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Select item 111897701.

Transglutaminase 2 knockout mice are protected from bleomycin‐induced lung fibrosis with preserved lung function and reduced metabolic derangements

Margaret A. T. Freeberg, Thomas H. Thatcher, Sarah V. Camus, Linghong Huang, John Atkinson, Wade Narrow, Jeannie Haak, Andrew M. Dylag, L. Ashley Cowart, Timothy S. Johnson, Patricia J. Sime

Physiol Rep. 2024 Jun; 12(12): e16012. Published online 2024 Jun 20. doi: 10.14814/phy2.16012

PMCID:: PMC11189770

Abstract Article PDF–22M

Select item 104871462.

Increased Osteoclastogenesis in Absence of TG2 Is Reversed by Transglutaminase Inhibition—Evidence for the Role for TG1 in Osteoclast Formation

Sahar Ebrahimi Samani, Mari T. Kaartinen

Cells. 2023 Sep; 12(17): 2139. Published online 2023 Aug 24. doi: 10.3390/cells12172139

PMCID:: PMC10487146

Abstract Article PDF–27M

Select item 103802753.

Transglutaminase 2 Facilitates Murine Wound Healing in a Strain-Dependent Manner

Ting W. Yiu, Sara R. Holman, Xenia Kaidonis, Robert M. Graham, Siiri E. Iismaa

Int J Mol Sci. 2023 Jul; 24(14): 11475. Published online 2023 Jul 14. doi: 10.3390/ijms241411475

PMCID:: PMC10380275

Abstract Article PDF–7.3M

Select item 102882734.

Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation

Zhuo Yang, Xiao‐Wen Zhang, Fang‐Fang Zhuo, Ting‐Ting Liu, Qian‐Wei Luo, Yong‐Zhe Zheng, Ling Li, Heng Yang, Yi‐Chi Zhang, Yan‐Hang Wang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng

Adv Sci (Weinh) 2023 Jun; 10(18): 2206533. Published online 2023 Apr 23. doi: 10.1002/advs.202206533

PMCID:: PMC10288273

Abstract Article PDF–5.3M

Select item 100947095.

Deletion of Transglutaminase 2 from Mouse Astrocytes Significantly Improves Their Ability to Promote Neurite Outgrowth on an Inhibitory Matrix

Jacen Emerson, Thomas Delgado, Peter Girardi, Gail V. W. Johnson

Int J Mol Sci. 2023 Apr; 24(7): 6058. Published online 2023 Mar 23. doi: 10.3390/ijms24076058

PMCID:: PMC10094709

Abstract Article PDF–3.2M

Select item 99805896.

SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes

Wang Zheng, Qianping Chen, Hongxia Liu, Liang Zeng, Yuchuan Zhou, Xinglong Liu, Yang Bai, Jianghong Zhang, Yan Pan, Chunlin Shao

Autophagy. 2023; 19(3): 839–857. Published online 2022 Aug 1. doi: 10.1080/15548627.2022.2105562

PMCID:: PMC9980589

Abstract Article PDF–6.1M

Select item 99541007.

The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury

Ruo-Xi Shi, Cong Liu, Ya-Jie Xu, Ying-Ying Wang, Bao-Dong He, Xuan-Cheng He, Hong-Zhen Du, Baoyang Hu, Jianwei Jiao, Chang-Mei Liu, Zhao-Qian Teng

Cells. 2023 Feb; 12(4): 558. Published online 2023 Feb 9. doi: 10.3390/cells12040558

PMCID:: PMC9954100

Abstract Article PDF–27M

Select item 96754538.

Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells

Katharina Thomas, Lisa Zondler, Nadine Ludwig, Marina Kardell, Corinna Lüneburg, Katharina Henke, Sina Mersmann, Andreas Margraf, Tilmann Spieker, Tobias Tekath, Ana Velic, Richard Holtmeier, Juliane Hermann, Vera Jankowski, Melanie Meersch, Dietmar Vestweber, Martin Westphal, Johannes Roth, Michael A. Schäfers, John A. Kellum, Clifford A. Lowell, Jan Rossaint, Alexander Zarbock

JCI Insight. 2022 Nov 8; 7(21): e163161. Published online 2022 Nov 8. doi: 10.1172/jci.insight.163161

PMCID:: PMC9675453

Abstract Article PDF–14M

Select item 93676859.

Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation

Aїsha Callebaut, Ylke Bruggeman, Cloé Zamit, Fernanda Marques Câmara Sodré, Magali Irla, Chantal Mathieu, Mijke Buitinga, Lut Overbergh

Front Endocrinol (Lausanne) 2022; 13: 908248. Published online 2022 Jul 26. doi: 10.3389/fendo.2022.908248

PMCID:: PMC9367685

Abstract Article PDF–3.4M

Select item 930422610.

Absence of tissue transglutaminase reduces amyloid‐beta pathology in APP23 mice

Micha M. M. Wilhelmus, Osoul Chouchane, Maarten Loos, Cornelis A. M. Jongenelen, John J. P. Brevé, Allert Jonker, John G. J. M. Bol, August B. Smit, Benjamin Drukarch

Neuropathol Appl Neurobiol. 2022 Jun; 48(4): e12796. Published online 2022 Feb 23. doi: 10.1111/nan.12796

PMCID:: PMC9304226

Abstract Article PDF–20M

Select item 903511211.

Cross-linking by tissue transglutaminase-2 alters fibrinogen-directed macrophage proinflammatory activity

Lauren G. Poole, Anna K. Kopec, Matthew J. Flick, James P. Luyendyk

J Thromb Haemost. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: J Thromb Haemost. 2022 May; 20(5): 1182–1192. Published online 2022 Feb 27. doi: 10.1111/jth.15670

PMCID:: PMC9035112

Abstract Article PDF–1.1M

Select item 877547112.

Midazolam Ameliorates Hyperglycemia-Induced Glomerular Endothelial Dysfunction by Inhibiting Transglutaminase 2 in Diabetes

Jae-Ah Seo, Nilofar Danishmalik Sayyed, Yeon-Ju Lee, Hye-Yoon Jeon, Eun-Bin Kim, Seok-Ho Hong, Soyeon Cho, Minsoo Kim, Kwon-Soo Ha

Int J Mol Sci. 2022 Jan; 23(2): 753. Published online 2022 Jan 11. doi: 10.3390/ijms23020753

PMCID:: PMC8775471

Abstract Article PDF–3.3M

Select item 862365413.

Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice

Zsófia Budai, Nour Al-Zaeed, Péter Szentesi, Hajnalka Halász, László Csernoch, Zsuzsa Szondy, Zsolt Sarang

Cells. 2021 Nov; 10(11): 3089. Published online 2021 Nov 9. doi: 10.3390/cells10113089

PMCID:: PMC8623654

Abstract Article PDF–4.3M

Select item 861611714.

Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury

Anissa Elahi, Jacen Emerson, Jacob Rudlong, Jeffrey W. Keillor, Garrick Salois, Adam Visca, Peter Girardi, Gail V.W. Johnson, Christoph Pröschel

Cells. 2021 Nov; 10(11): 2942. Published online 2021 Oct 29. doi: 10.3390/cells10112942

PMCID:: PMC8616117

Abstract Article PDF–4.6M

Select item 856574315.

TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease

Christian B. Lindstad, Alisa E. Dewan, Jorunn Stamnaes, Ludvig M. Sollid, M. Fleur du Pré

PLoS One. 2021; 16(11): e0259082. Published online 2021 Nov 3. doi: 10.1371/journal.pone.0259082

PMCID:: PMC8565743

Abstract Article PDF–1.5M

Select item 832209116.

Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2-C277S mouse model

Huilei Wang, James Chen, Sandeep Jandu, Sean Melucci, William Savage, Kavitha Nandakumar, Sara K. Kang, Sebastian Barreto-Ortiz, Alan Poe, Shivam Rastogi, Maria Bauer, Jochen Steppan, Lakshmi Santhanam

Cell Death Discov. 2021; 7: 197. Published online 2021 Jul 29. doi: 10.1038/s41420-021-00543-8