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Select item 65100561.

Expression of TMEFF2 in Human Pancreatic Cancer Tissue and the Effects of TMEFF2 Knockdown on Cell, Proliferation, and Apoptosis in Human Pancreatic Cell Lines

Kailiang Li, Wenjing Gu, Jie Xu, Aikun Wang, Hongchao Han

Med Sci Monit. 2019; 25: 3238–3246. Published online 2019 May 2. doi: 10.12659/MSM.913974

PMCID:: PMC6510056

Abstract Article PDF–2.0M

Select item 65033802.

A TMEFF2-regulated cell cycle derived gene signature is prognostic of recurrence risk in prostate cancer

Constantin Georgescu, Joshua M. Corbin, Sandra Thibivilliers, Zachary D. Webb, Yan D. Zhao, Jan Koster, Kar-Ming Fung, Adam S. Asch, Jonathan D. Wren, Maria J. Ruiz-Echevarría

BMC Cancer. 2019; 19: 423. Published online 2019 May 6. doi: 10.1186/s12885-019-5592-6

PMCID:: PMC6503380

Abstract Article PDF–1.6M

Select item 58368823.

TMEFF2 shedding is regulated by oxidative stress and mediated by ADAMs and transmembrane serine proteases implicated in prostate cancer

Katarzyna Gaweł‐Bęben, Nazim Ali, Vincent Ellis, Gloria Velasco, Zaruhi Poghosyan, Ann Ager, Vera Knäuper

Cell Biol Int. 2018 Mar; 42(3): 273–280. Published online 2017 Aug 21. doi: 10.1002/cbin.10832

PMCID:: PMC5836882

Abstract Article PDF–872K

Select item 48322634.

Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma

Kim Andresen, Kirsten Muri Boberg, Hege Marie Vedeld, Hilde Honne, Peter Jebsen, Merete Hektoen, Christopher A. Wadsworth, Ole Petter Clausen, Knut E.A. Lundin, Vemund Paulsen, Aksel Foss, Øystein Mathisen, Lars Aabakken, Erik Schrumpf, Ragnhild A. Lothe, Guro E. Lind

Hepatology. 2015 May; 61(5): 1651–1659. Published online 2015 Feb 24. doi: 10.1002/hep.27707

PMCID:: PMC4832263

Abstract Article PDF–538K

Select item 38878095.

Methylation of TMEFF2 Gene in Tissue and Serum DNA from Patients with Non-Small Cell Lung Cancer

Su Man Lee, Jae Yong Park, Dong Sun Kim

Mol Cells. 2012 Aug 31; 34(2): 171–176. Published online 2012 Jul 18. doi: 10.1007/s10059-012-0083-5

PMCID:: PMC3887809

Abstract Article PDF–418K

Select item 37292556.

TMEFF2 modulates the AKT and ERK signaling pathways

Xiaofei Chen, Maria J Ruiz-Echevarría

Int J Biochem Mol Biol. 2013; 4(2): 83–94. Published online 2013 Jul 29.

PMCID:: PMC3729255

Abstract Article PDF–1023K

Select item 30912187.

The Tumor Suppressor Activity of the Transmembrane Protein with Epidermal Growth Factor and Two Follistatin Motifs 2 (TMEFF2) Correlates with Its Ability to Modulate Sarcosine Levels

Xiaofei Chen, Ryan Overcash, Thomas Green, Donald Hoffman, Adam S. Asch, Maria J. Ruiz-Echevarría

J Biol Chem. 2011 May 6; 286(18): 16091–16100. Published online 2011 Mar 10. doi: 10.1074/jbc.M110.193805

PMCID:: PMC3091218

Abstract Article PDF–1.2M

Select item 17908998.

Novel expressed sequences identified in a model of androgen independent prostate cancer

Steven N Quayle, Heidi Hare, Allen D Delaney, Martin Hirst, Dorothy Hwang, Jacqueline E Schein, Steven JM Jones, Marco A Marra, Marianne D Sadar

BMC Genomics. 2007; 8: 32. Published online 2007 Jan 26. doi: 10.1186/1471-2164-8-32

PMCID:: PMC1790899

Abstract Article PDF–461K

Select item 535939.

Clonal lymphoid progenitor cell lines expressing the BCR/ABL oncogene retain full differentiative function.

P A Scherle, K Dorshkind, O N Witte

Proc Natl Acad Sci U S A. 1990 Mar; 87(5): 1908–1912. doi: 10.1073/pnas.87.5.1908

PMCID:: PMC53593

Summary Page Browse PDF–1.0M

Select item 1457910.

HPP1: A transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers

Joanne Young, Kelli G. Biden, Lisa A. Simms, Phillip Huggard, Rozemary Karamatic, Helen J. Eyre, Grant R. Sutherland, Nirmitha Herath, Melissa Barker, Gregory J. Anderson, David R. Fitzpatrick, Grant A. Ramm, Jeremy R. Jass, Barbara A. Leggett

Proc Natl Acad Sci U S A. 2001 Jan 2; 98(1): 265–270. Published online 2000 Dec 19. doi: 10.1073/pnas.98.1.265

PMCID:: PMC14579

Abstract Article PDF–586K

Select item 748340611.

HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer

Abul Elahi, Abidemi Ajidahun, Leah Hendrick, Irina Getun, Leigh Ann Humphries, Jonathan Hernandez, David Shibata

J Surg Res. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: J Surg Res. 2020 Oct; 254: 183–190. Published online 2020 May 22. doi: 10.1016/j.jss.2020.04.010

PMCID:: PMC7483406

Abstract Article PDF–1.4M

Select item 387830712.

TMEFF2 AND SARDH COOPERATE TO MODULATE ONE CARBON METABOLISM AND INVASION OF PROSTATE CANCER CELLS

Thomas Green, Xiaofei Chen, Stephen Ryan, Adam S. Asch, Maria J. Ruiz-Echevarría

Prostate. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Prostate. 2013 Oct; 73(14): 10.1002/pros.22706. Published online 2013 Jul 3. doi: 10.1002/pros.22706

PMCID:: PMC3878307

Abstract Article PDF–2.0M

Select item 356621313.

Androgen Signaling Promotes Translation of TMEFF2 in Prostate Cancer Cells via Phosphorylation of the α Subunit of the Translation Initiation Factor 2

Ryan F. Overcash, Vesna A. Chappell, Thomas Green, Christopher B. Geyer, Adam S. Asch, Maria J. Ruiz-Echevarría

PLoS One. 2013; 8(2): e55257. Published online 2013 Feb 6. doi: 10.1371/journal.pone.0055257

PMCID:: PMC3566213

Abstract Article PDF–1.7M

Select item 308470914.

TMEFF2 Is a PDGF-AA Binding Protein with Methylation-Associated Gene Silencing in Multiple Cancer Types Including Glioma

Kui Lin, James R. Taylor, Jr., Thomas D. Wu, Johnny Gutierrez, J. Michael Elliott, Jean-Michel Vernes, Hartmut Koeppen, Heidi S. Phillips, Frederic J. de Sauvage, Y. Gloria Meng

PLoS One. 2011; 6(4): e18608. Published online 2011 Apr 29. doi: 10.1371/journal.pone.0018608

PMCID:: PMC3084709

Abstract Article PDF–891K

Select item 701157315.

MiR-323-3p Targeting Transmembrane Protein with EGF-Like and 2 Follistatin Domain (TMEFF2) Inhibits Human Lung Cancer A549 Cell Apoptosis by Regulation of AKT and ERK Signaling Pathways

Ji-min Fan, Zheng-rong Zheng, Yi-Ming Zeng, Xiao-yang Chen

Med Sci Monit. 2020; 26: e919454-1–e919454-11. Published online 2020 Feb 3. doi: 10.12659/MSM.919454

PMCID:: PMC7011573

Abstract Article PDF–2.5M

Select item 553310116.

Tomoregulin (TMEFF2) Binds Alzheimer’s Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity

Hyun-Seok Hong, Izumi Maezawa, Jitka Petrlova, Xiao-Yan Zhao, John C. Voss, Lee-Way Jin

J Alzheimers Dis. Author manuscript; available in PMC 2017 Jul 28.

Published in final edited form as: J Alzheimers Dis. 2015; 48(3): 731–743. doi: 10.3233/JAD-150318

PMCID:: PMC5533101

Abstract Article PDF–1.3M

Select item 429813017.

The Genetics of Hemoglobin A₂ Regulation in Sickle Cell Anemia

Paula J. Griffin, Paola Sebastiani, Heather Edward, Clinton T. Baldwin, Mark Gladwin, Victor Gordeuk, David H.K. Chui, Martin H. Steinberg

Am J Hematol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Am J Hematol. 2014 Nov; 89(11): 1019–1023. Published online 2014 Aug 4. doi: 10.1002/ajh.23811

PMCID:: PMC4298130

Abstract Article PDF–712K

Select item 412886218.

The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer

Jian Wang, Abul Elahi, Abidemi Ajidahun, Whalen Clark, Jonathan Hernandez, Alex Achille, Ji-hui Hao, Edward Seto, David Shibata

Cancer Biol Ther. 2014 Sep 1; 15(9): 1198–1207. Published online 2014 Jun 11. doi: 10.4161/cbt.29500

PMCID:: PMC4128862

Abstract Article PDF–2.4M

Select item 406593619.

Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions

Zhao-Hui Huang, Li-Hua Li, Fan Yang, Jin-Fu Wang

World J Gastroenterol. 2007 Feb 14; 13(6): 950–954. Published online 2007 Feb 14. doi: 10.3748/wjg.v13.i6.950

PMCID:: PMC4065936

Abstract Article PDF–1.6M

Select item 402170820.

THE TMEFF2 TUMOR SUPPRESSOR MODULATES INTEGRIN EXPRESSION, RHOA ACTIVATION AND MIGRATION OF PROSTATE CANCER CELLS

Xiaofei Chen, Joshua M. Corbin, Greg J. Tipton, Li V. Yang, Adam S. Asch, Maria J. Ruiz-Echevarría

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Jun; 1843(6): 1216–1224. Published online 2014 Mar 13. doi: 10.1016/j.bbamcr.2014.03.005