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Items: 1 to 20 of 31

1.
LncRNA MCF2L-AS1 aggravates the malignant development of colorectal cancer via targeting miR-105-5p/RAB22A axis
Wencheng Kong, Hui Li, Lesi Xie, Guangxing Cui, Weigang Gu, Hongchen Zhang, Wencong Ma, Yifeng Zhou
BMC Cancer. 2021; 21: 1069. Published online 2021 Sep 30. doi: 10.1186/s12885-021-08668-w
PMCID:
PMC8482615
AbstractArticlePDF–3.1M
2.
Establishment of a human primary pancreatic cancer mouse model to examine and investigate gemcitabine resistance
Ya-Jing Zhang, Chen-Lei Wen, Yu-Xin Qin, Xiao-Mei Tang, Min-Min Shi, Bai-Yong Shen, Yuan Fang
Oncol Rep. 2017 Dec; 38(6): 3335–3346. Published online 2017 Oct 12. doi: 10.3892/or.2017.6026
PMCID:
PMC5783578
AbstractArticlePDF–1.0M
3.
A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis
Stephanie Maiwald, Mahdi M Motazacker, Julian C van Capelleveen, Suthesh Sivapalaratnam, Allard C van der Wal, Chris van der Loos, John J P Kastelein, Willem H Ouwehand, G Kees Hovingh, Mieke D Trip, Jaap D van Buul, Geesje M Dallinga-Thie
Eur J Hum Genet. 2016 Jan; 24(1): 86–91. Published online 2015 Apr 22. doi: 10.1038/ejhg.2015.70
PMCID:
PMC4795224
AbstractArticlePDF–1.4M
4.
Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874
Colin Shepherd, Andrew J. Skelton, Michael D. Rushton, Louise N. Reynard, John Loughlin
BMC Med Genet. 2015; 16: 108. Published online 2015 Nov 19. doi: 10.1186/s12881-015-0254-2
PMCID:
PMC4653905
AbstractArticlePDF–760K
5.
Regulation of vesicle transport and cell motility by Golgi-localized Dbs
Ethan R Fitzpatrick, Tinghui Hu, Bryan T Ciccarelli, Ian P Whitehead
Small GTPases. 2014; 5(4): e972860. Published online 2014 Oct 31. doi: 10.4161/sgtp.28570
PMCID:
PMC4601361
AbstractArticlePDF–992K
6.
A Variant in MCF2L Is Associated with Osteoarthritis
Aaron G. Day-Williams, Lorraine Southam, Kalliope Panoutsopoulou, Nigel W. Rayner, Tonu Esko, Karol Estrada, Hafdis T. Helgadottir, Albert Hofman, Throvaldur Ingvarsson, Helgi Jonsson, Aime Keis, Hanneke J.M. Kerkhof, Gudmar Thorleifsson, Nigel K. Arden, Andrew Carr, Kay Chapman, Panos Deloukas, John Loughlin, Andrew McCaskie, William E.R. Ollier, Stuart H. Ralston, Timothy D. Spector, Gillian A. Wallis, J. Mark Wilkinson, Nadim Aslam, Fraser Birell, Ian Carluke, John Joseph, Ashok Rai, Mike Reed, Kirsten Walker, arcOGEN Consortium, Sally A. Doherty, Ingileif Jonsdottir, Rose A. Maciewicz, Kenneth R. Muir, Andres Metspalu, Fernando Rivadeneira, Kari Stefansson, Unnur Styrkarsdottir, Andre G. Uitterlinden, Joyce B.J. van Meurs, Weiya Zhang, Ana M. Valdes, Michael Doherty, Eleftheria Zeggini
Am J Hum Genet. 2011 Sep 9; 89(3): 446–450. doi: 10.1016/j.ajhg.2011.08.001
PMCID:
PMC3169824
AbstractArticlePDF–444K
7.
The Rho-specific Guanine Nucleotide Exchange Factor Dbs Regulates Breast Cancer Cell Migration
Zhuoming Liu, Homer C. Adams, III, Ian P. Whitehead
J Biol Chem. 2009 Jun 5; 284(23): 15771–15780. Published online 2009 Apr 14. doi: 10.1074/jbc.M901853200
PMCID:
PMC2708874
AbstractArticlePDF–1.2M
8.
RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming Activity
Li Cheng, Kent L. Rossman, Gwendolyn M. Mahon, David K. Worthylake, Malgorzata Korus, John Sondek, Ian P. Whitehead
Mol Cell Biol. 2002 Oct; 22(19): 6895–6905. doi: 10.1128/MCB.22.19.6895-6905.2002
PMCID:
PMC134030
AbstractArticlePDF–529K
9.
Dependence of Dbl and Dbs Transformation on MEK and NF-κB Activation
Ian P. Whitehead, Que T. Lambert, Judith A. Glaven, Karon Abe, Kent L. Rossman, Gwendolyn M. Mahon, James M. Trzaskos, Robert Kay, Sharon L. Campbell, Channing J. Der
Mol Cell Biol. 1999 Nov; 19(11): 7759–7770. doi: 10.1128/mcb.19.11.7759
PMCID:
PMC84831
AbstractArticlePDF–1.1M
10.
Genetic contribution to radiographic severity in osteoarthritis of the knee
Ana M Valdes, Sally Doherty, Kenneth R Muir, Weiya Zhang, Rose A Maciewicz, Margaret Wheeler, Nigel Arden, Cyrus Cooper, M Doherty
Ann Rheum Dis. 2012 Sep; 71(9): 1537–1540. doi: 10.1136/annrheumdis-2012-201382
PMCID:
PMC3414227
AbstractArticlePDF–267K
11.
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways.
Y Horii, J F Beeler, K Sakaguchi, M Tachibana, T Miki
EMBO J. 1994 Oct 17; 13(20): 4776–4786. doi: 10.1002/j.1460-2075.1994.tb06803.x
PMCID:
PMC395416
SummaryPage BrowsePDF–2.9M
12.
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange
Kent L. Rossman, David K. Worthylake, Jason T. Snyder, David P. Siderovski, Sharon L. Campbell, John Sondek
EMBO J. 2002 Mar 15; 21(6): 1315–1326. doi: 10.1093/emboj/21.6.1315
PMCID:
PMC125919
AbstractArticlePDF–646K
13.
Ccpg1, a Novel Scaffold Protein That Regulates the Activity of the Rho Guanine Nucleotide Exchange Factor Dbs
Elena V. Kostenko, Oyenike O. Olabisi, Sutapa Sahay, Pedro L. Rodriguez, Ian P. Whitehead
Mol Cell Biol. 2006 Dec; 26(23): 8964–8975. Published online 2006 Sep 25. doi: 10.1128/MCB.00670-06
PMCID:
PMC1636807
AbstractArticlePDF–1002K
14.
Ischemic Stroke Is Associated with the ABO Locus: The EuroCLOT Study
Frances M K Williams, Angela M Carter, Pirro G Hysi, Gabriela Surdulescu, Dylan Hodgkiss, Nicole Soranzo, Matthew Traylor, Steve Bevan, Martin Dichgans, Peter M W Rothwell, Cathie Sudlow, Martin Farrall, Kaisa Silander, Mari Kaunisto, Peter Wagner, Olli Saarela, Kari Kuulasmaa, Jarmo Virtamo, Veikko Salomaa, Philippe Amouyel, Dominique Arveiler, Jean Ferrieres, Per-Gunnar Wiklund, M Arfan Ikram, Albert Hofman, Giorgio B Boncoraglio, Eugenio A Parati, Anna Helgadottir, Solveig Gretarsdottir, Unnur Thorsteinsdottir, Gudmar Thorleifsson, Kari Stefansson, Sudha Seshadri, Anita DeStefano, Andreas Gschwendtner, Bruce Psaty, Will Longstreth, Braxton D Mitchell, Yu-Ching Cheng, Robert Clarke, Marco Ferrario, Joshua C Bis, Christopher Levi, John Attia, Elizabeth G Holliday, Rodney J Scott, Myriam Fornage, Pankaj Sharma, Karen L Furie, Jonathan Rosand, Mike Nalls, James Meschia, Thomas H Mosely, Alun Evans, Aarno Palotie, Hugh S Markus, Peter J Grant, Tim D Spector, on Behalf of the EuroCLOT Investigators, the Wellcome Trust Case Control Consortium 2, MOnica Risk, Genetics, Archiving and Monograph, MetaStroke, and the International Stroke Genetics Consortium
Ann Neurol. 2013 Jan; 73(1): 16–31. Published online 2013 Feb 4. doi: 10.1002/ana.23838
PMCID:
PMC3582024
AbstractArticlePDF–577K
15.
Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study
Qiong Yang, Sekar Kathiresan, Jing-Ping Lin, Geoffrey H Tofler, Christopher J O'Donnell
BMC Med Genet. 2007; 8(Suppl 1): S12. Published online 2007 Sep 19. doi: 10.1186/1471-2350-8-S1-S12
PMCID:
PMC1995619
AbstractArticlePDF–309K
16.
Genome-wide association study identifies multiple loci associated with bladder cancer risk
Jonine D. Figueroa, Yuanqing Ye, Afshan Siddiq, Montserrat Garcia-Closas, Nilanjan Chatterjee, Ludmila Prokunina-Olsson, Victoria K. Cortessis, Charles Kooperberg, Olivier Cussenot, Simone Benhamou, Jennifer Prescott, Stefano Porru, Colin P. Dinney, Núria Malats, Dalsu Baris, Mark Purdue, Eric J. Jacobs, Demetrius Albanes, Zhaoming Wang, Xiang Deng, Charles C. Chung, Wei Tang, H. Bas Bueno-de-Mesquita, Dimitrios Trichopoulos, Börje Ljungberg, Françoise Clavel-Chapelon, Elisabete Weiderpass, Vittorio Krogh, Miren Dorronsoro, Ruth Travis, Anne Tjønneland, Paul Brenan, Jenny Chang-Claude, Elio Riboli, David Conti, Manuela Gago-Dominguez, Mariana C. Stern, Malcolm C. Pike, David Van Den Berg, Jian-Min Yuan, Chancellor Hohensee, Rebecca Rodabough, Geraldine Cancel-Tassin, Morgan Roupret, Eva Comperat, Constance Chen, Immaculata De Vivo, Edward Giovannucci, David J. Hunter, Peter Kraft, Sara Lindstrom, Angela Carta, Sofia Pavanello, Cecilia Arici, Giuseppe Mastrangelo, Ashish M. Kamat, Seth P. Lerner, H. Barton Grossman, Jie Lin, Jian Gu, Xia Pu, Amy Hutchinson, Laurie Burdette, William Wheeler, Manolis Kogevinas, Adonina Tardón, Consol Serra, Alfredo Carrato, Reina García-Closas, Josep Lloreta, Molly Schwenn, Margaret R. Karagas, Alison Johnson, Alan Schned, Karla R. Armenti, G.M. Hosain, Gerald Andriole, Jr, Robert Grubb, III, Amanda Black, W. Ryan Diver, Susan M. Gapstur, Stephanie J. Weinstein, Jarmo Virtamo, Chris A. Haiman, Maria T. Landi, Neil Caporaso, Joseph F. Fraumeni, Jr, Paolo Vineis, Xifeng Wu, Debra T. Silverman, Stephen Chanock, Nathaniel Rothman
Hum Mol Genet. 2014 Mar 1; 23(5): 1387–1398. Published online 2013 Oct 24. doi: 10.1093/hmg/ddt519
PMCID:
PMC3919005
AbstractArticlePDF–580K
17.
Activation of Rac GTPase by p75 Is Necessary for c-jun N-Terminal Kinase-Mediated Apoptosis
Anthony W. Harrington, Ju Young Kim, Sung Ok Yoon
J Neurosci. 2002 Jan 1; 22(1): 156–166. doi: 10.1523/JNEUROSCI.22-01-00156.2002
PMCID:
PMC6757583
AbstractArticlePDF–582K
18.
Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer‐related pathways in breast cancer
Yan Liu, Jian Li, Zhifang Ma, Jun Zhang, Yuzhi Wang, Zhenghong Yu, Xue Lin, Zhi Xu, Qian Su, Li An, Yehui Zhou, Xinxing Ma, Yiwen Yang, Feifei Wang, Qingfei Chen, Yunchao Zhang, Jilinlin Wang, Huilin Zheng, Aihua Shi, Shuang Yu, Jingzhong Zhang, Weiyong Zhao, Liming Chen
Cancer Med. 2019 Feb; 8(2): 729–741. Published online 2019 Jan 16. doi: 10.1002/cam4.1938
PMCID:
PMC6504119
AbstractArticlePDF–1.3M
19.
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach
DANIEL BÖHM, KSENIA KELLER, JULIA PIETER, NILS BOEHM, DOMINIK WOLTERS, WULF SIGGELKOW, ANTJE LEBRECHT, MARCUS SCHMIDT, HEINZ KÖLBL, NORBERT PFEIFFER, FRANZ-HERMANN GRUS
Oncol Rep. 2012 Aug; 28(2): 429–438. Published online 2012 Jun 1. doi: 10.3892/or.2012.1849
PMCID:
PMC3583517
AbstractArticlePDF–501K
20.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116
Correction in:
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.
PMCID:
PMC6600915
AbstractArticlePDF–1.7M

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