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Select item 64653971.

TRAF2 protects against cerebral ischemia-induced brain injury by suppressing necroptosis

Jie Li, Jingyu Zhang, Yusuo Zhang, Zichuang Wang, Yanmei Song, Shanwen Wei, Meijun He, Shoujiang You, Jia Jia, Jian Cheng

Cell Death Dis. 2019 May; 10(5): 328. Published online 2019 Apr 15. doi: 10.1038/s41419-019-1558-5

PMCID:: PMC6465397

Abstract Article PDF–4.9M

Select item 43541512.

Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function

A. T. Y. Yeung, C. Hale, J. Xia, P. H. Tate, D. Goulding, J. A. Keane, S. Mukhopadhyay, L. Forrester, O. Billker, W. C. Skarnes, R. E. W. Hancock, G. Dougan

Sci Rep. 2015; 5: 8908. Published online 2015 Mar 10. doi: 10.1038/srep08908

PMCID:: PMC4354151

Abstract Article PDF–1.4M

Select item 32828163.

Hepatic TRAF2 Regulates Glucose Metabolism Through Enhancing Glucagon Responses

Zheng Chen, Liang Sheng, Hong Shen, Yujun Zhao, Shaomeng Wang, Robert Brink, Liangyou Rui

Diabetes. 2012 Mar; 61(3): 566–573. Published online 2012 Feb 13. doi: 10.2337/db11-0474

PMCID:: PMC3282816

Abstract Article PDF–2.0M

Select item 27304564.

TRAF2 Suppresses Basal IKK Activity in Resting Cells and TNFα can Activate IKK in TRAF2 and TRAF5 Double Knockout Cells

Laiqun Zhang, Ken Blackwell, Gregory S. Thomas, Shujie Sun, Wen-Chen Yeh, Hasem Habelhah

J Mol Biol. Author manuscript; available in PMC 2010 Jun 12.

Published in final edited form as: J Mol Biol. 2009 Jun 12; 389(3): 495–510. Published online 2009 May 3. doi: 10.1016/j.jmb.2009.04.054

PMCID:: PMC2730456

Abstract Article PDF–1.8M

Select item 90726785.

TRIM47 is a novel endothelial activation factor that aggravates lipopolysaccharide-induced acute lung injury in mice via K63-linked ubiquitination of TRAF2

Yisong Qian, Ziwei Wang, Hongru Lin, Tianhua Lei, Zhou Zhou, Weilu Huang, Xuehan Wu, Li Zuo, Jie Wu, Yu Liu, Ling-Fang Wang, Xiao-Hui Guan, Ke-Yu Deng, Mingui Fu, Hong-Bo Xin

Signal Transduct Target Ther. 2022; 7: 148. Published online 2022 May 6. doi: 10.1038/s41392-022-00953-9

PMCID:: PMC9072678

Abstract Article PDF–5.6M

Select item 58211736.

TNF receptor–activated factor 2 mediates cardiac protection through noncanonical NF-κB signaling

Sarah Evans, Huei-Ping Tzeng, Deborah J. Veis, Scot Matkovich, Carla Weinheimer, Attila Kovacs, Philip M. Barger, Douglas L. Mann

JCI Insight. 2018 Feb 8; 3(3): e98278. Published online 2018 Feb 8. doi: 10.1172/jci.insight.98278

PMCID:: PMC5821173

Abstract Article PDF–5.3M

Select item 36750357.

Shigella IpaH0722 E3 Ubiquitin Ligase Effector Targets TRAF2 to Inhibit PKC–NF-κB Activity in Invaded Epithelial Cells

Hiroshi Ashida, Hiroyasu Nakano, Chihiro Sasakawa

PLoS Pathog. 2013 Jun; 9(6): e1003409. Published online 2013 Jun 6. doi: 10.1371/journal.ppat.1003409

PMCID:: PMC3675035

Abstract Article PDF–2.2M

Select item 35269758.

TRAF2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice

Gema Pérez-Chacón, David Llobet, Constanza Pardo, Jose Pindado, Yongwon Choi, John C. Reed, Juan M. Zapata

J Immunol. Author manuscript; available in PMC 2013 Jul 15.

Published in final edited form as: J Immunol. 2012 Jul 15; 189(2): 1053–1061. Published online 2012 Jun 18. doi: 10.4049/jimmunol.1200814

PMCID:: PMC3526975

Abstract Article PDF–1.2M

Select item 28017729.

TRAF2-MLK3 interaction is essential for TNF-a-induced MLK3 activation

Gautam Sondarva, Chanakya N. Kundu, Suneet Mehrotra, Rajakishore Mishra, Velusamy Rangasamy, Pradeep Sathyanarayana, Rajarshi S. Ray, Basabi Rana, Ajay Rana

Cell Res. Author manuscript; available in PMC 2010 Jul 1.

Published in final edited form as: Cell Res. 2010 Jan; 20(1): 89–98. Published online 2009 Nov 17. doi: 10.1038/cr.2009.125

PMCID:: PMC2801772

Abstract Article PDF–789K

Select item 278249210.

Osteoclast Inhibitory Peptide-1 (OIP-1) Inhibits Measles Virus Nucleocapsid Protein Stimulated Osteoclast Formation/Activity

Srinivasan Shanmugarajan, Rimon F. Youssef, Parmita Pati, William L. Ries, D. Sudhaker Rao, Sakamuri V. Reddy

J Cell Biochem. Author manuscript; available in PMC 2009 Nov 25.

Published in final edited form as: J Cell Biochem. 2008 Jul 1; 104(4): 1500–1508. doi: 10.1002/jcb.21723

PMCID:: PMC2782492

Abstract Article PDF–1.8M

Select item 232420411.

High Distribution of CD40 and TRAF2 in Th40 T Cell Rafts Leads to Preferential Survival of this Auto-Aggressive Population in Autoimmunity

Gisela M. Vaitaitis, David H. Wagner, Jr.

PLoS One. 2008; 3(4): e2076. Published online 2008 Apr 30. doi: 10.1371/journal.pone.0002076

PMCID:: PMC2324204

Abstract Article PDF–910K

Select item 219402312.

Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling

Joseph R. Arron, Yael Pewzner-Jung, Matthew C. Walsh, Takashi Kobayashi, Yongwon Choi

J Exp Med. 2002 Oct 7; 196(7): 923–934. doi: 10.1084/jem.20020774

PMCID:: PMC2194023

Abstract Article PDF–303K

Select item 189611313.

The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation

Li-Fan Lu, Cory L. Ahonen, Evan F. Lind, Vanitha S. Raman, W. James Cook, Ling-Li Lin, Randolph J. Noelle

Blood. 2007 Jul 1; 110(1): 193–200. Prepublished online 2007 Mar 14. doi: 10.1182/blood-2006-07-038414

PMCID:: PMC1896113

Abstract Article

Select item 53451214.

TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice

Juan M. Zapata, Maryla Krajewska, Herbert C. Morse, III, Yongwon Choi, John C. Reed

Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47): 16600–16605. Published online 2004 Nov 15. doi: 10.1073/pnas.0407541101

PMCID:: PMC534512

Abstract Article PDF–707K

Select item 48089015.

Essential Roles of Receptor-Interacting Protein and TRAF2 in Oxidative Stress-Induced Cell Death

Han-Ming Shen, Yong Lin, Swati Choksi, Jamie Tran, Tian Jin, Lufen Chang, Michael Karin, Jianke Zhang, Zheng-gang Liu

Mol Cell Biol. 2004 Jul; 24(13): 5914–5922. doi: 10.1128/MCB.24.13.5914-5922.2004

PMCID:: PMC480890

Abstract Article PDF–391K

Select item 16634416.

TRAF2 Exerts Its Antiapoptotic Effect by Regulating the Expression of Krüppel-Like Factor LKLF

Yong Lin, Jennifer Ryan, Joseph Lewis, Maqsood A. Wani, Jerry B. Lingrel, Zheng-gang Liu

Mol Cell Biol. 2003 Aug; 23(16): 5849–5856. doi: 10.1128/MCB.23.16.5849-5856.2003

PMCID:: PMC166344

Abstract Article PDF–283K

Select item 624681417.

TRAF2 deficiency in B cells impairs CD40-induced isotype-switching that can be rescued by restoring NF-κB1 activation

Rachel A Woolaver, Xiaoguang Wang, Yonatan Dollin, Ping Xie, Jing H. Wang, Zhangguo Chen

J Immunol. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: J Immunol. 2018 Dec 1; 201(11): 3421–3430. Published online 2018 Oct 19. doi: 10.4049/jimmunol.1800337

PMCID:: PMC6246814

Abstract Article PDF–977K

Select item 556849418.

Cardioprotective Role of TRAF2 by Suppressing Apoptosis and Necroptosis

Xiaoyun Guo, Haifeng Yin, Lei Li, Yi Chen, Jing Li, Jessica Doan, Rachel Steinmetz, Qinghang Liu

Circulation. Author manuscript; available in PMC 2018 Aug 22.

Published in final edited form as: Circulation. 2017 Aug 22; 136(8): 729–742. Published online 2017 Jun 1. doi: 10.1161/CIRCULATIONAHA.116.026240

PMCID:: PMC5568494

Abstract Article PDF–3.9M

Select item 485272119.

TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice

Laiqun Zhang, Ken Blackwell, Lauren M. Workman, Katherine N. Gibson-Corley, Alicia K. Olivier, Gail A. Bishop, Hasem Habelhah

J Cell Sci. 2016 Apr 1; 129(7): 1455–1467. doi: 10.1242/jcs.180554

PMCID:: PMC4852721

Abstract Article

Select item 476915820.

TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1

Nima Etemadi, Michael Chopin, Holly Anderton, Maria C Tanzer, James A Rickard, Waruni Abeysekera, Cathrine Hall, Sukhdeep K Spall, Bing Wang, Yuquan Xiong, Timothy Hla, Stuart M Pitson, Claudine S Bonder, Wendy Wei-Lynn Wong, Matthias Ernst, Gordon K Smyth, David L Vaux, Stephen L Nutt, Ueli Nachbur, John Silke

eLife. 2015; 4: e10592. Published online 2015 Dec 23. doi: 10.7554/eLife.10592