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Select item 100896581.

Retinal microvascular and neuronal pathologies probed in vivo by adaptive optical two-photon fluorescence microscopy

Qinrong Zhang, Yuhan Yang, Kevin J Cao, Wei Chen, Santosh Paidi, Chun-hong Xia, Richard H Kramer, Xiaohua Gong, Na Ji

eLife. 2023; 12: e84853. Published online 2023 Apr 11. doi: 10.7554/eLife.84853

PMCID:: PMC10089658

Abstract Article PDF–5.6M

Select item 91314202.

Soluble very low‐density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age‐related macular degeneration

Xiang Ma, Yusuke Takahashi, Wenjing Wu, Jianglei Chen, Marcus Dehdarani, Wentao Liang, Young‐Hwa Shin, Siribhinya Benyajati, Jian‐xing Ma

FASEB J. 2021 Dec; 35(12): e22058. Published online 2021 Nov 25. doi: 10.1096/fj.202101334R

PMCID:: PMC9131420

Abstract Article PDF–2.7M

Select item 80442313.

Very low-density lipoprotein receptor increases in a liver-specific manner due to protein deficiency but does not affect fatty liver in mice

Yui Oshio, Yuta Hattori, Hatsuho Kamata, Yori Ozaki-Masuzawa, Arisa Seki, Yasutaka Tsuruta, Asako Takenaka

Sci Rep. 2021; 11: 8003. Published online 2021 Apr 13. doi: 10.1038/s41598-021-87568-2

PMCID:: PMC8044231

Abstract Article PDF–1.6M

Select item 74413364.

CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

Felicitas Bucher, Edith Aguilar, Kyle V. Marra, Julian Rapp, Jakob Arnold, Sophia Diaz-Aguilar, Clemens Lange, Hansjürgen Agostini, Günther Schlunck, Andreas Stahl, Martin Friedlander

Invest Ophthalmol Vis Sci. 2020 Aug; 61(10): 20. Published online 2020 Aug 11. doi: 10.1167/iovs.61.10.20

PMCID:: PMC7441336

Abstract Article PDF–8.8M

Select item 56518115.

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

Kyung Cheul Shin, Injae Hwang, Sung Sik Choe, Jeu Park, Yul Ji, Jong In Kim, Gha Young Lee, Sung Hee Choi, Jianhong Ching, Jean-Paul Kovalik, Jae Bum Kim

Nat Commun. 2017; 8: 1087. Published online 2017 Oct 20. doi: 10.1038/s41467-017-01232-w

PMCID:: PMC5651811

Abstract Article PDF–2.2M

Select item 50534936.

Multi-Functional OCT Enables Longitudinal Study of Retinal Changes in a VLDLR Knockout Mouse Model

Marco Augustin, Stanislava Fialová, Tanja Himmel, Martin Glösmann, Theresia Lengheimer, Danielle J. Harper, Roberto Plasenzotti, Michael Pircher, Christoph K. Hitzenberger, Bernhard Baumann

PLoS One. 2016; 11(10): e0164419. Published online 2016 Oct 6. doi: 10.1371/journal.pone.0164419

PMCID:: PMC5053493

Abstract Article PDF–2.3M

Select item 47876167.

The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease

Richard L. Sidman, Jianxue Li, Matthew Lawrence, Wenzheng Hu, Gary F. Musso, Ricardo J. Giordano, Marina Cardó-Vila, Renata Pasqualini, Wadih Arap

Sci Transl Med. Author manuscript; available in PMC 2016 Mar 11.

Published in final edited form as: Sci Transl Med. 2015 Oct 14; 7(309): 309ra165. doi: 10.1126/scitranslmed.aac4882

PMCID:: PMC4787616

Abstract Article PDF–3.3M

Select item 42632908.

Nanoceria inhibit expression of genes associated with inflammation and angiogenesis in the retina of Vldlr null mice

Svetlana V. Kyosseva, Lijuan Chen, Sudipta Seal, James J. McGinnis

Exp Eye Res. Author manuscript; available in PMC 2014 Dec 11.

Published in final edited form as: Exp Eye Res. 2013 Nov; 116: 63–74. Published online 2013 Aug 24. doi: 10.1016/j.exer.2013.08.003

PMCID:: PMC4263290

Abstract Article PDF–1.6M

Select item 38943479.

Very Low Density Lipoprotein Receptor (VLDLR) Expression Is a Determinant Factor in Adipose Tissue Inflammation and Adipocyte-Macrophage Interaction

Andrew Nguyen, Huan Tao, Michael Metrione, Tahar Hajri

J Biol Chem. 2014 Jan 17; 289(3): 1688–1703. Published online 2013 Nov 29. doi: 10.1074/jbc.M113.515320

PMCID:: PMC3894347

Abstract Article PDF–3.8M

Select item 380979610.

Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting

Peter D. Westenskow, Toshihide Kurihara, Edith Aguilar, Elizabeth L. Scheppke, Stacey K. Moreno, Carli Wittgrove, Valentina Marchetti, Iacovos P. Michael, Sudarshan Anand, Andras Nagy, David Cheresh, Martin Friedlander

J Clin Invest. 2013 Nov 1; 123(11): 4900–4908. Published online 2013 Oct 1. doi: 10.1172/JCI70230

PMCID:: PMC3809796

Abstract Article PDF–6.3M

Select item 354441811.

Pathogenic Role of the Wnt Signaling Pathway Activation In Laser-Induced Choroidal Neovascularization

Yang Hu, Ying Chen, Mingkai Lin, Kyungwon Lee, Robert A. Mott, Jian-xing Ma

Invest Ophthalmol Vis Sci. 2013 Jan; 54(1): 141–154. Published online 2013 Jan 7. doi: 10.1167/iovs.12-10281

PMCID:: PMC3544418

Abstract Article PDF–543K

Select item 325702112.

Identification of VLDLR as a novel endothelial cell receptor for fibrin that modulates fibrin-dependent transendothelial migration of leukocytes

Sergiy Yakovlev, Irina Mikhailenko, Chunzhang Cao, Li Zhang, Dudley K. Strickland, Leonid Medved

Blood. 2012 Jan 12; 119(2): 637–644. Prepublished online 2011 Nov 17. doi: 10.1182/blood-2011-09-382580

PMCID:: PMC3257021

Abstract Article

Select item 322381813.

The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial infarction

Jeanna C. Perman, Pontus Boström, Malin Lindbom, Ulf Lidberg, Marcus StÅhlman, Daniel Hägg, Henrik Lindskog, Margareta Scharin Täng, Elmir Omerovic, Lillemor Mattsson Hultén, Anders Jeppsson, Petur Petursson, Johan Herlitz, Gunilla Olivecrona, Dudley K. Strickland, Kim Ekroos, Sven-Olof Olofsson, Jan Borén

J Clin Invest. 2011 Jul 1; 121(7): 2625–2640. Published online 2011 Jun 13. doi: 10.1172/JCI43068

PMCID:: PMC3223818

Abstract Article PDF–2.3M

Select item 317602814.

The Role of Vldlr in Intraretinal Angiogenesis in Mice

Chun-hong Xia, Eric Lu, Haiquan Liu, Xin Du, Bruce Beutler, Xiaohua Gong

Invest Ophthalmol Vis Sci. 2011 Aug; 52(9): 6572–6579. Published online 2011 Aug 22. doi: 10.1167/iovs.10-7082

PMCID:: PMC3176028

Abstract Article PDF–3.1M

Select item 308856315.

Resveratrol Inhibits Pathologic Retinal Neovascularization in Vldlr^−/−Mice

Jing Hua, Karen I. Guerin, Jing Chen, Shaday Michán, Andreas Stahl, Nathan M. Krah, Molly R. Seaward, Roberta J. Dennison, Aimee M. Juan, Colman J. Hatton, Przemyslaw Sapieha, David A. Sinclair, Lois E. H. Smith

Invest Ophthalmol Vis Sci. 2011 Apr; 52(5): 2809–2816. Published online 2011 Apr 25. doi: 10.1167/iovs.10-6496

PMCID:: PMC3088563

Abstract Article PDF–1.3M

Select item 304306316.

Nanoceria Inhibit the Development and Promote the Regression of Pathologic Retinal Neovascularization in the Vldlr Knockout Mouse

Xiaohong Zhou, Lily L. Wong, Ajay S. Karakoti, Sudipta Seal, James F. McGinnis

PLoS One. 2011; 6(2): e16733. Published online 2011 Feb 22. doi: 10.1371/journal.pone.0016733

PMCID:: PMC3043063

Abstract Article PDF–667K

Select item 278155917.

Peroxisome Proliferator-activated Receptor γ Agonist Rosiglitazone Increases Expression of Very Low Density Lipoprotein Receptor Gene in Adipocytes

Takeshi Takazawa, Toshimasa Yamauchi, Atsushi Tsuchida, Makoto Takata, Yusuke Hada, Masato Iwabu, Miki Okada-Iwabu, Kohjiro Ueki, Takashi Kadowaki

J Biol Chem. 2009 Oct 30; 284(44): 30049–30057. Published online 2009 Aug 25. doi: 10.1074/jbc.M109.047993

PMCID:: PMC2781559

Abstract Article PDF–2.8M

Select item 272801918.

Photoreceptor Degeneration and Retinal Inflammation Induced by Very Low-density Lipoprotein Receptor Deficiency

Ying Chen, Yang Hu, Gennadiy Moiseyev, Kevin K. Zhou, Danyang Chen, Jian-xing Ma

Microvasc Res. Author manuscript; available in PMC 2009 Aug 17.

Published in final edited form as: Microvasc Res. 2009 Jun; 78(1): 119–127. Published online 2009 Mar 10. doi: 10.1016/j.mvr.2009.02.005

PMCID:: PMC2728019

Abstract Article PDF–1.1M

Select item 264867919.

Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress

Michael I. Dorrell, Edith Aguilar, Ruth Jacobson, Oscar Yanes, Ray Gariano, John Heckenlively, Eyal Banin, G. Anthony Ramirez, Mehdi Gasmi, Alan Bird, Gary Siuzdak, Martin Friedlander

J Clin Invest. 2009 Mar 2; 119(3): 611–623. Published online 2009 Feb 2. doi: 10.1172/JCI35977