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Items: 1 to 20 of 81

1.
Upregulated Expression of IL2RB Causes Disorder of Immune Microenvironment in Patients with Kawasaki Disease
Yunfei Liao, Ben Ke, Xiaoyan Long, Jianjun Xu, Yongbing Wu
Biomed Res Int. 2022; 2022: 2114699. Published online 2022 Jul 25. doi: 10.1155/2022/2114699
PMCID:
PMC9343205
AbstractArticlePDF–1.9M
2.
Oxalate upregulates expression of IL-2Rβ and activates IL-2R signaling in HK-2 cells, a line of human renal epithelial cells
Sweaty Koul, Lakshmipathi Khandrika, Thomas J. Pshak, Naoko Iguchi, Mintu Pal, Joshua J. Steffan, Hari K. Koul
Am J Physiol Renal Physiol. 2014 May 1; 306(9): F1039–F1046. Published online 2014 Feb 12. doi: 10.1152/ajprenal.00462.2013
PMCID:
PMC4010678
AbstractArticle
3.
Abnormal Expression Pattern of the IL-2 Receptor β-Chain on CD4+ T Cells in ANCA-Associated Vasculitis
Benjamin Wilde, André Hoerning, Andreas Kribben, Oliver Witzke, Sebastian Dolff
Dis Markers. 2014; 2014: 249846. Published online 2014 Feb 9. doi: 10.1155/2014/249846
PMCID:
PMC3933302
AbstractArticlePDF–2.1M
4.
Ectodomain Shedding of Interleukin-2 Receptor β and Generation of an Intracellular Functional Fragment
Pavel Montes de Oca B., Valerie Malardé, Richard Proust, Alice Dautry-Varsat, Franck Gesbert
J Biol Chem. 2010 Jul 16; 285(29): 22050–22058. Published online 2010 May 21. doi: 10.1074/jbc.M109.093088
PMCID:
PMC2903380
AbstractArticlePDF–1.1M
5.
The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction.
T Miyazaki, M Maruyama, G Yamada, M Hatakeyama, T Taniguchi
EMBO J. 1991 Nov; 10(11): 3191–3197. doi: 10.1002/j.1460-2075.1991.tb04881.x
PMCID:
PMC453042
SummaryPage BrowsePDF–1.2M
6.
Soluble IL-2R Levels at Baseline Predict the Development of Severe Respiratory Failure and Mortality in COVID-19 Patients
Nikolaos K. Gatselis, Vasiliki Lygoura, Aggeliki Lyberopoulou, George Giannoulis, Anna Samakidou, Antonia Vaiou, George Vatidis, Katerina Antoniou, Aggelos Stefos, Sarah Georgiadou, Dimitrios Sagris, Dafni Sveroni, Despoina Stergioula, Stella Gabeta, George Ntaios, George N. Dalekos
Viruses. 2022 Apr; 14(4): 787. Published online 2022 Apr 10. doi: 10.3390/v14040787
PMCID:
PMC9025750
AbstractArticlePDF–589K
7.
IL‐2 gene C/T polymorphism is associated with prostate cancer
Hsi‐Chin Wu, Chao‐Hsiang Chang, Lei Wan, Chao‐I Wu, Fuu‐Jen Tsai, Wen‐Chi Chen
J Clin Lab Anal. 2006; 20(6): 245–249. Published online 2006 Nov 17. doi: 10.1002/jcla.20149
PMCID:
PMC6807315
AbstractArticlePDF–121K
8.
Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance
Zinan Zhang, Florian Gothe, Perrine Pennamen, John R. James, David McDonald, Carlos P. Mata, Yorgo Modis, Anas M. Alazami, Meghan Acres, Wolfram Haller, Claire Bowen, Rainer Döffinger, Jan Sinclair, Shannon Brothers, Yu Zhang, Helen F. Matthews, Sophie Naudion, Fanny Pelluard, Huda Alajlan, Yasuhiro Yamazaki, Luigi D. Notarangelo, James E. Thaventhiran, Karin R. Engelhardt, Hamoud Al-Mousa, Sophie Hambleton, Caroline Rooryck, Kenneth G.C. Smith, Michael J. Lenardo
J Exp Med. 2019 Jun 3; 216(6): 1311–1327. Published online 2019 Apr 30. doi: 10.1084/jem.20182304
PMCID:
PMC6547869
AbstractArticlePDF–3.6M
9.
A novel human IL2RB mutation results in T and NK cell–driven immune dysregulation
Isabel Z. Fernandez, Ryan M. Baxter, Josselyn E. Garcia-Perez, Elena Vendrame, Thanmayi Ranganath, Daniel S. Kong, Karl Lundquist, Tom Nguyen, Sidney Ogolla, Jennifer Black, Csaba Galambos, James C. Gumbart, Noor Dawany, Judith R. Kelsen, Edwin F. de Zoeten, Ralph Quinones, Hesham Eissa, Michael R. Verneris, Kathleen E. Sullivan, Rosemary Rochford, Catherine A. Blish, Ross M. Kedl, Cullen M. Dutmer, Elena W.Y. Hsieh
J Exp Med. 2019 Jun 3; 216(6): 1255–1267. Published online 2019 Apr 30. doi: 10.1084/jem.20182015
Correction in:
J Exp Med. 2019 Jun 3; 216(6): 1465.
PMCID:
PMC6547857
AbstractArticlePDF–2.9M
10.
Tethering IL2 to its receptor IL2Rβ enhances anti-tumor activity and expansion of natural killer NK92 cells
Youssef Jounaidi, Joseph F. Cotten, Keith W. Miller, Stuart A. Forman
Cancer Res. Author manuscript; available in PMC 2018 Oct 28.
Published in final edited form as: Cancer Res. 2017 Nov 1; 77(21): 5938–5951. Published online 2017 Sep 15. doi: 10.1158/0008-5472.CAN-17-1007
PMCID:
PMC6204197
AbstractArticlePDF–2.3M
11.
Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules
Blanca E. Ruiz-Medina, Jeremy A. Ross, Robert A. Kirken
J Biol Chem. 2015 Aug 21; 290(34): 20972–20983. Published online 2015 Jul 7. doi: 10.1074/jbc.M115.660654
PMCID:
PMC4543656
AbstractArticlePDF–1.7M
12.
Multistage analysis of variants in the Inflammation pathway and lung cancer risk in smokers
Margaret R. Spitz, Ivan P. Gorlov, Qiong Dong, Xifeng Wu, Wei Chen, David W. Chang, Carol J. Etzel, Neil E. Caporaso, Yang Zhao, David C. Christiani, Paul Brennan, Demetrius Albanes, Jianxin Shi, Michael Thun, Maria Teresa Landi, Christopher I. Amos
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2012 Nov 2.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7): 1213–1221. Published online 2012 May 9. doi: 10.1158/1055-9965.EPI-12-0352-T
PMCID:
PMC3487592
AbstractArticlePDF–1.0M
13.
Soluble Cytokine Receptors (sIL-2Rα, sIL-2Rβ) Induce Subunit-Specific Behavioral Responses and Accumulate in the Cerebral Cortex and Basal Forebrain
Steven S. Zalcman, Ankur Patel, Ruchika Mohla, Youhua Zhu, Allan Siegel
PLoS One. 2012; 7(4): e36316. Published online 2012 Apr 27. doi: 10.1371/journal.pone.0036316
PMCID:
PMC3338652
AbstractArticlePDF–4.3M
14.
Placenta-specific Expression of the Interleukin-2 (IL-2) Receptor β Subunit from an Endogenous Retroviral Promoter
Carla J. Cohen, Rita Rebollo, Sonja Babovic, Elizabeth L. Dai, Wendy P. Robinson, Dixie L. Mager
J Biol Chem. 2011 Oct 14; 286(41): 35543–35552. Published online 2011 Aug 24. doi: 10.1074/jbc.M111.227637
PMCID:
PMC3195601
AbstractArticlePDF–1.3M
15.
Late Expression of Granulysin by Microbicidal CD4+ T Cells Requires PI3K- and STAT5-Dependent Expression of IL-2Rβ That Is Defective in HIV-Infected Patients
Chun Fu Zheng, Gareth J. Jones, Meiqing Shi, Jeremy C. D. Wiseman, Kaleb J. Marr, Byron M. Berenger, Shaunna M. Huston, M. John Gill, Alan M. Krensky, Paul Kubes, Christopher H. Mody
J Immunol. Author manuscript; available in PMC 2009 Jun 1.
Published in final edited form as: J Immunol. 2008 Jun 1; 180(11): 7221–7229. doi: 10.4049/jimmunol.180.11.7221
PMCID:
PMC2661617
AbstractArticlePDF–1.1M
16.
The human interleukin-2 receptor beta-chain gene: genomic organization, promoter analysis and chromosomal assignment.
H Shibuya, M Yoneyama, Y Nakamura, H Harada, M Hatakeyama, S Minamoto, T Kono, T Doi, R White, T Taniguchi
Nucleic Acids Res. 1990 Jul 11; 18(13): 3697–3703. doi: 10.1093/nar/18.13.3697
PMCID:
PMC331067
SummaryPage BrowsePDF–1.3M
17.
The human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surface.
J C Mulloy, R W Crownley, J Fullen, W J Leonard, G Franchini
J Virol. 1996 Jun; 70(6): 3599–3605. doi: 10.1128/jvi.70.6.3599-3605.1996
PMCID:
PMC190235
SummaryPDF–494K
18.
Human interleukin 2 receptor beta-chain gene: chromosomal localization and identification of 5' regulatory sequences.
J R Gnarra, H Otani, M G Wang, O W McBride, M Sharon, W J Leonard
Proc Natl Acad Sci U S A. 1990 May; 87(9): 3440–3444. doi: 10.1073/pnas.87.9.3440
PMCID:
PMC53916
SummaryPage BrowsePDF–1.5M
19.
Interleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell line.
T Torigoe, H U Saragovi, J C Reed
Proc Natl Acad Sci U S A. 1992 Apr 1; 89(7): 2674–2678. doi: 10.1073/pnas.89.7.2674
PMCID:
PMC48724
SummaryPage BrowsePDF–1.3M
20.
Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction.
N Kobayashi, T Kono, M Hatakeyama, Y Minami, T Miyazaki, R M Perlmutter, T Taniguchi
Proc Natl Acad Sci U S A. 1993 May 1; 90(9): 4201–4205. doi: 10.1073/pnas.90.9.4201
PMCID:
PMC46474
SummaryPage BrowsePDF–1.5M

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