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Select item 92846601.

Silencing of Nesprin‐2 inhibits the differentiation of myofibroblasts from fibroblasts induced by mechanical stretch

Quanchen Xu, Yuanxin Miao, Jizheng Ren, Yu Sun, Cong Li, Xia Cai, Zhiguo Wang

Int Wound J. 2022 Aug; 19(5): 978–986. Published online 2021 Sep 23. doi: 10.1111/iwj.13694

PMCID:: PMC9284660

Abstract Article PDF–2.8M

Select item 38596922.

Nonsteroidal anti-inflammatory drug sulindac sulfide suppresses structural protein Nesprin-2 expression in colorectal cancer cells

Jason L. Liggett, Chang K. Choi, Robert L. Donnell, Kenneth D. Kihm, Jong-Sik Kim, Kyung-Won Min, Angelika Anna Noegel, Seung Joon Baek

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Jan; 1840(1): 10.1016/j.bbagen.2013.09.032. Published online 2013 Sep 27. doi: 10.1016/j.bbagen.2013.09.032

PMCID:: PMC3859692

Abstract Article PDF–1.8M

Select item 11654223.

Lamin A/C–dependent Localization of Nesprin-2, a Giant Scaffolder at the Nuclear Envelope

Thorsten Libotte, Hafida Zaim, Sabu Abraham, V. C. Padmakumar, Maria Schneider, Wenshu Lu, Martina Munck, Christopher Hutchison, Manfred Wehnert, Birthe Fahrenkrog, Ursula Sauder, Ueli Aebi, Angelika A. Noegel, Iakowos Karakesisoglou

Mol Biol Cell. 2005 Jul; 16(7): 3411–3424. doi: 10.1091/mbc.E04-11-1009

PMCID:: PMC1165422

Abstract Article PDF–1.0M

Select item 100365444.

Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression

Frederic Li Mow Chee, Bruno Beernaert, Billie G. C. Griffith, Alexander E. P. Loftus, Yatendra Kumar, Jimi C. Wills, Martin Lee, Jessica Valli, Ann P. Wheeler, J. Douglas Armstrong, Maddy Parsons, Irene M. Leigh, Charlotte M. Proby, Alex von Kriegsheim, Wendy A. Bickmore, Margaret C. Frame, Adam Byron

Nat Commun. 2023; 14: 1602. Published online 2023 Mar 23. doi: 10.1038/s41467-023-37021-x

PMCID:: PMC10036544

Abstract Article PDF–11M

Select item 67751145.

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle

Ian Holt, Heidi R. Fuller, Le Thanh Lam, Caroline A. Sewry, Sally L. Shirran, Qiuping Zhang, Catherine M. Shanahan, Glenn E. Morris

Sci Rep. 2019; 9: 14202. Published online 2019 Oct 2. doi: 10.1038/s41598-019-50728-6

PMCID:: PMC6775114

Abstract Article PDF–4.0M

Select item 49486826.

N-terminal nesprin-2 variants regulate β-catenin signalling

Qiuping Zhang, Rose-Marie Minaisah, Elisa Ferraro, Chen Li, Lauren J. Porter, Can Zhou, Fang Gao, Junyi Zhang, Dipen Rajgor, Flavia Autore, Catherine M. Shanahan, Derek T. Warren

Exp Cell Res. 2016 Jul 15; 345(2): 168–179. doi: 10.1016/j.yexcr.2016.06.008

PMCID:: PMC4948682

Abstract Article PDF–3.6M

Select item 39817897.

Nesprins: Tissue-Specific Expression of Epsilon and Other Short Isoforms

Nguyen Thuy Duong, Glenn E. Morris, Le Thanh Lam, Qiuping Zhang, Caroline A. Sewry, Catherine M. Shanahan, Ian Holt

PLoS One. 2014; 9(4): e94380. Published online 2014 Apr 9. doi: 10.1371/journal.pone.0094380

PMCID:: PMC3981789

Abstract Article PDF–7.5M

Select item 37480588.

Mutations in LMNA Modulate the Lamin A - Nesprin-2 Interaction and Cause LINC Complex Alterations

Liu Yang, Martina Munck, Karthic Swaminathan, Larisa E. Kapinos, Angelika A. Noegel, Sascha Neumann

PLoS One. 2013; 8(8): e71850. Published online 2013 Aug 20. doi: 10.1371/journal.pone.0071850

PMCID:: PMC3748058

Abstract Article PDF–7.0M

Select item 33880479.

Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds

Dipen Rajgor, Jason A. Mellad, Flavia Autore, Qiuping Zhang, Catherine M. Shanahan

PLoS One. 2012; 7(7): e40098. Published online 2012 Jul 2. doi: 10.1371/journal.pone.0040098

PMCID:: PMC3388047

Abstract Article PDF–1.8M

Select item 296610710.

Nesprin-2 Interacts with α-Catenin and Regulates Wnt Signaling at the Nuclear Envelope

Sascha Neumann, Maria Schneider, Rebecca L. Daugherty, Cara J. Gottardi, Sabine A. Eming, Asa Beijer, Angelika A. Noegel, Iakowos Karakesisoglou

J Biol Chem. 2010 Nov 5; 285(45): 34932–34938. Published online 2010 Aug 26. doi: 10.1074/jbc.M110.119651

PMCID:: PMC2966107

Abstract Article PDF–2.6M

Select item 1002279711.

Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders

Julie Yi, Xiaoxin Zhao, Crystal R. Noell, Paige Helmer, Sozanne R. Solmaz, Richard B. Vallee

PLoS Genet. 2023 Mar; 19(3): e1010642. Published online 2023 Mar 17. doi: 10.1371/journal.pgen.1010642

PMCID:: PMC10022797

Abstract Article PDF–3.4M

Select item 912209012.

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins

Sing Mei Lim, Victor E. Cruz, Susumu Antoku, Gregg G. Gundersen, Thomas U. Schwartz

Structure. Author manuscript; available in PMC 2022 Jun 3.

Published in final edited form as: Structure. 2021 Jun 3; 29(6): 540–552.e5. Published online 2021 Jan 19. doi: 10.1016/j.str.2020.12.013

PMCID:: PMC9122090

Abstract Article PDF–2.9M

Select item 865781313.

The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair

Samuel S. Wallis, Leandro N. Ventimiglia, Evita Otigbah, Elvira Infante, Miguel Angel Cuesta-Geijo, Gururaj Rao Kidiyoor, M. Alejandra Carbajal, Roland A. Fleck, Marco Foiani, Sergi Garcia-Manyes, Juan Martin-Serrano, Monica Agromayor

Dev Cell. 2021 Dec 6; 56(23): 3192–3202.e8. doi: 10.1016/j.devcel.2021.10.022

PMCID:: PMC8657813

Abstract Article

Select item 601508214.

LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration

Elvira Infante, Alessia Castagnino, Robin Ferrari, Pedro Monteiro, Sonia Agüera-González, Perrine Paul-Gilloteaux, Mélanie J. Domingues, Paolo Maiuri, Matthew Raab, Catherine M. Shanahan, Alexandre Baffet, Matthieu Piel, Edgar R. Gomes, Philippe Chavrier

Nat Commun. 2018; 9: 2443. Published online 2018 Jun 22. doi: 10.1038/s41467-018-04865-7

PMCID:: PMC6015082

Abstract Article PDF–4.4M

Select item 497750815.

EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma

Chuangye Han, Xiwen Liao, Wei Qin, Long Yu, Xiaoguang Liu, Gang Chen, Zhengtao Liu, Sicong Lu, Zhiwei Chen, Hao Su, Guangzhi Zhu, Zili Lu, Zhiming Liu, Xue Qin, Ying Gui, Zengnan Mo, Lequn Li, Tao Peng

Sci Rep. 2016; 6: 31237. Published online 2016 Aug 9. doi: 10.1038/srep31237

PMCID:: PMC4977508

Abstract Article PDF–2.1M

Select item 453277716.

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing

D T Warren, T Tajsic, L J Porter, R M Minaisah, A Cobb, A Jacob, D Rajgor, Q P Zhang, C M Shanahan

Cell Death Differ. 2015 Sep; 22(9): 1540–1550. Published online 2015 Mar 6. doi: 10.1038/cdd.2015.12

PMCID:: PMC4532777

Abstract Article PDF–2.9M

Select item 377875217.

LINC complex alterations in DMD and EDMD/CMT fibroblasts

Surayya Taranum, Eva Vaylann, Peter Meinke, Sabu Abraham, Liu Yang, Sascha Neumann, Iakowos Karakesisoglou, Manfred Wehnert, Angelika A. Noegel

Eur J Cell Biol. 2012 Aug; 91(8): 614–628. doi: 10.1016/j.ejcb.2012.03.003

PMCID:: PMC3778752

Abstract Article PDF–3.1M

Select item 280125818.

Novel Nuclear Nesprin-2 Variants Tether Active Extracellular Signal-regulated MAPK1 and MAPK2 at Promyelocytic Leukemia Protein Nuclear Bodies and Act to Regulate Smooth Muscle Cell Proliferation

Derek T. Warren, Tamara Tajsic, Jason A. Mellad, Richelle Searles, Qiuping Zhang, Catherine M. Shanahan

J Biol Chem. 2010 Jan 8; 285(2): 1311–1320. Published online 2009 Oct 27. doi: 10.1074/jbc.M109.032557

PMCID:: PMC2801258

Abstract Article PDF–2.4M

Select item 794047019.

The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal

Miki Hieda, Taizo Matsumoto, Mari Isobe, Sadamu Kurono, Kaneko Yuka, Satoshi Kametaka, Jing-Ya Wang, Ya-Hui Chi, Kenji Kameda, Hiroshi Kimura, Nariaki Matsuura, Shuji Matsuura

Sci Rep. 2021; 11: 5358. Published online 2021 Mar 8. doi: 10.1038/s41598-021-84750-4