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Select item 99328141.

Quantitative trait loci on chromosomes 9 and 19 modulate AII amacrine cell number in the mouse retina

Bridget Kulesh, Rachel Bozadjian, Ryan J. Parisi, Stephanie A. Leong, Amanda G. Kautzman, Benjamin E. Reese, Patrick W. Keeley

Front Neurosci. 2023; 17: 1078168. Published online 2023 Feb 2. doi: 10.3389/fnins.2023.1078168

PMCID:: PMC9932814

Abstract Article PDF–14M

Select item 31447902.

Crystallographic characterization of the DIX domain of the Wnt signalling positive regulator Ccd1

Shin-ichi Terawaki, Koumei Yano, Takuya Katsutani, Kensuke Shiomi, Kazuko Keino-Masu, Masayuki Masu, Yasuhito Shomura, Hirofumi Komori, Naoki Shibata, Yoshiki Higuchi

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jul 1; 67(Pt 7): 758–761. Published online 2011 Jun 30. doi: 10.1107/S1744309111016526

PMCID:: PMC3144790

Abstract Article PDF–271K

Select item 57110203.

Adiposity QTL Adip20 decomposes into at least four loci when dissected using congenic strains

Cailu Lin, Brad D. Fesi, Michael Marquis, Natalia P. Bosak, Anna Lysenko, Mohammed Amin Koshnevisan, Fujiko F. Duke, Maria L. Theodorides, Theodore M. Nelson, Amanda H. McDaniel, Mauricio Avigdor, Charles J. Arayata, Lauren Shaw, Alexander A. Bachmanov, Danielle R. Reed

PLoS One. 2017; 12(12): e0188972. Published online 2017 Dec 1. doi: 10.1371/journal.pone.0188972

PMCID:: PMC5711020

Abstract Article PDF–13M

Select item 55528524.

Structural basis for Ccd1 auto-inhibition in the Wnt pathway through homomerization of the DIX domain

Shin-ichi Terawaki, Shohei Fujita, Takuya Katsutani, Kensuke Shiomi, Kazuko Keino-Masu, Masayuki Masu, Kaori Wakamatsu, Naoki Shibata, Yoshiki Higuchi

Sci Rep. 2017; 7: 7739. Published online 2017 Aug 10. doi: 10.1038/s41598-017-08019-5

PMCID:: PMC5552852

Abstract Article PDF–4.9M

Select item 88301285.

DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis

Yeaji Kim, Dong Young Kim, Haiying Zhang, Cho-Rong Bae, Daehyeon Seong, Yeomyung Kim, Jaewhan Song, Young-Myeong Kim, Young-Guen Kwon

BMC Biol. 2022; 20: 41. Published online 2022 Feb 10. doi: 10.1186/s12915-022-01240-3

PMCID:: PMC8830128

Abstract Article PDF–3.9M

Select item 33094846.

Abnormal behavior in mice mutant for the Disc1 binding partner, Dixdc1

S Kivimäe, P-M Martin, D Kapfhamer, Y Ruan, U Heberlein, J L R Rubenstein, B N R Cheyette

Transl Psychiatry. 2011 Sep; 1(9): e43. Published online 2011 Sep 27. doi: 10.1038/tp.2011.41

PMCID:: PMC3309484

Abstract Article PDF–332K

Select item 30487427.

Molecular Basis of Wnt Activation via the DIX Domain Protein Ccd1

Yi-Tong Liu, Qiong-Jie Dan, Jiawei Wang, Yingang Feng, Lei Chen, Juan Liang, Qinxi Li, Sheng-Cai Lin, Zhi-Xin Wang, Jia-Wei Wu

J Biol Chem. 2011 Mar 11; 286(10): 8597–8608. Published online 2010 Dec 28. doi: 10.1074/jbc.M110.186742

PMCID:: PMC3048742

Abstract Article PDF–3.8M

Select item 29380138.

Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

Karun K. Singh, Xuecai Ge, Yingwei Mao, Laurel Drane, Konstantinos Meletis, Benjamin A. Samuels, Li-Huei Tsai

Neuron. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Neuron. 2010 Jul 15; 67(1): 33–48. doi: 10.1016/j.neuron.2010.06.002

PMCID:: PMC2938013

Abstract Article PDF–4.3M

Select item 61976939.

FoxO6 regulates Hippo signaling and growth of the craniofacial complex

Zhao Sun, Clarissa S. G. da Fontoura, Myriam Moreno, Nathan E. Holton, Mason Sweat, Yan Sweat, Myoung Keun Lee, Jed Arbon, Felicitas B. Bidlack, Daniel R. Thedens, Peggy Nopoulos, Huojun Cao, Steven Eliason, Seth M. Weinberg, James F. Martin, Lina Moreno-Uribe, Brad A. Amendt

PLoS Genet. 2018 Oct; 14(10): e1007675. Published online 2018 Oct 4. doi: 10.1371/journal.pgen.1007675

PMCID:: PMC6197693

Abstract Article PDF–31M

Select item 964299810.

A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene

Yonghe Ding, Di Lang, Jianhua Yan, Haisong Bu, Hongsong Li, Kunli Jiao, Jingchun Yang, Haibo Ni, Stefano Morotti, Tai Le, Karl J Clark, Jenna Port, Stephen C Ekker, Hung Cao, Yuji Zhang, Jun Wang, Eleonora Grandi, Zhiqiang Li, Yongyong Shi, Yigang Li, Alexey V Glukhov, Xiaolei Xu

eLife. 2022; 11: e77327. Published online 2022 Oct 18. doi: 10.7554/eLife.77327

PMCID:: PMC9642998

Abstract Article PDF–2.1M

Select item 326557711.

Conditional ablation of the Notch2 receptor in the ocular lens

Senthil S. Saravanamuthu, Tien T. Le, Chun Y. Gao, Radu I. Cojocaru, Pushpa Pandiyan, Chunqiao Liu, Jun Zhang, Peggy S. Zelenka, Nadean L. Brown

Dev Biol. Author manuscript; available in PMC 2013 Feb 15.

Published in final edited form as: Dev Biol. 2012 Feb 15; 362(2): 219–229. Published online 2011 Nov 29. doi: 10.1016/j.ydbio.2011.11.011

PMCID:: PMC3265577

Abstract Article PDF–2.4M

Select item 564508212.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 43978313.

Genomic Analysis of Mouse Retinal Development

Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko

PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247

PMCID:: PMC439783

Abstract Article PDF–975K

Select item 529582114.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 396495515.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 831323916.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 1091766017.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 28355419.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Abstract Article PDF–481K

Select item 302253420.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

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