeaux, Tomoyuki Awano, Kristin M. Engelstad, Maria-Jose Sanchez-Quintero, Hong Yang, Fanghua Li, Huapeng Li, Qin Su, Kara E. Shetler, Lynne Jones, Ryan Seo, Jonathan McConathy, Elizabeth M. Hillman, Jeffrey L. Noebels, Darryl C. De Vivo, Umrao R. Monani
Nat Commun. 2017; 8: 14152. Published online 2017 Jan 20. doi: 10.1038/ncomms14152
PMCID:
PMC5263887
AbstractArticlePDF–2.2M
17.
Alkaline pH activates the transport activity of GLUT1in L929 fibroblast cells
Stephen M. Gunnink, Samuel A. Kerk, Benjamin D. Kuiper, Ola D. Alabi, David P. Kuipers, Riemer C. Praamsma, Kathryn E. Wrobel, Larry L. Louters
Biochimie. Author manuscript; available in PMC 2016 Aug 29.
Published in final edited form as: Biochimie. 2014 Apr; 99: 189–194. Published online 2013 Dec 12. doi: 10.1016/j.biochi.2013.12.003
PMCID:
PMC5003085
AbstractArticlePDF–529K
18.
AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival
Rigel J. Kishton, Carson E. Barnes, Amanda G. Nichols, Sivan Cohen, Valerie A. Gerriets, Peter J. Siska, Andrew N. Macintyre, Pankuri Goraksha-Hicks, Aguirre A. de Cubas, Tingyu Liu, Marc O. Warmoes, E. Dale Abel, Allen Eng Juh Yeoh, Timothy R. Gershon, W. Kimryn Rathmell, Kristy L. Richards, Jason W. Locasale, Jeffrey C. Rathmell
Cell Metab. Author manuscript; available in PMC 2017 Apr 12.
Published in final edited form as: Cell Metab. 2016 Apr 12; 23(4): 649–662. doi: 10.1016/j.cmet.2016.03.008
PMCID:
PMC4832577
AbstractArticlePDF–2.3M
19.
GLUT1 reductions exacerbate Alzheimer's disease vasculoneuronal dysfunction and degeneration
Ethan A. Winkler, Yoichiro Nishida, Abhay P. Sagare, Sanket V. Rege, Robert D. Bell, David Perlmutter, Jesse D. Sengillo, Sara Hillman, Pan Kong, Amy R. Nelson, John S. Sullivan, Zhen Zhao, Herbert J. Meiselman, Rosalinda B. Wendy, Jamie Soto, E. Dale Abel, Jacob Makshanoff, Edward Zuniga, Darryl C. De Vivo, Berislav V. Zlokovic
Nat Neurosci. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Nat Neurosci. 2015 Apr; 18(4): 521–530. Published online 2015 Mar 2. doi: 10.1038/nn.3966
PMCID:
PMC4734893
AbstractArticlePDF–2.9M
20.
Automated Protein Localization of Blood Brain Barrier Vasculature in Brightfield IHC Images
Rajath E. Soans, Diane C. Lim, Brendan T. Keenan, Allan I. Pack, James A. Shackleford
PLoS One. 2016; 11(2): e0148411. Published online 2016 Feb 1. doi: 10.1371/journal.pone.0148411
PMCID:
PMC4734698
AbstractArticlePDF–9.2M

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