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Select item 111370191.

G protein-specific mechanisms in the serotonin 5-HT_2A receptor regulate psychosis-related effects and memory deficits

Elk Kossatz, Rebeca Diez-Alarcia, Supriya A. Gaitonde, Carla Ramon-Duaso, Tomasz Maciej Stepniewski, David Aranda-Garcia, Itziar Muneta-Arrate, Elodie Tepaz, Suwipa Saen-Oon, Robert Soliva, Aida Shahraki, David Moreira, Jose Brea, Maria Isabel Loza, Rafael de la Torre, Peter Kolb, Michel Bouvier, J. Javier Meana, Patricia Robledo, Jana Selent

Nat Commun. 2024; 15: 4307. Published online 2024 May 29. doi: 10.1038/s41467-024-48196-2

PMCID:: PMC11137019

Abstract Article PDF–2.7M

Select item 110456502.

Fibroblast expression of neurotransmitter receptor HTR2A associates with inflammation in rheumatoid arthritis joint

Chunyan Xiang, Soon-Min Hong, Bingjiao Zhao, Hui Pi, Fang Du, Xingyu Lu, Yuanjia Tang, Nan Shen, Chunxi Yang, Runci Wang

Clin Exp Med. 2024; 24(1): 84. Published online 2024 Apr 25. doi: 10.1007/s10238-024-01352-w

PMCID:: PMC11045650

Abstract Article PDF–7.5M

Select item 109889273.

Interaction between HTR2A rs3125 and negative life events in suicide attempts among patients with major depressive disorder: a cross-sectional study

Jian-Yue Pang, Yi-Ping Wang, Hui-Min Teng, Jin He, Rui Luo, Si-Meng Feng, Wei-Hua Yue, Heng-Fen Li

BMC Psychiatry. 2024; 24: 249. Published online 2024 Apr 2. doi: 10.1186/s12888-024-05713-3

PMCID:: PMC10988927

Abstract Article PDF–1.1M

Select item 106472454.

In Vivo Serotonin 5-HT2A Receptor Availability and Its Relationship with Aggression Traits in Healthy Individuals: A Positron Emission Tomography Study with C-11 MDL100907

Jeong-Hee Kim, Hang-Keun Kim, Young-Don Son, Jong-Hoon Kim

Int J Mol Sci. 2023 Nov; 24(21): 15697. Published online 2023 Oct 28. doi: 10.3390/ijms242115697

PMCID:: PMC10647245

Abstract Article PDF–2.5M

Select item 105102975.

Association between the rs6313 polymorphism in the 5-HTR2A gene and the efficacy of antipsychotic drugs

Yulong Wang, Xingru Tan, Zhoufangyuan Chen, Bide Zhang, Yunzhi Gao, Yanlong Wang

BMC Psychiatry. 2023; 23: 682. Published online 2023 Sep 19. doi: 10.1186/s12888-023-05165-1

PMCID:: PMC10510297

Abstract Article PDF–2.0M

Select item 97633046.

Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis

Jianan Zhao, Lingxia Xu, Cen Chang, Ping Jiang, Kai Wei, Yiming Shi, Linshuai Xu, Yixin Zheng, Yu Shan, Yanqin Bian, Li Li, Shicheng Guo, Steven J. Schrodi, Rongsheng Wang, Dongyi He

Front Immunol. 2022; 13: 1054451. Published online 2022 Dec 6. doi: 10.3389/fimmu.2022.1054451

PMCID:: PMC9763304

Abstract Article PDF–4.8M

Select item 95430497.

Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse

Aysheh Alrfooh, Ryan M. Smith

Epigenetics. 2022; 17(10): 1246–1258. Published online 2021 Nov 23. doi: 10.1080/15592294.2021.2005277

PMCID:: PMC9543049

Abstract Article PDF–978K

Select item 94445248.

Polymorphisms in the 5-HTR2A gene related to obstructive sleep apnea syndrome

Vânia Belintani Piatto, Thiago Bittencourt Ottoni de Carvalho, Nely Silva Aragão de Marchi, Fernando Drimel Molina, José Victor Maniglia

Braz J Otorhinolaryngol. 2011 May-Jun; 77(3): 348–355. Published online 2015 Oct 19. doi: 10.1590/S1808-86942011000300013

PMCID:: PMC9444524

Abstract Article PDF–240K

Select item 92086629.

ELEVATED 5-HT 2A RECEPTORS IN POSTMORTEM PREFRONTAL CORTEX IN MAJOR DEPRESSION IS ASSOCIATED WITH REDUCED ACTIVITY OF PROTEIN KINASE A

R. C. SHELTON, E. SANDERS-BUSH, D. H. MANIER, D. A. LEWIS

Neuroscience. Author manuscript; available in PMC 2022 Jun 20.

Published in final edited form as: Neuroscience. 2009 Feb 18; 158(4): 1406–1415. Published online 2008 Dec 3. doi: 10.1016/j.neuroscience.2008.11.036

PMCID:: PMC9208662

Abstract Article PDF–437K

Select item 874537610.

Possible association of serotonin 2A receptor gene (HTR2A) regulatory variants with severity of depression symptoms in children with autism spectrum disorder

Kenneth D. Gadow, Ryan M. Smith, Julia K. Pinsonneault

Cogn Behav Neurol. Author manuscript; available in PMC 2022 Jan 10.

Published in final edited form as: Cogn Behav Neurol. 2014 Jun; 27(2): 107–116. doi: 10.1097/WNN.0000000000000028

PMCID:: PMC8745376

Abstract Article PDF–532K

Select item 849287611.

Serotonin 5-HT_2A receptor activity mediates adipocyte differentiation through control of adipogenic gene expression

Bangning Yu, Diana M. Battaglia, Timothy P. Foster, Charles D. Nichols

Sci Rep. 2021; 11: 19714. Published online 2021 Oct 5. doi: 10.1038/s41598-021-98970-1

PMCID:: PMC8492876

Abstract Article PDF–1.7M

Select item 813794712.

Opposite alterations of 5HT_2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile

Rebeca Diez-Alarcia, Carolina Muguruza, Guadalupe Rivero, Aintzane García-Bea, Vanessa Gómez-Vallejo, Luis F. Callado, Jordi Llop, Abraham Martín, J. Javier Meana

Transl Psychiatry. 2021; 11: 302. Published online 2021 May 20. doi: 10.1038/s41398-021-01430-7

PMCID:: PMC8137947

Abstract Article PDF–940K

Select item 774772113.

Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients

Vicki E. Maltby, Rodney A. Lea, Sean Burnard, Alexandre Xavier, Thao Van Cao, Nicole White, Daniel Kennedy, Kira Groen, Katherine A. Sanders, Rebecca Seeto, Samara Bray, Melissa Gresle, Louise Laverick, Helmut Butzkueven, Rodney J. Scott, Jeannette Lechner-Scott

Sci Rep. 2020; 10: 22217. Published online 2020 Dec 17. doi: 10.1038/s41598-020-78809-x

PMCID:: PMC7747721

Abstract Article PDF–1.4M

Select item 772878614.

Serotonin 2A (5-HT_2A) receptor affects cell–matrix adhesion and the formation and maintenance of stress fibers in HEK293 cells

Joe Anand Kumar John Jayakumar, Mitradas. M. Panicker, Basudha Basu

Sci Rep. 2020; 10: 21675. Published online 2020 Dec 10. doi: 10.1038/s41598-020-78595-6

PMCID:: PMC7728786

Abstract Article PDF–1.5M

Select item 759381615.

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT_2A Serotonin Receptor

Kuglae Kim, Tao Che, Ouliana Panova, Jeffrey F. DiBerto, Jiankun Lyu, Brian E. Krumm, Daniel Wacker, Michael J. Robertson, Alpay B. Seven, David E. Nichols, Brian K. Shoichet, Georgios Skiniotis, Bryan L. Roth

Cell. Author manuscript; available in PMC 2021 Sep 17.

Published in final edited form as: Cell. 2020 Sep 17; 182(6): 1574–1588.e19. doi: 10.1016/j.cell.2020.08.024

PMCID:: PMC7593816

Abstract Article PDF–3.1M

Select item 755507116.

Common HTR2A variants and 5‐HTTLPR are not associated with human in vivo serotonin 2A receptor levels

Marie Spies, Arafat Nasser, Brice Ozenne, Peter S. Jensen, Gitte M. Knudsen, Patrick M. Fisher

Hum Brain Mapp. 2020 Nov; 41(16): 4518–4528. Published online 2020 Jul 22. doi: 10.1002/hbm.25138

PMCID:: PMC7555071

Abstract Article PDF–1.3M

Select item 694388917.

Association between serotonin 2A receptor (HTR2A) genetic variations and risk of hypertension in a community-based cohort study

Jung Ran Choi, Minhee Jeon, Sang Baek Koh

BMC Med Genet. 2020; 21: 5. Published online 2020 Jan 6. doi: 10.1186/s12881-019-0927-3

PMCID:: PMC6943889

Abstract Article PDF–774K

Select item 670878518.

Genome-wide association study in irradiated childhood cancer survivors identifies HTR2A for subsequent basal cell carcinoma

Yadav Sapkota, Lucie M. Turcotte, Matthew J. Ehrhardt, Rebecca M. Howell, Michael A. Arnold, Carmen L. Wilson, Wendy Leisenring, Zhaoming Wang, Joshua Sampson, Casey L. Dagnall, Eric Karlins, Shengchao Alfred Li, Belynda D. Hicks, Rita Weathers, Susan A. Smith, Kyla Shelton, Qi Liu, Margaret A. Tucker, Stephen J. Chanock, Jinghui Zhang, Melissa M. Hudson, Joseph P. Neglia, Gregory T. Armstrong, Leslie L. Robison, Lindsay M. Morton, Smita Bhatia, Yutaka Yasui

J Invest Dermatol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: J Invest Dermatol. 2019 Sep; 139(9): 2042–2045.e8. Published online 2019 Mar 22. doi: 10.1016/j.jid.2019.02.029

PMCID:: PMC6708785

Article PDF–279K

Select item 664768619.

Rs 6313 polymorphism in 5‐hydroxytryptamine receptor 2A gene association with polysymptomatic primary nocturnal enuresis

Chang‐Ching Wei, Lei Wan, Wen‐Yuan Lin, Fuu‐Jen Tsai

J Clin Lab Anal. 2010; 24(6): 371–375. Published online 2010 Nov 18. doi: 10.1002/jcla.20386

PMCID:: PMC6647686

Abstract Article PDF–92K

Select item 662547420.

Genetic association analysis of 5‐HTR2A gene variants in eating disorders in a Mexican population

Alma Delia Genis‐Mendoza, David Ruiz‐Ramos, María Lilia López‐Narvaez, Carlos Alfonso Tovilla‐Zárate, Ana Rosa García, Gabriela Cortes Meda, José Jaime Martinez‐Magaña, Thelma Beatriz González‐Castro, Isela Esther Juárez‐Rojop, Humberto Nicolini

Brain Behav. 2019 Jul; 9(7): e01286. Published online 2019 Jun 14. doi: 10.1002/brb3.1286

PMCID:: PMC6625474

Abstract Article PDF–443K

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