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Select item 90902971.

CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner

Haytham Mohamed Aly Mohamed, Akinori Takahashi, Saori Nishijima, Shungo Adachi, Iori Murai, Hitoshi Okamura, Tadashi Yamamoto

RNA Biol. 2022; 19(1): 703–718. Published online 2022 May 5. doi: 10.1080/15476286.2022.2071026

PMCID:: PMC9090297

Abstract Article PDF–3.4M

Select item 68622162.

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

Akinori Takahashi, Shohei Takaoka, Shungo Kobori, Tomokazu Yamaguchi, Sara Ferwati, Keiji Kuba, Tadashi Yamamoto, Toru Suzuki

Int J Mol Sci. 2019 Nov; 20(21): 5274. Published online 2019 Oct 24. doi: 10.3390/ijms20215274

PMCID:: PMC6862216

Abstract Article PDF–7.5M

Select item 113010683.

Decline in corepressor CNOT1 in the pregnant myometrium near term impairs progesterone receptor function and increases contractile gene expression

Youn-Tae Kwak, Alina P. Montalbano, Andrew M. Kelleher, Mariano Colon-Caraballo, W. Lee Kraus, Mala Mahendroo, Carole R. Mendelson

J Biol Chem. 2024 Jul; 300(7): 107484. Published online 2024 Jun 18. doi: 10.1016/j.jbc.2024.107484

PMCID:: PMC11301068

Abstract Article PDF–1.4M

Select item 71193704.

The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

Akinori Takahashi, Toru Suzuki, Shou Soeda, Shohei Takaoka, Shungo Kobori, Tomokazu Yamaguchi, Haytham Mohamed Aly Mohamed, Akiko Yanagiya, Takaya Abe, Mayo Shigeta, Yasuhide Furuta, Keiji Kuba, Tadashi Yamamoto

Life Sci Alliance. 2020 May; 3(5): e201900494. Published online 2020 Apr 1. doi: 10.26508/lsa.201900494

PMCID:: PMC7119370

Abstract Article PDF–6.4M

Select item 65068675.

A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly

Paul Kruszka, Seth I. Berger, Karin Weiss, Joshua L. Everson, Ariel F. Martinez, Sungkook Hong, Kwame Anyane-Yeboa, Robert J. Lipinski, Maximilian Muenke

Am J Hum Genet. 2019 May 2; 104(5): 990–993. Published online 2019 Apr 18. doi: 10.1016/j.ajhg.2019.03.017

PMCID:: PMC6506867

Abstract Article PDF–606K

Select item 47264976.

Post-transcriptional Control of Tumor Cell Autonomous Metastatic Potential by CCR4-NOT Deadenylase CNOT7

Farhoud Faraji, Ying Hu, Howard H. Yang, Maxwell P. Lee, G. Sebastian Winkler, Markus Hafner, Kent W. Hunter

PLoS Genet. 2016 Jan; 12(1): e1005820. Published online 2016 Jan 25. doi: 10.1371/journal.pgen.1005820

PMCID:: PMC4726497

Abstract Article PDF–3.7M

Select item 41554197.

Identification of Ccr4-Not Complex Components as Regulators of Transition from Partial to Genuine Induced Pluripotent Stem Cells

Masayoshi Kamon, Miyuki Katano, Keiko Hiraki-Kamon, Tomoaki Hishida, Yutaka Nakachi, Yosuke Mizuno, Yasushi Okazaki, Ayumu Suzuki, Masataka Hirasaki, Atsushi Ueda, Masazumi Nishimoto, Hidemasa Kato, Akihiko Okuda

Stem Cells Dev. 2014 Sep 15; 23(18): 2170–2179. Published online 2013 Nov 8. doi: 10.1089/scd.2013.0326

PMCID:: PMC4155419

Abstract Article PDF–691K

Select item 69996318.

Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability

Dina Mostafa, Akinori Takahashi, Akiko Yanagiya, Tomokazu Yamaguchi, Takaya Abe, Taku Kureha, Keiji Kuba, Yumi Kanegae, Yasuhide Furuta, Tadashi Yamamoto, Toru Suzuki

RNA Biol. 2020; 17(3): 403–416. Published online 2020 Jan 10. doi: 10.1080/15476286.2019.1709747

PMCID:: PMC6999631

Abstract Article PDF–6.3M

Select item 37877179.

Cnot1, Cnot2, and Cnot3 Maintain Mouse and Human ESC Identity and Inhibit Extraembryonic Differentiation

Xiaofeng Zheng, Raluca Dumitru, Brad L. Lackford, Johannes M. Freudenberg, Ajeet P. Singh, Trevor K. Archer, Raja Jothi, Guang Hu

Stem Cells. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: Stem Cells. 2012 May; 30(5): 910–922. doi: 10.1002/stem.1070

PMCID:: PMC3787717

Abstract Article PDF–3.4M

Select item 650686210.

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development

Elisa De Franco, Rachel A. Watson, Wolfgang J. Weninger, Chi C. Wong, Sarah E. Flanagan, Richard Caswell, Angela Green, Catherine Tudor, Christopher J. Lelliott, Stefan H. Geyer, Barbara Maurer-Gesek, Lukas F. Reissig, Hana Lango Allen, Almuth Caliebe, Reiner Siebert, Paul Martin Holterhus, Asma Deeb, Fabrice Prin, Robert Hilbrands, Harry Heimberg, Sian Ellard, Andrew T. Hattersley, Inês Barroso

Am J Hum Genet. 2019 May 2; 104(5): 985–989. Published online 2019 Apr 18. doi: 10.1016/j.ajhg.2019.03.018

PMCID:: PMC6506862

Abstract Article PDF–1.2M

Select item 524230311.

mTOR regulates the expression of DNA damage response enzymes in long‐lived Snell dwarf, GHRKO, and PAPPA‐KO mice

Graham Dominick, Jacqueline Bowman, Xinna Li, Richard A. Miller, Gonzalo G. Garcia

Aging Cell. 2017 Feb; 16(1): 52–60. Published online 2016 Sep 13. doi: 10.1111/acel.12525

PMCID:: PMC5242303

Abstract Article PDF–895K

Select item 330899212.

Interaction between NANOS2 and the CCR4-NOT Deadenylation Complex Is Essential for Male Germ Cell Development in Mouse

Atsushi Suzuki, Rie Saba, Kei Miyoshi, Yoshinori Morita, Yumiko Saga

PLoS One. 2012; 7(3): e33558. Published online 2012 Mar 20. doi: 10.1371/journal.pone.0033558

PMCID:: PMC3308992

Abstract Article PDF–3.1M

Select item 471841413.

Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development

Atsushi Suzuki, Yuki Niimi, Kaori Shinmyozu, Zhi Zhou, Makoto Kiso, Yumiko Saga

EMBO Rep. 2016 Jan; 17(1): 37–46. Published online 2015 Nov 20. doi: 10.15252/embr.201540828

PMCID:: PMC4718414

Abstract Article PDF–2.0M

Select item 284049914.

NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs

Atsushi Suzuki, Katsuhide Igarashi, Ken-ichi Aisaki, Jun Kanno, Yumiko Saga

Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8): 3594–3599. Published online 2010 Feb 2. doi: 10.1073/pnas.0908664107

PMCID:: PMC2840499

Abstract Article PDF–1.2M

Select item 195148915.

Depletion of Mammalian CCR4b Deadenylase Triggers Elevation of the p27^Kip1 mRNA Level and Impairs Cell Growth

Masahiro Morita, Toru Suzuki, Takahisa Nakamura, Kazumasa Yokoyama, Takashi Miyasaka, Tadashi Yamamoto

Mol Cell Biol. 2007 Jul; 27(13): 4980–4990. Published online 2007 Apr 23. doi: 10.1128/MCB.02304-06

PMCID:: PMC1951489

Abstract Article PDF–1.1M

Select item 1114090716.

Knockout mice with pituitary malformations help identify human cases of hypopituitarism

Julian Martinez-Mayer, Michelle L. Brinkmeier, Sean P. O’Connell, Arnold Ukagwu, Marcelo A. Marti, Mirta Miras, Maria V. Forclaz, Maria G. Benzrihen, Leonard Y. M. Cheung, Sally A. Camper, Buffy S. Ellsworth, Lori T. Raetzman, Maria I. Pérez-Millán, Shannon W. Davis

Genome Med. 2024; 16: 75. Published online 2024 May 31. doi: 10.1186/s13073-024-01347-y

PMCID:: PMC11140907

Abstract Article PDF–4.4M

Select item 639844717.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Abstract Article

Select item 374619818.

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal

Alessia Gagliardi, Nicholas P Mullin, Zi Ying Tan, Douglas Colby, Anastasia I Kousa, Florian Halbritter, Jason T Weiss, Anastasia Felker, Karel Bezstarosti, Rebecca Favaro, Jeroen Demmers, Silvia K Nicolis, Simon R Tomlinson, Raymond A Poot, Ian Chambers

EMBO J. 2013 Aug 14; 32(16): 2231–2247. Published online 2013 Jul 26. doi: 10.1038/emboj.2013.161

PMCID:: PMC3746198

Abstract Article PDF–2.9M

Select item 373458119.

Phosphoinositide-specific Phospholipase C β 1b (PI-PLCβ1b) Interactome: Affinity Purification-Mass Spectrometry Analysis of PI-PLCβ1b with Nuclear Protein

Manuela Piazzi, William L. Blalock, Alberto Bavelloni, Irene Faenza, Antonietta D'Angelo, Nadir M. Maraldi, Lucio Cocco

Mol Cell Proteomics. 2013 Aug; 12(8): 2220–2235. Published online 2013 May 9. doi: 10.1074/mcp.M113.029686

PMCID:: PMC3734581

Abstract Article PDF–1.9M

Select item 325246520.

Oct4 links multiple epigenetic pathways to the pluripotency network

Junjun Ding, Huilei Xu, Francesco Faiola, Avi Ma'ayan, Jianlong Wang

Cell Res. 2012 Jan; 22(1): 155–167. Published online 2011 Nov 15. doi: 10.1038/cr.2011.179

PMCID:: PMC3252465

Abstract Article PDF–2.7M

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