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Select item 65559971.

CYFIP1 overexpression increases fear response in mice but does not affect social or repetitive behavioral phenotypes

Catherine Fricano-Kugler, Aaron Gordon, Grace Shin, Kun Gao, Jade Nguyen, Jamee Berg, Mary Starks, Daniel H. Geschwind

Mol Autism. 2019; 10: 25. Published online 2019 Jun 7. doi: 10.1186/s13229-019-0278-0

PMCID:: PMC6555997

Abstract Article PDF–2.5M

Select item 53919252.

CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma

Piotr J. Dziunycz, Johannes Neu, Karine Lefort, Nadia Djerbi, Sandra N. Freiberger, Guergana Iotzova-Weiss, Lars E. French, Gian-Paolo Dotto, Günther F. Hofbauer

PLoS One. 2017; 12(4): e0173000. Published online 2017 Apr 14. doi: 10.1371/journal.pone.0173000

PMCID:: PMC5391925

Abstract Article PDF–1.8M

Select item 49248133.

A Common CYFIP1 Variant at the 15q11.2 Disease Locus Is Associated with Structural Variation at the Language-Related Left Supramarginal Gyrus

Young Jae Woo, Tao Wang, Tulio Guadalupe, Rebecca A. Nebel, Arianna Vino, Victor A. Del Bene, Sophie Molholm, Lars A. Ross, Marcel P. Zwiers, Simon E. Fisher, John J. Foxe, Brett S. Abrahams

PLoS One. 2016; 11(6): e0158036. Published online 2016 Jun 28. doi: 10.1371/journal.pone.0158036

PMCID:: PMC4924813

Abstract Article PDF–1.0M

Select item 47326164.

Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks

Rebecca A. Nebel, Dejian Zhao, Erika Pedrosa, Jill Kirschen, Herbert M. Lachman, Deyou Zheng, Brett S. Abrahams

PLoS One. 2016; 11(1): e0148039. Published online 2016 Jan 29. doi: 10.1371/journal.pone.0148039

PMCID:: PMC4732616

Abstract Article PDF–1.4M

Select item 42370095.

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

Ki-Jun Yoon, Ha Nam Nguyen, Gianluca Ursini, Fengyu Zhang, Nam-Shik Kim, Zhexing Wen, Georgia Makri, David Nauen, Joo Heon Shin, Youngbin Park, Raeeun Chung, Eva Pekle, Ce Zhang, Maxwell Towe, S Mohammed Qasim Hussaini, Yohan Lee, Dan Rujescu, David St. Clair, Joel E. Kleinman, Thomas M. Hyde, Gregory Krauss, Kimberly M. Christian, Judith L. Rapoport, Daniel R. Weinberger, Hongjun Song, Guo-li Ming

Cell Stem Cell. Author manuscript; available in PMC 2015 Jul 3.

Published in final edited form as: Cell Stem Cell. 2014 Jul 3; 15(1): 79–91. doi: 10.1016/j.stem.2014.05.003

Correction in:: volume 16 on page 339

PMCID:: PMC4237009

Abstract Article PDF–3.9M

Select item 27542706.

Cyfip1 is a putative invasion suppressor in epithelial cancers

Jose M. Silva, Elena Ezhkova, Javier Silva, Stephen Heart, Mireia Castillo, Yolanda Campos, Veronica Castro, Felix Bonilla, Carlos Cordon-Cardo, Senthil K. Muthuswamy, Scott Powers, Elaine Fuchs, Gregory J. Hannon

Cell. Author manuscript; available in PMC 2009 Dec 12.

Published in final edited form as: Cell. 2009 Jun 12; 137(6): 1047–1061. doi: 10.1016/j.cell.2009.04.013

PMCID:: PMC2754270

Abstract Article PDF–6.9M

Select item 109074857.

Integrated machine learning-driven disulfidptosis profiling: CYFIP1 and EMILIN1 as therapeutic nodes in neuroblastoma

Zhang Mengzhen, Hou Xinwei, Tan Zeheng, Li Nan, Yang Yang, Yang Huirong, Fan Kaisi, Ding Xiaoting, Yang Liucheng, Wu Kai

J Cancer Res Clin Oncol. 2024; 150(3): 109. Published online 2024 Mar 1. doi: 10.1007/s00432-024-05630-8

PMCID:: PMC10907485

Abstract Article PDF–16M

Select item 81444038.

Haploinsufficiency of the schizophrenia and autism risk gene Cyfip1 causes abnormal postnatal hippocampal neurogenesis through microglial and Arp2/3 mediated actin dependent mechanisms

Niels Haan, Laura J. Westacott, Jenny Carter, Michael J. Owen, William P. Gray, Jeremy Hall, Lawrence S. Wilkinson

Transl Psychiatry. 2021; 11: 313. Published online 2021 May 24. doi: 10.1038/s41398-021-01415-6

PMCID:: PMC8144403

Abstract Article PDF–3.0M

Select item 66797469.

Domain-specific cognitive impairments in humans and flies with reduced CYFIP1 dosage

Young Jae Woo, Alexandras K. Kanellopoulos, Parisa Hemati, Jill Kirschen, Rebecca A. Nebel, Tao Wang, Claudia Bagni, Brett S. Abrahams

Biol Psychiatry. Author manuscript; available in PMC 2020 Aug 15.

Published in final edited form as: Biol Psychiatry. 2019 Aug 15; 86(4): 306–314. Published online 2019 Apr 17. doi: 10.1016/j.biopsych.2019.04.008

PMCID:: PMC6679746

Abstract Article PDF–1015K

Select item 561456510.

Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites

Baoyu Chen, Hui-Ting Chou, Chad A Brautigam, Wenmin Xing, Sheng Yang, Lisa Henry, Lynda K Doolittle, Thomas Walz, Michael K Rosen

eLife. 2017; 6: e29795. Published online 2017 Sep 26. doi: 10.7554/eLife.29795

PMCID:: PMC5614565

Abstract Article PDF–6.1M

Select item 440949811.

Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR

A Oguro-Ando, C Rosensweig, E Herman, Y Nishimura, D Werling, BR Bill, JM Berg, F Gao, G Coppola, BS Abrahams, DH Geschwind

Mol Psychiatry. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Mol Psychiatry. 2015 Sep; 20(9): 1069–1078. Published online 2014 Oct 14. doi: 10.1038/mp.2014.124

PMCID:: PMC4409498

Abstract Article PDF–960K

Select item 606249812.

Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7–CYFIP1-mediated signaling pathway

Jer-Wei Chang, Wen-Hung Kuo, Chiao-Mei Lin, Wen-Ling Chen, Shih-Hsuan Chan, Meng-Fan Chiu, I-Shou Chang, Shih-Sheng Jiang, Fang-Yu Tsai, Chung-Hsing Chen, Pei-Hsin Huang, King-Jen Chang, Kai-Ti Lin, Sheng-Chieh Lin, Ming-Yang Wang, Yih-Huei Uen, Chi-Wen Tu, Ming-Feng Hou, Shih-Feng Tsai, Chen-Yang Shen, Shiao-Lin Tung, Lu-Hai Wang

Oncogene. 2018; 37(30): 4137–4150. Published online 2018 Apr 30. doi: 10.1038/s41388-018-0253-9

PMCID:: PMC6062498

Abstract Article PDF–2.7M

Select item 501046913.

The WASF3-NCKAP1-CYFIP1 complex is essential for breast cancer metastasis

Yong Teng, Haiyan Qin, Abdulaziz Bahassan, N George Bendzunas, Eileen J Kennedy, John Cowell

Cancer Res. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Cancer Res. 2016 Sep 1; 76(17): 5133–5142. Published online 2016 Jul 18. doi: 10.1158/0008-5472.CAN-16-0562

PMCID:: PMC5010469

Abstract Article PDF–2.8M

Select item 473777014.

Cyfip1 Regulates Presynaptic Activity during Development

Kuangfu Hsiao, Hala Harony-Nicolas, Joseph D. Buxbaum, Ozlem Bozdagi-Gunal, Deanna L. Benson

J Neurosci. 2016 Feb 3; 36(5): 1564–1576. doi: 10.1523/JNEUROSCI.0511-15.2016

PMCID:: PMC4737770

Abstract Article PDF–3.1M

Select item 545379915.

Expression of 4 Genes Between Chromosome 15 Breakpoints 1 and 2 and Behavioral Outcomes in Prader-Willi Syndrome

Douglas C. Bittel, Nataliya Kibiryeva, Merlin G. Butler

Pediatrics. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Pediatrics. 2006 Oct; 118(4): e1276–e1283. Published online 2006 Sep 18. doi: 10.1542/peds.2006-0424

PMCID:: PMC5453799

Abstract Article PDF–641K

Select item 324150916.

Protein complexes containing CYFIP/Sra/PIR121 coordinate ARF1 and RAC1 signaling during clathrin-AP-1-coated carrier biogenesis at the TGN

Mihaela ANITEI, Christoph STANGE, Irina PARSHINA, Thorsten BAUST, Annette SCHENCK, Graça RAPOSO, Tomas KIRCHHAUSEN, Bernard HOFLACK

Nat Cell Biol. Author manuscript; available in PMC 2011 Dec 16.

Published in final edited form as: Nat Cell Biol. 2010 Apr; 12(4): 330–340. Published online 2010 Mar 14. doi: 10.1038/ncb2034

Correction in:: volume 12 on page 520

PMCID:: PMC3241509

Abstract Article PDF–4.1M

Select item 539956217.

New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes

Sabiha Abekhoukh, H. Bahar Sahin, Mauro Grossi, Samantha Zongaro, Thomas Maurin, Irene Madrigal, Daniele Kazue-Sugioka, Annick Raas-Rothschild, Mohamed Doulazmi, Pilar Carrera, Andrea Stachon, Steven Scherer, Maria Rita Drula Do Nascimento, Alain Trembleau, Ignacio Arroyo, Peter Szatmari, Isabel M. Smith, Montserrat Milà, Adam C. Smith, Angela Giangrande, Isabelle Caillé, Barbara Bardoni

Dis Model Mech. 2017 Apr 1; 10(4): 463–474. doi: 10.1242/dmm.025809

PMCID:: PMC5399562

Abstract Article

Select item 271665818.

The WAVE Regulatory Complex is Inhibited

Ayman M. Ismail, Shae B. Padrick, Baoyu Chen, Junko Umetani, Michael K. Rosen

Nat Struct Mol Biol. Author manuscript; available in PMC 2009 Nov 1.

Published in final edited form as: Nat Struct Mol Biol. 2009 May; 16(5): 561–563. Published online 2009 Apr 12. doi: 10.1038/nsmb.1587

PMCID:: PMC2716658

Abstract Article PDF–797K

Select item 128024819.

CRMP-2 Is Involved in Kinesin-1-Dependent Transport of the Sra-1/WAVE1 Complex and Axon Formation

Yoji Kawano, Takeshi Yoshimura, Daisuke Tsuboi, Saeko Kawabata, Takako Kaneko-Kawano, Hiromichi Shirataki, Tadaomi Takenawa, Kozo Kaibuchi

Mol Cell Biol. 2005 Nov; 25(22): 9920–9935. doi: 10.1128/MCB.25.22.9920-9935.2005

PMCID:: PMC1280248

Abstract Article PDF–1.6M

Select item 118061120.

Identification of Four Highly Conserved Genes between Breakpoint Hotspots BP1 and BP2 of the Prader-Willi/Angelman Syndromes Deletion Region That Have Undergone Evolutionary Transposition Mediated by Flanking Duplicons

J-H. Chai, D. P. Locke, J. M. Greally, J. H. M. Knoll, T. Ohta, J. Dunai, A. Yavor, E. E. Eichler, R. D. Nicholls

Am J Hum Genet. 2003 Oct; 73(4): 898–925. Published online 2003 Sep 23. doi: 10.1086/378816

PMCID:: PMC1180611

Abstract Article PDF–1.6M

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