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Select item 108997591.

Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs

Krystal C Johnson, Audrius Kilikevicius, Cristina Hofman, Jiaxin Hu, Yang Liu, Selina Aguilar, Jon Graswich, Yi Han, Tao Wang, Jill M Westcott, Rolf A Brekken, Lan Peng, Georgios Karagkounis, David R Corey

Nucleic Acids Res. 2024 Feb 28; 52(4): 1930–1952. Published online 2023 Dec 18. doi: 10.1093/nar/gkad1155

PMCID:: PMC10899759

Abstract Article PDF–4.2M

Select item 108489412.

Actin-dependent recruitment of AGO2 to the zonula adherens

Mary Catherine Bridges, Joyce Nair-Menon, Alyssa Risner, Douglas W. Jimenez, Amanda C. Daulagala, Christina Kingsley, Madison E. Davis, Antonis Kourtidis

Mol Biol Cell. 2023 Dec 1; 34(13): ar129. Published online 2023 Nov 13. doi: 10.1091/mbc.E22-03-0099-T

PMCID:: PMC10848941

Abstract Article PDF–27M

Select item 105149913.

Long non-coding RNA CASC7 is a promising serum biomarker for hepatocellular carcinoma

Ling Liao, Xia Chen, Hengliu Huang, Yuwei Li, Qing Huang, Zhen Song, Jie Luo, Tao Yuan, Shaoli Deng

BMC Gastroenterol. 2023; 23: 324. Published online 2023 Sep 21. doi: 10.1186/s12876-023-02961-7

PMCID:: PMC10514991

Abstract Article PDF–1.9M

Select item 102381254.

The RNA Interference Effector Protein Argonaute 2 Functions as a Restriction Factor Against SARS-CoV-2

Joaquin Lopez-Orozco, Nawell Fayad, Juveriya Qamar Khan, Alberto Felix-Lopez, Mohamed Elaish, Megha Rohamare, Maansi Sharma, Darryl Falzarano, Jerry Pelletier, Joyce Wilson, Tom C. Hobman, Anil Kumar

J Mol Biol. 2023 Jun 3 : 168170. doi: 10.1016/j.jmb.2023.168170 [Epub ahead of print]

PMCID:: PMC10238125

Abstract Article PDF–3.8M

Select item 92505335.

Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2

Sarah Willkomm, Leonhard Jakob, Kevin Kramm, Veronika Graus, Julia Neumeier, Gunter Meister, Dina Grohmann

Nat Commun. 2022; 13: 3825. Published online 2022 Jul 2. doi: 10.1038/s41467-022-31480-4

PMCID:: PMC9250533

Abstract Article PDF–7.9M

Select item 91547496.

Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release

Brianna Bibel, Elad Elkayam, Steve Silletti, Elizabeth A Komives, Leemor Joshua-Tor

eLife. 2022; 11: e76908. Published online 2022 May 31. doi: 10.7554/eLife.76908

PMCID:: PMC9154749

Abstract Article PDF–5.8M

Select item 86329327.

Critical role of backbone coordination in the mRNA recognition by RNA induced silencing complex

Lizhe Zhu, Hanlun Jiang, Siqin Cao, Ilona Christy Unarta, Xin Gao, Xuhui Huang

Commun Biol. 2021; 4: 1345. Published online 2021 Nov 30. doi: 10.1038/s42003-021-02822-7

PMCID:: PMC8632932

Abstract Article PDF–2.7M

Select item 82106328.

mRNA structural dynamics shape Argonaute-target interactions

Suzan Ruijtenberg, Stijn Sonneveld, Tao Ju Cui, Ive Logister, Dion de Steenwinkel, Yao Xiao, Ian J. MacRae, Chirlmin Joo, Marvin E. Tanenbaum

Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Jun 17.

Published in final edited form as: Nat Struct Mol Biol. 2020 Sep; 27(9): 790–801. Published online 2020 Jul 13. doi: 10.1038/s41594-020-0461-1

Correction in:: Nat Struct Mol Biol. 2021 Jun 4

PMCID:: PMC8210632

Abstract Article PDF–3.3M

Select item 81960639.

AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division

Vasiliki I. Pantazopoulou, Anastasios D. Delis, Stella Georgiou, Stamatis N. Pagakis, Vicky Filippa, Eleni Dragona, Ismini Kloukina, Elias Chatzitheodoridis, Jonel Trebicka, Athanassios D. Velentzas, Maja Thiele, Sarantis Gagos, Dimitris Thanos, Sofia Tseleni-Balafouta, Dimitrios J. Stravopodis, Ema Anastasiadou

Commun Biol. 2021; 4: 726. Published online 2021 Jun 11. doi: 10.1038/s42003-021-02130-0

PMCID:: PMC8196063

Abstract Article PDF–9.1M

Select item 808826510.

GW182 Proteins Restrict Extracellular Vesicle-Mediated Export of MicroRNAs in Mammalian Cancer Cells

Souvik Ghosh, Kamalika Mukherjee, Yogaditya Chakrabarty, Susanta Chatterjee, Bartika Ghoshal, Suvendra N. Bhattacharyya

Mol Cell Biol. 2021 May; 41(5): e00483-20. Prepublished online 2021 Mar 8. Published online 2021 Apr 22. doi: 10.1128/MCB.00483-20

PMCID:: PMC8088265

Abstract Article PDF–5.0M

Select item 767040311.

Germline AGO2 mutations impair RNA interference and human neurological development

Davor Lessel, Daniela M. Zeitler, Margot R. F. Reijnders, Andriy Kazantsev, Fatemeh Hassani Nia, Alexander Bartholomäus, Victoria Martens, Astrid Bruckmann, Veronika Graus, Allyn McConkie-Rosell, Marie McDonald, Bernarda Lozic, Ee-Shien Tan, Erica Gerkes, Jessika Johannsen, Jonas Denecke, Aida Telegrafi, Evelien Zonneveld-Huijssoon, Henny H. Lemmink, Breana W. M. Cham, Tanja Kovacevic, Linda Ramsdell, Kimberly Foss, Diana Le Duc, Diana Mitter, Steffen Syrbe, Andreas Merkenschlager, Margje Sinnema, Bianca Panis, Joanna Lazier, Matthew Osmond, Taila Hartley, Jeremie Mortreux, Tiffany Busa, Chantal Missirian, Pankaj Prasun, Sabine Lüttgen, Ilaria Mannucci, Ivana Lessel, Claudia Schob, Stefan Kindler, John Pappas, Rachel Rabin, Marjolein Willemsen, Thatjana Gardeitchik, Katharina Löhner, Patrick Rump, Kerith-Rae Dias, Carey-Anne Evans, Peter Ian Andrews, Tony Roscioli, Han G. Brunner, Chieko Chijiwa, M. E. Suzanne Lewis, Rami Abou Jamra, David A. Dyment, Kym M. Boycott, Alexander P. A. Stegmann, Christian Kubisch, Ene-Choo Tan, Ghayda M. Mirzaa, Kirsty McWalter, Tjitske Kleefstra, Rolph Pfundt, Zoya Ignatova, Gunter Meister, Hans-Jürgen Kreienkamp

Nat Commun. 2020; 11: 5797. Published online 2020 Nov 16. doi: 10.1038/s41467-020-19572-5

PMCID:: PMC7670403

Abstract Article PDF–2.2M

Select item 753370012.

Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides

Hirosha Geekiyanage, Shima Rayatpisheh, James A. Wohlschlegel, Robert Brown, Jr, Victor Ambros

Proc Natl Acad Sci U S A. 2020 Sep 29; 117(39): 24213–24223. Published online 2020 Sep 14. doi: 10.1073/pnas.2008323117

PMCID:: PMC7533700

Abstract Article PDF–1.5M

Select item 743290113.

Investigation of Strand-Selective Interaction of SNA-Modified siRNA with AGO2-MID

Yukiko Kamiya, Yuuki Takeyama, Tomonari Mizuno, Fuminori Satoh, Hiroyuki Asanuma

Int J Mol Sci. 2020 Aug; 21(15): 5218. Published online 2020 Jul 23. doi: 10.3390/ijms21155218

PMCID:: PMC7432901

Abstract Article PDF–2.0M

Select item 721051914.

Accumulation of AGO2 Facilitates Tumorigenesis of Human Hepatocellular Carcinoma

Yang Yang, Qi Mei

Biomed Res Int. 2020; 2020: 1631843. Published online 2020 Apr 30. doi: 10.1155/2020/1631843

PMCID:: PMC7210519

Abstract Article PDF–2.5M

Select item 716232415.

Biphasic regulation of RNA interference during rotavirus infection by modulation of Argonaute2

Urbi Mukhopadhyay, Shampa Chanda, Upayan Patra, Anupam Mukherjee, Satoshi Komoto, Mamta Chawla‐Sarkar

Cell Microbiol. 2019 Dec; 21(12): e13101. Published online 2019 Aug 26. doi: 10.1111/cmi.13101

PMCID:: PMC7162324

Abstract Article PDF–3.1M

Select item 676016116.

No evidence for viral small RNA production and antiviral function of Argonaute 2 in human cells

Susan Schuster, Gijs J. Overheul, Lisa Bauer, Frank J. M. van Kuppeveld, Ronald P. van Rij

Sci Rep. 2019; 9: 13752. Published online 2019 Sep 24. doi: 10.1038/s41598-019-50287-w

PMCID:: PMC6760161

Abstract Article PDF–2.6M

Select item 664257917.

Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer

M.C. Casey, A. Prakash, E. Holian, A. McGuire, O. Kalinina, A. Shalaby, C. Curran, M. Webber, G. Callagy, E. Bourke, M. J. Kerin, J. A. Brown

BMC Cancer. 2019; 19: 712. Published online 2019 Jul 19. doi: 10.1186/s12885-019-5884-x

PMCID:: PMC6642579

Abstract Article PDF–2.5M

Select item 660064518.

Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2

Jessica Sheu‐Gruttadauria, Yao Xiao, Luca FR Gebert, Ian J MacRae

EMBO J. 2019 Jul 1; 38(13): e101153. Published online 2019 Apr 26. doi: 10.15252/embj.2018101153

PMCID:: PMC6600645

Abstract Article PDF–1.9M

Select item 632585319.

Ago HITS-CLIP expands microRNA-mRNA interactions in nucleus and cytoplasm of gastric cancer cells

Xinyi Zhang, Bo Shen, Yalei Cui

BMC Cancer. 2019; 19: 29. Published online 2019 Jan 8. doi: 10.1186/s12885-018-5246-0

PMCID:: PMC6325853

Abstract Article PDF–2.5M

Select item 632513720.

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells

Teresa Bellissimo, Claudia Tito, Federica Ganci, Andrea Sacconi, Silvia Masciarelli, Giuseppe Di Martino, Natale Porta, Mirko Cirenza, Melissa Sorci, Luciana De Angelis, Paolo Rosa, Antonella Calogero, Alessandro Fatica, Vincenzo Petrozza, Giulia Fontemaggi, Giovanni Blandino, Francesco Fazi

Cell Death Dis. 2019 Jan; 10(1): 17. Published online 2019 Jan 8. doi: 10.1038/s41419-018-1267-5

PMCID:: PMC6325137

Abstract Article PDF–1.9M

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