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Select item 64686011.

The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance

Sathish K. Murali, Takwa S. Aroankins, Hanne B. Moeller, Robert A. Fenton

Cells. 2019 Mar; 8(3): 265. Published online 2019 Mar 21. doi: 10.3390/cells8030265

PMCID:: PMC6468601

Article PDF–2.1M

Select item 61289472.

USP4 positively regulates RLR-induced NF-κB activation by targeting TRAF6 for K48-linked deubiquitination and inhibits enterovirus 71 replication

Chao Xu, Yang Peng, Qin Zhang, Xiao-Peng Xu, Xiang-Min Kong, Wei-Feng Shi

Sci Rep. 2018; 8: 13418. Published online 2018 Sep 7. doi: 10.1038/s41598-018-31734-6

Correction in:: Sci Rep. 2023; 13: 11670.

PMCID:: PMC6128947

Article PDF–3.2M

Select item 31176463.

USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1

Xinna Zhang, Franklin G Berger, Jianhua Yang, Xiongbin Lu

EMBO J. 2011 Jun 1; 30(11): 2177–2189. Published online 2011 Apr 26. doi: 10.1038/emboj.2011.125

PMCID:: PMC3117646

Article PDF–1.2M

Select item 107452004.

FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis

Jing Xu, Rongtian Guo, Nasi Wen, Luping Li, Yong Yi, Jingzhen Chen, Zongyu He, Jian Yang, Zhi-Xiong Jim Xiao, Mengmeng Niu

PLoS Biol. 2023 Dec; 21(12): e3002446. Published online 2023 Dec 22. doi: 10.1371/journal.pbio.3002446

PMCID:: PMC10745200

Article PDF–3.2M

Select item 46241875.

Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11

Caitlyn Vlasschaert, Xuhua Xia, Josée Coulombe, Douglas A. Gray

BMC Evol Biol. 2015; 15: 230. Published online 2015 Oct 26. doi: 10.1186/s12862-015-0511-1

PMCID:: PMC4624187

Article PDF–3.0M

Select item 33228336.

Ubiquitin-specific Protease 4 Mitigates Toll-like/Interleukin-1 Receptor Signaling and Regulates Innate Immune Activation

FangFang Zhou, Xiaofei Zhang, Hans van Dam, Peter ten Dijke, Huizhe Huang, Long Zhang

J Biol Chem. 2012 Mar 30; 287(14): 11002–11010. Published online 2012 Jan 19. doi: 10.1074/jbc.M111.328187

PMCID:: PMC3322833

Article PDF–2.6M

Select item 63559287.

Ubiquitination of Rheb governs growth factor-induced mTORC1 activation

Lu Deng, Lei Chen, Linlin Zhao, Yan Xu, Xiaoping Peng, Xinbo Wang, Lin Ding, Jiali Jin, Hongqi Teng, Yanming Wang, Weijuan Pan, Fei Yu, Lujian Liao, Li Li, Xin Ge, Ping Wang

Cell Res. 2019 Feb; 29(2): 136–150. Published online 2018 Dec 4. doi: 10.1038/s41422-018-0120-9

PMCID:: PMC6355928

Article PDF–3.4M

Select item 54520378.

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling

Fangfang Zhou, Feng Xie, Ke Jin, Zhengkui Zhang, Marcello Clerici, Rui Gao, Maarten van Dinther, Titia K Sixma, Huizhe Huang, Long Zhang, Peter ten Dijke

EMBO J. 2017 Jun 1; 36(11): 1623–1639. Published online 2017 May 3. doi: 10.15252/embj.201695372

PMCID:: PMC5452037

Article PDF–5.6M

Select item 47607809.

Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

Akhee S. Jahan, Maxime Lestra, Lee Kim Swee, Ying Fan, Mart M. Lamers, Fikadu G. Tafesse, Christopher S. Theile, Eric Spooner, Roberto Bruzzone, Hidde L. Ploegh, Sumana Sanyal

Proc Natl Acad Sci U S A. 2016 Feb 9; 113(6): E705–E714. Published online 2016 Jan 25. doi: 10.1073/pnas.1521763113

PMCID:: PMC4760780

Article PDF–1.4M

Select item 722512910.

Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk

SungKyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P. Carstens

Development. 2020 Nov 1; 147(21): dev187369. Published online 2020 May 4. doi: 10.1242/dev.187369

PMCID:: PMC7225129

Article

Select item 399654211.

Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen

Kifayathullah Liakath-Ali, Valerie E. Vancollie, Emma Heath, Damian P. Smedley, Jeanne Estabel, David Sunter, Tia DiTommaso, Jacqueline K. White, Ramiro Ramirez-Solis, Ian Smyth, Karen P. Steel, Fiona M. Watt

Nat Commun. 2014 Apr 11; 5: 3540. Published online 2014 Apr 11. doi: 10.1038/ncomms4540

PMCID:: PMC3996542

Article PDF–4.0M

Select item 626277712.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Article

Select item 31068513.

Genetic Mapping of 262 Loci Derived from Expressed Sequences in a Murine Interspecific Cross Using Single-Strand Conformational Polymorphism Analysis

Kevin P. Brady, Lucy B. Rowe, Helen Her, Tamara J. Stevens, Janan Eppig, Daniel J. Sussman, James Sikela, David R. Beier

Genome Res. 1997 Nov; 7(11): 1085–1093. doi: 10.1101/gr.7.11.1085

PMCID:: PMC310685

Article PDF–334K

Select item 645951014.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Article PDF–5.1M

Select item 1030785215.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Article PDF–8.8M

Select item 1683316.

Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray

Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko

Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127

PMCID:: PMC16833

Article PDF–847K

Select item 255627017.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Article PDF–493K

Select item 1091766018.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Article PDF–1.1M

Select item 28355420.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Article PDF–481K

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