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Select item 112016491.

Moderate SCRIB Expression Levels Correlate with Worse Prognosis in OPSCC Patients Regardless of HPV Status

Lucija Lulić, Ivana Šimić, Ksenija Božinović, Ena Pešut, Luka Manojlović, Magdalena Grce, Emil Dediol, Ivan Sabol, Vjekoslav Tomaić

Cells. 2024 Jun; 13(12): 1002. Published online 2024 Jun 8. doi: 10.3390/cells13121002

PMCID:: PMC11201649

Abstract Article PDF–1.6M

Select item 84488702.

Discovery of a small protein-encoding cis-regulatory overlapping gene of the tumor suppressor gene Scribble in humans

Yuhta Nomura, Naoshi Dohmae

Commun Biol. 2021; 4: 1098. Published online 2021 Sep 17. doi: 10.1038/s42003-021-02619-8

PMCID:: PMC8448870

Abstract Article PDF–2.8M

Select item 84175073.

An antisense circular RNA circSCRIB enhances cancer progression by suppressing parental gene splicing and translation

Jian Ma, William W. Du, Kaixuan Zeng, Nan Wu, Ling Fang, Juanjuan Lyu, Albert J. Yee, Burton B. Yang

Mol Ther. 2021 Sep 1; 29(9): 2754–2768. Published online 2021 Aug 6. doi: 10.1016/j.ymthe.2021.08.002

PMCID:: PMC8417507

Abstract Article PDF–3.7M

Select item 80002144.

SCRIB Is Involved in the Progression of Ovarian Carcinomas in Association with the Factors Linked to Epithelial-to-Mesenchymal Transition and Predicts Shorter Survival of Diagnosed Patients

Usama Khamis Hussein, Asmaa Gamal Ahmed, Won Ku Choi, Kyoung Min Kim, See-Hyoung Park, Ho Sung Park, Sang Jae Noh, Ho Lee, Myoung Ja Chung, Woo Sung Moon, Myoung Jae Kang, Dong Hyu Cho, Kyu Yun Jang

Biomolecules. 2021 Mar; 11(3): 405. Published online 2021 Mar 9. doi: 10.3390/biom11030405

PMCID:: PMC8000214

Abstract Article PDF–5.8M

Select item 67965315.

Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling

Na Wang, Lele Song, Yi Xu, Longfu Zhang, Yanjun Wu, Jingyu Guo, Weiwei Ji, Li Li, Jingya Zhao, Xin Zhang, Lixing Zhan

EBioMedicine. 2019 Sep; 47: 65–77. Published online 2019 Sep 5. doi: 10.1016/j.ebiom.2019.08.057

PMCID:: PMC6796531

Abstract Article PDF–4.2M

Select item 67736906.

Scribble co-operatively binds multiple α_1D-adrenergic receptor C-terminal PDZ ligands

Eric M. Janezic, Dorathy-Ann Harris, Diana Dinh, Kyung-Soon Lee, Aaron Stewart, Thomas R. Hinds, Peter L. Hsu, Ning Zheng, Chris Hague

Sci Rep. 2019; 9: 14073. Published online 2019 Oct 1. doi: 10.1038/s41598-019-50671-6

PMCID:: PMC6773690

Abstract Article PDF–3.5M

Select item 58868767.

The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines

Christian Kranjec, Vjekoslav Tomaić, Paola Massimi, Lietta Nicolaides, John Doorbar, Lawrence Banks

Papillomavirus Res. 2016 Dec; 2: 70–77. Published online 2016 Apr 7. doi: 10.1016/j.pvr.2016.04.001

PMCID:: PMC5886876

Abstract Article PDF–1.5M

Select item 54322768.

The cell polarity protein Scrib functions as a tumor suppressor in liver cancer

Shweta Kapil, Bal Krishan Sharma, Mallikarjun Patil, Sawsan Elattar, Jinling Yuan, Steven X. Hou, Ravindra Kolhe, Ande Satyanarayana

Oncotarget. 2017 Apr 18; 8(16): 26515–26531. Published online 2017 Feb 24. doi: 10.18632/oncotarget.15713

PMCID:: PMC5432276

Abstract Article PDF–8.6M

Select item 53621239.

APT2 inhibition restores Scribble localization and S-palmitoylation in Snail-transformed cells

Jeannie L. Hernandez, Dahvid Davda, Melanie Cheung See Kit, Jaimeen D. Majmudar, Sang Joon Won, Margery Gang, Sirisha C. Pasupuleti, Alexandria I. Choi, Callie M. Bartkowiak, Brent R. Martin

Cell Chem Biol. Author manuscript; available in PMC 2018 Jan 19.

Published in final edited form as: Cell Chem Biol. 2017 Jan 19; 24(1): 87–97. Published online 2017 Jan 5. doi: 10.1016/j.chembiol.2016.12.007

PMCID:: PMC5362123

Abstract Article PDF–1.6M

Select item 491950410.

Decreased Usage of Specific Scrib Exons Defines a More Malignant Phenotype of Breast Cancer With Worsened Survival

Gergana Metodieva, Samson Adoki, Berthold Lausen, Metodi V. Metodiev

EBioMedicine. 2016 Jun; 8: 150–158. Published online 2016 May 7. doi: 10.1016/j.ebiom.2016.05.009

PMCID:: PMC4919504

Abstract Article PDF–1.1M

Select item 409680811.

Mislocalization of the cell polarity protein Scribble promotes mammary tumorigenesis and is associated with basal breast cancer

Michael E. Feigin, S. Dipikaa Akshinthala, Kiyomi Araki, Avi Z. Rosenberg, Lakshmi B. Muthuswamy, Bernard Martin, Brian D. Lehmann, Hal K. Berman, Jennifer A. Pietenpol, Robert D. Cardiff, Senthil K. Muthuswamy

Cancer Res. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Cancer Res. 2014 Jun 1; 74(11): 3180–3194. Published online 2014 Mar 24. doi: 10.1158/0008-5472.CAN-13-3415

PMCID:: PMC4096808

Abstract Article PDF–1.3M

Select item 372484712.

Mutations in Planar Cell Polarity Gene SCRIB Are Associated with Spina Bifida

Yunping Lei, Huiping Zhu, Cody Duhon, Wei Yang, M. Elizabeth Ross, Gary M. Shaw, Richard H. Finnell

PLoS One. 2013; 8(7): e69262. Published online 2013 Jul 26. doi: 10.1371/journal.pone.0069262

PMCID:: PMC3724847

Abstract Article PDF–1.1M

Select item 312412113.

Aberrant Overexpression of the Cell Polarity Module Scribble in Human Cancer

Valentina Vaira, Alice Faversani, Takehiko Dohi, Marco Maggioni, Mario Nosotti, Delfina Tosi, Dario C. Altieri, Silvano Bosari

Am J Pathol. 2011 Jun; 178(6): 2478–2483. doi: 10.1016/j.ajpath.2011.02.028

PMCID:: PMC3124121

Abstract Article PDF–2.0M

Select item 295316614.

The ESEV PDZ-Binding Motif of the Avian Influenza A Virus NS1 Protein Protects Infected Cells from Apoptosis by Directly Targeting Scribble

Hongbing Liu, Lisa Golebiewski, Eugene C. Dow, Robert M. Krug, Ronald T. Javier, Andrew P. Rice

J Virol. 2010 Nov; 84(21): 11164–11174. Published online 2010 Aug 11. doi: 10.1128/JVI.01278-10

PMCID:: PMC2953166

Abstract Article PDF–2.1M

Select item 279787615.

Tumor Suppressor Scribble Regulates Assembly of Tight Junctions in the Intestinal Epithelium

Andrei I. Ivanov, Cheryl Young, Kyle Den Beste, Christopher T. Capaldo, Patrick O. Humbert, Patrick Brennwald, Charles A. Parkos, Asma Nusrat

Am J Pathol. 2010 Jan; 176(1): 134–145. doi: 10.2353/ajpath.2010.090220

PMCID:: PMC2797876

Abstract Article PDF–1.8M

Select item 239530216.

Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix

S Nakagawa, T Yano, K Nakagawa, S Takizawa, Y Suzuki, T Yasugi, J M Huibregtse, Y Taketani

Br J Cancer. 2004 Jan 12; 90(1): 194–199. Published online 2004 Jan 6. doi: 10.1038/sj.bjc.6601465

PMCID:: PMC2395302

Abstract Article PDF–222K

Select item 1115815017.

Human homolog of Drosophila tumor suppressor Scribble negatively regulates cell‐cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cells

Kazunori Nagasaka, Shunsuke Nakagawa, Tetsu Yano, Shin Takizawa, Yoko Matsumoto, Tetsushi Tsuruga, Keiichi Nakagawa, Takeo Minaguchi, Katsutoshi Oda, Osamu Hiraike‐Wada, Hajime Ooishi, Toshiharu Yasugi, Yuji Taketani

Cancer Sci. 2006 Nov; 97(11): 1217–1225. Published online 2006 Sep 5. doi: 10.1111/j.1349-7006.2006.00315.x

PMCID:: PMC11158150

Abstract Article PDF–581K

Select item 906172418.

Polarity protein SCRIB interacts with SLC3A2 to regulate proliferation and tamoxifen resistance in ER+ breast cancer

Yasuhiro Saito, Shiori Matsuda, Naomi Ohnishi, Keiko Endo, Sanae Ashitani, Maki Ohishi, Ayano Ueno, Masaru Tomita, Koji Ueda, Tomoyoshi Soga, Senthil K. Muthuswamy

Commun Biol. 2022; 5: 403. Published online 2022 May 2. doi: 10.1038/s42003-022-03363-3