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Items: 1 to 20 of 26

1.
ZnT2 Is Critical for TLR4-Mediated Cytokine Expression in Colonocytes and Modulates Mucosal Inflammation in Mice
Katherine McGourty, Ramya Vijayakumar, Tong Wu, Annie Gagnon, Shannon L. Kelleher
Int J Mol Sci. 2022 Oct; 23(19): 11467. Published online 2022 Sep 28. doi: 10.3390/ijms231911467
PMCID:
PMC9570081
AbstractArticlePDF–4.5M
2.
ZnT2 is critical for lysosome acidification and biogenesis during mammary gland involution
Olivia C. Rivera, Stephen R. Hennigar, Shannon L. Kelleher
Am J Physiol Regul Integr Comp Physiol. 2018 Aug 1; 315(2): R323–R335. Published online 2018 May 2. doi: 10.1152/ajpregu.00444.2017
PMCID:
PMC7199225
AbstractArticle
3.
Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells
Sooyeon Lee, Olivia C. Rivera, Shannon L. Kelleher
J Biol Chem. 2017 Dec 29; 292(52): 21598–21613. Published online 2017 Nov 7. doi: 10.1074/jbc.M117.794461
PMCID:
PMC5766956
AbstractArticlePDF–4.6M
4.
Essential Role for Zinc Transporter 2 (ZnT2)-mediated Zinc Transport in Mammary Gland Development and Function during Lactation
Sooyeon Lee, Stephen R. Hennigar, Samina Alam, Keigo Nishida, Shannon L. Kelleher
J Biol Chem. 2015 May 22; 290(21): 13064–13078. Published online 2015 Apr 7. doi: 10.1074/jbc.M115.637439
PMCID:
PMC4505563
AbstractArticlePDF–5.9M
5.
ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution
Stephen R. Hennigar, Young Ah Seo, Supriya Sharma, David I. Soybel, Shannon L. Kelleher
Sci Rep. 2015; 5: 8033. Published online 2015 Jan 26. doi: 10.1038/srep08033
PMCID:
PMC4306139
AbstractArticlePDF–13M
6.
Prolactin (PRL)-stimulated Ubiquitination of ZnT2 Mediates a Transient Increase in Zinc Secretion Followed by ZnT2 Degradation in Mammary Epithelial Cells
Young Ah Seo, Sooyeon Lee, Stephen R. Hennigar, Shannon L. Kelleher
J Biol Chem. 2014 Aug 22; 289(34): 23653–23661. Published online 2014 Jul 11. doi: 10.1074/jbc.M113.531145
PMCID:
PMC4156067
AbstractArticlePDF–1.0M
7.
Functional analysis of two single nucleotide polymorphisms in SLC30A2 (ZnT2): implications for mammary gland function and breast disease in women
Young Ah Seo, Shannon L. Kelleher
Physiol Genomics. 2010 Dec; 42A(4): 219–227. Published online 2010 Sep 21. doi: 10.1152/physiolgenomics.00137.2010
PMCID:
PMC3008367
AbstractArticle
8.
A genetic variant in SLC30A2 causes breast dysfunction during lactation by inducing ER stress, oxidative stress and epithelial barrier defects
Sooyeon Lee, Yandong Zhou, Donald L. Gill, Shannon L. Kelleher
Sci Rep. 2018; 8: 3542. Published online 2018 Feb 23. doi: 10.1038/s41598-018-21505-8
PMCID:
PMC5824919
AbstractArticlePDF–4.7M
9.
Zinc transporter-2 (ZnT2) variants are localized to distinct subcellular compartments and functionally transport zinc
Veronica Lopez, Shannon L. Kelleher
Biochem J. Author manuscript; available in PMC 2012 Jun 25.
Published in final edited form as: Biochem J. 2009 Jul 29; 422(1): 43–52. Published online 2009 Jul 29. doi: 10.1042/BJ20081189
PMCID:
PMC3381892
AbstractArticlePDF–2.2M
10.
A histidine-rich motif mediates mitochondrial localization of ZnT2 to modulate mitochondrial function
Young Ah Seo, Veronica Lopez, Shannon L. Kelleher
Am J Physiol Cell Physiol. 2011 Jun; 300(6): C1479–C1489. Published online 2011 Feb 2. doi: 10.1152/ajpcell.00420.2010
PMCID:
PMC3118624
AbstractArticle
11.
STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells
Liang Guo, Louis A. Lichten, Moon-Suhn Ryu, Juan P. Liuzzi, Fudi Wang, Robert J. Cousins
Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7): 2818–2823. Published online 2010 Jan 27. doi: 10.1073/pnas.0914941107
PMCID:
PMC2840329
AbstractArticlePDF–462K
12.
Responsive transporter genes within the murine intestinal-pancreatic axis form a basis of zinc homeostasis
Juan P. Liuzzi, Jeffrey A. Bobo, Louis A. Lichten, Don A. Samuelson, Robert J. Cousins
Proc Natl Acad Sci U S A. 2004 Oct 5; 101(40): 14355–14360. Published online 2004 Sep 20. doi: 10.1073/pnas.0406216101
PMCID:
PMC521973
AbstractArticlePDF–540K
13.
Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis
Keigo Nishida, Aiko Hasegawa, Satoru Yamasaki, Ryota Uchida, Wakana Ohashi, Yosuke Kurashima, Jun Kunisawa, Shunsuke Kimura, Toshihiko Iwanaga, Hiroshi Watarai, Koji Hase, Hideki Ogura, Manabu Nakayama, Jun-ichi Kashiwakura, Yoshimichi Okayama, Masato Kubo, Osamu Ohara, Hiroshi Kiyono, Haruhiko Koseki, Masaaki Murakami, Toshio Hirano
Sci Rep. 2019; 9: 10842. Published online 2019 Jul 25. doi: 10.1038/s41598-019-47132-5
PMCID:
PMC6658492
AbstractArticlePDF–1.9M
14.
Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells
Linxi Qian, Veronica Lopez, Young Ah Seo, Shannon L. Kelleher
Am J Physiol Cell Physiol. 2009 Aug; 297(2): C369–C377. Published online 2009 Jun 3. doi: 10.1152/ajpcell.00589.2008
PMCID:
PMC2724096
AbstractArticle
15.
ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration.
R D Palmiter, T B Cole, S D Findley
EMBO J. 1996 Apr 15; 15(8): 1784–1791.
PMCID:
PMC450094
SummaryPage BrowsePDF–2.0M
16.
Overview of mammalian zinc transporters
T. Kambe, Y. Yamaguchi-Iwai, R. Sasaki, M. Nagao
Cell Mol Life Sci. 2004 Jan; 61(1): 49–68. doi: 10.1007/s00018-003-3148-y
PMCID:
PMC11138893
AbstractArticlePDF–392K
17.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
18.
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko
Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127
PMCID:
PMC16833
AbstractArticlePDF–847K
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M

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