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Select item 110695331.

Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow

Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

Nat Commun. 2024; 15: 3769. Published online 2024 May 4. doi: 10.1038/s41467-024-48255-8

PMCID:: PMC11069533

Abstract Article PDF–41M

Select item 105908672.

ERRα fosters running endurance by driving myofiber aerobic transformation and fuel efficiency

Hui Xia, Charlotte Scholtes, Catherine R. Dufour, Christina Guluzian, Vincent Giguère

Mol Metab. 2023 Dec; 78: 101814. Published online 2023 Oct 5. doi: 10.1016/j.molmet.2023.101814

PMCID:: PMC10590867

Abstract Article PDF–4.2M

Select item 92670153.

Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCD_cl1 Cells

Anna Keppner, Darko Maric, Ilaria Maria Christina Orlando, Laurent Falquet, Edith Hummler, David Hoogewijs

Int J Mol Sci. 2022 Jul; 23(13): 7262. Published online 2022 Jun 30. doi: 10.3390/ijms23137262

PMCID:: PMC9267015

Abstract Article PDF–3.0M

Select item 92593694.

The nuclear receptor ESRRA protects from kidney disease by coupling metabolism and differentiation

Poonam Dhillon, Jihwan Park, Carmen Hurtado del Pozo, Lingzhi Li, Tomohito Doke, Shizheng Huang, Juanjuan Zhao, Hyun Mi Kang, Rojesh Shrestra, Michael S. Balzer, Shatakshee Chatterjee, Patricia Prado, Seung Yub Han, Hongbo Liu, Xin Sheng, Pieterjan Dierickx, Kirill Batmanov, Juan P. Romero, Felipe Prósper, Mingyao Li, Liming Pei, Junhyong Kim, Nuria Montserrat, Katalin Susztak

Cell Metab. Author manuscript; available in PMC 2022 Jul 6.

Published in final edited form as: Cell Metab. 2021 Feb 2; 33(2): 379–394.e8. Published online 2020 Dec 9. doi: 10.1016/j.cmet.2020.11.011

PMCID:: PMC9259369

Abstract Article PDF–3.1M

Select item 89160975.

LOSS OF ESTROGEN-RELATED RECEPTOR ALPHA DISRUPTS VENTRAL-STRIATAL SYNAPTIC FUNCTION IN FEMALE MICE

HÉCTOR DE JESÚS-CORTÉS, YUAN LU, RACHEL M. ANDERSON, MICHAEL Z. KHAN, VARUN NATH, LATISHA MCDANIEL, MICHAEL LUTTER, JASON J. RADLEY, ANDREW A. PIEPER, HUXING CUI

Neuroscience. Author manuscript; available in PMC 2022 Mar 11.

Published in final edited form as: Neuroscience. 2016 Aug 4; 329: 66–73. Published online 2016 May 4. doi: 10.1016/j.neuroscience.2016.04.054

PMCID:: PMC8916097

Abstract Article PDF–1.2M

Select item 85259356.

ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota

Sup Kim, June-Young Lee, Seul Gi Shin, Jin Kyung Kim, Prashanta Silwal, Young Jae Kim, Na-Ri Shin, Pil Soo Kim, Minho Won, Sang-Hee Lee, Soo Yeon Kim, Miwa Sasai, Masahiro Yamamoto, Jin-Man Kim, Jin-Woo Bae, Eun-Kyeong Jo

Autophagy. 2021; 17(10): 2856–2875. Published online 2020 Dec 15. doi: 10.1080/15548627.2020.1847460

PMCID:: PMC8525935

Abstract Article PDF–11M

Select item 75326827.

Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development

Meng Yang, Qingli Liu, Tongling Huang, Wenjuan Tan, Linbing Qu, Tianke Chen, Haobo Pan, Ling Chen, Jinsong Liu, Chi-Wai Wong, William W. Lu, Min Guan

Theranostics. 2020; 10(24): 10874–10891. Published online 2020 Aug 29. doi: 10.7150/thno.47037

PMCID:: PMC7532682

Abstract Article PDF–4.0M

Select item 63795838.

Loss of Estrogen-Related Receptor Alpha Facilitates Angiogenesis in Endothelial Cells

Neah Likhite, Vikas Yadav, Eric J. Milliman, Danesh H. Sopariwala, Sabina Lorca, Nithya P. Narayana, Megha Sheth, Erin L. Reineke, Vincent Giguère, Vihang Narkar

Mol Cell Biol. 2019 Mar 1; 39(5): e00411-18. Prepublished online 2019 Jan 2. Published online 2019 Feb 15. doi: 10.1128/MCB.00411-18

PMCID:: PMC6379583

Abstract Article PDF–4.7M

Select item 58465649.

ESRRA (estrogen-related receptor α) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense

Soo Yeon Kim, Chul-Su Yang, Hye-Mi Lee, Jin Kyung Kim, Yi-Sak Kim, Ye-Ram Kim, Jae-Sung Kim, Tae Sung Kim, Jae-Min Yuk, Catherine Rosa Dufour, Sang-Hee Lee, Jin-Man Kim, Hueng-Sik Choi, Vincent Giguère, Eun-Kyeong Jo

Autophagy. 2018; 14(1): 152–168. Published online 2017 Sep 1. doi: 10.1080/15548627.2017.1339001

PMCID:: PMC5846564

Abstract Article PDF–2.0M

Select item 545332910.

Transcriptional regulatory dynamics drive coordinated metabolic and neural response to social challenge in mice

Michael C. Saul, Christopher H. Seward, Joseph M. Troy, Huimin Zhang, Laura G. Sloofman, Xiaochen Lu, Patricia A. Weisner, Derek Caetano-Anolles, Hao Sun, Sihai Dave Zhao, Sriram Chandrasekaran, Saurabh Sinha, Lisa Stubbs

Genome Res. 2017 Jun; 27(6): 959–972. doi: 10.1101/gr.214221.116

PMCID:: PMC5453329

Abstract Article PDF–1.5M

Select item 542815011.

Physiological Genomics Identifies Estrogen-Related Receptor α as a Regulator of Renal Sodium and Potassium Homeostasis and the Renin-Angiotensin Pathway

Annie M. Tremblay, Catherine R. Dufour, Majid Ghahremani, Timothy L. Reudelhuber, Vincent Giguère

Mol Endocrinol. January 1, 2010; 24(1): 22–32. doi: 10.1210/me.2009-0254

PMCID:: PMC5428150

Abstract Article

Select item 541478112.

Marie-Claude Perry, Catherine R. Dufour, Ingrid S. Tam, Wafa B'chir, Vincent Giguère

Mol Endocrinol. 2014 Dec; 28(12): 2060–2071. Published online 2014 Oct 31. doi: 10.1210/me.2014-1281

PMCID:: PMC5414781

Abstract Article

Select item 513335413.

Complementary Roles of Estrogen-Related Receptors in Brown Adipocyte Thermogenic Function

Marin L. Gantner, Bethany C. Hazen, Elodie Eury, Erin L. Brown, Anastasia Kralli

Endocrinology. 2016 Dec; 157(12): 4770–4781. Published online 2016 Oct 20. doi: 10.1210/en.2016-1767

PMCID:: PMC5133354

Abstract Article

Select item 483365814.

ERRα Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer

Sunghee Park, Ching-yi Chang, Rachid Safi, Xiaojing Liu, Robert Baldi, Jeff S. Jasper, Grace R. Anderson, Tingyu Liu, Jeffrey C. Rathmell, Mark W. Dewhirst, Kris C. Wood, Jason W. Locasale, Donald P. McDonnell

Cell Rep. Author manuscript; available in PMC 2016 Apr 15.

Published in final edited form as: Cell Rep. 2016 Apr 12; 15(2): 323–335. Published online 2016 Mar 31. doi: 10.1016/j.celrep.2016.03.026

PMCID:: PMC4833658

Abstract Article PDF–2.6M

Select item 478507815.

Ligand Activation of ERRα by Cholesterol Mediates Statin and Bisphosphonate Effects

Wei Wei, Adam G. Schwaid, Xueqian Wang, Xunde Wang, Shili Chen, Qian Chu, Alan Saghatelian, Yihong Wan

Cell Metab. Author manuscript; available in PMC 2017 Mar 8.

Published in final edited form as: Cell Metab. 2016 Mar 8; 23(3): 479–491. Published online 2016 Jan 14. doi: 10.1016/j.cmet.2015.12.010

PMCID:: PMC4785078

Abstract Article PDF–3.2M

Select item 451646416.

Suppressing the activity of ERRα in 3T3-L1 adipocytes reduces mitochondrial biogenesis but enhances glycolysis and basal glucose uptake

Yaohui Nie, Chiwai Wong

J Cell Mol Med. 2009 Sep; 13(9b): 3051–3060. Published online 2008 Jun 9. doi: 10.1111/j.1582-4934.2008.00382.x

PMCID:: PMC4516464

Abstract Article PDF–1.1M

Select item 444032917.

Behavioral Disturbances in Estrogen-Related Receptor alpha-Null Mice

Huxing Cui, Yuan Lu, Michael Z. Khan, Rachel M. Anderson, Latisha McDaniel, Hannah E. Wilson, Terry C. Yin, Jason J. Radley, Andrew A. Pieper, Michael Lutter

Cell Rep. Author manuscript; available in PMC 2016 Apr 21.

Published in final edited form as: Cell Rep. 2015 Apr 21; 11(3): 344–350. Published online 2015 Apr 9. doi: 10.1016/j.celrep.2015.03.032

PMCID:: PMC4440329

Abstract Article PDF–1.1M

Select item 392968218.

Samuel LaBarge, Marisa McDonald, Leslie Smith-Powell, Johan Auwerx, Janice M. Huss

FASEB J. 2014 Mar; 28(3): 1082–1097. doi: 10.1096/fj.13-229211

PMCID:: PMC3929682

Abstract Article

Select item 381641719.

Loss of estrogen-related receptor α promotes hepatocarcinogenesis development via metabolic and inflammatory disturbances

Eui-Ju Hong, Marie-Pier Levasseur, Catherine R. Dufour, Marie-Claude Perry, Vincent Giguère

Proc Natl Acad Sci U S A. 2013 Oct 29; 110(44): 17975–17980. Published online 2013 Oct 14. doi: 10.1073/pnas.1315319110

PMCID:: PMC3816417

Abstract Article PDF–1009K

Select item 321501220.

Ryan D. Michalek, Valerie A. Gerriets, Amanda G. Nichols, Makoto Inoue, Dmitri Kazmin, Ching-Yi Chang, Mary A. Dwyer, Erik R. Nelson, Kristen N. Pollizzi, Olga Ilkayeva, Vincent Giguere, William J. Zuercher, Jonathan D. Powell, Mari L. Shinohara, Donald P. McDonnell, Jeffrey C. Rathmell

Proc Natl Acad Sci U S A. 2011 Nov 8; 108(45): 18348–18353. Published online 2011 Oct 31. doi: 10.1073/pnas.1108856108

PMCID:: PMC3215012

Abstract Article PDF–691K

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