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Items: 1 to 20 of 35

1.
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations
Jian Ren, Yazi Huang, Yeqing Ren, Tianqi Tu, Baoshan Qiu, Daosheng Ai, Zhanying Bi, Xue Bai, Fengzhi Li, Jun-Liszt Li, Xing-jun Chen, Ziyan Feng, Zongpei Guo, Jianfeng Lei, An Tian, Ziwei Cui, Volkhard Lindner, Ralf H Adams, Yibo Wang, Fei Zhao, Jakob Körbelin, Wenzhi Sun, Yilong Wang, Hongqi Zhang, Tao Hong, Woo-ping Ge
Brain. 2023 Sep; 146(9): 3634–3647. Published online 2023 Mar 30. doi: 10.1093/brain/awad104
PMCID:
PMC10473567
AbstractArticlePDF–1.5M
2.
Platelet MEKK3 regulates arterial thrombosis and myocardial infarct expansion in mice
Xuemei Fan, Conghui Wang, Panlai Shi, Wen Gao, Jianmin Gu, Yan Geng, Wenlong Yang, Ningbo Wu, Yang Wang, Yanyan Xu, Xue Chen, Lin Zhang, Kemin Wang, Bing Su, Junling Liu
Blood Adv. 2018 Jun 26; 2(12): 1439–1448. Published online 2018 Jun 25. doi: 10.1182/bloodadvances.2017015149
PMCID:
PMC6020810
AbstractArticlePDF–3.7M
3.
MEKK3 initiates TGFβ2-dependent EMT during endocardial cushion morphogenesis
Mark V. Stevens, Derrick M. Broka, Patti Parker, Elisa Rogowitz, Richard R. Vaillancourt, Todd D. Camenisch
Circ Res. Author manuscript; available in PMC 2009 Dec 5.
Published in final edited form as: Circ Res. 2008 Dec 5; 103(12): 1430–1440. Published online 2008 Nov 13. doi: 10.1161/CIRCRESAHA.108.180752
PMCID:
PMC2728220
AbstractArticlePDF–3.6M
4.
MEKK3 is required for lysophosphatidic acid-induced NF-κB activation
Wenjing Sun, Hongxiu Li, Yang Yu, Yihui Fan, Brian C. Grabiner, Renfang Mao, Ningling Ge, Hong Zhang, Songbin Fu, Xin Lin, Jianhua Yang
Cell Signal. Author manuscript; available in PMC 2010 Oct 1.
Published in final edited form as: Cell Signal. 2009 Oct; 21(10): 1488–1494. Published online 2009 May 22. doi: 10.1016/j.cellsig.2009.05.007
PMCID:
PMC2719299
AbstractArticlePDF–927K
5.
MEKK3 is essential for lipopolysaccharide-induced interleukin-6 and granulocyte–macrophage colony-stimulating factor production in macrophages
Kihwan Kim, Omar Duramad, Xiao-Feng Qin, Bing Su
Immunology. 2007 Feb; 120(2): 242–250. doi: 10.1111/j.1365-2567.2006.02495.x
PMCID:
PMC2265862
AbstractArticlePDF–731K
6.
MicroRNA-124 regulates the expression of MEKK3 in the inflammatory pathogenesis of Parkinson’s disease
Longping Yao, Yongyi Ye, Hengxu Mao, Fengfei Lu, Xiaozheng He, Guohui Lu, Shizhong Zhang
J Neuroinflammation. 2018; 15: 13. Published online 2018 Jan 12. doi: 10.1186/s12974-018-1053-4
PMCID:
PMC5767033
AbstractArticlePDF–3.8M
7.
MEKK3 Regulates IFN-γ Production in T Cells through the Rac1/2-Dependent MAPK Cascades
Xiaofang Wang, Fan Zhang, Fanping Chen, Dou Liu, Yi Zheng, Yongliang Zhang, Chen Dong, Bing Su
J Immunol. Author manuscript; available in PMC 2013 Nov 19.
Published in final edited form as: J Immunol. 2011 May 15; 186(10): 10.4049/jimmunol.1002127. Published online 2011 Apr 6. doi: 10.4049/jimmunol.1002127
PMCID:
PMC3833674
AbstractArticlePDF–1.5M
8.
The kinases MEKK2 and MEKK3 regulate Transforming Growth Factor-β-mediated helper T cell differentiation
Xing Chang, Fang Liu, Xiaofang Wang, Aiping Lin, Hongyu Zhao, Bing Su
Immunity. Author manuscript; available in PMC 2012 Feb 25.
Published in final edited form as: Immunity. 2011 Feb 25; 34(2): 201–212. Published online 2011 Feb 17. doi: 10.1016/j.immuni.2011.01.017
PMCID:
PMC3073014
AbstractArticlePDF–631K
9.
MEKK3 Is Essential for Lymphopenia-Induced T Cell Proliferation and Survival
Xiaofang Wang, Xing Chang, Valeria Facchinetti, Yuan Zhuang, Bing Su
J Immunol. Author manuscript; available in PMC 2010 Aug 18.
Published in final edited form as: J Immunol. 2009 Mar 15; 182(6): 3597–3608. doi: 10.4049/jimmunol.0803738
PMCID:
PMC2923428
AbstractArticlePDF–1.3M
10.
Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways
Dongyu Zhang, Valeria Facchinetti, Xiaofang Wang, Qiaojia Huang, Jun Qin, Bing Su
EMBO J. 2006 Jan 11; 25(1): 97–107. Published online 2005 Dec 15. doi: 10.1038/sj.emboj.7600913
PMCID:
PMC1356356
AbstractArticlePDF–263K
11.
Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice
Jaesung P. Choi, Matthew Foley, Zinan Zhou, Weng-Yew Wong, Naveena Gokoolparsadh, J. Simon C. Arthur, Dean Y. Li, Xiangjian Zheng
PLoS One. 2016; 11(8): e0160833. Published online 2016 Aug 11. doi: 10.1371/journal.pone.0160833
PMCID:
PMC4981389
AbstractArticlePDF–6.3M
12.
Vasculogenesis Driven by Bone Marrow-Derived Cells Is Essential for Growth of Ewing’s Sarcomas
Ling Yu, Bing Su, Mario Hollomon, Yong Deng, Valeria Facchinetti, Eugenie S. Kleinerman
Cancer Res. Author manuscript; available in PMC 2011 Feb 15.
Published in final edited form as: Cancer Res. 2010 Feb 15; 70(4): 1334–1343. Published online 2010 Feb 2. doi: 10.1158/0008-5472.CAN-09-2795
PMCID:
PMC2874750
AbstractArticlePDF–1.7M
13.
HOMEOSTATIC INTERACTIONS BETWEEN MEKK3 AND TAK1 INVOLVED IN NF-κB SIGNALING
Yuwei Di, Shitao Li, Lingyan Wang, Ye Zhang, Martin E. Dorf
Cell Signal. Author manuscript; available in PMC 2009 Apr 1.
Published in final edited form as: Cell Signal. 2008 Apr; 20(4): 705–713. Published online 2008 Jan 18. doi: 10.1016/j.cellsig.2007.12.007
PMCID:
PMC2362106
AbstractArticlePDF–1.2M
14.
Selective Activation of Mitogen-Activated Protein (MAP) Kinase Kinase 3 and p38α MAP Kinase Is Essential for Cyclic AMP-Dependent UCP1 Expression in Adipocytes
Jacques Robidoux, Wenhong Cao, Hui Quan, Kiefer W. Daniel, Fatiha Moukdar, Xu Bai, Lisa M. Floering, Sheila Collins
Mol Cell Biol. 2005 Jul; 25(13): 5466–5479. doi: 10.1128/MCB.25.13.5466-5479.2005
PMCID:
PMC1157000
AbstractArticlePDF–772K
15.
Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex
Oriana S. Fisher, Hanqiang Deng, Dou Liu, Ya Zhang, Rong Wei, Yong Deng, Fan Zhang, Angeliki Louvi, Benjamin E. Turk, Titus J. Boggon, Bing Su
Nat Commun. 2015; 6: 7937. Published online 2015 Aug 3. doi: 10.1038/ncomms8937
PMCID:
PMC4526114
AbstractArticlePDF–2.2M
16.
Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation
Barry Fong, Patricia H Watson, Andrew J Watson
BMC Dev Biol. 2007; 7: 2. Published online 2007 Jan 10. doi: 10.1186/1471-213X-7-2
PMCID:
PMC1781062
AbstractArticlePDF–1.2M
17.
TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development
Erdyni N. Tsitsikov, Khanh P. Phan, Yufeng Liu, Alla V. Tsytsykova, Mike Kinter, Lauren Selland, Lori Garman, Courtney Griffin, Ian F. Dunn
iScience. 2023 Aug 18; 26(8): 107474. Published online 2023 Jul 25. doi: 10.1016/j.isci.2023.107474
PMCID:
PMC10424150
AbstractArticlePDF–5.6M
18.
A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose-tissue inflammation in obesity
Eloy D. Hernandez, Sang Jun Lee, Ji Young Kim, Angeles Duran, Juan F. Linares, Tomoko Yajima, Timo D. Müller, Matthias H. Tschöp, Steven R. Smith, Maria T. Diaz-Meco, Jorge Moscat
Cell Metab. Author manuscript; available in PMC 2015 Sep 2.
Published in final edited form as: Cell Metab. 2014 Sep 2; 20(3): 499–511. Published online 2014 Jul 17. doi: 10.1016/j.cmet.2014.06.008
PMCID:
PMC4156534
AbstractArticlePDF–1.7M
19.
MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis
Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck, Jingwen Yu, Liang Liu, Yvonne Y. C. Yeap, Weiya Zhang, Feng Zhang, Yinghang Feng, Tiantian Ma, Yujie Wang, Dominic C. H. Ng, Xiaoyin Niu, Bing Su, Axel Behrens, Zhiheng Xu
PLoS Biol. 2018 Dec; 16(12): e2006613. Published online 2018 Dec 19. doi: 10.1371/journal.pbio.2006613
PMCID:
PMC6347294
AbstractArticlePDF–3.5M
20.
Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signaling
Zinan Zhou, Alan T. Tang, Weng-Yew Wong, Sharika Bamezai, Lauren M. Goddard, Robert Shenkar, Su Zhou, Jisheng Yang, Alexander C. Wright, Matthew Foley, J. Simon C. Arthur, Kevin J. Whitehead, Issam A. Awad, Dean Y. Li, Xiangjian Zheng, Mark L. Kahn
Nature. Author manuscript; available in PMC 2016 Sep 30.
Published in final edited form as: Nature. 2016 Apr 7; 532(7597): 122–126. Published online 2016 Mar 30. doi: 10.1038/nature17178
Correction in:
Nature. 2016 May 25; 536(7617): 488.
PMCID:
PMC4864035
AbstractArticlePDF–3.0M

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