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Select item 100129291.

RAB21 controls autophagy and cellular energy homeostasis by regulating retromer-mediated recycling of SLC2A1/GLUT1

Yifei Pei, Shuning Lv, Yong Shi, Jingwen Jia, Mengru Ma, Hailong Han, Rongying Zhang, Jieqiong Tan, Xinjun Zhang

Autophagy. 2023; 19(4): 1070–1086. Published online 2022 Aug 21. doi: 10.1080/15548627.2022.2114271

PMCID:: PMC10012929

Abstract Article PDF–7.0M

Select item 57355092.

Knockdown of Rab21 inhibits proliferation and induces apoptosis in human glioma cells

Jian Ge, Qianxue Chen, Baohui Liu, Long Wang, Shenqi Zhang, Baowei Ji

Cell Mol Biol Lett. 2017; 22: 30. Published online 2017 Dec 19. doi: 10.1186/s11658-017-0062-0

PMCID:: PMC5735509

Abstract Article PDF–1.5M

Select item 34199823.

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo

G Högnäs, S Tuomi, S Veltel, E Mattila, A Murumägi, H Edgren, O Kallioniemi, J Ivaska

Oncogene. 2012 Aug 2; 31(31): 3597–3606. Published online 2011 Nov 28. doi: 10.1038/onc.2011.527

PMCID:: PMC3419982

Abstract Article PDF–741K

Select item 28166494.

A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion

S Hooper, C Gaggioli, E Sahai

Br J Cancer. 2010 Jan 19; 102(2): 392–402. Published online 2009 Dec 1. doi: 10.1038/sj.bjc.6605469

PMCID:: PMC2816649

Abstract Article PDF–994K

Select item 89736205.

Circular RNA Circ_0008043 promotes the proliferation and metastasis of hepatocellular carcinoma cells by regulating the microRNA (miR)-326/RAB21 axis

Kangjun Zhang, Taishi Fang, Dong Zhao, Fulan Cen, Xu Yan, Xin Jin

Bioengineered. 2022; 13(3): 6600–6614. Published online 2022 Feb 27. doi: 10.1080/21655979.2022.2044260

PMCID:: PMC8973620

Abstract Article PDF–6.0M

Select item 88356976.

Rab21 Protein Is Degraded by Both the Ubiquitin-Proteasome Pathway and the Autophagy-Lysosome Pathway

Pinduo Liu, Anping Wu, Hui Li, Jun Zhang, Junjun Ni, Zhenzhen Quan, Hong Qing

Int J Mol Sci. 2022 Feb; 23(3): 1131. Published online 2022 Jan 20. doi: 10.3390/ijms23031131

PMCID:: PMC8835697

Abstract Article PDF–2.3M

Select item 66831717.

Colorectal cancer cells respond differentially to autophagy inhibition in vivo

Annie Lauzier, Josiann Normandeau-Guimond, Vanessa Vaillancourt-Lavigueur, Vincent Boivin, Martine Charbonneau, Nathalie Rivard, Michelle S. Scott, Claire M. Dubois, Steve Jean

Sci Rep. 2019; 9: 11316. Published online 2019 Aug 5. doi: 10.1038/s41598-019-47659-7

PMCID:: PMC6683171

Abstract Article PDF–8.2M

Select item 67773648.

RAB21 interacts with TMED10 and modulates its localization and abundance

Tomas Del Olmo, Camille Lacarrière-Keïta, Caroline Normandin, Dominique Jean, François-Michel Boisvert, Steve Jean

Biol Open. 2019 Sep 15; 8(9): bio045336. Published online 2019 Aug 27. doi: 10.1242/bio.045336

PMCID:: PMC6777364

Abstract Article PDF–2.0M

Select item 22541849.

Structural basis for Rab GTPase activation by VPS9 domain exchange factors

Anna Delprato, David G Lambright

Nat Struct Mol Biol. Author manuscript; available in PMC 2008 Feb 25.

Published in final edited form as: Nat Struct Mol Biol. 2007 May; 14(5): 406–412. Published online 2007 Apr 22. doi: 10.1038/nsmb1232

PMCID:: PMC2254184

Abstract Article PDF–3.6M

Select item 314440810.

Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration

Anja Mai, Stefan Veltel, Teijo Pellinen, Artur Padzik, Eleanor Coffey, Varpu Marjomäki, Johanna Ivaska

J Cell Biol. 2011 Jul 25; 194(2): 291–306. doi: 10.1083/jcb.201012126

PMCID:: PMC3144408

Abstract Article PDF–4.0M

Select item 193340211.

Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5

Guangyu Zhu, Jia Chen, Jay Liu, Joseph S Brunzelle, Bo Huang, Nancy Wakeham, Simon Terzyan, Xuemei Li, Zihe Rao, Guangpu Li, Xuejun C Zhang

EMBO J. 2007 Jul 25; 26(14): 3484–3493. Published online 2007 Jun 21. doi: 10.1038/sj.emboj.7601771

PMCID:: PMC1933402

Abstract Article PDF–433K

Select item 206389212.

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of β1-integrins

Teijo Pellinen, Antti Arjonen, Karoliina Vuoriluoto, Katja Kallio, Jack A.M. Fransen, Johanna Ivaska

J Cell Biol. 2006 Jun 5; 173(5): 767–780. doi: 10.1083/jcb.200509019

PMCID:: PMC2063892

Abstract Article PDF–6.4M

Select item 275973713.

Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth

Andrea Burgo, Emmanuel Sotirakis, Marie-Christine Simmler, Agathe Verraes, Christophe Chamot, Jeremy C Simpson, Letizia Lanzetti, Véronique Proux-Gillardeaux, Thierry Galli

EMBO Rep. 2009 Oct; 10(10): 1117–1124. Published online 2009 Sep 11. doi: 10.1038/embor.2009.186

PMCID:: PMC2759737

Abstract Article PDF–1.1M

Select item 436486914.

Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome–lysosome fusion

Steve Jean, Sarah Cox, Sonya Nassari, Amy A Kiger

EMBO Rep. 2015 Mar; 16(3): 297–311. Published online 2015 Feb 3. doi: 10.15252/embr.201439464

PMCID:: PMC4364869

Abstract Article PDF–1.8M

Select item 136021815.

Structural basis of family-wide Rab GTPase recognition by Rabenosyn-5

Sudharshan Eathiraj, Xiaojing Pan, Christopher J. Ritacco, David G. Lambright

Nature. Author manuscript; available in PMC 2006 Feb 2.

Published in final edited form as: Nature. 2005 Jul 21; 436(7049): 415–419. doi: 10.1038/nature03798

PMCID:: PMC1360218

Abstract Article PDF–2.5M

Select item 713853716.

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

Johanna Hietamäki, Louise C Gregory, Sandy Ayoub, Anna-Pauliina Iivonen, Kirsi Vaaralahti, Xiaonan Liu, Nina Brandstack, Andrew J Buckton, Tiina Laine, Johanna Känsäkoski, Matti Hero, Päivi J Miettinen, Markku Varjosalo, Emma Wakeling, Mehul T Dattani, Taneli Raivio

J Clin Endocrinol Metab. 2020 Jun; 105(6): 1748–1758. Published online 2020 Feb 15. doi: 10.1210/clinem/dgaa078

PMCID:: PMC7138537

Abstract Article

Select item 295846817.

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

Shin-ichiro Yoshimura, Andreas Gerondopoulos, Andrea Linford, Daniel J. Rigden, Francis A. Barr

J Cell Biol. 2010 Oct 18; 191(2): 367–381. doi: 10.1083/jcb.201008051

PMCID:: PMC2958468

Abstract Article PDF–9.0M

Select item 676993018.

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu

Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082

PMCID:: PMC6769930

Abstract Article PDF–4.3M

Select item 710529419.

STUB1 is targeted by the SUMO-interacting motif of EBNA1 to maintain Epstein-Barr Virus latency

Yuyan Wang, Shujuan Du, Caixia Zhu, Chong Wang, Nuoya Yu, Ziqi Lin, Jin Gan, Yi Guo, Xinxin Huang, Yuping He, Erle Robertson, Di Qu, Fang Wei, Qiliang Cai

PLoS Pathog. 2020 Mar; 16(3): e1008447. Published online 2020 Mar 16. doi: 10.1371/journal.ppat.1008447