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Items: 1 to 20 of 57

1.
The E3 ligase UBR2 regulates cell death under caspase deficiency via Erk/MAPK pathway
Elodie Villa, Rachel Paul, Ophélie Meynet, Sophie Volturo, Guillaume Pinna, Jean-Ehrland Ricci
Cell Death Dis. 2020 Dec; 11(12): 1041. Published online 2020 Dec 8. doi: 10.1038/s41419-020-03258-3
PMCID:
PMC7721896
AbstractArticlePDF–1.9M
2.
Single nucleotide polymorphism in the UBR2 gene may be a genetic risk factor for Japanese patients with azoospermia by meiotic arrest
Toshinobu Miyamoto, Akira Tsujimura, Yasushi Miyagawa, Eitetsu Koh, Mikio Namiki, Michiharu Horikawa, Yasuaki Saijo, Kazuo Sengoku
J Assist Reprod Genet. 2011 Aug; 28(8): 743–746. Published online 2011 May 4. doi: 10.1007/s10815-011-9576-y
PMCID:
PMC3170112
AbstractArticlePDF–97K
3.
The N‐end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin
Hao Xu, Jianjin Shi, Hang Gao, Ying Liu, Zhenxiao Yang, Feng Shao, Na Dong
EMBO J. 2019 Jul 1; 38(13): e101996. Published online 2019 May 6. doi: 10.15252/embj.2019101996
PMCID:
PMC6600268
AbstractArticlePDF–1.8M
4.
UBR2 of the N-End Rule Pathway Is Required for Chromosome Stability via Histone Ubiquitylation in Spermatocytes and Somatic Cells
Jee Young An, Euna Kim, Adriana Zakrzewska, Young Dong Yoo, Jun Min Jang, Dong Hoon Han, Min Jae Lee, Jai Wha Seo, Yong Jun Lee, Tae-You Kim, Dirk G. de Rooij, Bo Yeon Kim, Yong Tae Kwon
PLoS One. 2012; 7(5): e37414. Published online 2012 May 17. doi: 10.1371/journal.pone.0037414
PMCID:
PMC3355131
AbstractArticlePDF–1.5M
5.
The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling
Ying-Chun Shih, Hsueh-Fen Chen, Chia-Ying Wu, Yi-Ru Ciou, Chia-Wen Wang, Huai-Chia Chuang, Tse-Hua Tan
Nat Commun. 2024; 15: 532. Published online 2024 Jan 15. doi: 10.1038/s41467-024-44843-w
PMCID:
PMC10789758
AbstractArticlePDF–5.3M
6.
The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway
Tri T. M. Vu, Alexander Varshavsky
Biochemistry. Author manuscript; available in PMC 2020 Nov 17.
Published in final edited form as: Biochemistry. 2020 Aug 4; 59(30): 2796–2812. Published online 2020 Jul 21. doi: 10.1021/acs.biochem.0c00514
PMCID:
PMC7669821
AbstractArticlePDF–1.9M
7.
Identification of Ubr1 as an amino acid sensor of steatosis in liver and muscle
Wanni Zhao, Yansong Zhang, Siyuan Lin, Yajuan Li, Alan Jian Zhu, Hanping Shi, Min Liu
J Cachexia Sarcopenia Muscle. 2023 Jun; 14(3): 1454–1467. Published online 2023 Apr 13. doi: 10.1002/jcsm.13233
PMCID:
PMC10235883
AbstractArticlePDF–8.9M
8.
Alternative Ubiquitin Activation/Conjugation Cascades Interact with N-end rule Ubiquitin Ligases to Control Degradation of RGS Proteins
Peter C.W. Lee, Mathew E. Sowa, Steven P. Gygi, J. Wade Harper
Mol Cell. Author manuscript; available in PMC 2012 Aug 5.
Published in final edited form as: Mol Cell. 2011 Aug 5; 43(3): 392–405. doi: 10.1016/j.molcel.2011.05.034
PMCID:
PMC3151487
AbstractArticlePDF–2.6M
9.
Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway
Yong Tae Kwon, Zanxian Xia, Jee Young An, Takafumi Tasaki, Ilia V. Davydov, Jai Wha Seo, Jun Sheng, Youming Xie, Alexander Varshavsky
Mol Cell Biol. 2003 Nov; 23(22): 8255–8271. doi: 10.1128/MCB.23.22.8255-8271.2003
PMCID:
PMC262401
AbstractArticlePDF–1.8M
10.
Human Immunodeficiency Virus Type 1 Vpr Links Proteasomal Degradation and Checkpoint Activation
Jason L. DeHart, Vicente Planelles
J Virol. 2008 Feb; 82(3): 1066–1072. Published online 2007 Sep 12. doi: 10.1128/JVI.01628-07
PMCID:
PMC2224437
ArticlePDF–222K
11.
UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination
Jee Young An, Eun-A. Kim, Yonghua Jiang, Adriana Zakrzewska, Dong Eun Kim, Min Jae Lee, Inhee Mook-Jung, Yi Zhang, Yong Tae Kwon
Proc Natl Acad Sci U S A. 2010 Feb 2; 107(5): 1912–1917. Published online 2010 Jan 11. doi: 10.1073/pnas.0910267107
PMCID:
PMC2836623
AbstractArticlePDF–1.4M
12.
Five enzymes of the Arg/N-degron pathway form a targeting complex: The concept of superchanneling
Jang-Hyun Oh, Ju-Yeon Hyun, Shun-Jia Chen, Alexander Varshavsky
Proc Natl Acad Sci U S A. 2020 May 19; 117(20): 10778–10788. Published online 2020 May 4. doi: 10.1073/pnas.2003043117
PMCID:
PMC7245096
AbstractArticlePDF–1.7M
13.
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1
Bärbel Schröfelbauer, Yoshiyuki Hakata, Nathaniel R. Landau
Proc Natl Acad Sci U S A. 2007 Mar 6; 104(10): 4130–4135. Published online 2007 Feb 28. doi: 10.1073/pnas.0610167104
PMCID:
PMC1820720
AbstractArticlePDF–500K
14.
Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6
Monica C. Rodrigo-Brenni, Erik Gutierrez, Ramanujan S. Hegde
Mol Cell. 2014 Jul 17; 55(2): 227–237. doi: 10.1016/j.molcel.2014.05.025
PMCID:
PMC4104027
AbstractArticle
15.
Vif hijacks CBF – β to degrade APOBEC3G and promote HIV–1 infection
Stefanie Jäger, Dong Young Kim, Judd F. Hultquist, Keisuke Shindo, Rebecca S. LaRue, Eunju Kwon, Ming Li, Brett D. Anderson, Linda Yen, David Stanley, Cathal Mahon, Joshua Kane, Kathy Franks-Skiba, Peter Cimermancic, Alma Burlingame, Andrej Sali, Charles S. Craik, Reuben S. Harris, John D. Gross, Nevan J. Krogan
Nature. Author manuscript; available in PMC 2013 Jan 19.
Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 371–375. Published online 2011 Dec 21. doi: 10.1038/nature10693
PMCID:
PMC3310910
AbstractArticlePDF–928K
16.
KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and Lysosome-Mediated Degradation
Jenny H. Hong, Lilia Kaustov, Etienne Coyaud, Tharan Srikumar, Janet Wan, Cheryl Arrowsmith, Brian Raught
Mol Cell Proteomics. 2015 Mar; 14(3): 674–685. Published online 2015 Jan 12. doi: 10.1074/mcp.M114.042168
PMCID:
PMC4349986
AbstractArticlePDF–3.4M
17.
Genome-wide association study of smoking behaviors among Bangladeshi adults
Maria Argos, Lin Tong, Brandon L. Pierce, Muhammad Rakibuz-Zaman, Alauddin Ahmed, Tariqul Islam, Mahfuzar Rahman, Rachelle Paul-Brutus, Ronald Rahaman, Shantanu Roy, Farzana Jasmine, Muhammad G. Kibriya, Habibul Ahsan
J Med Genet. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: J Med Genet. 2014 May; 51(5): 327–333. Published online 2014 Mar 24. doi: 10.1136/jmedgenet-2013-102151
PMCID:
PMC4126189
AbstractArticlePDF–672K
18.
14-3-3ε Mediates the Cell Fate Decision-Making Pathways in Response of Hepatocellular Carcinoma to Bleomycin-Induced DNA Damage
Siwei Tang, Huimin Bao, Yang Zhang, Jun Yao, Pengyuan Yang, Xian Chen
PLoS One. 2013; 8(3): e55268. Published online 2013 Mar 5. doi: 10.1371/journal.pone.0055268
PMCID:
PMC3589417
AbstractArticlePDF–2.8M
19.
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover
Gabriela Alexandru, Johannes Graumann, Geoffrey T. Smith, Natalie J. Kolawa, Ruihua Fang, Raymond J. Deshaies
Cell. Author manuscript; available in PMC 2009 Mar 5.
Published in final edited form as: Cell. 2008 Sep 5; 134(5): 804–816. doi: 10.1016/j.cell.2008.06.048
PMCID:
PMC2614663
AbstractArticlePDF–3.7M
20.
Ubiquitin Ligase Substrate Identification through Quantitative Proteomics at Both the Protein and Peptide Levels
Kimberly A. Lee, Lisa P. Hammerle, Paul S. Andrews, Matthew P. Stokes, Tomas Mustelin, Jeffrey C. Silva, Roy A. Black, John R. Doedens
J Biol Chem. 2011 Dec 2; 286(48): 41530–41538. Published online 2011 Oct 10. doi: 10.1074/jbc.M111.248856
PMCID:
PMC3308864
AbstractArticlePDF–815K

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