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Select item 80388291.

Ssu72 Dual-Specific Protein Phosphatase: From Gene to Diseases

Soeun Hwang, Min-Hee Kim, Chang-Woo Lee

Int J Mol Sci. 2021 Apr; 22(7): 3791. Published online 2021 Apr 6. doi: 10.3390/ijms22073791

PMCID:: PMC8038829

Abstract Article PDF–19M

Select item 64303992.

Functional interaction of human Ssu72 with RNA polymerase II complexes

Benjamin M. Spector, Michael E. Turek, David H. Price

PLoS One. 2019; 14(3): e0213598. Published online 2019 Mar 22. doi: 10.1371/journal.pone.0213598

PMCID:: PMC6430399

Abstract Article PDF–3.6M

Select item 34757993.

An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72

Kehui Xiang, James L. Manley, Liang Tong

Genes Dev. 2012 Oct 15; 26(20): 2265–2270. doi: 10.1101/gad.198853.112

PMCID:: PMC3475799

Abstract Article PDF–851K

Select item 42012874.

A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation

Yupeng Chen, Lirong Zhang, Conchi Estarás, Seung H. Choi, Luis Moreno, Jr., Jonathan Karn, James J. Moresco, John R. Yates, III, Katherine A. Jones

Genes Dev. 2014 Oct 15; 28(20): 2261–2275. doi: 10.1101/gad.250449.114

PMCID:: PMC4201287

Abstract Article PDF–1.7M

Select item 5483355.

Conserved and specific functions of mammalian ssu72

Benoit St-Pierre, Xudong Liu, Lan-Chau T. Kha, Xudong Zhu, Owen Ryan, Zhe Jiang, Eldad Zacksenhaus

Nucleic Acids Res. 2005; 33(2): 464–477. Published online 2005 Jan 19. doi: 10.1093/nar/gki171

PMCID:: PMC548335

Abstract Article PDF–2.8M

Select item 57982966.

Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk

Matthew Bratkowski, Ilona Christy Unarta, Lizhe Zhu, Murtada Shubbar, Xuhui Huang, Xin Liu

J Biol Chem. 2018 Feb 2; 293(5): 1651–1665. Published online 2017 Nov 20. doi: 10.1074/jbc.M117.811521

PMCID:: PMC5798296

Abstract Article PDF–3.6M

Select item 30387897.

Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex

Kehui Xiang, Takashi Nagaike, Song Xiang, Turgay Kilic, Maia M. Beh, James L. Manley, Liang Tong

Nature. Author manuscript; available in PMC 2011 Apr 7.

Published in final edited form as: Nature. 2010 Oct 7; 467(7316): 729–733. Published online 2010 Sep 22. doi: 10.1038/nature09391

PMCID:: PMC3038789

Abstract Article PDF–1.7M

Select item 29641668.

The hsSsu72 phosphatase is a cohesin-binding protein that regulates the resolution of sister chromatid arm cohesion

Hyun-Soo Kim, Kwan-Hyuck Baek, Geun-Hyoung Ha, Jae-Chul Lee, Yu-Na Kim, Janet Lee, Hye-Young Park, Noo Ri Lee, Ho Lee, Yunje Cho, Chang-Woo Lee

EMBO J. 2010 Oct 20; 29(20): 3544–3557. Published online 2010 Sep 3. doi: 10.1038/emboj.2010.217

PMCID:: PMC2964166

Abstract Article PDF–1.5M

Select item 59883129.

SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy

Muyu Xu, James J. Moresco, Max Chang, Amey Mukim, Davey Smith, Jolene K. Diedrich, John R. Yates, III, Katherine A. Jones

PLoS Pathog. 2018 May; 14(5): e1007071. Published online 2018 May 23. doi: 10.1371/journal.ppat.1007071

PMCID:: PMC5988312

Abstract Article PDF–7.6M

Select item 331873010.

Ssu72 Phosphatase-dependent Erasure of Phospho-Ser7 Marks on the RNA Polymerase II C-terminal Domain Is Essential for Viability and Transcription Termination

David W. Zhang, Amber L. Mosley, Sreenivasa R. Ramisetty, Juan B. Rodríguez-Molina, Michael P. Washburn, Aseem Z. Ansari

J Biol Chem. 2012 Mar 9; 287(11): 8541–8551. Published online 2012 Jan 10. doi: 10.1074/jbc.M111.335687

PMCID:: PMC3318730

Abstract Article PDF–2.5M

Select item 391782411.

RNA polymerase II termination involves CTD tyrosine dephosphorylation by CPF subunit Glc7

Amelie Schreieck, Ashley D. Easter, Stefanie Etzold, Katrin Wiederhold, Michael Lidschreiber, Patrick Cramer, Lori A. Passmore

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Nat Struct Mol Biol. 2014 Feb; 21(2): 175–179. Published online 2014 Jan 12. doi: 10.1038/nsmb.2753

PMCID:: PMC3917824

Abstract Article PDF–1.1M

Select item 31107312.

Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs

Yongtao Yu, Chenggang Zhang, Gangqiao Zhou, Songfeng Wu, Xianghu Qu, Handong Wei, Guichun Xing, Chunna Dong, Yun Zhai, Jinghong Wan, Shuguang Ouyang, Li Li, Shaowen Zhang, Kaixin Zhou, Yinan Zhang, Chutse Wu, Fuchu He

Genome Res. 2001 Aug; 11(8): 1392–1403. doi: 10.1101/gr.175501

PMCID:: PMC311073

Abstract Article PDF–142K

Select item 866666513.

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

Jean-Philippe Guégan, Justine Pollet, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Marcus E. Peter, Patrick Legembre

iScience. 2021 Dec 17; 24(12): 103538. Published online 2021 Dec 1. doi: 10.1016/j.isci.2021.103538

PMCID:: PMC8666665

Abstract Article PDF–3.2M

Select item 31093414.

Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells

Qing-Hua Zhang, Min Ye, Xin-Yan Wu, Shuang-Xi Ren, Meng Zhao, Chun-Jun Zhao, Gang Fu, Yu Shen, Hui-Yong Fan, Gang Lu, Ming Zhong, Xiang-Ru Xu, Ze-Guang Han, Ji-Wang Zhang, Jiong Tao, Qiu-Hua Huang, Jun Zhou, Geng-Xi Hu, Jian Gu, Sai-Juan Chen, Zhu Chen

Genome Res. 2000 Oct; 10(10): 1546–1560. doi: 10.1101/gr.140200

PMCID:: PMC310934

Abstract Article PDF–1.3M

Select item 939206315.

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li

Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z

PMCID:: PMC9392063

Abstract Article PDF–2.0M

Select item 760600816.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 615850717.

KAP1 facilitates reinstatement of heterochromatin after DNA replication

Suk Min Jang, Annamaria Kauzlaric, Jean-Pierre Quivy, Julien Pontis, Benjamin Rauwel, Andrea Coluccio, Sandra Offner, Julien Duc, Priscilla Turelli, Geneviève Almouzni, Didier Trono

Nucleic Acids Res. 2018 Sep 28; 46(17): 8788–8802. Published online 2018 Jun 28. doi: 10.1093/nar/gky580

PMCID:: PMC6158507

Abstract Article PDF–9.4M

Select item 933831318.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4