PMC Links for Gene (Select 26353) - PMC

Margherita Piccolella, Valeria Crippa, Riccardo Cristofani, Paola Rusmini, Mariarita Galbiati, Maria Elena Cicardi, Marco Meroni, Nicola Ferri, Federica F. Morelli, Serena Carra, Elio Messi, Angelo Poletti

Oncotarget. 2017 Feb 7; 8(6): 10400–10415. Published online 2017 Jan 2. doi: 10.18632/oncotarget.14422

PMCID:: PMC5354667

Abstract Article PDF–8.6M

Select item 47853664.

Transcriptional induction of the heat shock protein B8 mediates the clearance of misfolded proteins responsible for motor neuron diseases

Valeria Crippa, Vito G. D’Agostino, Riccardo Cristofani, Paola Rusmini, Maria E. Cicardi, Elio Messi, Rosa Loffredo, Michael Pancher, Margherita Piccolella, Mariarita Galbiati, Marco Meroni, Cristina Cereda, Serena Carra, Alessandro Provenzani, Angelo Poletti

Sci Rep. 2016; 6: 22827. Published online 2016 Mar 10. doi: 10.1038/srep22827

PMCID:: PMC4785366

Abstract Article PDF–2.3M

Select item 47760895.

Mutations in HSPB8 causing a new phenotype of distal myopathy and motor neuropathy

Roula Ghaoui, Johanna Palmio, Janice Brewer, Monkol Lek, Merrilee Needham, Anni Evilä, Peter Hackman, Per-Harald Jonson, Sini Penttilä, Anna Vihola, Sanna Huovinen, Mikaela Lindfors, Ryan L. Davis, Leigh Waddell, Simran Kaur, Con Yiannikas, Kathryn North, Nigel Clarke, Daniel G. MacArthur, Carolyn M. Sue, Bjarne Udd

Neurology. 2016 Jan 26; 86(4): 391–398. doi: 10.1212/WNL.0000000000002324

Correction in:: Neurology. 2016 Mar 15; 86(11): 1077.

PMCID:: PMC4776089

Abstract Article PDF–910K

Select item 41716276.

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells

Mohamed-Amine Hamouda, Nathalie Belhacene, Alexandre Puissant, Pascal Colosetti, Guillaume Robert, Arnaud Jacquel, Bernard Mari, Patrick Auberger, Frederic Luciano

Oncotarget. 2014 Aug; 5(15): 6252–6266. Published online 2014 Jul 9. doi: 10.18632/oncotarget.2193

PMCID:: PMC4171627

Abstract Article PDF–2.0M

Select item 34346667.

Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways

C C Smith, K S Lee, B Li, J M Laing, J Hersl, M Shvartsbeyn, L Aurelian

Cell Death Dis. 2012 Aug; 3(8): e371. Published online 2012 Aug 16. doi: 10.1038/cddis.2012.108

PMCID:: PMC3434666

Abstract Article

Select item 85105808.

HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain

Edgar E Boczek, Julius Fürsch, Marie Laura Niedermeier, Louise Jawerth, Marcus Jahnel, Martine Ruer-Gruß, Kai-Michael Kammer, Peter Heid, Laura Mediani, Jie Wang, Xiao Yan, Andrej Pozniakovski, Ina Poser, Daniel Mateju, Lars Hubatsch, Serena Carra, Simon Alberti, Anthony A Hyman, Florian Stengel

eLife. 2021; 10: e69377. Published online 2021 Sep 6. doi: 10.7554/eLife.69377

PMCID:: PMC8510580

Abstract Article PDF–3.6M

Select item 81974199.

Small heat shock protein 22 kDa can modulate the aggregation and liquid–liquid phase separation behavior of tau

April L. Darling, Jan Dahrendorff, Stefan G. Creodore, Chad A. Dickey, Laura J. Blair, Vladimir N. Uversky

Protein Sci. 2021 Jul; 30(7): 1350–1359. Published online 2021 Mar 15. doi: 10.1002/pro.4060

PMCID:: PMC8197419

Abstract Article PDF–5.2M

Select item 570511810.

Heat shock proteins HSPB8 and DNAJC5B have HCV antiviral activity

Ana Claudia Silva Braga, Bruno Moreira Carneiro, Mariana Nogueira Batista, Mônica Mayumi Akinaga, Cíntia Bittar, Paula Rahal

PLoS One. 2017; 12(11): e0188467. Published online 2017 Nov 28. doi: 10.1371/journal.pone.0188467

PMCID:: PMC5705118

Abstract Article PDF–2.0M

Select item 546503211.

Fine-tuning of actin dynamics by the HSPB8-BAG3 chaperone complex facilitates cytokinesis and contributes to its impact on cell division

Alice Anaïs Varlet, Margit Fuchs, Carole Luthold, Herman Lambert, Jacques Landry, Josée N. Lavoie

Cell Stress Chaperones. 2017 Jul; 22(4): 553–567. Published online 2017 Mar 8. doi: 10.1007/s12192-017-0780-2

PMCID:: PMC5465032

Abstract Article PDF–7.4M

Select item 317871512.

HSP22 (HSPB8/H11) KNOCKDOWN INDUCES SAM68 EXPRESSION AND STIMULATES PROLIFERATION OF GLIOBLASTOMA CELLS

Suhasini Modem, Kannagi Chinnakannu, Uma Bai, G. Prem-Veer Reddy, Thipparthi R Reddy

J Cell Physiol. Author manuscript; available in PMC 2012 Nov 1.

Published in final edited form as: J Cell Physiol. 2011 Nov; 226(11): 2747–2751. doi: 10.1002/jcp.22868

PMCID:: PMC3178715

Abstract Article PDF–646K

Select item 300661413.

Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3)

Xiankui Sun, Jean-Marc Fontaine, Adam D. Hoppe, Serena Carra, Cheryl DeGuzman, Jody L. Martin, Stephanie Simon, Patrick Vicart, Michael J. Welsh, Jacques Landry, Rainer Benndorf

Cell Stress Chaperones. 2010 Sep; 15(5): 567–582. Published online 2010 Feb 17. doi: 10.1007/s12192-010-0169-y

PMCID:: PMC3006614

Abstract Article PDF–697K

Select item 264335514.

Overload of the heat shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of Transforming Growth Factor β activated kinase 1 (TAK1)

Baiquan Li, Cynthia C. Smith, Jennifer M. Laing, Michael D. Gober, Ling Liu, Laure Aurelian

Oncogene. Author manuscript; available in PMC 2009 Feb 17.

Published in final edited form as: Oncogene. 2007 May 24; 26(24): 3521–3531. Published online 2006 Dec 18. doi: 10.1038/sj.onc.1210145

PMCID:: PMC2643355

Abstract Article PDF–1.8M

Select item 213479315.

Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor– positive breast cancer cells

Xiankui Sun, Jean-Marc Fontaine, Ingrid Bartl, Babak Behnam, Michael J. Welsh, Rainer Benndorf

Cell Stress Chaperones. 2007 Dec; 12(4): 307–319. doi: 10.1379/CSC-276.1

PMCID:: PMC2134793

Abstract Article PDF–438K

Select item 743203516.

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

Jack M. Webster, April L. Darling, Taylor A. Sanders, Danielle M. Blazier, Yamile Vidal-Aguiar, David Beaulieu-Abdelahad, Drew G. Plemmons, Shannon E. Hill, Vladimir N. Uversky, Paula C. Bickford, Chad A. Dickey, Laura J. Blair

Int J Mol Sci. 2020 Aug; 21(15): 5442. Published online 2020 Jul 30. doi: 10.3390/ijms21155442

PMCID:: PMC7432035

Abstract Article PDF–4.0M

Select item 461973817.

A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis

Margit Fuchs, Carole Luthold, Solenn M. Guilbert, Alice Anaïs Varlet, Herman Lambert, Alexandra Jetté, Sabine Elowe, Jacques Landry, Josée N. Lavoie

PLoS Genet. 2015 Oct; 11(10): e1005582. Published online 2015 Oct 23. doi: 10.1371/journal.pgen.1005582

PMCID:: PMC4619738

Abstract Article PDF–7.1M

Select item 1043372918.

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

Mena Abdel-Nour, Leticia A. M. Carneiro, Jeffrey Downey, Jessica Tsalikis, Ahmed Outlioua, Dave Prescott, Leandro Silva Da Costa, Elise S. Hovingh, Armin Farahvash, Ryan G. Gaudet, Raphael Molinaro, Rob van Dalen, Charles C. Y. Lau, Farshad C. Azimi, Nichole K. Escalante, Aaron Trotman-Grant, Jeffrey E. Lee, Scott D. Gray-Owen, Maziar Divangahi, Jane-Jane Chen, Dana J. Philpott, Damien Arnoult, Stephen E. Girardin

Science. Author manuscript; available in PMC 2023 Aug 17.

Published in final edited form as: Science. 2019 Jul 5; 365(6448): eaaw4144. doi: 10.1126/science.aaw4144

PMCID:: PMC10433729

Abstract Article PDF–2.2M

Select item 759165819.

BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes

Laura Mediani, Veronica Galli, Arianna Dorotea Carrà, Ilaria Bigi, Jonathan Vinet, Massimo Ganassi, Francesco Antoniani, Tatiana Tiago, Marco Cimino, Daniel Mateju, Cristina Cereda, Orietta Pansarasa, Simon Alberti, Jessica Mandrioli, Serena Carra

Cell Stress Chaperones. 2020 Nov; 25(6): 1045–1058. Published online 2020 Jul 21. doi: 10.1007/s12192-020-01141-w

PMCID:: PMC7591658

Abstract Article PDF–9.0M

Select item 546503020.

An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8

Federica F. Morelli, Laura Mediani, Lonneke Heldens, Jessika Bertacchini, Ilaria Bigi, Arianna Dorotea Carrà, Jonathan Vinet, Serena Carra

Cell Stress Chaperones. 2017 Jul; 22(4): 531–540. Published online 2017 Feb 8. doi: 10.1007/s12192-017-0769-x

PMCID:: PMC5465030

Abstract Article PDF–1.2M

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