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Select item 106472211.

FKBP38 Regulates Self-Renewal and Survival of GBM Neurospheres

Aimee L. Dowling, Stuart Walbridge, Celine Ertekin, Sriya Namagiri, Krystal Camacho, Ashis Chowdhury, Jean-Paul Bryant, Eric Kohut, John D. Heiss, Desmond A. Brown, Sangamesh G. Kumbar, Yeshavanth Kumar Banasavadi-Siddegowda

Cells. 2023 Nov; 12(21): 2562. Published online 2023 Nov 2. doi: 10.3390/cells12212562

PMCID:: PMC10647221

Abstract Article PDF–2.7M

Select item 53444192.

The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90

Katie L. I. M. Blundell, Mohinder Pal, S. Mark Roe, Laurence H. Pearl, Chrisostomos Prodromou

PLoS One. 2017; 12(3): e0173543. Published online 2017 Mar 9. doi: 10.1371/journal.pone.0173543

PMCID:: PMC5344419

Abstract Article PDF–1.7M

Select item 38048613.

Functional role of the flexible N-terminal extension of FKBP38 in catalysis

CongBao Kang, Hong Ye, Joel Chia, Bo-Hwa Choi, Sirano Dhe-Paganon, Bernd Simon, Ulrike Schütz, Michael Sattler, Ho Sup Yoon

Sci Rep. 2013; 3: 2985. Published online 2013 Oct 22. doi: 10.1038/srep02985

PMCID:: PMC3804861

Abstract Article PDF–1.9M

Select item 31909974.

Phosphatidic Acid Activates Mammalian Target of Rapamycin Complex 1 (mTORC1) Kinase by Displacing FK506 Binding Protein 38 (FKBP38) and Exerting an Allosteric Effect

Mee-Sup Yoon, Yuting Sun, Edwin Arauz, Yu Jiang, Jie Chen

J Biol Chem. 2011 Aug 26; 286(34): 29568–29574. Published online 2011 Jul 7. doi: 10.1074/jbc.M111.262816

PMCID:: PMC3190997

Abstract Article PDF–857K

Select item 27151705.

Characterization of a Bcl-X_L-Interacting Protein FKBP8 and Its Splice Variant in Human RPE Cells

Yan Chen, Paul Sternberg, Jiyang Cai

Invest Ophthalmol Vis Sci. Author manuscript; available in PMC 2009 Jul 24.

Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 Apr; 49(4): 1721–1727. doi: 10.1167/iovs.07-1121

PMCID:: PMC2715170

Abstract Article PDF–659K

Select item 97427726.

Fkbp38基因缺失导致小鼠早发性卵巢功能不全：基于激活mTOR通路并诱导细胞凋亡

周玉霞, 赵茴茴, 帅领, 佘加杰, 刁瑞英, 汪丽萍

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Nov 20; 42(11): 1611–1617. Chinese. doi: 10.12122/j.issn.1673-4254.2022.11.04

PMCID:: PMC9742772

Abstract Article PDF–2.3M

Select item 63208027.

FKBP8 Enhances Protein Stability of the CLC-1 Chloride Channel at the Plasma Membrane

Yi-Jheng Peng, Yi-Ching Lee, Ssu-Ju Fu, Yun-Chia Chien, Yi-Fan Liao, Tsung-Yu Chen, Chung-Jiuan Jeng, Chih-Yung Tang

Int J Mol Sci. 2018 Dec; 19(12): 3783. Published online 2018 Nov 28. doi: 10.3390/ijms19123783

PMCID:: PMC6320802

Abstract Article PDF–3.8M

Select item 54520398.

FKBP8 recruits LC3A to mediate Parkin‐independent mitophagy

Zambarlal Bhujabal, Åsa B Birgisdottir, Eva Sjøttem, Hanne B Brenne, Aud Øvervatn, Sabrina Habisov, Vladimir Kirkin, Trond Lamark, Terje Johansen

EMBO Rep. 2017 Jun; 18(6): 947–961. Published online 2017 Apr 5. doi: 10.15252/embr.201643147

PMCID:: PMC5452039

Abstract Article PDF–2.9M

Select item 33811529.

FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability

Darren M. Hutt, Daniela Martino Roth, Monica A. Chalfant, Robert T. Youker, Jeanne Matteson, Jeffrey L. Brodsky, William E. Balch

J Biol Chem. 2012 Jun 22; 287(26): 21914–21925. Published online 2012 Apr 2. doi: 10.1074/jbc.M112.339788

PMCID:: PMC3381152

Abstract Article PDF–2.3M

Select item 336600110.

The FKBP38 Catalytic Domain Binds to Bcl-2 via a Charge-sensitive Loop

Katja Haupt, Günther Jahreis, Miriam Linnert, Mitcheell Maestre-Martínez, Miroslav Malešević, Arndt Pechstein, Frank Edlich, Christian Lücke

J Biol Chem. 2012 Jun 1; 287(23): 19665–19673. Published online 2012 Apr 20. doi: 10.1074/jbc.M111.317214

PMCID:: PMC3366001

Abstract Article PDF–2.2M

Select item 323485611.

FKBP38 Peptidylprolyl Isomerase Promotes the Folding of Cystic Fibrosis Transmembrane Conductance Regulator in the Endoplasmic Reticulum

Yeshavanth K. Banasavadi-Siddegowda, Junbo Mai, Yifei Fan, Sumit Bhattacharya, David R. Giovannucci, Edwin R. Sanchez, Gunter Fischer, Xiaodong Wang

J Biol Chem. 2011 Dec 16; 286(50): 43071–43080. Published online 2011 Oct 26. doi: 10.1074/jbc.M111.269993

PMCID:: PMC3234856

Abstract Article PDF–3.5M

Select item 284322612.

FKBP38 Protects Bcl-2 from Caspase-dependent Degradation

Bo-Hwa Choi, Lin Feng, Ho Sup Yoon

J Biol Chem. 2010 Mar 26; 285(13): 9770–9779. Published online 2010 Feb 5. doi: 10.1074/jbc.M109.032466

PMCID:: PMC2843226

Abstract Article PDF–3.1M

Select item 266214213.

Re-evaluating the Roles of Proposed Modulators of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling

Xuemin Wang, Bruno D. Fonseca, Hua Tang, Rui Liu, Androulla Elia, Michael J. Clemens, Ulrich-Axel Bommer, Christopher G. Proud

J Biol Chem. 2008 Nov 7; 283(45): 30482–30492. doi: 10.1074/jbc.M803348200

PMCID:: PMC2662142

Abstract Article PDF–1.0M

Select item 226845014.

A Single-Amino-Acid Mutation in Hepatitis C Virus NS5A Disrupting FKBP8 Interaction Impairs Viral Replication

Toru Okamoto, Hiroko Omori, Yuuki Kaname, Takayuki Abe, Yorihiro Nishimura, Tetsuro Suzuki, Tatsuo Miyamura, Tamotsu Yoshimori, Kohji Moriishi, Yoshiharu Matsuura

J Virol. 2008 Apr; 82(7): 3480–3489. Published online 2008 Jan 23. doi: 10.1128/JVI.02253-07

PMCID:: PMC2268450

Abstract Article PDF–817K

Select item 1109163015.

GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis

Tianfeng Dang, Jieqing Yu, Yanqing Yu, Junjie Jiang, Yang Shi, Simin Yu, Congli Peng, Xiang Min, Yuanping Xiong, Ping Long, Wensheng Zhou, Daofeng Dai

Cancer Biomark. 2024; 39(4): 349–360. Prepublished online 2023 Dec 19. Published online 2024 Apr 15. doi: 10.3233/CBM-230220

PMCID:: PMC11091630

Abstract Article PDF–9.2M

Select item 464495216.

Involvement of FKBP6 in hepatitis C virus replication

Hirotake Kasai, Kunihiro Kawakami, Hiromasa Yokoe, Kentaro Yoshimura, Masanori Matsuda, Jun Yasumoto, Shinya Maekawa, Atsuya Yamashita, Tomohisa Tanaka, Masanori Ikeda, Nobuyuki Kato, Toru Okamoto, Yoshiharu Matsuura, Naoya Sakamoto, Nobuyuki Enomoto, Sen Takeda, Hideki Fujii, Masayoshi Tsubuki, Masami Kusunoki, Kohji Moriishi

Sci Rep. 2015; 5: 16699. Published online 2015 Nov 16. doi: 10.1038/srep16699

PMCID:: PMC4644952

Abstract Article PDF–1.9M

Select item 381498617.

Lysophosphatidic Acid Acyltransferase Beta Regulates mTOR Signaling

Michelle A. Blaskovich, Vimala Yendluri, Harshani R. Lawrence, Nicholas J. Lawrence, Saïd M. Sebti, Gregory M. Springett

PLoS One. 2013; 8(10): e78632. Published online 2013 Oct 31. doi: 10.1371/journal.pone.0078632

PMCID:: PMC3814986

Abstract Article PDF–2.3M

Select item 253380218.

The Switch I Region of Rheb Is Critical for Its Interaction with FKBP38

Dongzhu Ma, Xiaochun Bai, Shuguang Guo, Yu Jiang

J Biol Chem. 2008 Sep 19; 283(38): 25963–25970. doi: 10.1074/jbc.M802356200

PMCID:: PMC2533802

Abstract Article PDF–915K

Select item 997757419.

The tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease

Li Zuo, Wei-Ting Kuo, Feng Cao, Sandra D. Chanez-Paredes, Daniel Zeve, Prabhath Mannam, Léa Jean-François, Anne Day, W Vallen Graham, Yan Y. Sweat, Nitesh Shashikanth, David T. Breault, Jerrold R. Turner

Gut. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Gut. 2023 May; 72(5): 870–881. Published online 2022 May 10. doi: 10.1136/gutjnl-2021-326534

PMCID:: PMC9977574

Abstract Article PDF–5.2M

Select item 764571520.

FKBP8 variants are risk factors for spina bifida

Tian Tian, Xuanye Cao, Sung-Eun Kim, Ying Linda Lin, John W Steele, Robert M Cabrera, Menuka Karki, Wei Yang, Nicholas J Marini, Ethan N Hoffman, Xiao Han, Cindy Hu, Linlin Wang, Bogdan J Wlodarczyk, Gary M Shaw, Aiguo Ren, Richard H Finnell, Yunping Lei

Hum Mol Genet. 2020 Sep 15; 29(18): 3132–3144. Published online 2020 Sep 24. doi: 10.1093/hmg/ddaa211