PMC Links for Gene (Select 2752) - PMC

Links from Gene

Items: 1 to 20 of 94

<< First< Prev

Page of 5

Select item 100612881.

Single‐cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers

Jinfen Wei, Wenqi Yu, Juanzhi Chen, Guanda Huang, Lingjie Zhang, Zixi Chen, Meiling Hu, Xiaocheng Gong, Hongli Du

Mol Oncol. 2023 Apr; 17(4): 611–628. Published online 2023 Jan 21. doi: 10.1002/1878-0261.13373

PMCID:: PMC10061288

Abstract Article PDF–15M

Select item 100118362.

Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation

Nicolás Campolo, Mauricio Mastrogiovanni, Michele Mariotti, Federico M. Issoglio, Darío Estrin, Per Hägglund, Tilman Grune, Michael J. Davies, Silvina Bartesaghi, Rafael Radi

J Biol Chem. 2023 Mar; 299(3): 102941. Published online 2023 Jan 23. doi: 10.1016/j.jbc.2023.102941

PMCID:: PMC10011836

Abstract Article PDF–5.8M

Select item 98128103.

Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway

Do Thi Minh Xuan, Chung-Che Wu, Wei-Jan Wang, Hui-Ping Hsu, Hoang Dang Khoa Ta, Gangga Anuraga, Chung-Chieh Chiao, Chih-Yang Wang

Int J Med Sci. 2023; 20(1): 35–49. Published online 2023 Jan 1. doi: 10.7150/ijms.75625

PMCID:: PMC9812810

Abstract Article PDF–9.8M

Select item 85618134.

Crystal structure of N-terminal degron-truncated human glutamine synthetase

Min Fey Chek, Sun-Yong Kim, Tomoyuki Mori, Hisayuki Kojima, Toshio Hakoshima

Acta Crystallogr F Struct Biol Commun. 2021 Nov 1; 77(Pt 11): 427–434. Published online 2021 Oct 29. doi: 10.1107/S2053230X21010748

PMCID:: PMC8561813

Abstract Article PDF–1.2M

Select item 84841925.

Hepatoblastoma: glutamine depletion hinders cell viability in the embryonal subtype but high GLUL expression is associated with better overall survival

Andreas Schmidt, Angela Armento, Ovidio Bussolati, Martina Chiu, Verena Ellerkamp, Marcus O. Scharpf, Philip Sander, Evi Schmid, Steven W. Warmann, Jörg Fuchs

J Cancer Res Clin Oncol. 2021; 147(11): 3169–3181. Published online 2021 Jul 7. doi: 10.1007/s00432-021-03713-4

PMCID:: PMC8484192

Abstract Article PDF–1.4M

Select item 80967846.

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia

Tra Ly Nguyen, Marie‐Julie Nokin, Silvia Terés, Mercedes Tomé, Clément Bodineau, Oriane Galmar, Jean‐Max Pasquet, Benoit Rousseau, Sebastian van Liempd, Juan Manuel Falcon‐Perez, Elodie Richard, Elodie Muzotte, Hamid‐Reza Rezvani, Muriel Priault, Marion Bouchecareilh, Isabelle Redonnet‐Vernhet, Julien Calvo, Benjamin Uzan, Françoise Pflumio, Patricia Fuentes, Maria L. Toribio, Abdel‐Majid Khatib, Pierre Soubeyran, Piedad del Socorro Murdoch, Raúl V. Durán

Mol Oncol. 2021 May; 15(5): 1412–1431. Published online 2021 Feb 13. doi: 10.1002/1878-0261.12877

PMCID:: PMC8096784

Abstract Article PDF–4.2M

Select item 79582257.

Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

Pei-Yun Tsai, Min-Sik Lee, Unmesh Jadhav, Insia Naqvi, Shariq Madha, Ashley Adler, Meeta Mistry, Sergey Naumenko, Caroline A. Lewis, Daniel S. Hitchcock, Frederick R. Roberts, Peter DelNero, Thomas Hank, Kim C. Honselmann, Vicente Morales Oyarvide, Mari Mino-Kenudson, Clary B. Clish, Ramesh A. Shivdasani, Nada Y. Kalaany

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2003014118. Published online 2021 Mar 2. doi: 10.1073/pnas.2003014118

PMCID:: PMC7958225

Abstract Article PDF–1.9M

Select item 73291948.

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, Lingegowda S. Mangala, Dahai Jiang, Cecil Han, Joelle Baddour, Juan C. Marini, Joseph Ni, Ryuichi Nakahara, Stephen Wahlig, Lisa Chiba, Sun Hye Kim, Joshua Morse, Sunila Pradeep, Archana Sidalaghatta Nagaraja, Monika Haemmerle, Noh Kyunghee, Mathew Derichsweiler, Thomas Plackemeier, Imelda Mercado-Uribe, Gabriel Lopez-Berestein, Tyler Moss, Prahlad T. Ram, Jinsong Liu, Xiongbin Lu, Samuel C. Mok, Anil K. Sood, Deepak Nagrath

Cell Metab. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Cell Metab. 2016 Nov 8; 24(5): 685–700. doi: 10.1016/j.cmet.2016.10.011

PMCID:: PMC7329194

Abstract Article PDF–3.1M

Select item 57564199.

The SNP rs10911021 is associated with oxidative stress in coronary heart disease patients from Pakistan

Saleem Ullah Shahid, Shabana, Steve Humphries

Lipids Health Dis. 2018; 17: 6. Published online 2018 Jan 5. doi: 10.1186/s12944-017-0654-8

PMCID:: PMC5756419

Abstract Article PDF–400K

Select item 571138310.

1,25-Dihydroxyvitamin D Regulation of Glutamine Synthetase and Glutamine Metabolism in Human Mammary Epithelial Cells

Sarah Beaudin, JoEllen Welsh

Endocrinology. 2017 Dec 1; 158(12): 4174–4188. Published online 2017 Sep 28. doi: 10.1210/en.2017-00238

PMCID:: PMC5711383

Abstract Article

Select item 476203211.

Proteomic identification of glutamine synthetase as a differential marker for oligodendrogliomas and astrocytomas: Laboratory investigation

Zhengping Zhuang, Meng Qi, Jie Li, Hiroaki Okamoto, David S. Xu, Rajiv R. Iyer, Jie Lu, Chunzhang Yang, Robert J. Weil, Alexander Vortmeyer, Russell R. Lonser

J Neurosurg. Author manuscript; available in PMC 2016 Feb 22.

Published in final edited form as: J Neurosurg. 2011 Oct; 115(4): 789–795. Published online 2011 Jun 17. doi: 10.3171/2011.5.JNS11451

PMCID:: PMC4762032

Abstract Article PDF–787K

Select item 473749312.

Molecular Mechanisms of Glutamine Synthetase Mutations that Lead to Clinically Relevant Pathologies

Benedikt Frieg, Boris Görg, Nadine Homeyer, Verena Keitel, Dieter Häussinger, Holger Gohlke

PLoS Comput Biol. 2016 Feb; 12(2): e1004693. Published online 2016 Feb 2. doi: 10.1371/journal.pcbi.1004693

PMCID:: PMC4737493

Abstract Article PDF–3.9M

Select item 466368513.

Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Saverio Tardito, Anaïs Oudin, Shafiq U. Ahmed, Fred Fack, Olivier Keunen, Liang Zheng, Hrvoje Miletic, Per Øystein Sakariassen, Adam Weinstock, Allon Wagner, Susan L. Lindsay, Andreas K. Hock, Susan C. Barnett, Eytan Ruppin, Svein Harald Mørkve, Morten Lund-Johansen, Anthony J. Chalmers, Rolf Bjerkvig, Simone P. Niclou, Eyal Gottlieb

Nat Cell Biol. Author manuscript; available in PMC 2016 May 23.

Published in final edited form as: Nat Cell Biol. 2015 Dec; 17(12): 1556–1568. Published online 2015 Nov 23. doi: 10.1038/ncb3272

PMCID:: PMC4663685

Abstract Article PDF–5.5M

Select item 447735514.

Genetic Variant at the GLUL Locus Predicts All-Cause Mortality in Patients With Type 2 Diabetes

Sabrina Prudente, Hetal Shah, Diego Bailetti, Marcus Pezzolesi, Patinut Buranasupkajorn, Luana Mercuri, Christine Mendonca, Salvatore De Cosmo, Monika Niewczas, Vincenzo Trischitta, Alessandro Doria

Diabetes. 2015 Jul; 64(7): 2658–2663. Published online 2015 Feb 12. doi: 10.2337/db14-1653

PMCID:: PMC4477355

Abstract Article PDF–724K

Select item 363551515.

Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme

Anna Rosati, Pietro Luigi Poliani, Alice Todeschini, Manuela Cominelli, Daniela Medicina, Marco Cenzato, Edda Lucia Simoncini, Stefano Maria Magrini, Michela Buglione, Salvatore Grisanti, Alessandro Padovani

Neuro Oncol. 2013 May; 15(5): 618–625. Published online 2013 Feb 14. doi: 10.1093/neuonc/nos338

PMCID:: PMC3635515

Abstract Article PDF–294K

Select item 30608416.

Sequence of a human glutamine synthetase cDNA.

C S Gibbs, K E Campbell, R H Wilson

Nucleic Acids Res. 1987 Aug 11; 15(15): 6293. doi: 10.1093/nar/15.15.6293

PMCID:: PMC306084

Summary Page Browse PDF–105K

Select item 1039630517.

PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma

Song Peng, Ze Wang, Peng Tang, Shuo Wang, Yiqiang Huang, Qiubo Xie, Yapeng Wang, Xintao Tan, Tang Tang, Xuzhi Yan, Jing Xu, Weihua Lan, Luofu Wang, Dianzheng Zhang, Bin Wang, Tiejun Pan, Jun Qin, Jun Jiang, Qiuli Liu

Sci Adv. 2023 Aug; 9(31): eadf3566. Published online 2023 Aug 2. doi: 10.1126/sciadv.adf3566

PMCID:: PMC10396305

Abstract Article PDF–2.7M

Select item 987348118.

Bestrophin-2 and glutamine synthetase form a complex for glutamate release

Aaron P. Owji, Kuai Yu, Alec Kittredge, Jiali Wang, Yu Zhang, Tingting Yang

Nature. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Nature. 2022 Nov; 611(7934): 180–187. Published online 2022 Oct 26. doi: 10.1038/s41586-022-05373-x

PMCID:: PMC9873481

Abstract Article PDF–3.6M

Select item 591698419.

Targeting of glutamine transporter ASCT2 and glutamine synthetase suppresses gastric cancer cell growth

Jianxin Ye, Qiang Huang, Jie Xu, Jinsheng Huang, Jinzhou Wang, Wenjing Zhong, Wannan Chen, Xinjian Lin, Xu Lin

J Cancer Res Clin Oncol. 2018; 144(5): 821–833. Published online 2018 Feb 12. doi: 10.1007/s00432-018-2605-9

PMCID:: PMC5916984

Abstract Article PDF–2.7M

Select item 557523320.

Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

Erika M. Palmieri, Alessio Menga, Rosa Martín-Pérez, Annamaria Quinto, Carla Riera-Domingo, Giacoma De Tullio, Douglas C. Hooper, Wouter H. Lamers, Bart Ghesquière, Daniel W. McVicar, Attilio Guarini, Massimiliano Mazzone, Alessandra Castegna

Cell Rep. 2017 Aug 15; 20(7): 1654–1666. Published online 2017 Aug 15. doi: 10.1016/j.celrep.2017.07.054

PMCID:: PMC5575233

Abstract Article

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Gene

Items: 1 to 20 of 94

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity